Raising The Profile of Radiation Oncology: Q&A With Astro President Dr. Theodore Deweese
Raising The Profile of Radiation Oncology: Q&A With Astro President Dr. Theodore Deweese
Raising The Profile of Radiation Oncology: Q&A With Astro President Dr. Theodore Deweese
80
Raising
the
profile of
radiation
oncology
Q&A with
ASTRO president
Dr. Theodore DeWeese
p. 36
DOSE OPTIMIZATION
• When it comes to administering CT
scans, how do you ensure a quality
diagnostic image without excess radiation
exposure? p. 52
RADIATION SHIELDING
• Shielding may not be on your mind every
day, but when it's time for a shielding
project you can't afford to make mistakes.
p. 70
CT Solutions in Sight
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CONTENTS
September 2019
52 36
Dose optimization Dr. Theodore DeWeese
An update on finding the balance between quality President
diagnostic imaging and radiation exposure. ASTRO
Raising the profile of radiation oncology.
56
Spectral CT
Value, use cases and implementation insights from
Dr. Nakul Gupta. 60
John Boone
62 Professor of radiology and biomedical
AI comes to the CT market engineering, and chief of
Surveying the latest hardware and software enhancing the medical physics
capabilities of CT providers. University of California Davis
Ultrahigh-res scanning comes to CT.
70
Radiation Shielding
Shielding may not be on your mind every day, but when it's time
for a shielding project, you can't afford to make mistakes.
EDITORIAL
CONTRIBUTING EDITOR Sean Ruck
STAFF REPORTER John R. Fischer
70 CONTRIBUTING WRITERS
Lisa Chamoff
James D’Arezzo
Lauren Dubinsky
Thomas Dworetzky
Nakul Gupta
Deepak “Dee” Khuntia
COLUMNS & SECTIONS John W. Mitchell
Ann Raldow
6
Daily News Round-Up
Luca Valle
Some of the top current events stories from our Daily News online COPY EDITOR David Imber
17
Upcoming Events
DESIGN DIRECTOR
DESIGN
Stephanie Biddle
Mark your calendar for these medical industry DESIGN CONSULTANT Oscar Polanco
conferences and meetings
SALES
18
Hospital Spotlight SALES DIRECTOR David Blumenthal
212-742-1200 Ext. 224
Behind the scenes at Mount Sinai St. Luke’s dblumenthal@dotmed.com
24
Cost Containment Corner ACCOUNT MANAGERS Colm Ford
212-742-1200 Ext. 241
Cost-effective solutions for healthcare IT deficiencies cford@dotmed.com
George Persin
33
View From The Hill 212-742-1200 Ext. 260
gpersin@dotmed.com
Bill aiming to reduce prior authorization delays for cancer
treatment introduced in Congress Have News For Us?
If you have a press release to share with us or an article
you would like to see published, please submit it to:
36
Special ASTRO Section news@dotmed.com
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Auctions
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69 Ten-year study finds low-dose CT is the standard for lung DOTmed.com, please call: 212-742-1200 Ext. 296,
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cancer screening HealthCare Business News is published by DOTmed.com, Inc.,
Research shows that LDCT can reduce deaths from lung cancer by 29 Broadway, Suite 2500, New York, NY 10006
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26 percent in high-risk men and 61 percent in high-risk women
80 Future of radiotherapy
Dr. Deepak “Dee” Khuntia, senior vice president and chief
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Letter from the Editor
A fundraising campaign to help pur- had to travel to Aberdeen for follow-up MR Since the beginning of May, thousands
chase a new MR scanner for Scotland’s scans every three months after having a can- of online sales of the Harriet’s Hat pattern,
remote Shetland Islands has gotten a cerous polyp removed from her colon. along with sales of Shetland wool yarn
boost from one of the region’s oldest Middleton, who says she has immersed from Lerwick retailer Jamieson & Smith and
traditions — knitting. herself in her beloved hobby “through good knitwear from Middleton and her knitting
A year ago, the Shetland Health Board times and bad,” began selling her hand-knit group, called MRI Maakers, has raised nearly
Endowment Fund began a campaign which items at craft shows to raise money for the £25,000, close to 10 percent of the total
aims to raise nearly £1.65 million to purchase a campaign. She then started receiving dona- raised so far, toward the target.
scanner for the archipelago, which consists of tions of yarn from local companies, such as “I was overwhelmed and still am over
16 islands inhabited by roughly 23,000 people. Jamieson’s of Shetland, forming a knitting the response to the campaign,” Middleton
Currently, about 600 patients a year must group to create more items for the fundraiser. told HCB News. “It shows the power of the
travel via plane, or up to 14 hours over often Middleton designed a pattern for a hat internet. I never thought when I decided to
rough seas on an overnight ferry, to either using the blue and orange colors from the do something to help raise money for the
Aberdeen or Glasgow on the Scottish main- campaign’s logo. Her son, Billy Middleton, appeal that my small effort would generate
land to have an elective outpatient MR scan. set up a website and social media accounts so much interest.”
Enter Harriet Middleton, a knitter who to sell and promote the pattern. Share this story: dotmed.com/news/47816
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woman’s dangerous breathing ills
dotmed.com/news/48183
@dotmedcom
HealthCare Business News I september 2019 7
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Last week, the Trump administration exclusion for some of its equipment after “If tit-for-tat retaliation continues, the
announced it would exempt 110 Chi- claiming that that the tariffs would only hurt administration’s objectives for a strong do-
nese products, including some medical their firm, as there are no other “good alter- mestic medical technology industry will be
equipment, from its 25 percent tariffs natives,” noted Reuters, and that it would undermined. We ask the administration to
placed on $34 billion of Chinese imports hurt it against European competitors. consider this adverse impact and to remove
on July 6, 2018. Other device components that have been all medical technology products from its re-
The exclusions are retroactive to that exempted include “veterinary ultrasound taliation lists,” it stated.
date, according to Reuters, and will be in devices, certain parts and accessories of elec- In addition, it urged that, “including med-
place for a year from last Tuesday. tro-surgical instruments, and dental X-ray ical technology products on the USTR list is
The U.S. has levied tariffs on $250 billion alignment and positioning apparatuses,” ac- troubling from a public health perspective.
of imports from China and now threatens cording to a report in Medtech Dive. Healthcare products have been consistent-
to tax another $300 billion, as the two na- But according to a June statement to ly recognized as being exempt from trade
tions continue going back and forth with USTR by the Advanced Medical Technology sanctions — even with countries which the
one another. (AdvaMed) Association, which represents United States considers to be security risks.”
There were 12 exclusion requests grant- over 400 medical device makers, many An ongoing trade war could threaten the
ed to Medtronic, including one for a com- devices that the group hoped would be 30 percent market share U.S. makers enjoy
ponent in a device used to treat liver tumors. exempted, including pacemakers, remain in China, AdvaMed noted.
Varian Medical Systems also received an subject to the 25 percent tariff. Share this story: dotmed.com/news/47897
Improving consumer experience is top periencing improved quality outcomes and lowed by greater patient adherence to care
or second among the priorities of 69 improved patient engagement, while 65 plans, reductions in unnecessary utilization/
percent of healthcare C-suite executives, percent report a higher number of patients readmissions, and improved patient reten-
according to a survey conducted by re- sticking to care plans, and 54 percent seeing tion. While 81 percent of C-suite executives
search firm Sage Growth Partners. improved patient retention. use navigators with clinical backgrounds,
Commissioned by healthcare experience Utilized the most in oncology, orthope- programs of high value rely on non-clinical
and patient navigation enterprise, Docent dics and cardiology, the adoption of patient navigators, which were found to be more
Health, the survey examines strategies imple- navigation programs is mainly stimulated by effective than clinical ones.
mented by hospitals across the country to a desire to improve patient engagement, fol- Share this story: dotmed.com/news/47831
improve such experiences, a task which is
becoming essential due to changes in how
healthcare services are managed and paid
for, says Stephanie Kovalick, chief strategy
officer for Sage Growth Partners.
“Consumers are starting to feel a higher
burden of paying for services themselves,” she The Accurate and Affordable Answer to Home Reading
told HCB News. “Healthcare consumers have LG 27" 8MP Clinical Review Monitor
anywhere from $2500-$10,000, and some-
times even more in deductibles, so they’re
paying for so much care out-of-pocket. As you
start to spend your own money, you’re much
more careful about the choices you make
in how to spend that money. We’re seeing
healthcare consumers a lot more discerning in
where they’re going to receive care and how
they make decisions for follow-up care based
on the experience they had the first time.”
The surveyors spoke to 100 healthcare
C-suite executives from different hospitals
across the country in the first quarter of
2019, with 64 percent from highly com- 27HJ713C-B
Micro-X has manufactured a new car- to introduce carbon nanotube X-ray tech- of this sum was supported by funds from a
bon nanotube X-ray tube for its plat- nology to the medical imaging field, and as $2.4 million matching grant secured under
form of X-ray products. our sales of this new device grow, Micro-X the Federal Government’s Advanced Manu-
Composed of a carbon nanotube elec- is well-positioned to quickly supply antici- facturing Growth Fund.
tron emitter, development of the tube will pated demand from customers.” The process involved key elements such
make Micro-X one of two companies in CNT-based X-ray tubes are the first to as design, process engineering, production
the world capable of developing CNT- not use heated-filament electron emission, engineering and validation and testing. It
based X-ray tubes, alongside third-party reducing size, weight, heat and power. also focused on improving existing reliabil-
supplier, XinRay, for products such as the Originally relying on XinRay for manufac- ity standards and garnering support from
Carestream DRX-Revolution Nano mobile turing, Micro-X set to work developing its stakeholders to create a smooth transition
X-ray system. proprietary CNT emitter in 2017 at its base from the current supplier to Micro-X inter-
“The advances Micro-X has made in Adelaide, Australia, employing a small nally manufactured X-ray tubes.
in this new X-ray tube design — both in team of world-leading experts in engineer- In developing its own tubes, the compa-
the quality and potential lifetime of this ing chemistry and nanomaterials science to ny expects to achieve increased commercial
innovative new tube — will be of great work alongside researchers at Flinders Uni- margins and enhanced flexibility in future
benefit to healthcare providers,” Charlie versity and the University of Adelaide. product designs, including for the Rover and
Hicks, general manager of X-ray solutions The total cost of the project was approxi- Mobile Backscatter Imager product that is
at Carestream Health, said in a statement. mately $3 million, including for the develop- being developed with Thales.
“We at Carestream are the first company ment work and new capital equipment. Part Share this story: dotmed.com/news/47962
Chest X-rays may hold more information that could identify Administering low-radiation doses equivalent to that of
patients at high risk for a range of conditions, including heart three CT scans may boost the number of cancer-capable cells
disease and lung cancer. over normal cells in healthy tissue, according to a new study.
That’s the consensus arrived at by researchers at Massachusetts Researchers at the Wellcome Sanger Institute and the University
General Hospital, who have developed a new AI tool called CXR-risk of Cambridge used mice to show that low doses of radiation in-
to determine which patients would benefit the most from screening crease the number of cells with mutations in p53, a genetic change
and preventive medication. associated with cancer. They argue that such a risk should be con-
“We developed and tested this convolutional neural network sidered in radiation safety assessments.
in healthy outpatients. The hope is that it will help primary care “The reduction in radiation exposure is desirable, and limiting
physicians and patients make decisions about prevention, screen- imaging and using optimized scanning protocols are important
ing, and lifestyle,” Dr. Michael T. Lu, director of research of MGH ways forward,” professor Phil Jones of the Wellcome Sanger Insti-
Cardiovascular Imaging, told HCB News. The underlying idea is that tute and MRC Cancer Unit at the University of Cambridge, and Dr.
we can use CNNs to extract information about health and longevity David Fernandez-Antoran of the Wellcome Sanger Institute, told
embedded in everyday medical images.” HCB News.
Trained on analyses of more than 85,000 chest X-rays from Although information on the impact from exposure to low levels
42,000 subjects, the solution is designed to identify combinations of radiation is limited, all humans carry cancer-capable mutant cells
of features on a chest X-ray that best predict health and mortality. in healthy tissue, including those with p53 mutations. Cells with
Each image used to train it included information on whether or not this mutation increase in number as a person ages, though very
the person died at any point over a 12-year period. few turn into cancer.
Share this story: dotmed.com/news/48007 Share this story: dotmed.com/news/48049
A survey conducted of a small sample of “[With conversational AI,] I would be Increased patient and reporting work-
radiologists at academic medical centers, able to extract data and put it into more loads have created what the president of
healthcare systems, radiology practices, structured reports,” said Dr. Brian Kaineg, the World Medical Association has called a
and hospitals confirmed a litany of radiol- neuroradiology, Quantum Radiology. “That “pandemic of physician burnout,” according
ogist workflow and practice complaints, would be ideal because then you could set to the report, which is entitled In your words:
such as tedious methods of measure- up a template that everything populates How AI is advancing the impact of radiology
ment, job burnout, and inefficient work- into and the radiologists wouldn’t neces- in healthcare. Porter Research conducted the
flow in the face of increasing workloads. sarily need to change the way they’re rou- survey between January and March of 2019.
