CAOP Exam Sample May 2020
CAOP Exam Sample May 2020
CAOP Exam Sample May 2020
The CAOP Examination is 70-questions long and candidates have 2 hours to complete it.
All questions in this sample paper are no longer used in examinations and have been chosen to provide CAOP
candidates with exposure to the format, phrasing and layout of questions.
The questions in this sample paper may not reflect the exact model of the CAOP examination in terms of
accuracy, currency, difficulty, and proportion of subject matter areas covered.
The APC does not guarantee that the questions in this sample paper retains the same accuracy or relevancy,
as was the case at time of question development.
The CAOP exam is a computer-based examination. For information about registration for the examination and
examination syllabus please visit the APC website.
What is the minimum number of dispersible tablets required for the complete 10-day course?
A. 20
B. 16
C. 13
D. 10
E. 8
Q2 How many mL of 90% alcohol, when diluted to 135 mL, produces 60% alcohol?
A. 60 mL
B. 73 mL
C. 79 mL
D. 81 mL
E. 90 mL
Q3 A patient is prescribed clonazepam 0.8 mg per day. A bottle of clonazepam 2.5 mg/mL drops is
provided, and one drop is equal to 0.04 mL.
A. 80 drops
B. 40 drops
C. 16 drops
D. 8 drops
E. 4 drops
Q4 A medicine is provided as a 1 g powder which, when reconstituted with 9.6 mL of water for
injection, provides a solution of 100 mg/mL. The dose of the medicine for a child is 50
mg/kg/day in two divided doses.
A. 1.25 mL
B. 2.5 mL
C. 8.75 mL
D. 12.5 mL
E. 17.5 mL
1
Q5 An 80 kg man is being treated for ventricular fibrillation with lignocaine. The protocol for the
lignocaine infusion (using a 5 mg/mL vial) is:
What volume of lignocaine is required for the initial bolus and the first hour of the infusion?
A. 40 mL
B. 60 mL
C. 60.5 mL
D. 80 mL
E. 4820 mL
Q6 Calculate the total dose of alteplase administered for a 50 kg female based on the following
dose regimen:
Bolus 15 mg
Infusion 0.75 mg/kg over 30 minutes then 0.5 mg/kg over 60 minutes
A. 15 mg
B. 16.25 mg
C. 62.5 mg
D. 52.5 mg
E. 77.5 mg
2
Patient Profile
________________________________________________________________________________
DIAGNOSIS
Presenting Complaint: 1. Community-acquired pneumonia (mild persistent)
2. Pneumonia Severity Index (PSI) = Class 1
MEDICATION RECORD
Date Medication Quantity Directions for use
15/11 Prednisolone 5 mg 60 Take SEVEN tablets
in the morning
5/11 Budesonide 40 microgram / dose One Inhale TWO puffs
Inhaler twice a day
5/10 Beclometasone 100 microgram / dose One Inhale TWO puffs
Inhaler twice a day
5/10 Salbutamol 100 microgram / dose One Inhale TWO puffs
Inhaler every 4 hours
PHARMACIST NOTES
Date Comment
5/10 Continuing therapy. Confirmed non-smoker.
3
Q8 What is the MOST appropriate treatment for Tim for community acquired pneumonia?
A. Roxithromycin
B. Clarithromycin
C. Gentamicin
D. Trimethoprin with sulfamethoxazole
Q9 Following resolution of his pneumonia, Tim still does not have good control of his asthma.
What is the MOST appropriate treatment option to help him get control of his asthma?
Q10 Tim is commencing budesonide, what other change(s) should be made to his medication?
4
Patient Profile
________________________________________________________________________________
DIAGNOSIS
Presenting Complaint: 1. Angina
MEDICATION RECORD
Date Medication Quantity Directions for use
14/11 Glyceryl trinitrate 600 microgram 100 tablets Take as directed by your
doctor for angina
14/11 Amlodipine 5 mg 30 tablets Take ONE in the morning
30/10 Simvastatin 20 mg 30 tablets Take ONE in the morning
28/10 Fluoxetine 20 mg 28 tablets Take ONE in the morning
3/10 Aspirin 100 mg 112 tablets Take ONE in the morning
PHARMACIST NOTES
Date Comment
3/10 Ralph has indicated he is experiencing nocturnal chest pain.
