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    Pharmacologic Class: Therapeutic Class: Atypical: Dibenzothiazepine Derivative Antipsychotic

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    Bianca Nicole Gacad Fernandez
    Quetiapine fumarate (Seroquel, Seroquel XR) is an atypical antipsychotic used to treat schizophrenia, bipolar disorder, and major depressive episodes associated with bipolar disorder. It works by increasing acetylcholine levels in the brain. Common side effects include headache, drowsiness, dizziness, constipation, and dry mouth. Rare but serious side effects include neuroleptic malignant syndrome and prolonged QT interval. Nurses monitor patients for side effects and adverse drug reactions, provide education on proper administration, and assess for signs of tardive dyskinesia or suicidal ideation.

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    Pharmacologic Class: Therapeutic Class: Atypical: Dibenzothiazepine Derivative Antipsychotic

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    Bianca Nicole Gacad Fernandez
    689 views2 pages
    Quetiapine fumarate (Seroquel, Seroquel XR) is an atypical antipsychotic used to treat schizophrenia, bipolar disorder, and major depressive episodes associated with bipolar disorder. It works by increasing acetylcholine levels in the brain. Common side effects include headache, drowsiness, dizziness, constipation, and dry mouth. Rare but serious side effects include neuroleptic malignant syndrome and prolonged QT interval. Nurses monitor patients for side effects and adverse drug reactions, provide education on proper administration, and assess for signs of tardive dyskinesia or suicidal ideation.

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    quetiapine fumarate

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    Quetiapine fumarate (Seroquel, Seroquel XR) is an atypical antipsychotic used to treat schizophrenia, bipolar disorder, and major depressive episodes associated with bipolar disorder. It works by increasing acetylcholine levels in the brain. Common side effects include headache, drowsiness, dizziness, constipation, and dry mouth. Rare but serious side effects include neuroleptic malignant syndrome and prolonged QT interval. Nurses monitor patients for side effects and adverse drug reactions, provide education on proper administration, and assess for signs of tardive dyskinesia or suicidal ideation.

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    © All Rights Reserved
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    Download as docx, pdf, or txt
    689 views2 pages

    Pharmacologic Class: Therapeutic Class: Atypical: Dibenzothiazepine Derivative Antipsychotic

    Uploaded by

    Bianca Nicole Gacad Fernandez
    Quetiapine fumarate (Seroquel, Seroquel XR) is an atypical antipsychotic used to treat schizophrenia, bipolar disorder, and major depressive episodes associated with bipolar disorder. It works by increasing acetylcholine levels in the brain. Common side effects include headache, drowsiness, dizziness, constipation, and dry mouth. Rare but serious side effects include neuroleptic malignant syndrome and prolonged QT interval. Nurses monitor patients for side effects and adverse drug reactions, provide education on proper administration, and assess for signs of tardive dyskinesia or suicidal ideation.

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    Fernandez, Bianca Nicole G.

    February 22-24, 2020


    BSN 3B-2a CI: Ma’am Ruth Abigail Valdez
    Generic Name / Brand Name Mode of Action Side effects and Adverse Reaction Nursing Responsibility
    Drug Classification
    Generic Name May slow the decline of cognitive Side Effects Administration
    function in patients with Alzheimer’s  Monitor fasting blood lipids
    quetiapine fumarate Frequent (19%–10%): Headache, before treatment.
    disease by increasing acetylcholine
    drowsiness, dizziness.  Give immediate-release tablets
    Brand Name concentration at cholinergic
    transmission sites. This action Occasional (9%–3%): Constipation, with or without food; give
    Seroquel, Seroquel XR prolongs and exaggerates the effects extended-release tablets without
    orthostatic hypotension, tachycardia,
    of acetylcholine that are otherwise food or with a light meal.
    Drug Classification dry mouth, dyspepsia, rash, asthenia,
    blocked by toxic levels of  Don’t confuse Seroquel with
    abdominal pain, rhinitis.
    Pharmacologic class: Serzon (an antidepressant).
    anticholinergics.
    Dibenzothiazepine derivative Rare (2%): Back pain, fever, weight
    Uses gain.Adverse reactions Patient monitoring
    Therapeutic class: Atypical  Monitor neurologic status,
    antipsychotic Treatment of schizophrenia. CNS: dizziness, sedation, cognitive especially for signs and
    Treatment of acute manic episodes impairment, extrapyramidal symptoms of tardive dyskinesia,
    associated with bipolar disorder symptoms, suicidal ideation, or neuroleptic
    (alone or in combination with lithium tardive dyskinesia, neuroleptic malignant syndrome.
    or valproate). Maintenance treatment malignant syndrome, seizures,  Be aware that patient should
    of bipolar disorder as an adjunct to suicide undergo lens examination when
    lithium or valproic acid. Treatment of CV: tachycardia, palpitations, starting treatment and at 6-month
    acute depressive episodes associated intervals during long-term
    peripheral edema, orthostatic
    with bipolar disorder. treatment.
    hypotension, hypertension, QT-
     Monitor blood pressure for
    interval prolongation
    orthostatic hypotension.
    EENT: cataracts, ear pain, rhinitis,  Monitor patient closely for
    pharyngitis prolonged QT interval.
    GI: constipation, dyspepsia, dry  Monitor fasting blood lipids
    mouth, anorexia periodicall during treatment.
    Hematologic: leukopenia
    Metabolic: hypothyroidism Patient teaching
    Respiratory: cough, dyspnea  Tell patient to take immediate-
    Skin: diaphoresis release tablets with or without
    Other: weight gain, flulike food and to take extended-release
    symptoms, acute withdrawal form preferably in the evening,
    symptoms with abrupt cessation swallowed whole, without food or
    with a light meal.
     Instruct patient not to crush,
    Fernandez, Bianca Nicole G. February 22-24, 2020
    BSN 3B-2a CI: Ma’am Ruth Abigail Valdez
    break, or chew extended-release
    tablets.
     Teach patient to recognize and
    immediately report signs and
    symptoms of neuroleptic
    malignant syndrome (such as high
    fever, sweating, unstable blood
    pressure, stupor, muscle rigidity,
    changes in mood or behavior and
    tardive dyskinesia) and prolonged
    QT interval.

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