The report, which consisted of interviews tinely dictating.” Share this story: dotmed.com/news/47789
with nine radiologists and their response to
23 questions, was prepared by Porter Re-
search and sponsored by imaging AI solu-
tions company, Nuance Communications.
Nuance released the report at the 2019 SIIM
annual meeting currently convened in Au-
rora, Colorado.
“Radiologists are being pressured by larg-
er and larger workloads, due, in part, to ris-
ing patient volumes and inefficient systems
and processes,” Karen Holzberger, vice presi-
dent and general manager of diagnostics for
Nuance, told HCBN. “The unfortunate result
is that many radiologists are burned out. We
wanted to hear directly from the source on
what can be done to alleviate the stress and
tension, and specifically, what role can in-
novative technology play?”
Dr. Alexander Towbin, a radiologist in the
department of radiology and medical im-
aging at Cincinnati Children’s Hospital, said
radiologists deliver a service in an expensive
environment that needs to be efficient.
“Workflow efficiency is something that
I believe is important,” said Towbin. “We all
know ... medical costs are out of control, and
no one can afford them; so we need to be ...
cognizant of what we spend and what we
ask for our patients.”
Holzberger said that incorporating narrative
reporting into structured data and integrating
intelligence and AI-generated findings directly
into the workflow to automate and augment
reports is a proven solution. The access to AI,
pre-populating data within reports, automat-
ing repetitive or time-consuming routine tasks,
structured reporting formats, and other fea-
tures are recognized as high-value capabilities.
HealthCare Business News I september 2019 11
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Shenzhen-based Mindray Bio-Medical But some think it may have gone a bit in 2016.
Electronics has soared since going pri- too far, a little too fast, with a P/E ratio of The maker of in-vitro diagnostics equip-
vate in 2016, and is taking market share 39, despite a Bloomberg forecast of a 20 ment, life monitoring systems and medical
from both GE and Siemens. percent revenue growth and 21 percent an- imaging equipment, including color ultra-
And in May it got put into the MSCI nual income growth from now to to 2021. sound devices, has been liked by institutional
China All Shares Health Care 10/40 Index, That’s because the consensus price tar- investors, thanks, in part, to its rising R&D
which “captures large and mid-cap repre- get for Mindray is 158.90 yuan, showing a investment, and government support as
sentation across China A-shares, B-shares, possible 3.8 percent downside from present China seeks to become a bigger player in
H-shares, Red-chips, P-chips and foreign list- stock values. the global market, according to Bloomberg.
ings,” according to MSCI, and which “aims The company is “looking expensive,” al- At present prices, there are those who
to reflect the opportunity set of China share though not too much so versus other China think the values are a bit high and are hold-
classes listed in Hong Kong, Shanghai, Shen- high-fliers, like soy sauce maker Foshan Hai- ing off. Dai Ming, portfolio manager of
zhen and outside of China.” tian Flavouring & Food, Xiong Qi of Windsor Hengsheng Asset Management Co., told
Its stock has risen 51 percent, making it Capital Management told Bloomberg. Bloomberg that, “Mindray’s valuation is too
“a top performing equity on the ChiNext The firm had been listed in the U.S. on high. We will wait for a pullback to get in at
board” — and that has given it a $29 billion the NYSE until being taken by a subsidiary a more reasonable price.”
valuation, according to Bloomberg. of Excelsior Union Limited for $1.9 billion Share this story: dotmed.com/news/47896
Rising healthcare spending by the Chi- and we expect it to continue in the coming crease the amount by which our earnings
nese government boosted Philips to years,” he explained to the news agency. are hit by 20 million euros this year, but no-
above-expectations sales growth in Q2 Sales rose in the U.S. and Europe as well, body knows whether it will happen.”
— with comparable sales up 6 percent according to the company. The company now anticipated that it will
versus a 4.5 percent analyst forecast. “We saw growth in all our segments in lose about $51 million of earnings in 2019
The company saw a “double digit” sales the second quarter and we expect that to due to tariff impact.
rise in China, according to Reuters, due in continue,” Van Houten said, adding that, Despite that, the presently forecast 4
part to government expansion of hospitals “we had strong traction in emerging mar- percent to 6 percent total comparable sales
and purchase of more high-tech healthcare kets and that is set to continue. Also, we growth through 2020 remains in place, with
equipment. expect mature markets to come in stronger a projected profit margin up from 13.1 per-
“Healthcare in China is still not sufficient to in the second half of the year.” cent to 14 percent for the year.
meet the demands of an aging society,” Phil- Despite the positive sales news, the com- Adjusted earnings before interest, taxes
ips CEO Frans van Houten told Reuters. pany advised that ongoing tariff woes will and amortization (EBITA) rose 14 percent to
“The government has said it would impact both its components and products. 549 million euros in the second quarter, and
expand capacity, and that is exactly what “The main cloud hanging over us is the margin grew 11.8 percent, near expecta-
is happening. This trend for us is more im- possible fourth batch of tariffs,” Van Houten tions, said Reuters.
portant than fluctuations in GDP growth, stated. “If that would happen, it would in- Share this story: dotmed.com/news/48024
The Centers for Medicare and Medicaid Services has pro- The U.S. is among the countries spearheading the adoption
posed an advanced alternative payment model for providers of digital health records globally... In fact, it’s the only digital
administering radiation oncology procedures. technology that the U.S. leads in healthcare, according to
Aimed at supporting the transition toward value-based care, Philips’ U.S. Future Health Index 2019 Report.
the Radiation Oncology (RO) Model encourages the adoption of The Dutch-based healthcare giant ranks the “Land of Opportu-
prospective site-neutral, episode-based payments by physician nity” below the 15-country average leveraging the full use of digital
group practices, hospital outpatient departments, and freestanding healthcare technologies, including telemedicine and AI. And while
radiation therapy centers for radiotherapy. This model is expected used by 84 percent of U.S. healthcare professionals, DHRs still come
to reduce Medicare expenditures, while maintaining or enhancing with their share of challenges.
the quality of care for Medicare beneficiaries. “Federal legislation, such as the HITECH Act, helped drive adop-
“The new model provides incentives for high-quality, more tion of DHRs over the last ten years and helped U.S. healthcare
convenient radiation treatments and rewards concordance with move away from disparate, paper-based processes to digital re-
evidence-based clinical guidelines,” Dr. Brian Kavanagh, immedi- cords,” Dr. Joseph Frassica, head of Philips Research, the Americas,
ate past chair of ASTRO, told HCB News. “The model also has the and chief medical officer at Philips North America, told HCB News.
potential to stabilize reimbursement in the long term and move the “Unfortunately, this rush to digitize came without common indus-
specialty from an antiquated fee-for-service payment structure to try standards for data exchange and normalization, contributing to
one based on quality and value.” data silos and interoperability challenges.”
The prospective episode-based payments would apply to the Lack of standardization hinders interoperability, with 52 percent
treatment of 17 types of different cancers, with providers receiving of American healthcare professionals less inclined to share health
payments during a 90-day period of care. CMS expects it to save records among their peers inside their own facilities.
$260 million for Medicare in that time. Share this story: dotmed.com/news/48008
Share this story: dotmed.com/news/47911
HealthCare Business News I september 2019 13
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Siemens Healthineers has teamed up research, innovation, engagement and inclu- Among the equipment supplied will
with the University of Missouri System sion,” said UM System President Mun Y. Choi be laboratory and imaging technology, in-
(UM System) and University of Missouri in a statement. “Forming an alliance with Sie- cluding the MAGNETOM Terra 7 Tesla MR
Health Care (MU Health Care) to estab- mens Healthineers enables us to work toward scanner, for clinical and research purposes
lish the Alliance for Precision Health. this mission by providing our university and focused on furthering ultra-high field MR
The German-based healthcare giant has health system with leading-edge technology capabilities. The UM System will also have
entered into a $133 million 10-year Value and resources, unique research and collab- access to Siemens’ AI and health digitaliza-
Partnerships agreement with UM System, oration opportunities, training for the next tion tools, such as syngo Virtual Cockpit, a
which includes all four universities, and generation of the healthcare workforce, and software solution for connecting radiology
MU Healthcare, in which it will supply both expansion of our contributions to medicine technicians remotely to scanner workplaces
southern entities with diagnostic and thera- and healthcare to rural Missouri and beyond.” to help personnel in different locations with
peutic devices to enhance care delivery, pro- The alliance is expected to help the UM Sys- sophisticated exams. Enterprise services and
mote education around technology and en- tem complete research, educational and clinical digital solutions will be provided as well, with
gineering, and help create research ventures. care objectives for its highest priority, NextGen Siemens utilizing insights about their prod-
“Our vision for the entire UM System Precision Health Initiative, a statewide effort ucts from the UM System and MU Health
is to advance the opportunities for success to provide treatments for cancer, Alzheimer’s, Care to improve upon the development of
and well-being in Missouri, the nation and cardiovascular disease and other illnesses that their medical technologies and services.
the world through transformative teaching, affect Missourians and people worldwide. Share this story: dotmed.com/news/47913
Canon’s extraordinary deal structure so we are fining Canon €28 million. Our “As a second step, following approval
when it picked up Toshiba Medi- merger assessment and decision-making of the merger by the Commission, Canon
cal Systems Corp. (TMSC) has now depends on the Commission being sure that exercised its share options, acquiring 100
earned it a 28 million euro ($32 mil- companies are not jumping the gun and im- percent of the shares of TMSC.”
lion) fine from the European Commis- plementing mergers without our approval.” This is far from the first objection incurred
sion, Bloomberg reports. The EU further broke down the manner over the deal structure.
At issue was a tactic dubbed “warehous- in which Canon’s warehousing broke the Earlier in June, the Canon-Toshiba deal
ing” that got around filing requirements, EU rules. earned the companies fines of $2.5 million
antitrust enforcers said in a statement. “For the acquisition, Canon used a so- each to settle U.S. federal charges that they
“Companies have to respect our com- called “warehousing” two-step transaction violated premerger notification and wait-
petition rules and procedures, said Com- structure involving an interim buyer. ing period requirements of the Hart-Scott-
missioner Margrethe Vestager, in charge of “As a first step, the interim buyer ac- Rodino (HSR) Act with the unusual nature of
competition policy, adding that companies quired 95 percent in the share capital of the 2016 transaction.
“are obliged to notify and wait for our ap- TMSC for 800 euros, whereas Canon paid The settlement also requires that the
proval before a merger can go ahead.” 5.28 billion euros for the remaining 5 per- companies put in place HSR compliance pro-
Of the warehousing he noted, “Canon cent of the shares and share options over the grams and agree to inspection and reporting
structured a transaction to circumvent these interim buyer’s stake. This first step was car- requirements.
obligations when they acquired TMSC. This ried out prior to notification to or approval Share this story: dotmed.com/news/47787
is a procedural breach of our merger review by the Commission.
The global breast ultrasound market is peat scans,” Poornima Srinivasan, industry ing programs such as ABUS, which takes less
projected to reach $1.71 billion by 2023, analyst, transformational health at Frost & than 20 minutes for scanning.
according to Global Breast Ultrasound Sullivan, told HCB News. “In this context, Additional tasks that help include realign-
Market, Forecast to 2023, a report by automated breast ultrasound offers value in ing care models, focusing on automation
research firm Frost & Sullivan. terms of lesser time of less than five minutes and wireless, and expanding new clinical
Valued currently at $1.11 billion, use of and helps eliminate operator/sonographer areas such as optical ultrasound; improv-
novel techniques by vendors, combined with error as the ultrasound probe placement and ing the value proposition across clinical and
machine learning and deep learning algo- movement on the breast are standardized.” financial stakeholders and providing value
rithms for high-quality imaging and capa- Innovations like miniaturization, nonin- for better managed equipment services,
bilities, such as cloud and data analytics, are vasiveness, higher affordability and painless training, and technical upgrades; and offer-
expected to be the main drivers of growth, diagnosis are expected to further boost the ing usage-based, service-oriented delivery
along with proactive introduction of applica- use of ultrasound scanners. models in developing economies.
tions and value-based equipment by vendors Vendors seeking to benefit from this rise Srinivasan says that Asia-Pacific countries
based on regional needs. in the market are advised in the report to such as China and Japan offer opportunities
“Traditional breast ultrasound generally demonstrate evidence-based benefits such for ultrasound as a primary diagnostic tool,
faces issues in terms of longer examination as cost efficiency, improved clinical out- and that new business models focused on
times (more than 30 minutes) and sonog- comes and time efficiency of their solutions, operational efficiency and training will help
rapher error, depending on the character- as well as adopt targeted approaches that to increase its use in developed nations.
istic of breast tissues, which necessitates re- increase procedural volume in breast screen- Share this story: dotmed.com/news/47834
Mayo Clinic is set to build a new $233 million integrated oncolo- Transacted revenue skyrocketed to $11.3 billion for the
gy facility including proton beam therapy on its Florida campus. second quarter of this year, almost four times higher than
The 140,000-square-foot facility, which will house a two-gantry that generated in the same time last year.
proton system, is now scheduled for a late 2023 opening, according These were the findings of a new Kaufman Hall report on
to a Mayo statement. merger and acquisition activity, and come despite a decline in the
“This facility will give us the ability to offer our patients the full spec- number of hospital and health system mergers and acquisitions
trum of cancer treatment options, including chemotherapy, immunother- in the same period.
apy, CAR-T cell therapy (chimeric antigen receptor therapy T cell therapy), “This trend is simply a response to the changing market,” Anu
surgery, proton beam therapy, gamma knife radiosurgery and traditional Singh, managing director at Kaufman Hall, told HCB News.
radiotherapy,” CEO of Mayo Clinic in Florida, Dr. Kent Thielen stated, The healthcare industry is under a high degree of uncertainty
adding that, “it will also give patients access to proton beam therapy due to the pressure to take on more risk while continuing to cut
clinical trials offered through our National Cancer Institute-designated costs. On top of that, organizations may have trouble competing
comprehensive cancer center.” against new disrupters in the industry, such as Amazon, CVS and
The new facility will be near the Mangurian Building, which offers United Healthcare.
hematology and oncology care, and the Oncology Infusion Center, in “Even larger organizations that have made strides in build-
order to better integrate cancer care on the campus. ing up sites of care and pursuing ambulatory strategies could
Proton therapy had already been added to the rosters of other also not have the financial or intellectual capital to thrive in a
Mayo Clinic campuses in Rochester, Minnesota, in 2015 and Phoenix value-based world where clinical and business intelligence are
in 2016. critical,” said Singh.
dotmed.com/news/47753 Share this story: dotmed.com/news/48065
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HealthCare Business News I september 2019 17
Hospital Spotlight: Mount Sinai St. Luke’s
Noteworthy distinctions:
First hospital in New York State to offer TECAB
1
(totally endoscopic coronary artery bypass sur-
gery), performed using micro-incisions. It offers a
quicker recovery time, decreases pain, and lessens 2
the risk of infection.
