SAFETY DATA SHEET

SECTION 1: PRODUCT IDENTIFICATION

PRODUCT NAME CHONDROITIN SULFATE SODIUM, USP (Bovine)

PRODUCT CODE 0890
SUPPLIER MEDISCA Inc.
Tel.: 1.800.932.1039 | Fax.: 1.855.850.5855
661 Route 3, Unit C, Plattsburgh, NY, 12901
3955 W. Mesa Vista Ave., Unit A-10, Las Vegas, NV, 89118
6641 N. Belt Line Road, Suite 130, Irving, TX, 75063
MEDISCA Pharmaceutique Inc.
Tel.: 1.800.665.6334 | Fax.: 514.338.1693
4509 Rue Dobrin, St. Laurent, QC, H4R 2L8
21300 Gordon Way, Unit 153/158, Richmond, BC V6W 1M2
MEDISCA Australia PTY LTD
Tel.: 1.300.786.392 | Fax.: 61.2.9700.9047
Unit 7, Heritage Business Park
5-9 Ricketty Street, Mascot, NSW 2020
EMERGENCY PHONE CHEMTREC Day or Night Within USA and Canada: 1-800-424-9300
NSW Poisons Information Centre: 131 126
National Chemical Emergency Centre 44(0)1235239670
USES Supplement

SECTION 2: HAZARDS IDENTIFICATION

GHS CLASSIFICATION Eye Irritation (Category 2B)

PICTOGRAM Not Applicable
SIGNAL WORD Warning
HAZARD STATEMENT(S) Causes eye irritation.
ADVERSE PHYSIOCHEMICAL, HUMAN Not applicable
HEALTH AND ENVIRONMENTAL
EFFECTS
PRECAUTIONARY STATEMENT(S) Prevention Wash thoroughly after handling.
Response IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if
present and easy to do. Continue rinsing.
If eye irritation persists: Get medical advice/attention.
Storage Not applicable
Disposal Not applicable
HMIS CLASSIFICATION Health Hazard 1 Flammability 0

Reactivity 0 Personal Protection A

SECTION 3: COMPOSITION/INFORMATION ON INGREDIENTS

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CHEMICAL NAME Chondroitin Sulfate Sodium

BOTANICAL NAME Not applicable
SYNONYM Chondroitin, hydrogen sulfate, sodium salt
CHEMICAL FORMULA (C₁₄H₁₉NO₁₄SNa₂)n
CAS NUMBER 9082-07-9
ALTERNATE CAS NUMBER Not applicable
MOLECULAR WEIGHT Not applicable
COMPOSITION CHEMICAL NAME CAS NUMBER EC NUMBER % BY WEIGHT
CHONDROITIN SULFATE SODIUM 9082-07-9 618-658-8 100
There are no additional ingredients present which, within the current knowledge of the supplier and in the
concentrations applicable, are classified as health hazards and hence require reporting in this section.
NOTES Chemical family: Sulfated linear mucopolysaccharide.

SECTION 4: FIRST-AID MEASURES

IN CASE OF EYE CONTACT Flush with copious amounts of water for 15 minutes, separating eyelids with fingers. If irritation persists seek
medical aid.
IN CASE OF SKIN CONTACT Wash with soap & water for 15 minutes. If irritation persists seek medical aid.
IF SWALLOWED Call a physician. Wash out mouth with water. Do not induce vomiting without medical advice.
IF INHALED Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Call a
physician.
SYMPTOMS AND EFFECTS Not expected to present a significant hazard under anticipated conditions of normal use.

SECTION 5: FIREFIGHTING MEASURES

SPECIFIC HAZARDS ARISING FROM Not applicable

THE CHEMICAL
FLAMMABLE PROPERTIES May be combustible at high temperature
HAZARDOUS COMBUSTION PRODUCTS Under fire conditions, hazardous fumes will be present.
SUITABLE & UNSUITABLE Small fire: dry chemical, CO₂ or water spray. Large fire: dry chemical, CO₂, alcohol resistant foam or water
EXTINGUISHING MEDIA spray. Do not get water inside containers.
PROTECTIVE EQUIPMENT AND Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
PRECAUTIONS FOR FIREFIGHTERS