5
Q11 Ralph presents to you with a prescription for glyceryl trinitrate patches 10 mg / 24hr.
What is the MOST appropriate regimen for Ralph for the use and application of glyceryl
trinitrate patches?
Q12 In an acute angina attack, which ONE of the following is the MOST appropriate way to use
glyceryl trinitrate sublingual tablets?
A. Dissolve 1 tablet under the tongue and wait 5 minutes. Call an ambulance if pain persists
B. Dissolve 1/2 to 1 tablet under the tongue and repeat if pain persists. Call an ambulance if 2
repeats over 10 minutes do not relieve pain
C.Dissolve 1/2 to 1 tablet under the tongue. Call an ambulance if pain is not relieved after 15
minutes
D.Dissolve 1 tablet under the tongue and repeat every 3 minutes if pain persists. Call an
ambulance if 4 repeats over 15 minutes do not relieve pain
Q13 Following the initiation of therapy with fluoxetine in this patient, the maximal anti-depressant
effects is MOST likely achieved after:
A. 1 week
B. 10 days
C. 4 weeks
D. 12 weeks
Q14 Along with swelling of the ankles, which ONE of the following side effects is MOST commonly
observed with amlodipine?
A. Cough
B. Sedation
C. Chest pain
D. Dizziness
6
Q15 Which ONE of the following statements about a Permethrin 5% cream is MOST appropriate?
Permethrin 5% cream when used for scabies:
Q16 A female customer has recently given birth and is breastfeeding her baby. Her doctor has
prescribed the progesterone only pill and as she has not used this type of pill before, she has a
few questions.
Which ONE of the following counselling points would be MOST appropriate for her?
Q17 A 45-year-old male patient, stabilised on warfarin at an International Normalised Ratio (INR) of
2.4, has decided to go on a vegetarian diet.
Which ONE of the following is the MOST appropriate advice to give him about his diet?
7
Q18 With regard to injector pens, when used for the basal-bolus regimen in the control of insulin
dependent diabetes which of the following is INCORRECT?
Injector pens give
Q19 The metalwork teacher from the local high school comes into your pharmacy with a student
complaining of a red and painful eye. Upon examination you can see a small piece of metal
lodged in the surface of his eye.
Which ONE of the following is the MOST appropriate action to take?
A. Irrigate the eye under a stream of cool tap water for at least 10 minutes
B. Recommend the use of anti-inflammatory eye drops, with the instruction to visit the doctor if
the inflammation persists after 24 hours
C.Lie the student down and tell him to keep still, whilst you remove the metal with a clean pair
of forceps
D.Close the eye, cover it with a bandage or sterile pad, tell him to keep his head still and
arrange for transport to the nearest hospital
Q20 Which ONE of the following counselling points is MOST appropriate for alendronate?
Q21 George is an obese patient, with mature onset Type 2 diabetes. Attempts at treating the
diabetes with diet modification have not worked. The MOST appropriate medicine
recommendation is
A. insulin
B. a sulfonylurea
C. a biguanide
D. an alpha glucosidase inhibitor
8
Q22 A vial of insulin currently in use may be stored at up to 25°C without loss of potency for what
length of time?
A. One hour
B. One day
C. Two weeks
D. Four weeks
Q23 Agranulocytosis is MOST commonly associated with which ONE of the following
antipsychotics?
A. Olanzapine
B. Risperidone
C. Haloperidol
D. Clozapine
Q24 What is the LEAST appropriate SSRI for the management of depression during pregnancy?