Verified as a Level II Trauma Center by the Veri-
fication Review Committee, part of the Commit-
tee on Trauma of the American College of Sur-
geons. This achievement recognizes the trauma
center’s dedication to providing optimal care for
injured patients.
Recognized by the American College of Surgeons
as an Accredited Comprehensive Bariatric Center.
Recent developments:
Opened in 2017, the Center for Clinical Cardio-
vascular Care offers a suite of specialty services
for comprehensive and integrated cardiovascular
patient care. An additional improvement to the
heart program includes a new catheterization lab.
The Imaging Suite is a 24/7 subspecialty ser-
vice with state-of-the-art scanning equipment,
including the use of MR and CT for neuroimag-
ing, cancer imaging, and cardiac imaging.
A new Surgery Practice Space opened in July
2019, featuring a modern design, with 14 extra
rooms equipped with state-of-the-art technol-
ogy to evaluate patients for potential surgery
4
in several subspecialties, including General Sur-
gery, Bariatric Surgery, Surgical Oncology, and
Colorectal Surgery.
A future-state Cancer Center will feature
a comprehensive cancer program, providing
screenings, medical oncology, and surgical on-
cology. The Infusion Suite, which opened in
2018, is the first step in making this program.
The Ambulatory Care Center Lobby was ren-
ovated and reopened in May 2018.
The Main Hospital Lobby will be revamped next
year. In 2020, we will also be adding a single-bed-
ded inpatient unit and a medicine practice space.
Q&A with
Art Gianelli
president of Mount Sinai St. Luke’s
Delivering healthcare in a 'Lean'
framework
By Sean Ruck
HealthCare Business News spoke with challenges facing that institution, I think we did occurred. We’ve targeted certain services to
Art Gianelli, MBA, MPH, president of really remarkable work in terms of improving expand and grow — cardiology, cardiac sur-
Mount Sinai St. Luke’s, to get the de- quality and safety and starting to recover the gery, bariatric surgery, orthopedic trauma,
tails his unique background brings to his finances of the hospital. We also reinvested cancer and our geriatric program.
role, and to hear his insight about the in the hospital in ways that hadn’t been done Staff are attracted to the opportunity to
hospital and healthcare overall. previously. We also encouraged the staff to work for the Mount Sinai Health System. They
believe that transformation was possible. And are also attracted to working for a hospital
HCB News: What inspired you to pur- finally, I joined a number of boards across the whose services are growing and increasing in
sue a career in healthcare? country. I was on the executive committee of complexity. Mount Sinai St. Luke’s is a Lean
Art Gianelli: My path was not a tradi- America’s Essential Hospitals, the regional pol- hospital. When I first came to Mount Sinai,
tional one. I worked for a significant time in icy board for the American Hospital Associa- I advised Dr. Ken Davis, the president of the
local government: first, as a director of op- tion, the executive committee for Healthfirst. Mount Sinai Health System, that my experi-
erations for a town, then as a deputy county My goal was to gain knowledge and insight ence of running a hospital was through a Lean
executive for budget and finance. My ex- into running a hospital. Now, I actually teach framework and that’s what I wanted to do here
pertise was in finance, turnaround manage- hospital operations at Columbia University and at St. Luke’s. He was absolutely encouraging.
ment and strategic planning. at Mount Sinai. I’m proud of that, because it From day one, that’s what we’ve done here.
While I was deputy county executive, I wasn’t too long ago that I was just embarking We’ve used Lean to develop our daily manage-
was approached by the consultants the on a career as a healthcare administrator. ment system, for process improvement and to
county had hired to help develop a strategic
galvanize and energize the culture.
plan for its affiliated public hospital. The hos- HCB News: How long have you been It’s evident to anyone who comes here,
pital was chronically challenged, financially with Mount Sinai St. Luke’s? that the experience of working at St. Luke’s
and otherwise. The consultants wanted me AG: I’ve been with the Mount Sinai is different than at other hospitals. Here, the
to run the hospital. I laughed. I told them I Health System since February 2014. wisdom of the frontline staff is valued and
had not run a hospital before, I’d been suc-
cultivated. We want our frontline workers
cessful in my career, but that’s a challenge HCB News: What attracts staff to
to be emissaries of problem solving. I think
not like any other. And no one had been Mount Sinai St. Luke’s?
people who are attracted to that and that
successful historically in running that hos- AG: Similar to my prior hospital, Mount
level of agency with respect to their work,
pital. However, the more I thought about it, Sinai St. Luke’s needed a turnaround strat-
really want to come here. We also try to em-
I believed in the hospital’s mission and the egy. That was very clear to the leadership at
phasize the tenets of a just culture. Errors,
population it served and I decided to look Mount Sinai and that was my charge here at
when they do occur, are typically associated
at it as a real opportunity. I decided to take St. Luke’s. There’s been well over $100 million
with system and process failures.
a chance and go for it. I advised the consul- of capital investment to build an ambulatory
tants that they needed to persuade my wife, platform, to upgrade equipment, to replace HCB News: Can you tell us roughly
who was adamantly opposed to this, being the EMR, to transform the appearance and what the makeup of your patients is
very familiar with the hospital and its history. operation of the organization. There have also from a payor perspective?
But they were able to persuade her as well. been investments in the hiring of staff to cover AG: About 85 percent of the patients that
I took the leap and started my tenure. gaps in our hospital service, and we’ve hired receive care at Mount Sinai St. Luke’s are in-
Given the constraints we were under and the staff to keep up with the volume growth that’s sured by the government, either through Medi-
Fortunately, many in the imaging commu- more systems the radiologist has to work with.
Dr. Chris Roth
nity are working to bridge the data divide Part of the blame lies with physicians and hos-
between imaging and the EHRs. When you pitals permitting imaging metadata variation.
consider the spectrum of clinical multimedia Different scanner manufacturers call
in radiology, cardiology, ophthalmology, ob- nearly identical sequences by different
stetrics, the emergency department, opera- names. Different scanners within a hospi-
tive suites, dermatology and other medical tal may or may not have similar imaging
specialties, the opportunity is significant. metadata, depending on who configured
Most providers have the ability to take a the scanner, the scanner age, and how long
patient photo or video, integrate it into the ago those metadata were last reviewed.
electronic medical record, and assign some Until recently, there was no ability to cen-
straightforward metadata to it using the In- trally modify and standardize the image data
tegrating the Healthcare Enterprise Radiol- capture configurations on many devices at
ogy’s Encounter Based Imaging Workflow once. Integrating the Healthcare Enterprise
(IHE EBIW) profile. But this profile requires Radiology recently created a profile called
Hospitals and doctors are required to build work within and between institutions Management of Acquisition Protocols (IHE
use electronic health records or get hit to create appropriate clinical workflows and MAP) so that a leader technologist and
with financial penalties under Medicare interoperable data. “When capturing imag- physician can jointly and centrally review
reimbursement rules. While the rules have es, medical professionals often still disagree and modify the configurations of the entire
been around for years and most providers with the terms to use to describe the body scanner fleet, permitting consistent meta-
are following them, it doesn’t mean it’s been part,” says Roth. The HIMSS-SIIM Enterprise data capture, even across scanner vendors.
easy or that data improvement is where it Imaging Community is tackling this challenge “Most hospitals around the country keep
needs to be today. to determine the optimal ontology to consis- scanners for more than five years, often up
Part of the problem is the fact that in- tently describe body parts. Roth continues, to 10 years,” Roth says. “Some scans will
teroperability, even among the same type “Pretend there is an open fracture of the always only have older sequences, and thus
of technology, hasn’t met the expected or upper arm. The big bone in an X-ray of the older metadata describing them unless the
promised standards. Different vendors have upper arm is called the humerus. Taking a institution puts in the effort to standardize
had different levels of success, but that’s easy photograph of the broken bone sticking out how they capture scans. IHE MAP can assist
to understand. After all, putting a lot of re- of the same upper arm, the body part might with this data standardization and should be
sources into ensuring your tech plays well be described as arm or skin. True interopera- requested of scanner manufacturers during
with a competitor’s technology while having bility means the X-ray and the photo need to the RFP process as a play toward imaging
no assurances that they’re doing the same, relate to each other in computer terms, and data interoperability.”
is a tough pill to swallow. we must agree on those terms, so providers The inconsistencies create at least one
Dr. Chris Roth, associate professor of can consume them in the EHR together. additional source of friction. AI, which re-
Radiology, vice chair Information Technol- So it’s clear that the technology at many lies on accurate and consistent data as its
ogy and Clinical Informatics, director of Im- sites isn’t exactly delivering what’s needed for lifeblood, suffers. A radiologist who verbally
aging Informatics Strategy at Duke Health interoperability with imaging. But how well dictates in a less-structured way what they’re
explained the even greater interoperability are imaging departments complying? In a seeing, either due to limited technology or to
challenge that’s found between imaging in- broad sense, not too well. Part of the blame preference, isn’t adding clean and clear data.
formatics and EHRs. “Compared to many lies with the vendors, with different vendors On the other hand, a radiologist with current
other areas of medicine, Interoperability in having different ways of labeling very similar technology and a mind for innovation may
imaging is unique because you’re dealing techniques and different ways of capturing use more structured terms computers can
with a unique imaging format and com- and incorporating images into the systems, understand.
munications standard in DICOM,” he says. meaning the task is exponentially harder the Share this story: dotmed.com/news/48317
Managing health- and physicians’ offices, end up with dupli- and widespread databases, pulling information
care these days cate EHR data that requires extensive (not to together through millions of I/O operations.
is as much about mention non-productive) search and retriev- The system’s analytic capability is dependent
managing data as al, which degrades IT system performance. on the efficiency of those operations, which,
it is about manag- in turn, is dependent on the efficiency of the
ing patients them- More data, more problems computer’s operating environment.
selves. The tsunami IT departments are struggling to keep up with In the Windows environment especially
of data washing over demand. Like the proverbial Dutch boy with (which runs about 80% percent of the world’s
the healthcare industry is a result of techno- his finger in the dyke, it is difficult for IT staff to computers), I/O performance degradation
logical advancements and regulatory require- manage the sheer amount of data, much less progresses over time. This degradation, which
ments coming together in a perfect storm. But the performance demands of users. can lower the system’s overall throughput
when it comes to saving lives, the healthcare The applications are getting more robust, capacity by 50 percent or more, happens in
industry cannot allow IT deficiencies to be- systems are generally more reliable, but any storage environment. Windows penal-
come the problem rather than the solution. speed (performance) is a constant challenge izes optimum performance due to server inef-
According to a recent report from Inter- that can get worse by the day. ficiencies in the handoff of data to storage.
national Data Corporation, the volume of From an IT investment perspective, im- This occurs in any data center, whether it is in
data processed in the overall healthcare sec- provements in technology have given us the cloud or on premises. And it gets worse
tor is projected to increase at a compound much faster networks, much faster process- in a virtualized computing environment. In a
annual growth rate of 36 percent through ing and huge amounts of storage. Virtualiza- virtual environment the multitude of systems
2025, significantly faster than in other data- tion of the traditional client-server IT model all sending I/O up and down the stack to and
intensive industries. has provided massive cost savings. And new from storage create tiny, fractured, random
Healthcare faces many challenges, but hyperconverged systems can improve per- I/O that results in a “noisy” environment that
one that cannot be ignored is information formance as well in certain instances. Cloud slows down application performance. Left un-
technology. Without adequate technology computing has given us economies of scale. treated, it only worsens with time.
to handle this growing mountain of often But costs will not easily be contained, While additional hardware can temporar-
complex data, medical professionals and sci- as the mounting waves of data continue to ily mask this degradation, targeted software
entists can’t do their jobs. pound against the IT breakwaters. can improve system throughput by up to 30
to 50 percent or more. Software like this has
Electronic health records Containing IT costs the advantage of being non-disruptive (no
Over the last 30 years, healthcare organiza- Costs continue to rise, proportionate to the ripping and replacing hardware), and it can
tions have moved toward digitizing patient demand for the three fundamentals (appli- be transparent to end users as it is added in
records, with 96 percent of U.S. hospitals cations, uptime and speed). the background. Thus, a software solution can
and 78 percent of physician’s offices now us- However, there are solutions that can help handle more data by eliminating overhead, in-
ing EHRs, according to the National Acade- contain IT costs. Data Center Infrastructure creasing performance at a much, much lower
my of Medicine. A recent report from market Management software has become an effec- cost and extending the life of existing systems.
research firm Kalorama Information states tive tool for analyzing and then reducing the With the tsunami of data threatening IT,
that the EHR market topped $31.5 billion in overall cost of IT. In fact, the U.S. government solutions like these should be considered in
2018, up 6 percent from 2017. Data Center Optimization Initiative claims to order to contain healthcare IT costs.
