Location via proxy:   [ UP ]  
[Report a bug]   [Manage cookies]                
Scribd Logo
Upload

Welcome to Scribd!

  • 570 views

    Expirement No 1

    Uploaded by

    Rajiv Kharbanda
    The document describes an experiment to prepare benzanilide from benzoyl chloride and aniline using the Schotten-Bouman reaction. Aniline and benzoyl chloride are reacted in the presence of sodium hydroxide. The theoretical yield of benzanilide is calculated to be 11.01g based on the amounts of reactants used. The observed yield obtained is 8.8g, giving a percentage yield of 79.92%. Characterization of the product is done using UV, IR, NMR spectroscopy and melting point determination.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd

    Expirement No 1

    Uploaded by

    Rajiv Kharbanda
    570 views4 pages
    The document describes an experiment to prepare benzanilide from benzoyl chloride and aniline using the Schotten-Bouman reaction. Aniline and benzoyl chloride are reacted in the presence of sodium hydroxide. The theoretical yield of benzanilide is calculated to be 11.01g based on the amounts of reactants used. The observed yield obtained is 8.8g, giving a percentage yield of 79.92%. Characterization of the product is done using UV, IR, NMR spectroscopy and melting point determination.

    Original Description:

    eperiment 1

    Copyright

    © © All Rights Reserved

    Available Formats

    DOCX, PDF, TXT or read online from Scribd

    Did you find this document useful?

    Is this content inappropriate?

    The document describes an experiment to prepare benzanilide from benzoyl chloride and aniline using the Schotten-Bouman reaction. Aniline and benzoyl chloride are reacted in the presence of sodium hydroxide. The theoretical yield of benzanilide is calculated to be 11.01g based on the amounts of reactants used. The observed yield obtained is 8.8g, giving a percentage yield of 79.92%. Characterization of the product is done using UV, IR, NMR spectroscopy and melting point determination.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    570 views4 pages

    Expirement No 1

    Uploaded by

    Rajiv Kharbanda
    The document describes an experiment to prepare benzanilide from benzoyl chloride and aniline using the Schotten-Bouman reaction. Aniline and benzoyl chloride are reacted in the presence of sodium hydroxide. The theoretical yield of benzanilide is calculated to be 11.01g based on the amounts of reactants used. The observed yield obtained is 8.8g, giving a percentage yield of 79.92%. Characterization of the product is done using UV, IR, NMR spectroscopy and melting point determination.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    of 4

    EXPIREMENT NO.

    :- 1

    AIM:- To prepare benzanilide from benzoyl chloride (Schotten-Bouman Reaction)


    Requirement:- Aniline = 5.2g , NaOH = 45ml (10g in 100ml H2O) , Benzoyl chloride = 8.5g ,
    Alcohol = 8.5g
    Theory :- The Schotten-Bouman reaction is a method to synthesise amides from amines and acid chlorides.
    Sometimes the name for this reaction also used to indicates the reaction b/w an acid chlorides and an
    alcohol to form an ester . The first reaction was first described in 1883 by German Chemist Carl Schotten
    and Eugen Bauman.
    Reaction:-
    C6H5NH2 + C6H5COCl + NaOH C6H5NHCOC6H5 + NaCl + H2O
    Mechanism:-

    C6H5
    -H O
    C6H5C -C l
    C6H5NH2 + Cl C6H5 NH3 C Cl C6H5 NH C C6H5 C6H5NHCOC6H5
    O O
    Cl

    Procedure:-
    1) Took 5.2g of aniline 8.45ml of NaOH in a stappered flask.
    2)Add benzoyl chloride shake vigrously for 15-20min, flask becomes hot.
    3) Reaction completed when there is no smell of benzoyl chloride, then stop shaking.
    4)Product was separated out as white. Product was checked whether alkaline or not.
    5) 100ml of cold water was added and then filtered with buchner funnel washed with cold water.
    Application:-
    These reaction condition are widely used today in organic chemistry.
    Examples:-
    1) To synthesize capsaiem.
    2) To synthesis benzamide.
    3)Acetylation of benzylamine with acetyi chloride in the Fischer peptide synthesis.
    Precaution:-
    1)Carefully shake the bottle containing chemicals.
    2) Stop shaking only after the smell at benzoyl chloride not felt.
    3) Carefully handle the glass apparatus.
    4) Wear lab coat and gloves.
    Observation:-

    Name of Compound Benzoyl Chloride Aniline Sodium Hydroxide


    Mol. Formula C6H5COCl C6H5NH5 NaOH
    Mol. Mass 140.5 93 40
    Weight Taken (g) 8.5 6.2 4.5
    Volume Taken 7.024 6.089 4.5
    Moles .060 0.055 0.11
    Density

    Calculation:-
    92g of aniline gives = 197g of benzanilide
    1g of aniline gives = 197/92 of benzanilide
    5.2g of aniline gives = (197/92)*5.2 of benzanilide
    = 11.01g
    Observed yield = 8.8 gm
    %age yield = 79.92%

    UV Spectrum:-

    IR Spectrum:-
    NMR:-

    Result:-
    Theoretical Yield =11.01gm
    Observed Yield =8.8gm
    Observed M.pt =1580C
    Literature M.pt =1630C
    %age yield =79.92%

    You might also like