A. Citalopram
B. Paroxetine
C. Sertraline
D. Fluoxetine
9
Patient Profile
________________________________________________________________________________
DIAGNOSIS
Presenting Complaint: 1. Pregnant with second child (38 weeks gestation)
MEDICATION RECORD
Date Medication Quantity Directions for use
1/09 Paroxetine 20 mg 30 Take ONE daily
PHARMACIST NOTES
Date Comment
Nil
10
Q25 Due to complications of mastitis with her previous child, Cassandra decides not to breastfeed
this new baby.
Which ONE of the following is the MOST appropriate for the suppression of lactation?
A. Metoclopramide
B. Domperidone
C. Bromocriptine
D. Cabergoline
Q26 If Cassandra did develop mastitis, which is the MOST appropriate antibiotic for treatment?
A. Flucloxacillin
B. Clindamycin
C. Ciprofloxacin
D. Erythromycin
A. Pseudomonas aeruginosa
B. Escherichia coli
C. Streptococcus pyogenes
D. Staphylococcus aureus
11
Q28 Which ONE of the following statements regarding the use of zolpidem is CORRECT?
Zolpidem:
A. Is a benzodiazepine
B. Has a long duration of action
C. Is recommended for use in children
D. Should be used with caution in patients with hepatic impairment
Q29 Mrs Jones, a 35-year-old woman, is a regular patient at your pharmacy. She reports pain in her
Achilles tendon that appeared two days ago. She says that she had gastroenteritis on holiday in
Thailand for which she was prescribed:
Metronidazole 400 mg three times a day
Ciprofloxacin 500 mg twice a day
Ranitidine 150 mg twice a day
Paracetamol/aspirin/caffeine 250/250/65 mg three times a day
Mebeverine 135 mg twice a day
Capsules containing lactobacillus
A. Metronidazole
B. Ciprofloxacin
C. Ranitidine
D. Mebeverine
12
Q30 Which ONE of the following electrolytes can be affected by high dose inhaled salbutamol?
A. Sodium
B. Potassium
C. Bicarbonate
D. Magnesium
Q31 Which ONE of the following beta-blockers has been proven to reduce both morbidity and
mortality in patients with left ventricular systolic heart failure?
A. Atenolol
B. Propranolol
C. Carvedilol
D. Sotalol
13
Patient Profile
________________________________________________________________________________
DIAGNOSIS
Presenting Complaint: 1. Advanced breast cancer
2. Bone metastases
Medical History:
MEDICATION RECORD
Date Medication Quantity Directions for use
30/9 Ondansetron 8 mg 10 Take ONE every 8 hours for
3 days
17/9 Dexamethasone 20 mg (oral) stat
1/9 Doxorubicin 75 mg / m2 IV every 3 weeks
PHARMACIST NOTES
Date Comment
Nil
14
Q32 Judith presents with cardiac failure characterised by shortness of breath and peripheral
oedema.
Which ONE of the following actions is MOST appropriate regarding the doxorubicin dosing?
Q33 The MOST likely indication for dexamethasone in Judith's medication profile is as what type of
agent?
A. Analgesic
B. Anti-emetic
C. Anti-cancer
D. Immunosuppressant
15
Q35 Which ONE of the following combinations of medications is LEAST likely to cause serotonin
syndrome?
Q37 Which ONE of the following therapies is NOT appropriate for an 80-year-old woman who
presents with post herpetic neuralgia?
16
Q39 Which ONE of the following medications is strongly associated with constipation?
A. Felodipine
B. Amlodipine
C. Nifedipine
D. Verapamil
Q40 Which ONE of the following medicines MOST likely needs a dose adjustment in renal
dysfunction?
A. Prednisolone
B. Allopurinol
C. Indometacin
D. Fluoxetine
Q41 When converting a patient from standard levodopa/carbidopa formulations to controlled release
formulations, which of the following is INCORRECT?
Q42 Which ONE of the following medications is LEAST likely to cause gastric upsets?
A. Enalapril
B. Sulindac
C. Prednisolone
D. Fluoxetine
17
Q43 Which ONE of the following side effects is MOST likely to occur with high doses of
hydrochlorothiazide?