The adoption of EHRs is supposed to be have saved nearly $2 billion since 2016. James D’Arezzo is CEO of Condusiv Tech-
a solution, but instead it is straining an over- What is often overlooked is that processing nologies, a global provider of software-only
burdened healthcare IT infrastructure. This is and analyzing data is dependent on the over- storage performance solutions for virtual
largely because of the lack of interoperability all system’s input/output performance. Many and physical server environments.
among the more than 700 EHR providers. large organizations performing data analytics Share this story: dotmed.com/news/48318
Healthcare organizations, primarily hospitals require a computer system to access multiple
RELATIONSHIPS MATTER
BUILD RELATIONSHIPS WITH 100s OF
HEALTH SYSTEM ARCHITECTURE,
CAPITAL EQUIPMENT, CONSTRUCTION,
AND ENGINEERING EXECUTIVES
By John R. Fischer
Researchers at the Institut Curie in Or- at once to a single participant in a short during flash therapy helps reduce damage
say, France made history in 2014 when sequence,” Dr. Vincent Favaudon, the incurred by healthy tissue surrounding the
they performed the first demonstration developer of the technique at the Institut tumor. Treating cancer this way, whether it
of flash radiotherapy, a technique that Curie, told HCB News. be a single session or multiple sessions, is ex-
delivers large doses of radiation in a Since then, flash demonstrations have pected to have a dramatic impact on patient
fraction of a second. Applying short pulses been conducted throughout Europe and outcomes and also hospital throughput.
of radiation to the thorax of mice at a dose the U.S., with researchers aiming to adapt “The dilemma in many cases is that the
rate of more than 40 Gy/s, the team exam- the practice for clinical use and improve the tumors are not physically separate from
ined the extent of lung fibrogenesis in the speed and safety of radiotherapy. To do this, certain, critical normal organs. They are
specimen for up to six months after radia- however, requires a thorough understanding sort of ‘weaved’ in,” said Dr. Billy Loo, a
tion, and found that normal, healthy tissue of flash, as well as answers to unanswered professor of radiation oncology at Stan-
sustained less damage, compared to that of questions around its use and impact. ford University. “Even if you’re sculpting
mice irradiated at a conventional dose rate. the dose very carefully, you’re ultimately
“We use a single dose treatment, Sculpting dose and sparing tissue going to be limited in how much radiation
meaning that the entire treatment is given The speed at which doses are delivered you can apply because the normal tissues
avantehs.com/ultrasound
Billy Loo
A long road ahead “Cost of technology has to be reduced
Despite the potential benefits of flash thera- and designed for better economy, compact-
py, important questions remain unanswered ness and compatibility with available infra-
and technological advancements will be structures so you don’t have to build new
necessary. buildings just to put in a machine,” said Loo.
While preclinical research is a good start- “There needs to be better automation and
ing point, Dr. Hans Langendijk, professor clinical efficiency so that more patients can
and chair of the department of radiation be treated on any given system in any given
oncology at the University Medical Center amount of time.”
in Groningen in the Netherlands, cautions From there a host of new questions open
that it lacks essential information in a num- up, such as how to train medical personnel
ber of its findings. The most important of on using the technology and how to ensure
these critiques, he said, includes the need patient access to the treatment, which will
for radio-biological experiments to confirm depend on health policies, healthcare sys-
that first results can be replicated under dif- tems and local politics of individual countries
ferent circumstances, and assessments of and insurance companies.
potential late-term outcomes.
Vincent Favaudon “What we see in radiation therapy is One step at a time
acute toxicities that may occur during the While flash may be years away from be-
course of radiation and immediately after ing used on patients in everyday settings,
radiation,” he said. “Most of these studies a great amount of progress has been made
have been focusing on those complications, around it, including the introduction of clini-
but the mechanisms that may result in late cal trials for humans.
complications — which, in some cases, may “If successful, we could treat patients in
occur even 10-15 years after — are com- a fraction of a second, instead of in seven
pletely unknown.” weeks, with less radiation-induced com-
Fractionation is another area where Lan- plications, and with a very high probability
gendijk said work needs to be done. to obtain tumor control,” said Langendijk.
“The first question is IF we have to frac- “This may be one of the most exciting de-
tionate or not. The second issue is when velopments I’ve seen in my career.”
you give the entire treatment in just a frac- The aim behind flash therapy is not
tion of a second, you have to be very sure just to enhance treatment efficiency but
that the dose delivery is correct, which re- access at lower costs, according to Loo.
quires intense physics quality assurance.” “Our goal is to develop technology to al-
Zeljko Bringing flash to the clinic will also re- low flash ultimately to be used in place of
Vujaskovic quire better equipment because existing existing radiotherapy, enabling it to bring
linear accelerators are incapable of deliver- down price and open up greater access to
ing radiation doses at the required speed. lifesaving treatments for patients.”
Loo and his colleagues at Stanford are Those are big goals, and achieving
working to change this by partnering with them will require the accumulation of
the SLAC National Accelerator Laboratory evidence to illustrate its benefits. On this
in an ongoing program called PHASER, front, there is still a tremendous amount
which incorporates multiple technological of work to be done.
advantages aimed at delivering ultrafast “I am optimistic, and do believe flash
radiation treatment. will find a role in radiation oncology,” said
Developing the technology to deliver Vujaskovic. “It will be a major step forward
flash is itself a two-fold challenge. Making in how radiation is delivered, but again, we
those capabilities viable for actual health- need to have more solid, firm data to move
care providers means that financial consid- this to become a standard of care.”
erations must also be made. Share this story: dotmed.com/news/48319
Addressing gender
disparities in the
field of radiation
oncology
Conversations surrounding pervasive inequities in all aspects Yet, other high-impact studies led by Dr. Reshma Jagsi and col-
of the workforce are now having their long overdue moment leagues have suggested this may not be the case, since substantial
in the spotlight of American society, and healthcare is no unexplained salary gaps have been proved to persist even after ad-
exception. justing for specialty, academic productivity, and work hours.
Paradoxically, perhaps because the field of medicine attracts Within the field of radiation oncology, gender has been shown
a select group of forward-thinking, emotionally intelligent, and to influence many aspects of a physician’s career, including oppor-
logical people motivated to help others, many have been lulled into tunities for academic advancement, scholarly activity, invitations to
believing that gender disparity in medicine does not exist, or when participate in scientific panels, funding for physician researchers, and
it does, it exists for purely rational reasons. For example, while nu- even disease sites treated.
merous studies have described the trend of men earning more than As a new trainee in radiation oncology who has always had an
women at many stages of their careers, these differences are often interest in understanding and mitigating inequities as they manifest
attributed to different career choices made by men and women in in healthcare, I was curious as to how gender might be influenc-
medicine, including the decision to enter less remunerative special- ing salary and clinical activities in our field. Shortly after starting
ties and work fewer hours. residency at the University of California Los Angeles, I sought out
sexual discrimination leading to fewer referrals from surgical and oncologists in our field are male, decreased seniority in practice
medical oncologists. It is also possible that in designing their clinic hierarchies could be resulting in fewer lucrative referral patterns
schedules, women prioritize time spent with a given patient over for the less senior female radiation oncologists.
number of patients seen, and that prioritizing quality over quantity In order to help distinguish amongst these potential etiologies,
results in fewer claim submissions to Medicare. And finally, there we plan to look at the claims submitted by men and women over
may be less billing support in practices attracting female providers, this same time period to determine if there is a difference in the
thereby resulting in a failure to capture services that are actually types of services that men and women bill for. We also plan to dig
being provided. a little bit deeper into the population of physicians who collect the
In terms of reimbursement, decreased collections for women most Medicare dollars to see if we can learn anything about how
might be the natural consequence of gender-related decreases billing patterns differ between men and women among those col-
in clinical activity described above. However, decreased volume lecting the highest reimbursements from Medicare. The answers to
of claim submission alone is insufficient to explain the gap in some of these questions will be presented at our society’s annual
reimbursement, particularly when you consider our finding that meeting (ASTRO) later this year in Chicago.
women also collect less per charge despite the fact that Medicare There are a number of action items for healthcare executives
and administrators looking for ways to mitigate this disparity.
Ensuring that adequate billing support is available to all providers
A more complex yet critical challenge is key, as is assuring that there are no significant imbalances in
referral networks. These are relatively quick and easy interven-
is cultivating a workforce culture tions that can make an impact while efforts continue to pinpoint
the source of the variation. A more complex yet critical challenge
where women are perceived as key is cultivating a workforce culture where women are perceived as
key members of the treatment team and valued as equals, as this
members of the treatment team and will help mitigate disparities both within economic reimburse-
ment and beyond.
valued as equals, as this will help It is our hope that these next steps will move us closer to un-
derstanding and deconstructing sex-based barriers for economic
mitigate disparities both within advancement within the specialty of radiation oncology and we look
forward to making important strides in this direction.
economic reimbursement and beyond. We would like to acknowledge the expertise and input of the
other co-authors on this study, including Julius Weng, M.D.; Reshma
Jagsi, M.D. DPhil; Fang-I Chu, Ph.D.; Sumayya Ahmad, M.D.; and
Michael Steinberg, M.D.
reimburses male and female providers at the same rates. This is About the authors:
likely due to women submitting different kinds of codes than Luca Valle, M.D., is
men, and the codes women submit are likely less well-remuner- in his second year of
ated. Many female radiation oncologists, perhaps for reasons training as a radiation
of mentorship and patient demographics, elect to treat breast oncology resident at
and gynecologic malignancies, and both of these subfields of UCLA. His research fo-
radiation oncology rely primarily on 3D conformal technologies cuses on health policy,
and brachytherapy techniques that are on the lower end of the healthcare dispari-
reimbursement spectrum in terms of planning and delivery codes. ties, and health services. He is a graduate of Dartmouth Medical
Additionally, value-driven management decisions based on the School and is a member of the American Society for Radiation
communal attributes socialized into women (versus the agentic Oncology. Ann Raldow, M.D., MPH, is an assistant professor in the
attributes socialized into men) could partially explain a payment Department of Radiation Oncology at the David Geffen School
differential. For example, when two equivalent treatment options of Medicine at UCLA. She also is a member of the UCLA Jonsson
are available, it is possible that female radiation oncologists are Comprehensive Cancer Center’s Cancer Control and Survivorship
more likely to select the more cost-effective option. We have Program. Dr. Raldow’s research focuses on therapeutic decision
seen this in other specialties, where women have been shown to making, cost-effective care, quality of life and health outcomes
adhere more closely to clinical guidelines, forego costly interven- assessments.
tions, and engage in shared-decision making with patients more Share this story: dotmed.com/news/48320
frequently. And finally, since many of the most senior radiation
Q&A with
Dr. Parag Parikh
director of MR-Guided Radiation Therapy and
director of GI Radiation Oncology
Henry Ford Cancer Institute
Discussing the value of MR-guided
radiotherapy
By Gus Iversen
Last November, Dr. Parag Parikh, joined waitlist for the ViewRay and we have dou- survival in patients who received high-dose
the radiation oncology department at bled our therapy staff to support this. MR-guided radiation therapy to the pan-
Henry Ford Cancer to lead its MR-guided creas, as compared with standard dose ra-
radiation program. HealthCare Business HCB News: We’ve been hearing a lot diation. This is the only study using ablative
News sat down with him to find out how recently about the cutting-edge capabili- doses of radiation given over 5 fractions, and
the new role is working out and why he feels ties of MR-guided radiation therapy. This has a goal of recruiting 133 patients.
that MR-guided radiation is such a promising is a field where Henry Ford is at the cut- We also have a study using 5 fractions of
field for the future of cancer treatment. ting edge. What kind of research are you radiation to treat prostate cancer, using the
currently conducting with these tools? MRI to help boost the dose of the dominant
HCB News: Can you tell us a bit about
your background in radiation oncology
and what it’s been like to join the team
at Henry Ford?
