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    Schematic Pathophy Dka

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    Maria Francheska Osi
    This document provides a diagram outlining the pathophysiology of diabetic ketoacidosis. It shows that a lack of insulin leads to increased breakdown of fats which produces ketone bodies, increasing blood glucose levels and causing a metabolic acidosis. If left untreated, the acidosis and high glucose levels can cause dehydration, electrolyte imbalances, and neurological symptoms such as weakness and confusion. The key features of diabetic ketoacidosis include hyperglycemia, glucosuria, ketonuria, and a fruity odor on the breath from ketone production and exhalation.

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    Schematic Pathophy Dka

    Uploaded by

    Maria Francheska Osi
    71 views2 pages
    This document provides a diagram outlining the pathophysiology of diabetic ketoacidosis. It shows that a lack of insulin leads to increased breakdown of fats which produces ketone bodies, increasing blood glucose levels and causing a metabolic acidosis. If left untreated, the acidosis and high glucose levels can cause dehydration, electrolyte imbalances, and neurological symptoms such as weakness and confusion. The key features of diabetic ketoacidosis include hyperglycemia, glucosuria, ketonuria, and a fruity odor on the breath from ketone production and exhalation.

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    SCHEMATIC PATHOPHY DKA

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    This document provides a diagram outlining the pathophysiology of diabetic ketoacidosis. It shows that a lack of insulin leads to increased breakdown of fats which produces ketone bodies, increasing blood glucose levels and causing a metabolic acidosis. If left untreated, the acidosis and high glucose levels can cause dehydration, electrolyte imbalances, and neurological symptoms such as weakness and confusion. The key features of diabetic ketoacidosis include hyperglycemia, glucosuria, ketonuria, and a fruity odor on the breath from ketone production and exhalation.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    71 views2 pages

    Schematic Pathophy Dka

    Uploaded by

    Maria Francheska Osi
    This document provides a diagram outlining the pathophysiology of diabetic ketoacidosis. It shows that a lack of insulin leads to increased breakdown of fats which produces ketone bodies, increasing blood glucose levels and causing a metabolic acidosis. If left untreated, the acidosis and high glucose levels can cause dehydration, electrolyte imbalances, and neurological symptoms such as weakness and confusion. The key features of diabetic ketoacidosis include hyperglycemia, glucosuria, ketonuria, and a fruity odor on the breath from ketone production and exhalation.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    of 2

    SUMAGUE, Maria Francheska O.

    BSN 4
    DIABETIC KETOACIDOSIS

    Absolute Insulin
    Deficit

    Lack of insulin to Glucose remains in


    suppress lipolysis blood not being
    allows the body to utilized by muscle
    start producing and fat cells
    energy from
    Hypothalamic cells
    triglycerides
    sense low
    intracellular
    glucose, triggering Decrease of
    hunger glucose in cells
    Release of free fatty
    increase the
    acids from adipose
    release of
    tissue
    glucagon,
    Polyphagia epinephrine,
    cortisol and growth
    hormone
    Hydrolysis of free
    fatty acids in the
    liver

    Body tries to
    increase blood
    glucose to increase
    cell glucose
    absorption
    Decreased
    protein
    synthesis
    Increased
    proteolysis in Increase
    muscle gluconeogenesis
    and increased
    glycogenolysis in
    liver

    Hyperglycemia

    Less than 12 mmol/L


    and increased
    glucose filtration,
    increased urine
    Glucosuria

    Glucose in filtrate
    promotes osmotic
    diuresis

    Polyuria
    Alters total
    Electrolyte imbalance body water &
    ion osmosis
    Severe Dehydration

    Polydipsia If pt alert & H2O


    is accessible

    Decreased ECF
    volume concentrates
    Metabolic Acidosis
    ketone bodies,
    exacerbates acidosis

    Disrupts enteric Blowing off CO2 Breathing Disruption of


    nervous system, to try to offset off ketones electrical signaling in
    decreased emptying acidosis brain, spinal cord
    of ileus and nerves

    Ketone breath
    Kussmaul
    (fruity odor)
    Abdominal Nausea, respiration
    Weakness/
    pain Vomiting Confusion

    Reference:
    Cheever, K. H., & Hinkle, J. L. (2018). Brunner & Suddarth's textbook of medical-surgical nursing.
    Philadelphia: Wolters Kluwer.

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