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Pathophysiology

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Pathophysiology

Predisposing factors Precipitating factors

Age, Gender, Family High Blood Pressure Diet, Obesity & alcohol
History

Susceptible for having extreme pressure ↑salt, ↑Na,


↑fats
diseases

increase risk for ↑BP dilatation of small vessels leads to formation of


plaque
vessels repair itself

↑ risk for TIA narrowing of vessel


(transient ischemic attack) thickening of vessels lumen

tortuosity of endothelium turbulent blood flow

formation of atherosclerosis plaque flow

↓ blood flow activation of clotting


cascade
ischemic infarct

increase pressure

compression of brain tissue

spasm of adjacent vessels

rupture of vessels

intracerebral hemmorhage in the brain parenchyma


Diabetes Mellitus Cigarrette Smoking

↑low density lipids & ↓ O2 concentration


↓high density lipids ↑ carbon monoxide in the blood
supply
Leads to constriction of vessels
Fomation of plaques
Increases blood pressure
Narrowing of vessels

Progression of macrovascular complication

blockage formation on vessels of the brain

ischemia on affected area

increasing pressure

compression of brain tissue

spasm of adjacent vessels

rupture of vessels

intracerebral hemmorhage in the brain parenchyma

Signs and symptoms

• Sudden Impaired speech


• Sudden Inability to see in one eye or double vision
• Sudden Inability to walk
• Sudden Paralysis on one side of the body
• Sudden Numbness or tingling
If treated: if untreated:

Diagnosis: increase intracranial pressure


computed tomography
MRI massive compression of tissues

Medication: progression of hemmorrage


anti-hypertensive
-to control hypertension decrease O2 supply in the brain
Diuretics
-to decrease icp death
antidiabetic agents
-to reduce effects of diabetes

Complication would be alleviated

Lifestyle changes

rehabilitation

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