SECTION 6: ACCIDENTAL RELEASE MEASURES

PERSONAL PRECAUTIONS Wear respiratory protection. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate
ventilation. Evacuate personnel to safe areas. Avoid breathing dust.
METHODS & MATERIAL FOR On land, sweep or shovel into suitable containers. Minimize generation of dust.
CONTAINMENT

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CLEANUP PROCEDURE Do not touch damaged containers or spilled material unless wearing appropriate protective clothing. Wear
respirator, chemical safety goggles, rubber boots and heavy rubber gloves. Stop leak if you can do it without
risk. Prevent entry into waterways, sewers, basements or confined areas. Shut off all sources of ignition.
Evacuate the area. If necessary, employ water fog to disperse the vapors. Absorb the matter with compatible
vermiculite or other absorbing material. Place in a suitable container and retain for disposal. Ventilate and clean
the affected area. Do not flush into sewerage system or to drains.
REFERENCE TO OTHER SECTIONS See Section 7 for information on safe handling. See Section 8 for information on personal protection equipment.
See Section 13 for disposal information.

SECTION 7: HANDLING AND STORAGE

PRECAUTIONS FOR SAFE HANDLING Do not inhale. Avoid contact with eyes, skin and clothing. Avoid prolonged or repeated exposure. Wash
thoroughly after handling. Store away from incompatible materials, in a well-ventilated area. Eliminate all
sources of ignition. Store in accordance with local regulations. Do not store in unlabeled containers.
Containers that have been opened must be carefully resealed and kept upright to prevent leakage. Use
appropriate containment to avoid environmental contamination.
CONDITIONS FOR SAFE STORAGE Store away from incompatible materials, in a well-ventilated area. Eliminate all sources of ignition. Store in
accordance with local regulations. Do not store in unlabeled containers. Containers that have been opened
must be carefully resealed and kept upright to prevent leakage. Use appropriate containment to avoid
environmental contamination.
STORAGE CONDITIONS Store in original container, tightly sealed, protected from direct sunlight and moisture.
Preserve in airtight container, protected from light.
SPECIFIC END USE(S) See Section 1

SECTION 8: EXPOSURE CONTROLS/ PERSONAL PROTECTION

Chemical Name: CHONDROITIN SULFATE SODIUM CAS #: 9082-07-9

Country Limit value-8 hours Limit value-Short Term IDLH REL Advisory Notes
ppm mg/m³ ppm mg/m³
OSHA USA N/L N/L N/L N/L N/L N/L N/A N/A

ACGIH USA N/L N/L N/L N/L N/L N/L N/A N/A

NIOSH USA N/L N/L N/L N/L N/L N/L N/A N/A

WEEL USA N/L N/L N/L N/L N/L N/L N/A N/A

HSIS Australia N/L N/L N/L N/L N/L N/L N/A N/A

HSE UK N/L N/L N/L N/L N/L N/L N/A N/A

GESTIS Add Country N/L N/L N/L N/L N/L N/L N/A N/A

N/L = Not listed ; N/A = Not Available

PELs are 8-hour TWAs = Limit value - Eight hours
Ceiling or Short-Term TWA = STEL = Limit value - Short term
EXPOSURE GUIDELINES Consult local authorities for provincial or state exposure limits. Particulates not otherwise regulated, respirable
fraction: 5 mg/m³
PERSONAL PROTECTIVE EQUIPMENT Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by WHMIS or OSHA's
eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate
gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.
Respirators: Follow WHMIS or OSHA respirator regulations found in 29 CFR 1910.134 or European Standard
EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are
exceeded or if irritation or other symptoms are experienced. Thermal Hazards: For products representing a
thermal hazard, appropriate Personal Protective Equipment should be used.
SPECIFIC ENGINEERING CONTROLS Adequate mechanical ventilation. Fumehood, eye wash station, and safety shower.

