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Module 6 Lesson 6.1

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Name: Zemiah Marie Puerto Course and Year: BSED 4

Subject: Fundamentals of Genetics Schedule: Tuesday 07:30-09:30

Module: 6 Lesson 6.1: DNA Structure

Learning Tasks/Activities:

In this activity, you will build a 3D model of the DNA and use the model to explore key
structural features of the DNA double helix. Use common craft supplies or recycled
materials you can find at home to represent each structure of the DNA and label it.
Sample photos are posted below. Attach two photographs of you making the 3D model
as well as the final DNA structure

Assessment:
Read each statement or question below and identify what is asked.

1. What are the four pairs of DNA bases that form in the double helix?
Adenine (A), Thymine (T), Cytosine (C) & Guanine (G)

2. What holds one strand against the other in the double helix?
Hydrogen bonds
3. Which DNA double helix do you think would be harder to separate into two strands:
DNA composed predominantly of AT base pairs, or of GC base pairs? Why?
The DNA composed of Guanine & Cytosine base pairs will be harder to
separate because of the three bonds of hydrogen that provide the structure with
greater stability.

4. Which bases are purines? Pyrimidines?


Adenine and Guanine bases are classified as purines while Cytosine and
Thymine are pyrimidines.

5. What holds one strand against the other in the double helix?
Hydrogen bonds

6. How many strands make up a DNA double helix?


Two strands

7. DNA looks like a “twisted ladder”. If the “rungs” of the ladder are made up of
nitrogenous bases, what are the handrails or backbone of the ladder made up of?
Sugars and Phosphates

8. How can A distinguish T from C?


Adenine can distinguish Thymine from Cytosine on the basis of the number and
direction of hydrogen bonds T or C can form with A.

9. How do cells make accurate copies of DNA?


When a cell divides, it replicates its DNA by splitting apart double-stranded DNA
and makes new copies along the single strands of the original DNA. The original DNA
now becomes a part of a double-strand containing new DNA, randomly splits between
the two dividing cells. By always keeping the original strands, it ensures that it
maintains the original information.

10. What is a "strand" of DNA?


DNA strand consists of nucleotides that are linked into chains held together by
strong chemical bonds, with the phosphate and sugar groups alternating.

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