With the advent of the alternative payment model,
Dr. Parag Parikh: I attended medical
school and residency at Washington Univer-
essentially capitating both professional and
sity in St. Louis. I had an early interest in tech-
nology development for tracking moving
technical charges per diagnosis in 90 day events,
tumors and worked under Dr. Daniel Low
to investigate CT scanning of lung tumor
there is an incentive for improvement in outcomes
respiratory motion and implantable electro-
magnetic transponders that could be put
without increasing number of treatments.
into the lung to help guide radiation therapy.
I continued as a faculty member at Wash-
MR-guided radiation therapy machines are uniquely
ington University for 12 years, and our team
treated the first MR-guided radiation ther-
positioned to do this, allowing safe, effective
apy patient in the world in 2014. With the
novel adaptive MR-guided radiation therapy
treatments in one week or less for many diseases
trial by Drs. Lauren Henke and Jeff Olsen, we
realized that abdominal radiation therapy
traditionally treated over 5.5 weeks.
would never be the same.
I returned home to Detroit to join Henry PP: We have several ongoing clinical tri- nodule of prostate cancer in each patient.
Ford in 2018. As the group with the longest- als. First, we are leading the national SMART Finally, we have a corollary study for brain
running clinical MR-linear accelerator pro- study [NCT NCT03621644]. This study builds tumor patients looking at new imaging in-
gram, it was like jumping into a well-running upon retrospective data (Rudra, Cancer Med- formation that may inform how or when to
automobile. We now have a one-month icine, 2019) showing an almost doubling of change radiation therapy for glioblastoma.
HCB News: The MR environment has almost all of the sites, it has certainly become clinical efficacy with heightened efficiency.
unique shielding and safety demands. Is the standard of care for hepatobiliary cancers, With the advent of the alternative payment
the same true for MR-guided radiation as well as small amounts of lymph node dis- model, essentially capitating both profes-
therapy? If so, what kind of strategies ease in the abdomen or pelvis. The ability to sional and technical charges per diagnosis in
are being used to make sure staff follow visualize these tumors, control for respiratory 90 day events, there is an incentive for im-
protocols? motion and change the radiation plan based provement in outcomes without increasing
PP: The MR environment is new to most on stomach and intestine position allow safer number of treatments. MR-guided radiation
radiation oncology departments and we and faster ablative radiation doses. therapy machines are uniquely positioned to
worked hand-in-hand with our radiology The current reimbursement for MR-guid- do this, allowing safe, effective treatments
colleagues to implement best practices for ed adaptive radiation therapy is favorable. in one week or less for many diseases tra-
MR safety. We are included in the hospital- We will obtain reimbursement for additional ditionally treated over 5 ½ weeks. More-
wide MR safety conferences and we also had radiation therapy plans delivered during the over, some users are using their systems to
our staff take the same training as offered radiation course if the anatomy changes in a do away with traditional simulation, which
to radiology staff. A robust safety culture meaningful fashion and these charges have will shorten treatment times further and im-
has prevented any MR safety-related events almost universally been accepted. prove value for the patient. I see MR-guided
in the two years our center has been open. radiation therapy becoming a standard ma-
HCB News: Looking ahead, what role chine in any dual linear accelerator clinic.
HCB News: Is MR-guided radiation do you imagine MR-guided radiation Challenges being addressed currently are
therapy still primarily in the research therapy playing in cancer treatment a treatment times, distribution of adaptive ra-
phase or is it being used more clinically decade from now? What challenges (in diation responsibilities to therapists from the
for certain indications? What is the reim- terms of cost, access, illustrating ben- physician/physicists, and physician training.
bursement situation like? efits, etc.) need to be addressed? For a technology that is less than five years
PP: There are now over 20 programs offer- PP: The long-term radiation therapy old, these steps are occurring rapidly.
ing clinical MR-guided radiation therapy. For practice will need to show simultaneous Share this story: dotmed.com/news/48321
Q&A with
Dr. Theodore
DeWeese
ASTRO president
Raising the profile of radiation oncology
By Sean Ruck
The 2019 American Society for Radia- my heart was — around the notion of help- I also would link that emphasis directly
tion Oncology (ASTRO) Annual Meet- ing those who need it, and I have this great with support for the research mission ASTRO
ing takes place this year from Septem- interest and love of science and biomedi- provides in order to move the field forward,
ber 15th through the 18th at McCormick cine — what better place to do that than and to make sure our newest members in-
Place West in Chicago. HealthCare Busi- in medicine? No one in my family had ever herit a thriving and dynamic field that con-
ness News spoke with ASTRO president, Dr. been to college, much less medical school, tinues to be centered on our patients.
Theodore DeWeese, vice dean for the Johns so I rolled the dice and actually was admit-
Hopkins School of Medicine and the Sidney ted into medical school. All these years later, HCB News: What are the biggest chal-
Kimmel Professor in the Department of Ra- I have loved every moment. lenges facing ASTRO members today?
diation Oncology and Molecular Radiation TD: I think the restrictive coverage poli-
Sciences at Johns Hopkins University, to learn HCB News: What is on your agenda cies that payors have is a real issue for us
about his background and to get an update as president of ASTRO? and our patients. It is frequently a challenge
on the organization. TD: Broadly, there are two categories. obtaining prior authorization for treatment,
First, we want to engage all of our mem- which is associated with a large administra-
HCB News: What inspired you to get bers and support them in their role in caring tive burden and cost. ASTRO has done some
involved in healthcare? for patients with cancer. It means having to work recently evaluating this topic across our
Dr. Theodore DeWeese: When I was in fully educate the public and other physicians membership. It’s been very clear that nearly
college, I came to realize just how much I loved about the unique role that radiation oncol- uniformly — over 90 percent of our mem-
science in the broadest sense, meaning chem- ogy plays within the oncology care team bers have said — patients have been delayed
istry and biology and physics. I was very lucky – particularly, that we are one of the most in receiving radiation therapy because of re-
to have an opportunity to work in a laboratory effective modalities to cure patients. strictive prior authorization practices that are
in the School of Medicine in Colorado. I didn’t There are very high demands for quality employed by many insurers. When a patient
know at the time, but I was doing what we and safety that come with the work we do. has a life-threatening illness, the associated
would now term “translational research”. We That’s very important for the broader audi- threat with delaying their care is just not a
were developing an assay for a particular rare ence to understand our role as oncologists, healthy situation to be in whatsoever.
disease and came up with a way to do that, and is really key in all of this, so we want to As it turns out, about two-thirds of those
and then had an FDA-approved product. As propagate a very clear and positive message denials that originally come from these prior
my first research project, and since I had no about those aspects of who we are. authorizations are overturned anyway. So
framework, I just thought it was the coolest The second is the continuous learning re- it’s a process that’s stressful, potentially risky
thing ever and I had no idea what a rare op- quired of those of us in cancer, generally, and for the patient, and extremely expensive
portunity that was for me. radiation oncology, specifically, because it’s and problematic for the healthcare team.
I also have always loved people and vol- a fast-moving field. We need to make sure Most management of patients today is
unteering and did that in various ways in our members feel they are as contemporary multi-modality, for example, chemotherapy
college and with a variety of organizations in in their knowledge as possible in areas like plus radiation. These treatments have to
Denver. The linkage of those two things, and biomarker development, cancer genetics be sequenced very accurately, and when
really the second in particular, that’s where and immunotherapy linkages with radiation. there’s a delay in either side of that, it can
Hitachi — Booth 1039 accelerators, CT Scanners, PET/CT, MRI systems and more. As dedi-
Hitachi provides flexible particle therapy solutions from single com- cated partners, we offer start-to-finish solutions and a full range of
pact room to multi-room solution. Hitachi also offers proton, heavy- equipment related services including installation, parts support and
ion particles and hybrid (proton + carbon) solutions. Hitachi is a pio- warranty. Far too many people around the world don’t have access
neer in the spot scanning technology for particle therapy. Our state of to the medical treatment and services they need. At ROS, we believe
the art system have been selected and demonstrated by prestigious we can change that. We can extend the life of valuable medical
users worldwide. For more information, please visit Hitachi booth at equipment without compromising safety, quality or environmental
ASTRO 2019. sustainability. We can help hospitals and clinics use their resources
more efficiently, make their budgets go further, and provide more
IBA — Booth 3028 services to their patients.
IBA will showcase the latest innovative technologies coming to
proton therapy with a focus on Motion Management, Proton Arc Sun Nuclear — Booths 2624 & 3415
Therapy and Proton Flash Therapy. These topics will be presented at Sun Nuclear provides innovative QA solutions for Radiation Ther-
our booth 3028 by our team of experts as well as at the IBA Proton apy, Patient Alignment, and Diagnostic Imaging. Our mission is to
Therapy Conference. enable healthier lives by improving the avoidance, detection and
Following its open integration approach, IBA will also showcase treatment of cancer. More than 5,000 cancer centers rely on us
multiple workflows to integrate proton therapy in the clinic with its for independent, integrated Quality Management. With a focus
partners Elekta, Philips and RaySearch. on support, we aim to ease technology adoption, improve out-
Do not hesitate to book a demo at https://radiation-oncology. comes and enhance workflows — so that healthcare providers can
iba-events.com or visit us at booth 3028. achieve real results for Patient Safety. Visit us in Booths 2624 and
3415 for product demonstrations and in-booth talks. Learn more:
Mobius Imaging — Booth 4638 sunnuclear.com/astro.
Mobius Imaging is the premier developer and supplier of Airo®
TruCT, the largest inner bore mobile diagnostic and intraoperative CT Varian — Booth 1405
imaging system. The company will be providing live product demon- At Varian, we envision a world without fear of cancer. For more than
strations of the Airo, booth #4638, at ASTRO 2019. Attendees will 70 years, we have developed, built and delivered innovative cancer
be able to observe Airo mobility, receive a hands-on demonstration of care technologies and solutions to help clinical partners around the
Airo operation, see Airo image quality, and learn more about its appli- globe treat millions of patients each year. We are harnessing ad-
cations in Radiation Therapy through in-booth media presentations. vanced technologies like artificial intelligence, machine learning and
data analytics to advance cancer treatment and expand access to care
Radiology Oncology Systems — Booth 4045 for patients globally. We call our approach Intelligent Cancer Care.
ROS is a global provider of pre-owned radiation therapy and diag- Please visit us in booth #1405 to experience firsthand our evolving
nostic imaging equipment, accessories, and parts including linear ecosystem of technologies for fighting cancer.
ASTRO News
CDR Systems — Booth 1445 “One of the four treatment rooms in our current center is IMPT
CDR Systems, a global patient positioning and immobilization solu- capable and is in very high demand by our patients and physicians.
tions provider introduces the PowerWEDGE™ for Radiation Therapy. Proton therapy expansion at M.D. Anderson will greatly increase
Calgary, AB CDR Systems launches the PowerWEDGE™ specifi- patient access to IMPT, as all four treatment rooms in the new center
cally designed to improve the experience for patients that struggle will be equipped with this advanced technology, more than doubling
with lying flat on their back, the most common treatment position for our current IMPT capacity,” said Gunn. “The new center will feature
the treatment of cancer using external beam radiation therapy. The numerous technical advancements that will further improve proton
PowerWEDGE™ provides an angulation option for patient immo- therapy delivery and precision, such as in-room CT volumetric imag-
bilization that previously could only be offered in a lay flat position. ing and tumor motion tracking.”
This new all-in-one medical device is designed to enhance patient The center experienced a nearly 11 percent increase from 2017 to
comfort and setup accuracy through improved comfort and is offered 2018 in the number of patients who underwent proton therapy. The
with 8 additional module attachments ensuring patient setup can expansion of the 73,500-square-foot facility is expected to provide
be tailored for a wide range of treatment needs, including: cranial more accessibility to patients who would benefit greatly from PT. This
stereotactic (SRS), Body Stereotactic (SBRT), head and neck, breast, includes those with cancer of the head and neck, which currently
lung, liver, spine or pelvic treatments. make up 38 percent of the cases at M.D. Anderson; prostate, lung,
“It is clear a significant subset of the patient population struggle liver, and brain, and a range of pediatric cancers.
to lay in a flat position and a solution that upholds inter and intra The expansion is estimated to be completed by November 2023.
patient positioning accuracy without compromising comfort was Construction will be carried out by Gilbane Building Company.
needed. We have created the PowerWEDGE to answer just that. Carl
Denis, CEO at CDR Systems. Varian — Booth 1405
For an introduction to CDR Systems: At Varian, we envision a world without fear of cancer. For more
• Booth# 1445 at the ASTRO 2019 Annual Meeting, September 15 than 70 years, we have developed, built and delivered innovative
- 17, 2019 McCormick Place West Chicago, IL. cancer care technologies and solutions to help clinical partners
• Schedule a collaborative in person demonstration with a CDR prod- around the globe treat millions of patients each year. We are har-
uct specialist right in your radiotherapy department. nessing advanced technologies like artificial intelligence, machine
• Web based eDemo hosted by a CDR Product Specialist streamed learning and data analytics to advance cancer treatment and ex-
right to your conference room, tablet or personal computer. pand access to care for patients globally. We call our approach
• Toll Free: +1-855-856-7035 or www.cdrsys.ca Intelligent Cancer Care.
