O HN

C OH O

CH 2 N
N N
H H O

NH
H

H
1210 O
NH HN
H

1180 C O
O
H NH HN
O 1210

NH 2 CH C OH O H
NH N
CH 2
O

2-amino-3-(1H -inden-1-yl)propanoic acid

O H
 O
- O
-

C C

-O O O O -
OH
CH3

O O
H +
CH3 C O H + O H H 3C C O
-
+ H O H

H H H H

HO
Ekstraksi Soxclhet Destilasi Fraksinasi
Destilasi Sederhana
 H ‡

H  H
- H F
C Cl 
H O  F F
H O HC Cl 
H
S
H

F F
F

Li + FH Li- + F-
H
C
CH2

H
CH 3

OH
(E)-6,7-dimethyldeca-3,9-dien-1-yne
O
H3 CO

(S)-2-(6-methoxynaphthalen-2-yl)propanoic acid
 O

H
H OH HN 2 C C O

H
H
CH2

H H

O
O
N
O

HN
NH
N

H
H
H OH
O HO
O NH 2

OH
HO H
H
NH2

4-methylcyclohexyl 4-(5-(6-(3,5-bis(aminomethyl)-2,4,6-triethylbenzylamino)-2-(prop-2-ynyl)heptyl)-2-(((2R,3R,5R)-3-hydroxy-5-(4-((2R)-2-
hydroxy-2-((2S,3R,5S)-3,4,5-trihydroxytetrahydrofuran-2-yl)ethoxy)-2-oxopyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methoxyamino)phenyl)-2-
diazenylbutanoate
 This side open to This side shielded
attack f rom attack
-
D D Br
D B B
B -
H2O + +
C Br H2O C Br H2O C

A A A
Ion Pair Free carbocation

D D D
B B B
HO C HO C + C OH

A A A
Inversion Racemization

Triphospate group

O- O- O-
H3 C CH3
S Nucleophile
O P O P O P OH

O
-C O S CH2 O O Adenine O
(H3 C) 2S O
+ O S(CH 3)2 2 +
Na CH3 H O H
(H3 C) 2S O O S(CH 3)2
O NH3 +
H OH
S
Methionine OH OH

H 3C
CH3 ATP