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    Dosage Recommendation: Stroke

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    Sara Abd el sattar

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    Dosage Recommendation: Stroke

    Uploaded by

    Sara Abd el sattar
    52 views3 pages

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    Cerebrolysin_Dosage_recommendation.pdf

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    52 views3 pages

    Dosage Recommendation: Stroke

    Uploaded by

    Sara Abd el sattar

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
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    of 3

    STROKE

    TBI

    DEMENTIA

    Dosage Recommendation

    Reconnecting Neurons.
    Empowering for Life.
    Dosage recommendation

    Daily
    Disorder Initiation of treatment Duration of treatment
    dosage

    Stroke 20 - 50 ml as soon as possible 10 - 21 days

    Traumatic brain injury 20 - 50 ml as soon as possible 7 - 30 days

    1 cycle: 5 days weekly/4 weeks


    Vascular dementia 10 - 30 ml as soon as possible
    2-4 cycles per year
    1 cycle: 5 days weekly/4 weeks
    Alzheimer’s disease 10 - 30 ml as soon as possible
    2-4 cycles per year

    Route of administration

    IV injection up to 10ml undiluted inject slowly


    over 3 minutes
    IM injection up to 5ml undiluted inject slowly
    over 3 minutes
    The IV or IM injection has to be administered immediately after opening the ampoule!

    IV infusion 10ml - 50ml diluted to at least 100ml total Infuse within


    volume with Saline, Ringer 15 minutes
    solution or 5% glucose solution
    To guarantee sterility, always use disposable one-way infusion sets and cannulas!
    Start the infusion as quickly as possibe after dilution!
    Cerebrolysin should not be mixed with balanced amino acid solutions, vitamins and
    cardiovascular medicinal products.

    Dilution procedures for IV infusion

    1 2 3 4 5

    Inject
    Extract Discard
    Break Cerebrolysin Infuse
    contents of IV lines after
    ampoule in the Cerebrolysin
    Cerebrolysin use
    diluents

    Flush with sodium chloride solution before & after infusion


    Safe administration – sterility aspects
    Special precautions to guarantee sterility must be taken during dilution and administration of Cerebrolysin:
    • Remove solution from ampoules immediately before use
    • Do not leave an open ampoule on the treatment table
    • Always use only disposable one-way IV infusions sets and cannulas
    • When Cerebrolysin is administered via a long-term IV catheter, the catheter has to be rinsed before and
    after the application with physiological sodium chloride solution
    • Pay special attention to recommended infusion/injection times on previous page

    Conditions for storage


    • Cerebrolysin must be stored at room temperature not exceeding 25°C
    • Do not freeze!
    • Has to be protected from light (in the carton)

    ABBREVIATED PRESCRIBING INFORMATION - Cerebrolysin. Name of the medicinal product: Cerebrolysin - Solution for injection. Qualitative and quantitative
    composition: One ml contains 215.2 mg of Cerebrolysin concentrate in aqueous solution. List of excipients: Sodium hydroxide and water for injection. Thera-
    peutic indications: For treatment of cerebrovascular disorders. Especially in the following indications: Senile dementia of Alzheimer’s type. Vascular dementia.
    Stroke. Craniocerebral trauma (commotio and contusio). Contraindications: Hypersensitivity to one of the components of the drug, epilepsy, severe renal im-
    pairment. Marketing Authorisation Holder: EVER Neuro Pharma GmbH, A-4866 Unterach. Only available on prescription and in pharmacies. More information
    about pharmaceutical form, posology and method of administration, special warnings and precautions for use, interaction with other medicinal products and
    other forms of interaction, fertility, pregnancy and lactation, effects on ability to drive and use machines, undesirable effects, overdose, pharmacodynamics
    properties, pharmacokinetic properties, preclinical safety data, incompatibilities, shelf life, special precautions for storage, nature and contents of the container
    and special precautions for disposal is available in the summary of product characteristics.

    Copyright © 2016 by EVER Neuro Pharma GmbH, Oberburgau 3, 4866 Unterach, Austria. All rights reserved. No part of this brochure may be reproduced in
    any form or by any electronic or mechanical means, including information storage and retrieval systems, without permission in writing from the publisher.
    Cerebrolysin is a registered trademark of EVER Neuro Pharma GmbH, 4866 Unterach, Austria
    CERE/A/05/2016/64

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