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NOTES Occupational exposure limits: Organic dust, total 3 mg/m³

SECTION 9: PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE Solid

DESCRIPTION White or off-white powder. Is extremely hygroscopic once dried.
SOLUBILITY Freely soluble in water, practically insoluble in acetone and in ethanol (96 per cent).
ODOR Odorless or slightly characteristic
FLAMMABILITY May be combustible at high temperature

AUTO-IGNITION Not available BOILING POINT Not available DECOMPOSITION Not available
TEMPERATURE TEMPERATURE

EVAPORATION RATE Not available EXPLOSIVE LIMIT Not available FLASH POINT Not available

log P Not available LOWER FLAMMABLE/ Not available MELTING/FREEZING Not available
(OCTANOL-WATER) EXPLOSIVE LIMIT(S) POINT

ODOR THRESHOLD Not available OXIDIZING PROPERTY Not available pH 5.5 - 7.5 (1%)

RELATIVE DENSITY 0.3 - 2.0 g/mL SPECIFIC GRAVITY Not available UPPER FLAMMABLE/ Not available
(WATER = 1) EXPLOSIVE LIMIT(S)

VAPOR DENSITY Not available VAPOR PRESSURE Not available VISCOSITY Not available
(AIR = 1)

The physical data presented above are typical values and should not be construed as a specification.

SECTION 10: STABILITY AND REACTIVITY

REACTIVITY Not established

CHEMICAL STABILITY Stable under recommended storage conditions
INCOMPATIBLE MATERIALS Strong oxidants
HAZARDOUS DECOMPOSITION Toxic fumes of carbon monoxide, carbon dioxide, nitrogen oxides and other gases may occur
PRODUCTS
HAZARDOUS POLYMERIZATION Will not occur

POSSIBLITY OF HAZARDOUS Not established

REACTION
CONDITIONS TO AVOID Moisture, sunlight and extreme temperatures

SECTION 11: TOXICOLOGICAL INFORMATION

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ACUTE TOXICITY Oral: Rat: LD50: (mg/kg): > 10 000

Dermal: Rabbit: LD50: (mg/kg): Not available
Inhalation: Rat: LC50: (mg/L/4hr): Not available
SKIN CORROSION/IRRITATION Based on available data, the classification criteria are not met.
Primary skin irritancy test. Result: Non-irritant. Species: Rabbit. Organ: Skin
SERIOUS EYE DAMAGE/EYE Causes eye irritation.
IRRITATION Draize test result: Irritant. Species: Rabbit. Organ: Eye. Severity: Slight.
RESPIRATORY SENSITIZATION Due to lack of data the classification is not possible.

SKIN SENSITIZATION Due to lack of data the classification is not possible.

GERM CELL MUTAGENICITY Based on available data, the classification criteria are not met.
CARCINOGENICITY OSHA CHONDROITIN SULFATE SODIUM is not listed.
NTP CHONDROITIN SULFATE SODIUM is not listed.
IARC CHONDROITIN SULFATE SODIUM is not evaluated.
California This product does not contain any chemicals known to the State of California to cause
Proposition 65 cancer, birth defects, or any other reproductive harm.
ADDITIONAL CARCINOGENICITY Based on available data, the classification criteria are not met.
INFORMATION

REPRODUCTIVE TOXICITY Due to lack of data the classification is not possible.

SPECIFIC TARGET ORGAN TOXICITY - Based on available data, the classification criteria are not met.
SINGLE EXPOSURE
SPECIFIC TARGET ORGAN TOXICITY - Based on available data, the classification criteria are not met.
REPEATED EXPOSURE
ASPIRATION HAZARDS Based on available data, the classification criteria are not met.
SIGNS AND SYMPTOMS OF Not expected to present a significant hazard under anticipated conditions of normal use.
EXPOSURE
POTENTIAL HEALTH EFFECTS Inhalation May be harmful if inhaled. May cause irritation to mucous membranes and respiratory tract.
Ingestion May be harmful if swallowed.
Skin May be harmful if absorbed through skin. May cause skin irritation.
Eyes Causes eye irritation.

SECTION 12: ECOLOGICAL INFORMATION

TOXICITY EC50: 48 Hr: Crustacea: (mg/L): Not available

LC50: 96 Hr: Fish: (mg/L): Not available
EC50: 72 or 96 Hr: Algae (or other aqua plants): (mg/L): Not available
PERSISTENCE AND DEGRADABILITY Not available
BIOACCUMULATIVE POTENTIAL Not available

MOBILITY IN SOIL Soluble in water.

OTHER ADVERSE EFFECTS Not available

This product is not intended to be released into the environment.

