Location via proxy:   [ UP ]  
[Report a bug]   [Manage cookies]                
Scribd Logo
Upload

Welcome to Scribd!

  • 2K views

    Drug Study - Cisplatin

    Uploaded by

    Danielle Aglusolos
    Cisplatin is an antineoplastic drug that inhibits DNA synthesis, causing cross-linking of parent DNA strands and death of rapidly replicating cells. It is indicated for metastatic testicular and ovarian carcinoma, advanced bladder cancer, head and neck cancer, cervical cancer, lung cancer, and other tumors. Common side effects include nausea, vomiting, diarrhea, nephrotoxicity, ototoxicity, alopecia, hypocalcemia, hypokalemia, hypomagnesemia, leukopenia, thrombocytopenia, anemia, and peripheral neuropathy. Nurses monitor for side effects, ensure adequate hydration and electrolyte replacement, and assess the IV site frequently during administration.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd

    Drug Study - Cisplatin

    Uploaded by

    Danielle Aglusolos
    2K views3 pages
    Cisplatin is an antineoplastic drug that inhibits DNA synthesis, causing cross-linking of parent DNA strands and death of rapidly replicating cells. It is indicated for metastatic testicular and ovarian carcinoma, advanced bladder cancer, head and neck cancer, cervical cancer, lung cancer, and other tumors. Common side effects include nausea, vomiting, diarrhea, nephrotoxicity, ototoxicity, alopecia, hypocalcemia, hypokalemia, hypomagnesemia, leukopenia, thrombocytopenia, anemia, and peripheral neuropathy. Nurses monitor for side effects, ensure adequate hydration and electrolyte replacement, and assess the IV site frequently during administration.

    Original Title

    Drug Study -cisplatin.docx

    Copyright

    © © All Rights Reserved

    Available Formats

    DOCX, PDF, TXT or read online from Scribd

    Did you find this document useful?

    Is this content inappropriate?

    Cisplatin is an antineoplastic drug that inhibits DNA synthesis, causing cross-linking of parent DNA strands and death of rapidly replicating cells. It is indicated for metastatic testicular and ovarian carcinoma, advanced bladder cancer, head and neck cancer, cervical cancer, lung cancer, and other tumors. Common side effects include nausea, vomiting, diarrhea, nephrotoxicity, ototoxicity, alopecia, hypocalcemia, hypokalemia, hypomagnesemia, leukopenia, thrombocytopenia, anemia, and peripheral neuropathy. Nurses monitor for side effects, ensure adequate hydration and electrolyte replacement, and assess the IV site frequently during administration.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    2K views3 pages

    Drug Study - Cisplatin

    Uploaded by

    Danielle Aglusolos
    Cisplatin is an antineoplastic drug that inhibits DNA synthesis, causing cross-linking of parent DNA strands and death of rapidly replicating cells. It is indicated for metastatic testicular and ovarian carcinoma, advanced bladder cancer, head and neck cancer, cervical cancer, lung cancer, and other tumors. Common side effects include nausea, vomiting, diarrhea, nephrotoxicity, ototoxicity, alopecia, hypocalcemia, hypokalemia, hypomagnesemia, leukopenia, thrombocytopenia, anemia, and peripheral neuropathy. Nurses monitor for side effects, ensure adequate hydration and electrolyte replacement, and assess the IV site frequently during administration.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    You are on page 1of 3

    SIDE EFFECTS AND ADVERSE

    DRUG MECHANISM OF ACTION INDICATION NURSING ACTION


    EFFECTS
    Inhibits DNA synthesis by Metastatic testicular and CNS: SEIZURES, malaise,  Monitor vital signs frequently
    producing cross-linking of ovarian carcinoma. Advanced weakness. 
    during administration. Report
    EENT: ototoxicity, tinnitus.
    parent DNA strands (cell-cycle bladder cancer. Head and
    GENERIC NAME:
     GI: severe nausea, vomiting, significant changes
    cisplatin phase—nonspecific).  neck cancer. Cervical cancer. diarrhea, hepatotoxicity. 
    Therapeutic Effects: Death of Lung cancer. Other tumors. GU: nephrotoxicity, sterility.   Monitor intake and output and
    Derm: alopecia. 
    rapidly replicating cells, specific gravity frequently
    BRAND NAME:
    F and E: hypocalcemia,
    Platinol particularly malignant ones. during therapy.
    hypokalemia, hypomagnesemia.
     Hemat: LEUKOPENIA,
    THROMBOCYTOPENIA, anemia.
     Report discrepancies
    DRUG CLASSIFICATION:
     Local: phlebitis at IV site.  immediately.
    Antineoplastics Metab: hyperuricemia. 
    Neuro: peripheral neuropathy.  Encourage patient to drink
     Misc: anaphylactoid reactions.
    2000– 3000 mL/day to
    CONTRAINDICATION INTERACTIONS
    Hypersensitivity; Orally disintegrating Drug-Drug: risk of nephrotoxicity and promote excretion of uric acid.

    tablets contain aspartame and ototoxicity with other nephrotoxic and


     Assess patency of IV site
    should not be used in patients with ototoxic drugs (aminoglycosides,
    phenylketonuria; loop diuretics).risk of hypokalemia frequently during therapy.

    and hypomagnesemia with loop


     Monitor amount of emesis
    diuretics and amphotericin B.

    Maypphenytoin levels. bone marrow and notify health care

    depression with other antineoplastics professional if emesis

    or radiation therapy. May antibody exceeds guidelines to prevent

    response to live-virus vaccines and dehydration.


    adverse reactions
     Monitor for bone marrow

    depression.

     Assess for bleeding

     Monitor for increased fatigue,

    dyspnea, and orthostatic

    hypotension.

     Monitor for signs of


    anaphylaxis

     Assess patient frequently for

    dizziness, tinnitus, hearing

    loss, loss of coordination, loss

    of taste, or numbness and

    tingling of extremities

    You might also like