During ASTRO 2019, Varian will share a new comprehensive
Hitachi — Booth 1039 adaptive solution that harnesses the power of artificial intelligence.
The University of Texas M.D. Anderson Cancer Center has revealed It’s an AI-driven adaptive solution that includes treatment planning,
plans to more than double the size of its proton therapy center. delivery, and monitoring to fuel the next generation of adaptive
The $159 million project will expand the building to more than therapy. Varian’s Adaptive Intelligence solution is designed to
160,000 square feet, enabling it to take in more patients who require deliver high-quality treatments and incorporate diagnostic quality
treatment with the advanced form of radiotherapy. MR, PET, and CT images during planning and treatment—enabling
“We are excited to more than double our IMPT capacity in the the physician to choose the imaging appropriate for the cancer and
new center to approximate 100 patient treatments per day, better tumor type. Varian’s Adaptive Intelligence solution will empower
ensuring timely patient access so that more patients can benefit from clinical teams to treat more precisely, so they can provide personal-
this technology,” G. Brandon Gunn, associate medical director of ized, optimized care for patients. Please visit us in booth #1405 to
the Proton Therapy Center at the University of Texas M.D. Anderson experience firsthand our evolving ecosystem of technologies for
Cancer Center, told HCB News. fighting cancer.
The expansion will include eight radiation therapy systems devel-
oped by Hitachi that rotate at 360 degrees around patients to deliver Leaders in radiation oncology awarded ASTRO
therapy to the exact area that requires treatment, a technique known Fellow designation
as intensity-modulated proton therapy. The American Society for Radiation Oncology (ASTRO) has selected
The center will also install an additional synchrotron, the accelera- 26 distinguished members to receive the ASTRO Fellow (FASTRO)
tor used to create proton beams, and rooms with improved, modern designation. The 2019 class of Fellows will be recognized in Septem-
designs for better patient experiences. ber during ASTRO’s 61st Annual Meeting in Chicago.
SHOWCASE QLRAD s RectalPro75 lowers toxicity, is patient friendly due to the anatomical shape
and is caregiver friendly. Immobilizes the prostate, reduces movement to have a
better day to day reproducibility due to a symmetrical balloon as well and spread
the rectum to be in low dose area.
TCUDORP
and the concrete cost to the building. Compared with our past layout, Hitachi has
minimized and optimized the configuration yet utilized the identical gantry and ac-
celerator technology which has been proven with our multi-room solution.
ESACWOHS
The combination of Hitachi’s 360 degrees compact rotating gantry and 30 x 40
cm irradiation field size enables users to widely treat many tumor sites. In addition,
Hitachi’s spot scanning technology allows Intensity Modulated Proton Therapy
(IMPT) under fully-integrated Image guidance with gantry mounted isocentric
CBCT. Our system is capable of interfacing with any motion management solu-
tions, treatment planning system and oncology information system.
Airo® TruCT
Mobius Imaging — Booth 4638
Airo® TruCT is a 32 slice, mobile, larg-
est inner bore CT system which provides
intra-procedural diagnostic imaging for
applications in radiation therapy including
Proton Therapy and brachytherapy. Devel-
oped by Mobius Imaging, which special-
izes in standing diagnostic, interventional,
and intraoperative CT imaging systems,
Airo’s Point-of-Care CT imaging may re-
duce procedural time and help increase
treatment accuracy.
PROTEUS®ONE
IBA — Booth 3028
IBA PROTEUS® family is the proton therapy platform of the future
with a comprehensive set of tools for motion management, with
a demonstrated spot-scanning proton arc therapy irradiation, and
finally, with an ultra high-dose rate capability for flash research.
PROTEUS®ONE is the only compact single-room image-guided
IMPT solution, allowing easy integration into a variety of healthcare
settings. Smaller and more affordable than conventional multi-
room proton systems, but with the same clinical applications.
PROTEUS®PLUS
IBA — Booth 3028
IBA PROTEUS® family is the proton therapy platform of the
future with a comprehensive set of tools for motion manage-
ment, with a demonstrated spot-scanning proton arc therapy
irradiation, and finally, with an ultra high-dose rate capability
for flash research.
PROTEUS®PLUS is a multi-room proton therapy solution with
the latest advances in precise, image-guided and intensity mod-
ulated proton beam delivery.
1. Arc therapy is work in progress and Flash therapy is currently under research. Both are not available for sale.
IBA | 2000 Edmund Halley Drive, Suite 210 | Reston, VA 90191 | 571.449.4992 | www.iba-worldwide.com
Latest And Greatest
py, delivering the beam continuously as the
gantry is rotating.
“In classic proton therapy you deliver
the beam from two to up to four angles,”
Genin said. “Arc proton therapy has three
advantages. It improves the throughput of
the facility, simplifies the treatment work-
flow and has the potential to improve clinical
outcomes for specific cases.”
The company has also successfully dem-
onstrated that its ProteusONE and ProteusP-
LUS are able to deliver Flash irradiation,
which delivers high doses of protons at ultra-
high speeds in less than one second, poten-
ProTom Radiance 330 Treatment Room
tially reducing toxicity in healthy tissue. The
company has launched an advisory board to
chael Tajima, senior director of marketing tion we have developed accessible to any
help with adoption.
at Mevion. oncological center that offers radiotherapy,”
“There’s a lot of research to be done and
The company is also launching a new said P-Cure Chief Executive Officer Michael
IBA is committed to fill that gap,” Genin said.
ceiling-mounted cone beam CT, which is Marash. “This will eventually enable every
now clinically available in Europe and soon cancer patient to obtain the best treatment
Mevion
to be FDA approved, developed by the com- in the field.”
Since last year, two proton therapy centers
pany medPhoton, and it is going to be in- P-Cure’s system is in use at the North-
with Mevion HYPERSCAN technology have
stalling a new Siemens CT on rails at Barnes- western Medical Chicago Proton Center. The
come online clinically — the University of
Jewish Hospital in St. Louis. company is supplying its system to medical
Oklahoma Stephenson Cancer Center and
For patient positioning, the company is centers in the U.K. and China, and is nego-
Maastro, formerly the ZON Proton Therapy
integrating the C-RAD Catalyst system for tiating with other cancer treatment centers
Centre at Maastro Clinic, in the Netherlands.
both surface tracking and gating. It is also and research institutes in Israel and around
The company worked with RaySearch
working to validate three new couch tops the world.
on new RayStation capabilities to enhance
and launch them this year.
Adaptive Aperture.
“Now it can shape apertures at any en-
“We’re excited to be providing a suite of ProTom International
new (image-guided radiation therapy) solu- ProTom International has been working with
ergy level with more conformality,” said Mi-
tions,” Tajima said. “We’re really trying to its proton therapy partners to make updates
leverage the best in the field.” to its products.
“You’re always looking at ways you
Mevion HYPERSCAN
P-Cure can improve your product,” said Stephen
In July 2019, proton therapy company P- Spotts, chief executive officer of ProTom
Cure, which markets a gantry-less solution International. “A lot of what we work on is
that reduces the installation costs of a proton behind the walls, so to speak.”
therapy center, announced that it had com- At an installation at Massachusetts Gen-
pleted a $15 million series B funding round eral Hospital, where patient treatment is
led by Hong Kong-based Popular Line Medi starting soon, the company is working on a
cal Group Limited. new workflow-driven user interface that is
The financing will help expand P-Cure’s fully integrated into the facility’s own oncol-
development center and production capac- ogy information system called WhiteBoard.
ity in Israel, according to the company. The The center will also have a fully integrated
company plans to establish a training and couch-mounted cone beam CT with an au-
services center for doctors, physicists, and tomatic patient positioner.
technicians in its new research and develop- “With the cone beam CT mounted on
ment center in Shilat. couch and robotic patient positioner you’re
“Completion of the financing round will not moving the patient from the imaging to
enable us to make the smart medical solu- treatment position,” Spotts said.
Varian
In October, Varian introduced its ProBeam
360° proton therapy system. With a 30 per-
cent smaller footprint than the previous sys-
tem, the system increases the affordability of
proton therapy by reducing vault construc-
tion costs by approximately 25 percent and
cutting the construction time to 10 months C
Flash therapy.
CMY
Radiation therapy
Accuray
Accuray has continued to refine the treat-
ment planning optimizer for the CyberKnife
robotic radiation therapy system.
Brainlab
At ASTRO, Brainlab will be showcasing a
new version of its ExacTrac Patient Position
Monitoring system. Called ExacTrac Dynam-
ic, it is a solution for precision radiotherapy
positioning and monitoring that can accom-
modate a wide range of linacs and clinical
workflows. It is not yet FDA cleared.
“Customers are currently buying two or
three different systems for patient monitor-
ing,” said Patrick Murphy, director of the
Accuray CyberKnife VOLO
oncology portfolio at Brainlab. “Now you
Optimizer Conformal Lung
can have one system for cranial radiosurgery
RaySearch
RaySearch
The company is building RayCommand
on its RayStation treat-
ment planning system
and RayCare oncology
information system with a
treatment control system
called RayCommand.
The new system is de-
Brainlab Elements signed to link RayStation
Spine SRS and RayCare and coordi-
nate activities in and be-
tween treatment rooms
consensus guidelines for spine radiosurgery that make it easier to to maximize resource
contour consistently and avoid potential errors during plan creation. utilization and treatment
accuracy. The product is about two years from being released, said
Elekta Bjorn Hårdemark, deputy chief executive officer of RaySearch.
In December 2018, Elekta received FDA 510(k) clearance for its Elekta RayCommand will also lead the way for online adaptive radiation
Unity MR-linac, a high-field magnetic resonance radiation therapy treatments, Hårdemark said.
system, which allows clinicians to see and track soft tissue during “Clinical practice today is to make a plan for the way a patient
radiotherapy treatment. looks several days before the first day of treatment, and deliver that
On the software side, Elekta will also showcase its MOSAIQ Plaza, same plan over several weeks. To deal with patient and tumor chang-
a “formal ecosystem of applications” built around its MOSAIQ on- es, oncologists use margins,” Hårdemark said. “The most modern
cology information system, and that works seamlessly with Elekta’s way to deal with anatomical changes it is online adaptive therapy. We
radiotherapy solutions, said Sukhveer Singh, president of oncology have the software technology to achieve this, but we haven’t connect-
informatics solutions at Elekta. ed that to any treatment room yet. With RayCommand, we could.”
RayCommand would also be vendor neutral.
Elekta MOSAIQ “Varian and Elekta and ViewRay are also working in that direc-
Plaza tion for their respective systems, but we can do it for any system,”
Hårdemark said.
In December of 2018, the company added two machine learning
systems to RayStation. One is used for patient segmentation. In the
U.S., the company was FDA-cleared for using machine learning to
define where the healthy organs are. In other markets, the technol-
ogy was cleared to find where the tumor is.
Machine learning is also Varian Bravos
used for planning. afterloader
“It learns from previous system
MOSAIQ Plaza includes Elekta’s own SmartClinic, which enables examples what a dose distri-
process visualization and automated, streamlined care coordination, bution looks like for particular
and Care Collaboration, which supports tumor boards and multidis- patients,” Hårdemark said.
ciplinary meetings with cross-specialty data visualization; Monaco
HD treatment planning software; IBM Watson for Oncology, which Varian
provides data-driven decision support; and voice automation using In October 2018, Varian un-
Palabra’s voice recognition technology and customizable templates veiled its Bravos afterloader
for patient notes. system for brachytherapy
“The traditional EMRs are designed to be transactional while the treatments, which delivers
value-based oncology needs more evidence-driven and workflow- radiation via tiny radioactive
oriented solutions,” Singh said. “MOSAIQ Plaza enables value-based source placed directly into
oncology with a portfolio of apps that seamlessly integrate with the tumor. The new device
MOSAIQ as the single source of truth.” improves workflow with a
ViewRay
MRIdian Linac
for the first time to treat patients at Barrow Brain and Spine in Phoe-
nix. A second installation in Beijing is almost complete. The company
is close to applying for a CE mark.
The Zap-X platform has a self-shielding technology, which makes
touchscreen that includes patient and treatment information and a a costly cement radiation vault unnecessary, as well as real-time
customizable pre-treatment checklist, and LED lights to guide clinicians dosimetry.
through the correct connection process of the transfer guide tubes. “One of the ZAP-X’s major attributes is that it allows us to site
“They ensure the right dose is given at the right place, at the right radiosurgery where the patients are, such as ambulatory surgery
time,” said Chris Toth, president of Varian’s Oncology Systems business. centers,” said John Adler, chief executive officer of Zap Surgical.
