Drug Action Indication/ Contraindication Nursing responsibilities

Generic Name: Amoxicillin Mechanism of action: Indication:  Observe 12 rights of medication

 Monitor signs of diarrhea, abdominal
Amoxicillin competitively inhibits penicillin- Amoxicillin alone is indicated to treat
pain, fever, pus or mucus in stool,
binding protein 1 and other high molecular weight susceptible bacterial infections of the ear,
Brand Name: Amoxil and other severe or prolonged GI
penicillin binding proteins. nose, throat, genitourinary tract, skin, skin
problems. Notify physician or
structure, and lower respiratory tract.
Side Effects: nursing staff immediately of these
Amoxicillin is given with clavulanic acid to
signs.
Classification: Penicillin Nausea, vomiting, diarrhea, stomach pain, treat acute bacterial sinusitis, community
 Monitor signs of allergic reactions
headache, rash. acquired pneumonia, lower respiratory tract
and anaphylaxis, including
infections, acute bacterial otitis media, skin
pulmonary symptoms (tightness in
Dosage: 500 mg BID Adverse Reactions: and skin structure infections, and urinary
the throat and chest, wheezing,
tract infections.
Itching, shortness of breath, difficulty of cough dyspnea) or skin reactions
swallowing, difficulty of breathing, swelling of Contraindication: (rash, pruritus, urticaria).
Route: PO hands, face, mouth or throat.  Give medication post meal
Amoxicillin is contraindicated in patients
with a known serious hypersensitivity
reaction.
Drug Action Indication/ Contraindication Nursing responsibilities

Generic Name: Paracetamol Mechanism of action: Indication:  Observe 12 rights of medication

 Check that the patient is not taking
Paracetamol is a weak inhibitor of PG synthesis of Used for the treatment of mild to moderate any other medication containing
COX-1 and COX-2 in broken cell systems, but, by pain and reduction of fever. paracetamol
Classification: Analgesic contrast, therapeutic concentrations of
Contraindication:  Evaluate therapeutic response
paracetamol inhibit PG synthesis in intact cells in
 If overdose give N-acetylcysteine 
vitro when the levels of the substrate arachidonic Hypersensitivity.
Dosage: 500 mg 1 tablet q6 acid are low

PRN for pain Side Effects:

Route: PO low fever with nausea, stomach pain, and loss of

appetite, dark urine, clay-colored stools, or
jaundice
Drug Action Indication/ Contraindication Nursing responsibilities

Generic Name: Amlodipine Mechanism of action: Indication:  Observe 12 rights of medication

 Monitor patient’s blood pressure
Amlodipine is considered a peripheral arterial Amlodipine is used with or without other  Monitor cardiac rhythm regularly
vasodilator that exerts its action directly on medications to treat high blood pressure. during stabilization of dosage and
Brand Name: Norvasc vascular smooth muscle to lead to a reduction in Lowering high blood pressure helps prevent periodically during long-term
peripheral vascular resistance, causing a decrease strokes, heart attacks, and kidney problems. therapy.
in blood pressure. Amlodipine belongs to a class of drugs  Document if low blood pressure
Classification: known as calcium channel blockers. 
Side Effects:
Calcium channel blockers Contraindication:
 swelling of your legs or ankles
 tiredness or extreme sleepiness Contraindicated for patients with severe
 stomach pain narrowing of the aortic heart
Dosage:
 nausea valve, significantly low blood pressure,
5 mg OD  dizziness severe liver disease.


Route: PO
Drug Action Indication/ Contraindication Nursing responsibilities

Generic Name: Mechanism of action: Indication:  Observe 12 rights of medication

Acetylsalicylic acid  Assess pain and/or pyrexia one hour
The acetyl group of acetylsalicylic acid binds with Acetylsalicylic acid (ASA), in the regular before or after medication
a serine residue of the cyclooxygenase-1 (COX-1) tablet form (immediate-release), is indicated  Onset is 15-30 minutes, peak 1-2
enzyme, leading to irreversible inhibition. This to relieve pain, fever, and inflammation hours, duration 5-6 hours.
Brand Name: Aspirin
prevents the production of pain-causing associated with many conditions, including
 Discard tablets with vinegar like
prostaglandins. the flu, the common cold, neck and back
smell
pain, dysmenorrhea, headache, tooth pain,
Classification: Side Effects:  Give post meal
sprains, fractures, myositis, neuralgia,
 rash, synovitis, arthritis, bursitis, burns, and
non-steroidal anti-
various injuries.
inflammatory drug (NSAID)  gastrointestinal ulcerations,
 abdominal pain, Contraindication:
Dosage:
 upset stomach,
Contraindicated for patients with peptic
1 tablet OD  heartburn,
ulcer, bleeding disorder, hypersensitivity to
 drowsiness,
NSAIDS, liver disease.

Route: PO