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    Kami Export - POGIL 1 DNA Structure

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    Eva Ellis
    DNA contains the genetic blueprint for life. It has a ladder-like structure where nucleotides form the rungs and sugar-phosphate backbones form the sides. The bases of nucleotides on opposite strands bond together following base-pairing rules - adenine pairs with thymine via two hydrogen bonds, and cytosine pairs with guanine via three hydrogen bonds. In reality, the two strands of DNA coil around each other to form a double helix shape.

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    Kami Export - POGIL 1 DNA Structure

    Uploaded by

    Eva Ellis
    167 views2 pages
    DNA contains the genetic blueprint for life. It has a ladder-like structure where nucleotides form the rungs and sugar-phosphate backbones form the sides. The bases of nucleotides on opposite strands bond together following base-pairing rules - adenine pairs with thymine via two hydrogen bonds, and cytosine pairs with guanine via three hydrogen bonds. In reality, the two strands of DNA coil around each other to form a double helix shape.

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    DNA contains the genetic blueprint for life. It has a ladder-like structure where nucleotides form the rungs and sugar-phosphate backbones form the sides. The bases of nucleotides on opposite strands bond together following base-pairing rules - adenine pairs with thymine via two hydrogen bonds, and cytosine pairs with guanine via three hydrogen bonds. In reality, the two strands of DNA coil around each other to form a double helix shape.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    167 views2 pages

    Kami Export - POGIL 1 DNA Structure

    Uploaded by

    Eva Ellis
    DNA contains the genetic blueprint for life. It has a ladder-like structure where nucleotides form the rungs and sugar-phosphate backbones form the sides. The bases of nucleotides on opposite strands bond together following base-pairing rules - adenine pairs with thymine via two hydrogen bonds, and cytosine pairs with guanine via three hydrogen bonds. In reality, the two strands of DNA coil around each other to form a double helix shape.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    of 2

    DNA Structure and Replication

    HOV.' is genetic information stored and copied?

    Deoxyribonucleic acid or DNA is the molecule of heredity. It contains the genetic blueprint for life. For
    organisms to grow and repair damaged cells, each cell must be capable of accurately copying itself. So how
    does die structure of DNA
    allow it to copy itselfso accura

    Model 1 —The Structure of DNA


    Model ofDNA Helix Model ofDNA
    Nucleotide

    C G
    Phosphate

    T A
    D •oxyn%oe Nitrogen-
    sugar contmmng
    base

    A T
    Nitrogen Bases

    G C
    Thymine

    C G
    Guamne

    D Cytosine T A

    l. Refer to the diagram in Model l.

    What are the thlee parts ofa nucleotide?

    Sugar, Phosphate, and Nitrogen Base


    b. What kind of sugar is found in a nucleotide?

    deoxyribose
    c. Which nucleotide. component contains nitrogen?
    bases (a, t, c, g)
    d Name the four nitrogen bases shown in Model l.

    Adenine (A) Thymine (T) Cytosmine (C)


    2. DNA is often drawn in a "ladder model." Locate this drawing in Model l.

    Circle a single nucleotide on each side of the ladder model of DNA


    Look at latter

    DNA Structure and Replication 1


    b. What part(s) ofthe nucleotides make up the rungs of the "ladder"?
    bases
    c. What parts ofthe nucleotides makeup the sides (backbone) of the "ladder"?

    Sugar and phosphate


    d Look at the bottom and top ofthe "ladder" in Model l. Are die rungs parallel (the ends of
    the strands match) or antiparallel (the ends of the strands are opposites)?

    Antiparallel, one side ends in sugar and the other side ends in phosphate
    3. On dae ladder model of DNA label each ofthe bases with the letterA. T, C or G.
    Look at latter
    4. Refer to Model l. When one nucleotide contains adenine, what type of base is the adenine
    attached to on the opposite nucleotide strand?

    Thymine
    5. The two strands of DNA are held together with hydrogen bonds between the nitrogen bases.
    These are weak bonds between polar molecules. How many hydrogen bonds connect the two
    bases from Question 4?

    two
    6. Refer to Model l. When one nucleotide contains cytosine, what type of base is the cytosine
    attached to on the opposite nucleotide strand?
    Guanine
    7. How many hydrogen bonds connect the two bases from Question 6?
    Three
    8. With your group, use a complete sentence to write a rule for how the bases are arranged in the
    laåder model of DNA.

    The Adenine and Thymine bases connect and then Cytosine and Guanine connect

    Read This!
    Elwin Chargaff (1905—2002), an Austrian-American biochemist, investigated the ratio of nucleotide bases
    found in the DNA from a variety of organisms. From his research, as well as reseacch by Rosalind Frank*
    lin and Maurice Wilkins, Watson and Crick developed the oomplementary base-pair rule during their
    race to discover the structure of DNA. The complementuy base-pair rule states that adenine and thymine
    form pairs across two strands, and guanine and cytosine form pairs across tv.'0 strands,

    9. Fill in the complementary bases on the strand below according to the base-pair rule.

    c
    T A G G T C
    10. The ladder model ofDNAis asimplified representation ofthe actual structure and shape ofa
    DNA molecule. In reality, the strands of DNA form a double helix. Refer to the double helix
    diagram in Model I and describe its shape using a complete sentence.

    A double helix is two back bones made of alternating phosphate and sugar. The bases connect
    the back bones in the middle of the double helix.

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