In April, the company announced it was forming the Adaptive “The idea is to take radiosurgery out of the basement and make it
Intelligence Consortium to research and move forward AI-driven much more available in the world today. Radiosurgery requires what
multimodality adaptive radiotherapy treatments. is arguably the most complex tech in all of healthcare. We are trying
Also this year, Varian acquired Cancer Treatment Services Inter- to remedy that by making a simpler-to-use machine, which at the
national. same time, is also safer.”
The acquisition includes the American Oncology Institute in Hy- Share this story: dotmed.com/news/48323
derabad and 10 multidisciplinary cancer centers across India as well
as a U.S.-based Oncology Solutions division that provides cancer care
professional services to healthcare providers worldwide.
“It gives the company unique access to global cancer data,” Toth
said.
ViewRay
In February 2019, ViewRay received FDA 510(k) clearance to market
the new soft tissue visualization capabilities for its MRIdian Linac sys-
tem, which combines a linear accelerator with an MR scanner, was
cleared by the FDA in February 2017, and has treated approximately
5,000 patients.
Called SmartVISION, the technology doubles the frame rate of the
MR from four frames per second to 8 frames per second.
“Essentially what this does is it gives you better tracking capa-
bilities and more disease-specific imaging capabilities,” said Michael
Saracen, vice president of clinical marketing at ViewRay.
There is also expanded high-definition visualization and enhanced
contrast between different tissues, to assist clinicians with tissue visualiza-
tion and beam contouring, a diffusion-weighted imaging feature that
tracks treatment progress by distinguishing between tumor and normal
tissues, and enhanced MLC speed to potentially reduce treatment time.
“The SmartVISION helps [clinicians] to do what they are doing,
better,” Saracen said.
Zap Surgical
The company received FDA clearance in October 2017 for its Zap-X
stereotactic radiosurgery system. In January of this year it was used
CT dose
How much is just enough?
By John R. Fischer
Ten years ago, radiologists and medi- more discretion when choosing diagnostic imaging,” Dr. Mahadevappa Mahesh,
cal imaging stakeholders received an imaging exams and ensuring providers were ACR Medical Physics Commission chair and
alarming wake up call. A report issued by adequately equipped to determine, deliver chief physicist for Johns Hopkins Hospital,
the National Council of Radiation Protection and monitor the exposure of their patients. told HCB News. “Also, the ACR-DIR data are
and Measurements (NCRP) revealed that the A prime example is the ACR Dose Index facilitating to set national or regional diag-
radiation exposure to the U.S. population Registry (DIR), which many providers rely on nostic reference levels for a variety of CT ex-
from medical procedures had risen dramati- to compare their CT dose data to their peers ams. Recently efforts are underway to roll out
cally over the span of a few decades. locally and nationally. Since 2011, the pro- a dose index registry for fluoroscopy exams.”
This concern around radiation dose gram has amassed nearly 2,200 facilities as But dose registries and improvements to
marked a turning point for the medical im- active participants and contains data from technology don’t resolve radiation exposure
aging industry, paving the way for accredita- more than 81 million CT scans. issues unless providers act on them. That
tion programs and official dose committees, “The information provided helps facilities means taking up the mission of ensuring
as well as the maturation of dose technolo- to examine and review their CT protocols, patients receive the right types of exams
gies and, more broadly, a greater awareness and where necessary, cut down and opti- with just enough dose to obtain a reliable
of dose exposure. New initiatives pushed for mize their techniques for improving their CT diagnostic image.
Injector Support
and misinformation is a fact of life for
many people researching imaging exams
& Service
online. This creates a unique challenge for
providers, who are tasked with articulating
relative pros and cons, as well as sharing
facility details concerning accredited and
quality control programs.
“At the radiation dose levels used for
routine medical imaging such as CT, there
is no good evidence to demonstrate ad-
verse effects,” said Mahesh. “However,
there is confusion about this and depend- Providing professional,
ing on who spins the story, people are timely and superior
often really concerned even with routine
medical imaging.”
support and service
Mahesh is currently involved in a follow- for medical
up to the 2009 NCRP report which is called contrast injectors.
Medical Radiation Exposure of Patients in
the United States, and is expected to be
released in November. The report should
give an indication as to whether or not ef-
forts to reduce dose have had a substantial injectorsupport.com
impact in the last 10 years. 888.667.1062
“From my experience, most imaging
facilities attempt to meet the compliance
of regulatory and accreditation bodies
implementing the standards, whereas oth-
ers strive to reach a balance between dose
and image quality,” said Durairaj. “There
Houston Methodist
Computed Tomography (CT) has trans- While traditional CT is performed using a based imaging modalities, including CT. One
formed medical care worldwide since single peak energy level, spectral (or “dual of the primary advantages of spectral CT is
its development in the 1970s, and the energy”) CT refers to methods that obtain that it allows separation of the total attenu-
technology has advanced considerably information regarding tissue attenuation at ation of the tissue into that which is attribut-
since then, allowing for an ever increas- 2 or more energy levels. Broadly speaking, able to iodine, and that which is attributable
ing number of applications. CT utilizes this may be achieved by either varying the to water (the primary constituent of biologi-
a rotating X-ray tube detector array in or- energy level of the beam generated by the cal tissues) through a process called material
der to generate cross-sectional images of X-ray tube, or by discriminating between the decomposition. This allows quantification
the body, typically utilizing an X-ray beam energies of the incident X- photons at the of iodine content, and generation of iodine
covering a broad energy range, but with a detector. This allows for multiple new types overlays or iodine basis images.
peak energy of 120 kilo-electron volts (120 of images to be generated and multiple new Iodine quantification is an active area
kVp), although this may be higher or lower applications. of research as a quantitative imaging bio-
in certain clinical situations. The image cre- marker, and is being studied as an indicator
ated assigns grayscale values based on the Material density images of treatment response in various cancers,
attenuation of the beam (i.e., how much Iodine has been employed for many decades for example. Additionally, there is a growing
was absorbed or scattered in the patient). as a means to generate contrast in X-ray- body of evidence that iodine images can
BRINGING EXCELLENT
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Dual Energy
help discriminate between benign and po- non-contrast scan followed by a contrast- the liver, both for hypervascular and hypo-
tentially malignant incidental renal masses enhanced scan. This allows the radiologist vascular masses. Additionally, they can be
on routine abdominal contrast enhanced to differentiate between tissues that were used in angiography to enhance vascular
CT’s — a common occurrence. Typically, intrinsically bright on the image prior to con- contrast. This can be leveraged to reduce
these incidental findings would require trast administration from those which be- contrast dose, which can both reduce cost
bringing the patient back for a follow up came bright only after contrast administra- as well as improve patient safety (lower
multiphase scan with and without contrast. tion. However, this comes at extra expense, risk of contrast induced nephropathy), and
With iodine images it is now possible to time, and radiation dose to the patient. can also reduce the need for repeat scans
characterize the majority of these lesions at With spectral CT, once the iodine and wa- due to a suboptimal contrast bolus. CT pul-
the initial scan, saving time, cost, and radia- ter contributions have been decomposed, monary angiography occasionally suffers
tion dose to the patient. virtual unenhanced images can be gener- from transient contrast interruption which
Another area where material decomposi- ated which mimic a non-contrast scan. In can result in a non-diagnostic scan, for ex-
tion is poised to bring value to CT is in bone some applications this virtual unenhanced ample. In these cases patients are often
marrow edema imaging. In this case, calcium image may be able to replace an actual non- re-dosed with contrast and rescanned, re-
sulting in both double the contrast load as
well as double the radiation dose. With vir-
Spectral CT allows separation of the total attenua- tual monoenergetic imaging, lower energy
images can be reconstructed that enhance
tion of the tissue into that which is attributable what contrast there is and can salvage an
otherwise non-diagnostic scan, reducing
to iodine, and that which is attributable to water cost as well as contrast and radiation dose
to the patient.
(the primary constituent of biological tissues) On the other hand, higher energy images
can be generated which reduce metal arti-
through a process called material decomposition. fact, such as in the presence of orthopedic
hardware. This is of significant benefit in the
This allows quantification of iodine content, and evaluation of joint prostheses, where tradi-
tional CT scans suffer from severe artifacts.
generation of iodine overlays or iodine basis images. The difference is so dramatic, in fact, that
in our own institution, many orthopedists
now specifically request scans to be done
with dual energy. We also use higher energy
is used as one of the basis materials, and by contrast scan in multiphase pre- and post- virtual monoenergetic images in addition
removing its contribution to the image, it contrast protocols, saving time, radiation to metal artifact reduction to improve CT
becomes possible to visualize bone marrow dose and cost. myelography in the presence of spinal hard-
edema, which could previously only be done ware, and have not looked back.
with MRI. Although research is ongoing and Virtual monoenergetic imaging
this is still in its infancy, many centers are be- X-ray beams consist of individual photons of Niche applications
ginning to employ it in the clinical routine. varying energy, although with a user selected In addition to the broader applications de-
These are typically performed in the trauma peak energy level (i.e. 120 kVp). This is re- scribed above, there are several niche ap-
setting, such as when evaluating spinal com- ferred to as a polyenergetic or polychromatic plications to be aware of. For one, spectral
pression fractures. Currently, determining the beam. The image generated is therefore a CT allows characterization of kidney stone
acuity of spinal compression fractures at CT composite of all of the different energy X-ray composition, which can affect how they may
can be unreliable, and many patients go on photons contained in the beam. Spectral CT respond to various treatments. This can be
to have an MR, resulting in additional cost allows the generation of virtual monoener- valuable information to the urologist, and
and possibly length of stay. With spectral CT, getic images, as if the beam consisted entire- allow for more expeditious triage to the cor-
it may be possible to answer this question up ly of a single X-ray energy. This can benefit rect treatment. Additionally, through simi-
front, reducing both cost and length of stay. in several ways. lar techniques, spectral CT can be used to
Lower energy images can be generated detect gout tophi. In fact, spectral CT is al-
Virtual unenhanced (aka “virtual that enhance the appearance of iodinated ready included as a criterion for establishing
non-contrast”) imaging contrast. These have been shown in multi- a diagnosis of gout, and can also be used to
Many scan protocols call for an initial ple studies to improve lesion conspicuity in monitor patients who are on therapy.
Q&A with
John Boone
professor of radiology and biomedical
engineering, and chief of medical physics
University of California Davis
Ultrahigh-res scanning comes to CT
By Gus Iversen
If you’re a regular reader of HealthCare ment, I saw the opportunity for my young with imaging matrices of 512 x 512, 1024 x
Business News magazine, the name academic radiologist colleagues to have an 1024, and 2048 x 2048. The MTF, which is
John Boone might be familiar to you. A opportunity to evaluate and report on this the traditional measure of spatial resolution
couple of years ago we sat down with him technology in a series of clinical protocols in imaging systems, has a limiting resolution
to talk about a novel breast scanning CT sys- spanning applications from neuroradiology for clinical operation on the order of 3.2 pairs
tem he developed alongside colleagues at to musculoskeletal radiology — and that per millimeter, which is consistent with the
UC Davis. We recently reached out to him was the primary motivating factor for me 150 µm voxel dimensions.
again to discuss another CT innovation — in this project.
ultrahigh-resolution. This CT scanner (which is now the Can- HCB News: What does ultrahigh-res
Boone is a researcher, educator, and on Aquilion Precision) has high-resolution mean in terms of CT scan image quality?
clinical medical physicist with long-stand- features, which, in my opinion as a medi- Does it open up new capabilities?
ing interests in CT technology. He is former cal physicist specialized in CT technology JB: We are all aware of the various mo-
president of the American Association of are a game changer for CT imaging — per- dalities available in the radiology department
Physicists in Medicine (AAPM), and cur- haps not for every CT examination, but for for imaging patients and, of course, each of
rently chairs the CT subcommittee for this a number of imaging applications I believe these modalities has its strengths and weak-
organization. He is also the primary author the high-resolution capabilities will lead to nesses. Traditional resolution CT imaging
of the ICRU (International Commission on more accurate diagnoses and better patient excels at contrast resolution (the ability to
Radiation Units) Report 87, “Patient dose care. The system has a 40 mm-wide detector see large lesions with subtle contrast differ-
and image quality assessment in computed (measured at the isocenter, per industry stan- ences) but is not particularly exciting when it
tomography”. dards), with 160 – 0.25 mm wide detector comes to spatial resolution (the ability to see
arrays along the long axis of the scanner (the small objects) — which for most clinical CT
HCB News: In April, UC Davis Health Z dimension). There are 4 different acquisi- scanners the smallest resolvable element is
announced that it was performing clini- tion modes, which the manufacturer refers on the order of 0.50 mm. But with this new
cal imaging exams using an ultrahigh- to as normal resolution, high resolution, su- CT scanner, we have the ability to resolve
res CT scanner. Can you tell us a bit per high-resolution, and ultrahigh-resolution 0.15 mm voxels; and the obvious question is,
about the technology and how it came modes. Of course, the size of the detector “What human anatomy has spatial features
to be acquired by the facility? elements is not the only resolution-limiting on the scale from 0.15 to 0.5 mm?” The
John Boone: About 2 years ago, I was factor, and this scanner has 7 different focal answer to this is the answer to your question
approached by an executive from (then) spot sizes that can be used, unlike any whole- about “new capabilities”. We believe that
Toshiba, about the potential of siting this body clinical CT scanner I have seen in the the increase in spatial resolution achievable
new high-resolution CT scanner at UC Da- past. Obviously, the smaller focal spots need by this new CT scanner technology will al-
vis. I was immediately excited about the to be used with the higher resolution detec- low meaningful improvement in diagnoses
prospect of evaluating this new technology tor modes to actually achieve high-resolution involving lung parenchyma, the anatomy
— and as a leader in the research adminis- images. The system is capable of reconstruct- of trabecular bone (in trauma and disease),
tration of my academic radiology depart- ing images with 0.15 mm pixel dimensions, liver texture, and microvasculature — the
Carestream's
OnSight 3D
Extremity System
“We are able to handle much smaller pieces of metal and bigger
pieces of metal such as knee implants,” said David Chan, regional
business director for the U.S. and Canada for Carestream. “They can
Canon AiCE 1
see micro fractures or signs of infection.”