A. Photosensitivity
B. Nightmares
C.Urinary hesitancy
D.Metabolic disturbances
Q44 Which ONE of the following medications may be taken at night to maximize its concentration in
the blood and/or urine?
A. Trimethoprim
B. Atorvastatin
C. Mirtazipine
D. Perindopril
Q45 Phytomenadione (vitamin K) is used for which ONE of the following reasons?
18
Patient Profile
________________________________________________________________________________
DIAGNOSIS
Presenting Complaint: 1. Worsening acne
MEDICATION RECORD
Date Medication Quantity Directions for use
20/12 Isotretinoin 10 mg 60 Take ONE in the morning;
Take TWO at night
20/12 Ethinylestradiol / levonorgesterol 112 Take ONE daily
20/12 Doxycycline 100 mg 21 Take ONE daily
20/12 Vitamin B complex tablets 90 Take ONE daily
PHARMACIST NOTES
Date Comment
20/2 Jane is distressed because her is acne not improving.
Jane wants to try benzoyl peroxide cream in addition to isotretinoin.
Jane discloses she regularly fails to the take the evening dose of isotretinoin.
19
Q46 What is the MOST appropriate advice to give Jane about benzoyl peroxide cream?
Q47 Which ONE of the following statements is the MOST appropriate with regard to improving
Jane's compliance with isotretinoin therapy?
A. Don't worry about the missed doses because the medicine is so potent
B. Recommend a once daily dosage regimen in the morning
C. Recommend she takes 3 capsules the morning following the missed dose
D. Recommend she take 2 capsules in the morning and 1 at night
Q48 Which ONE of the following adverse events is the MOST common during isotretinoin therapy?
20
Q49 A customer who had a kidney transplant 6 months ago is taking ciclosporin regularly to
suppress rejection. He has recently acquired a fungal infection under his toenails. His doctor
phones to ask your advice on treatment of onychomycosis.
A. Fluconazole capsules
B. Terbinafine tablets
C. Griseofulvin tablets
D. Clotrimazole lotion
Q50 Which ONE of the following groups of patients are MOST at risk of tendon damage if treated
with quinolones?
A. Patients on corticosteroids
B. Patients between 20 - 50 years old
C. Patients who have had a CABG
D. Patients with heart failure
Q51 Which ONE of the following statements regarding the use of paracetamol for osteoarthritic
pain is LEAST appropriate?
A. Paracetamol is the treatment of choice for mild to moderate, persistent osteoarthritic pain
B. Analgesic effects of paracetamol begin approximately 30 minutes after oral administration
C. Lack of pain control with paracetamol is frequently due to inadequate dosing of
paracetamol
D. Strong evidence suggests that the risk of hepatotoxicity from paracetamol is increased in
patients with chronic liver failure
A. Stomatitis
B. Hypercalcaemia
C. Osteonecrosis of the jaw
D. Oesophagitis
21
Q53 Primary hyperaldosteronism results in which ONE of the following health outcomes?
22
Patient Profile
________________________________________________________________________________
DIAGNOSIS
Presenting Complaint: 1. Severe epigastric pain
2. Persistent and unresolved nausea
MEDICATION RECORD
Date Medication Quantity Directions for use
3/7 Aspirin 300 mg 100 Take HALF in the
morning
3/7 Calcitriol 0.25 microgram 100 Take ONE twice a day
3/7 Calcium carbonate 600 mg 60 Take ONE twice a day
3/7 Galantamine 16 mg 28 Take ONE daily
3/7 Metoclopramide 10 mg 25 Take ONE three times
a day as needed
3/7 Pantoprazole 40 mg 30 Take ONE daily
3/7 Paracetamol 500 mg 200 Take TWO in the
morning
PHARMACIST NOTES
Date Comment
3/7 Medications are current and ongoing.
37/ Recommended doctor review patient’s medicines in light of her exacerbation of epigastric
pain and nausea.
3/7 Galantamine 8 mg ceased.
23
Q54 An allergy to which ONE of the following requires that further considerations are met in excess
of those normally in place for a person wishing to have an influenza vaccination?