SECTION 13: DISPOSAL CONSIDERATIONS

WASTE DISPOSAL Dispose of in accordance with federal / local laws and regulations. Avoid release into the environment.

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SECTION 14: TRANSPORT INFORMATION

UN PROPER SHIPPING NAME Not dangerous good

UN NUMBER Not applicable
CLASS Not applicable
PACKING GROUP Not applicable

AUSTRALIA
HAZCHEM Not Applicable

EU
TRANSPORT IN BULK ACCORDING TO
Not Listed
ANNEX II OF MARPOL 73/78 AND THE
IBC CODE

ENVIRONMENTAL HAZARDS Not available

SPECIAL SHIPPING INFORMATION Not applicable

SECTION 15: REGULATORY INFORMATION

UNITED STATES REGULATIONS

CERCLA SARA (Title III)
Chemical Name EPA 40 CFR Part 355 Right-to-know California
40 CFR 40 CFR
& CAS Appendix A Appendix B Pennsylvania New Jersey Massachusetts Prop 65
Part 302.4 Part 372.65
CHONDROITIN SULFATE N/L N/L N/L N/L N/L N/L N/L N/L
SODIUM 9082-07-9
N/L = Not Listed; X = Listed

AUSTRALIAN REGULATIONS

Therapeutic Goods Code of Practices -

Chemical Name Poisons and Therapeutic
Act Illicit Drug
& CAS Goods Regulation
Precursors
CHONDROITIN SULFATE N/L N/L N/L
SODIUM 9082-07-9
N/L = Not Listed

EU REGULATIONS
Chemical Name REACH REACH EC EC EC EC EC
& CAS ANNEX ANNEX 1005/2009 850/2004 1107/2009 649/2012 2012/118
XVII XIV
CHONDROITIN SULFATE N/L N/L N/L N/L N/L N/L N/L
SODIUM 9082-07-9

N/L = Not Listed; X = Listed

Any EU regulation not listed above is not applicable to this product.

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SECTION 16: OTHER INFORMATION

REFERENCES Available upon request

ABBREVIATIONS AND ACRONYMS ACGIH - American Conference of Governmental Industrial Hygienists; AIHA WEEL – American Industrial
Hygiene Association Workplace Environment Exposure Levels; CAESAR – Computer Assisted Evaluation of
industrial chemical Substances According to Regulations; CAS – Chemical Abstract Service; CERCLA –
Comprehensive Environmental Response, Compensation, and Liability Act; EC50 – Effective Concentration,
50%; EPA – Environmental Protection Agency; GHS – Global Harmonized System; HMIS – Hazardous
Materials Information System; HSE – Health and Safety Executive; HSIS – Hazardous Substances Information
System; IARC – International Agency for Research on Cancer; IDLH - Immediately Dangerous to Life or Health;
IRFMN – Ready Biodegradability Model; ISS – Instituto Superiore Sanità; LC50 – Lethal Concentration, 50%;
LD50 – Lethal Dose, 50%; MSHA - Mine Safety and Health Administration; NIOSH – National Institute for
Occupational Safety and Health; NTP – National Toxicology Program; OSHA PEL – Occupational Safety &
Health Administration Permissible Exposure Limits; QSAR – Quantitative Structure-activity relationship; REL -
Recommended Exposure Limit; SARA – Superfund Amendments and Reauthorization Act; STEL – Short Term
Exposure Limit; TLV – Threshold Limit Value; TWA – Time Weighted Average; WHMIS – Workplace Hazardous
Materials Information System

LAST REVISION 12/2019

SUPERSEDES 01/2019

For a list of changes to the SDS since the last version, please communicate with MEDISCA at
www.medisca.com

DISCLAIMER This document was created in accordance with OSHA, Safe Work Australia and WHMIS regulations. The above
information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide.
The information in this document is based on the present state of our knowledge and is applicable to the
product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of
the product. MEDISCA® shall not be held liable for any damage resulting from handling or from contact with the
above product. Recipients of the product must take responsibility for observing existing laws and regulations.

SUPPLEMENTARY INFORMATION For all country specific requirements not outlined on this Safety Data Sheet, please request Supplementary
Page to this Safety Data Sheet.

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