The scanner allows imaging from the distal femur to the toes with
Canon Medical Systems and without weight bearing, and the distal humerus to the fingertips,
In June of this year, Canon Medical Systems received FDA clearance allowing surgeons to have a better image of the problem before a
for its Advanced Intelligent Clear-IQ Engine (AiCE), which uses a deep procedure. The systems are designed for sports medicine facilities.
learning algorithm to differentiate signal from noise in CT images, so Carestream is next tackling deep learning to improve image qual-
noise is suppressed while signal is enhanced. ity as well as the validation of 3D measurements.
“It makes it easier for the physician to read and have a natural tex- “Now, weight-bearing measurements are done on 2D projection
ture for the image,” said Tim Nicholson, senior marketing manager radiography,” Chan said. “We’re leveraging some of these devel-
for Canon Medical Systems. “With the (previous) dose reduction, you opments into 3D measurements and validating their accuracy and
gave up texture. With this type of reconstruction using deep learning, validity in a working group.”
it really brings that image quality up another step and it can go a step
further in lowering the dose because there’s less noise in the image.” CurveBeam
AiCE is available on new purchases of Canon’s Aquilion ONE / Since receiving FDA clearance for its LineUP bilateral weight-bearing
GENESIS Edition, released three years ago, and the Aquilion Precision CT imaging system for the knees and lower extremities, in May 2018,
platforms, released in April 2018. The company plans to eventually CurveBeam is developing an upgrade that will extend imaging capa-
make AiCE available on new mid-tier scanners. bilities up to the hips.
“We believe our deep learning reconstruction will be superb be- “The body would be slightly modified so that the gantry could
cause it’s fast enough to use on every single exam,” Nicholson said. raise higher,” said Vinti Singh, marketing manager for CurveBeam.
“We have quantifiable claims we used in our FDA submission on “The capability to scan up to the hip is essential for preoperative
noise reduction and low-contrast detectability.” planning for knee replacement surgery because the hip is a required
anatomical reference point.”
Carestream The key features of the device, including a compact footprint and
Carestream released its OnSight 3D Extremity System in February the ability to plug into a standard wall outlet, will remain.
2017. Since the release, it has added workflow improvements and “Research demonstrates weight-bearing CT may be instrumental
enhanced metal artifact reduction. in detecting early signs of knee osteoarthritic degeneration,” Singh
FUJIFILM FCT
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iCRco, Inc.
www.icrco.com
26 Coromar Dr. Goleta, CA 93117
(310) 921-9559
iCRco inc.
iCRco inc.’s latest product, the ClarisXT, is
a multi-modality device that provides high-
resolution 3D imaging, as well as full-field di-
agnostic X-ray. ClarisXT replaces a traditional
X-ray system in an orthopedic, sports medi-
cine or medical clinic. The system is designed
for general X-ray applications, orthopedic
imaging, bones and joints, as well as head
and neck studies.
ClarisXT provides four times better reso-
lution than traditional CT, at a third of the
dose, said Stephen Neushul, president, iCRco inc. Claris XT
chief executive officer and head engineer
of iCRco.
Philips
At ECR in March, Philips launched its Incisive
CT, a general purpose 64-slice and 128-slice
scanner.
The 72-centimeter bore “workhorse”
scanner comes with a “Tube for Life” guar-
antee — Philips will replace the new vMRC
for low-dose lung screening that was ap- the American Lung Association, Atrium tube X-ray tube, which the company says is
proved by the FDA in 2018. Health’s Levine Cancer Institute and others. already more reliable, throughout the entire
“Winnebago Specialty Vehicles has a The companies plan to work together to lifespan of the system at no additional cost.
long history of mobile medical care,” said build more mobile screening vehicles. This guarantee has the potential to re-
David Webster, chief executive officer of At RSNA 2018, NeuroLogica launched duce operational expenses by an estimated
NeuroLogica. and its 16-slice, small-bore CT scanner, $400,000.
NeuroLogica and Winnebago Specialty OmniTom. The mobile system can be used “One of the most expensive components
Vehicles division collaborated this summer at the point-of-care in the neuro-ICU and in CT is changing the tube,” said Karim
for the first Mobile Lung Symposium in Min- in the operating room for neurosurgery Boussebaa, business leader for computed
neapolis, Minnesota, hosting speakers from cases and full-body pediatrics. tomography and advanced molecular im-
Siemens Healthineers
At the American College of Cardiology
annual meeting this past March, Siemens
Healthineers debuted the SOMATOM
go.Top Cardiovascular Edition, a new ver-
sion of the 128-slice CT scanner designed
with the necessary hardware and software,
as well as a workflow geared specifically to-
ward cardiac imaging.
The scanner is capable of providing the
high-quality coronary CTA (CCTA) images
required for the HeartFlow FFRCT Analysis,
a cardiac test developed by HeartFlow Inc.,
that enables clinicians to better evaluate the
impact a blockage has on blood flow and
determine the best treatment for patients,
according to the company.
Research has shown that CT for front line
coronary CT imaging has value, said Mat-
Siemens Somatom
thew Dedman, director of marketing for GoTop
CT at Siemens Healthineers North America.
On a day-to-day basis, radiation shield- What information should tor of marketing and IT at NELCO World-
ing is probably not something that is providers share with their wide. “If you’re above a 10 megavolts ma-
on the top of a healthcare provider’s list shielding partners? chine, you’re not just dealing with gamma
of concerns, but these massive projects Shielding a diagnostic imaging facility and but you’re also dealing with neutrons to
are crucial to any facility. Whether it’s an shielding a radiotherapy facility are two shield for.”
imaging department or a radiotherapy treat- completely different tasks. Both require the Because of that, it’s beneficial to engage
ment center, having a basic knowledge of facility to share certain information with the with the company early on in the planning
shielding will help you make sure the right shielding company, but radiotherapy takes phase regarding planning for the space re-
decisions are made when shielding projects things to a whole other level. quirements, the ancillary space around the
or issues arise. A few experts in the field “Radiotherapy is a lot more complicated room and fitting feasibility. All of that can
shared their insight with HCB News on these because you’re dealing with much higher have a large impact on the budget and
matters. levels of radiation,” said Cliff Miller, direc- schedule for completing the project.
“A good shielding design by a qualified logistics, difficulty handing and especially the projecting how the caseload may increase
physicist should occur at the beginning of nature of radiation being shielded.” over the lifetime of the unit before installing
the process,” said Petrone. “An inexperi- For radiotherapy, Veritas usually uses any radiation equipment. By doing that, the
enced physicist may incorrectly calculate the its VeriShield system, which involves dry, initial design will never have to be revisited.
shielding needs and cost you down the line.” stacked shielding modules that interlock to “Most professionals would advise to proj-
form a leak-free therapy room. It’s structural ect the absolute maximum steady state aver-
What about radiotherapy? in terms of load bearing, consistent in com- age workload that would ever be reached
When it comes to radiotherapy, choosing the position, shape and density, uses space ef- during the life of the machine,” said Petrone.
right material isn’t as clean cut. NELCO and ficiently, attenuates a wide range of ionizing Martin agrees that new and/or growing fa-
Veritas don’t have a material of choice be- radiation and is modular in nature to provide cilities should always be looking 10 years down
cause they take into account each project’s design flexibility. the road to anticipate future growth. That can
unique needs. range from considering additional future pa-
“We’ll use a myriad materials to meet Shield for existing or tients in a single space to including extra space
the customer’s needs and budget require- future throughput? adjacent to the current bunker in a design to
ments,” said Miller. “We don’t try to jam a “Some may argue to shield for the existing easily add treatment rooms in the future.
product into every project and just say this is workload and if the workload increases, add “Adding extra layers of material to a
what we have and you live with it.” more shielding,” said Petrone. “Even if this room during initial construction is much
If the customer has space constraints, then would be possible, it is a dangerous selec- more cost-effective than having to add
they may use lead since it has the highest tion, analogous to being penny wise and shielding later,” he said. “Existing facilities
shielding value of any material. In other cases, pound foolish.” with multiple treatment spaces in operation
they may use a combination of lead and con- He added that the likelihood that a facil- are usually adding equipment for more stra-
crete or lead and the high-density concrete. ity will forget to redo their shielding design, tegic reasons and should consider the extra
“As with most things, there is no one- leaves them open to a noncompliance situa- shielding costs in conjunction with their abil-
size-fits-all solution,” said Martin. “The best tion, which could be dangerous for the sur- ity to split additional workload over multiple
shielding material depends on a number of rounding areas. treatment spaces.”
factors including raw material cost, project To prevent all of that, he recommends Share this story: dotmed.com/news/48328
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Future of radiotherapy:
Efficiency and accessibility
By Dr. Deepak “Dee” Khuntia
While the future of radiotherapy will lar basis, clinicians can look at physiological to countries around the world won’t achieve
continuously evolve through the dili- changes (e.g., bladder fluctuations, changes meaningful outcomes. The technology is
gence of passionate physicians and re- in weight, changes in tumor size) in the pa- appreciated, but without the appropriately
searchers, one thing remains constant: tient to account for macro fluctuations in the trained personnel to manage the machines
advancements in radiation oncology tumor’s shape and position due to changes in — which can be sparse in developing coun-
will be designed and developed to al- nearby organs. The approach allows clinicians tries and communities — the ability to treat
low clinicians to put patients’ needs first, to reassess, adjust, and adapt the treatment patients will still be limited. The industry is
always. Two such approaches — adaptive plan. Today, this can be completed for certain being challenged to develop treatment tools
radiotherapy and FLASH therapy — will, patients, but the treatment adjustment process that decrease the time it takes to learn and
when commercialized, prioritize treatment is a lengthy and laborious one. Aggressive and understand the technology. This will stream-
efficiency and accessibility to do just that. innovative work is currently being done to turn line training and ultimately boost access to
this 2 – 3-day long process into a treatment de- care. Knowledge-based learnings tools, or
Where are we today? signed to enable adaptive treatments in a stan- artificial intelligence, has the power to move
We define FLASH therapy as a noninvasive dard radiotherapy timeslot. If we can achieve the needle as well.
treatment that relies on external beam ra- this, the process will be easier on the patient Artificial intelligence tools have been in the
diation delivered in ultra-high doses, at ultra- and clinics will be able to treat more patients in market for several years and, looking ahead,
high speeds (less than one second), typically the abbreviated period of time. The future of the next step is to bring this type of technol-
in one to three sessions. It will empower clini- adaptive radiotherapy leverages artificial intel- ogy into radiation oncology even more. Le-
cians to treat and target cells in seconds, ver- ligence in order to segment and map out the veraging AI to better understand where the
sus minutes. Initial preclinical research on the anatomy, target where the tumor is, and opti- tumor is, which tissue needs to be avoided,
value of ultra-high dose rate FLASH therapy mize quality assurance of the treatment plan. etc., is an example of the near-term applica-
conducted by Varian and two of its clinical tions of intelligent radiation technology.
partners (Maryland Proton Treatment Center Accessibility + intelligent The future of radiotherapy will offer a
and Cincinnati Children’s/UC Health Proton advancement = adoption personalized, flexible, and dynamic long-
Therapy Center), has been promising. To fur- Once these modalities leap relevant regu- term treatment strategy that can offer better
ther study such ultra-high dose rate cancer latory hurdles, treatment and real-world experiences to clinics large and small — and
treatments with protons, the Varian FlashFor- scalability still will be imperative to clinical to patients around the globe.
ward Consortium was announced last year. adoption of these approaches, and the mod- About the author: Deepak “Dee” Khuntia,
If we look at adaptive therapy, it is a treat- ern-day reality is that the time, resources, M.D., is the senior vice president and chief
ment approach that evolves over time in re- and training needed to implement new ap- medical officer at Varian Medical Systems.
sponse to the temporal and spatial variability of proaches also are obstacles. Currently, just Share this story: dotmed.com/news/48329
the patient’s anatomy. On an increasingly regu- “airdropping” linear accelerators (LINACs)
The right product, technology, and equipment in the right place, at the
right time, at the right cost, for the right patient – all day, every day.
It’s not a miracle. It’s great strategy.