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Gochi Notes: Immuno-Allergy Part Vi Lecturer: Dra. Eva Dizon

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GoChi Notes

Immuno-Allergy Part VI
Lecturer: Dra. Eva Dizon Allergy – Urticaria/Agioedema

Urticaria
Atopic Dermatitis (AD)
transient, pruritic, erythematous, raised
Major Features wheals, with flat tops and edema that may become
tense and painful
Pruritus The lesions may coelesce and form
Eczema- facial, EXTENSOR(infants and polycyclic, serpiginous, or annular lesions
children), Individual lesions usually 20 min to 3 hr
FLEXURAL (adolescent) Rarely more than 24 hr
Chronicity Family history Recurrent

Treatment Angioedema

Xerosis - Wet dressings Involves the deeper subcutaneous tissues


Corticosteroids Eyelids, lips, tongue, genitals, and dorsun of
Calcineurin inhibitors the hands or feet
Antihistamine
Tar Allergy
Cyclosporine
Phototherapy Insect allergy
Ocular allergy
Urticaria and angioedema
Predictive Factors of a poor prognosis:
<6 weeks - acute
>6 weeks, 2x a week- Chronic
Widespread AD in childhood
FLAGGRIN gene null mutations
Allergy- Urticaria
Concomitant allergic rhinitis and asthma
Physical- pressure, stroking, cold, heat,
Family history of AD in parents or siblings
vibration, light
Early age at onset of AD
Being an ONLY Child
Very high serum IgE levels
Cholinergic urticaria- sweating, hot
showers, after exercise
Prevention Dernatographism - striking
Pressure urticaria - 4-6 hrs, after sitting
Breastfeeding tight pants, socks, walking
Hypoallergenic formula Aquagenic urticaria
Probiotics Solar urticaria - 1-3min
Chronic idiopathic urticaria - UNKNOWN
origin, NOT ALLERGIC IN ORIGIN

GoChi Notes Page 1


GoChi Notes

Dermatographia

It means if you write on the skin, then it will


show what you have written.

Allergic - Urticaria

Treatment

Antihistamine- H1 blocker
Cimetidine, Ranitidine, Famotidine-H2
Corticosteroid
Epinephrine 1:1000, 0.01 ml/k (0.3 ml max) IM
Removal or avoidance of the triggers

By: KTRC

GoChi Notes Page 2

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