A. Peanuts
B. Sulfates
C. Oysters
D. Eggs
Q55 Which ONE of the following treatment options would be the MOST appropriate to relieve
Audrey's nausea/vomiting?
Q56 Which ONE of the following tests may be considered to investigate her continuing gastric
discomfort?
A. Colonoscopy
B. B12/Folate
C. Urea breath test
D. Bronchoscopy
Q57 Which ONE of the following medications is LEAST suitable to manage Audrey's depression?
A. Sertraline
B. Mirtazapine
C. Doxepin
D. Moclobemide
24
Q58 Which ONE of the following medicines is LEAST likely to be contributing to Audrey's
nausea/vomiting?
A. Galantamine
B. Calcitriol
C. Aspirin
D. Calcium carbonate
25
Q59 Which ONE of the following medications is LEAST likely to increase the risk of lithium toxicity?
A. Diclofenac
B. Amiloride
C. Frusemide
D. Enalapril
Q60 Which ONE of the following Gram-negative bacteria is the primary cause of urinary tract
infections?
A. Escherichia coli
B. Helicobacter pylori
C. Shigella dysenteriae
D. Pseudomonas aeruginosa
Q61 When counselling on the use of an azole antifungal cream, you would advise all of the
following EXCEPT which ONE of the following?
Q62 In regards to colic, which ONE of the following practices is NOT recommended?
26
Q63 A person has a recent soft tissue injury and asks for your advice.
27
PATIENT PROFILE
Diagnosis
Presenting Complaint: 1. Hyperglycaemia
Medical History:
Medication Record
Date Medication Quantity Directions for use
Pharmacist's Notes
Date Comment
Nil
28
Q64 Dane has never had an attack of gout, but his urate level is elevated. Which ONE of
the following is the MOST appropriate action to take?
Q65 Dane has a number of risk factors for cardiovascular disease. Which ONE of the
following would be an additional risk factor?
Q66 If Dane was started on metformin, which ONE of the following statements is
CORRECT in regard to this medication?
Metformin:
A Can be used in patients with severe renal impairment with careful monitoring
B Can be used in renal impairment but not below a CrCl of 60ml/minute
C Can be used and its dose is not dictated by the state of the renal function
D Can cause renal impairment and it should be ceased until renal impairment
has resolved
Q67 Which ONE of the following is the BEST indicator of Dane's ongoing blood glucose
control?
29
PATIENT PROFILE
Diagnosis
Presenting Complaint: 1. Pain and fever
Medical History: 1. Otitis media
Medication Record
Date Medication Quantity Directions
for use
Pharmacist's Notes
Date Comment
17/3 Thomas has been experiencing localised pain in the ear for 2 days, which has not
resolved with regular paracetamol use.
30
Q68 If Thomas' mother is using paracetamol mixture 100 mg/mL, what directions are
MOST appropriate for Thomas?
Q69 After five days of treatment, Thomas develops severe diarrhoea with the antibiotics
that he is using. Which ONE of the following is the MOST appropriate treatment?
Q70 Which ONE of the following organisms is MOST likely to cause otitis media?
A Staphylococcus aureus
B Escherichia coli
C Streptococcus pneumonie
D Mycoplasma pneumoniae
E Aspergillus
31
Australian Pharmacy Council Ltd
CAOP
Sample 2: Answers
Question Correct Answer
1 C
2 E
3 D
4 C
5 D
6 E
7 A
8 B
9 A
10 A
11 D
12 B
13 D
14 D
15 B
16 D
17 B
18 B
19 D
20 A
21 C
22 D
23 D
24 B
25 D
26 B
27 D
28 D
29 B
40 B
31 C
32 A
33 B
34 B
35 D
36 D
37 D
38 A
39 D
32
40 B
41 A
42 A
43 D
44 A
45 D
46 A
47 B
48 B
49 B
50 A
51 D
52 D
53 A
54 D
55 C
56 C
57 C
58 D
59 B
60 A
61 A
62 D
63 D
64 D
65 C
66 A
67 B
68 B
69 A
70 C
33