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    B Pharmacy

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    SYLLABUS

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    B Pharmacy

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    srinidhi2all
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    SYLLABUS

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    SYLLABUS

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    47 views2 pages

    B Pharmacy

    Uploaded by

    srinidhi2all
    SYLLABUS

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    of 2

    BP801T.

    BIOSTATISITCS AND RESEARCH METHODOLOGY (Theory)

    45 Hours

    Scope: To understand the applications of Biostatics in Pharmacy. This subject deals with
    descriptive statistics, Graphics, Correlation, Regression, logistic regression Probability
    theory, Sampling technique, Parametric tests, Non Parametric tests, ANOVA,
    Introduction to Design of Experiments, Phases of Clinical trials and Observational and
    Experimental studies, SPSS, R and MINITAB statistical software’s, analyzing the
    statistical data using Excel.

    Objectives: Upon completion of the course the student shall be able to


    • Know the operation of M.S. Excel, SPSS, R and MINITAB®, DoE (Design of
    Experiment)
    • Know the various statistical techniques to solve statistical problems
    • Appreciate statistical techniques in solving the problems.

    Course content:
    Unit-I 10 Hours
    Introduction: Statistics, Biostatistics, Frequency distribution
    Measures of central tendency: Mean, Median, Mode- Pharmaceutical examples
    Measures of dispersion: Dispersion, Range, standard deviation, Pharmaceutical
    problems
    Correlation: Definition, Karl Pearson’s coefficient of correlation, Multiple correlation -
    Pharmaceuticals examples

    Unit-II 10 Hours
    Regression: Curve fitting by the method of least squares, fitting the lines y= a + bx and x
    = a + by, Multiple regression, standard error of regression– Pharmaceutical Examples
    Probability:Definition of probability, Binomial distribution, Normal distribution,
    Poisson’s distribution, properties - problems
    Sample, Population, large sample, small sample, Null hypothesis, alternative hypothesis,
    sampling, essence of sampling, types of sampling, Error-I type, Error-II type, Standard
    error of mean (SEM) - Pharmaceutical examples
    Parametric test: t-test(Sample, Pooled or Unpaired and Paired) , ANOVA, (One way
    and Two way), Least Significance difference

    Unit-III 10 Hours
    Non Parametric tests: Wilcoxon Rank Sum Test, Mann-Whitney U test, Kruskal-Wallis
    test, Friedman Test

    156
    Introduction to Research: Need for research, Need for design of Experiments,
    Experiential Design Technique, plagiarism
    Graphs: Histogram, Pie Chart, Cubic Graph, response surface plot, Counter Plot graph
    Designing the methodology: Sample size determination and Power of a study, Report
    writing and presentation of data, Protocol, Cohorts studies, Observational studies,
    Experimental studies, Designing clinical trial, various phases.

    Unit-IV 8 Hours
    Blocking and confounding system for Two-level factorials
    Regression modeling: Hypothesis testing in Simple and Multiple regressionmodels
    Introduction to Practical components of Industrial and Clinical Trials Problems:
    Statistical Analysis Using Excel, SPSS, MINITAB®, DESIGN OF EXPERIMENTS, R -
    Online Statistical Software’s to Industrial and Clinical trial approach

    Unit-V 7Hours
    Design and Analysis of experiments:
    Factorial Design: Definition, 22, 23design. Advantage of factorial design
    Response Surface methodology: Central composite design, Historical design,
    Optimization Techniques

    Recommended Books (Latest edition):

    1. Pharmaceutical statistics- Practical and clinical applications, Sanford Bolton,


    publisher Marcel Dekker Inc. NewYork.
    2. Fundamental of Statistics – Himalaya Publishing House- S.C.Guptha
    3. Design and Analysis of Experiments –PHI Learning Private Limited, R.
    Pannerselvam,
    4. Design and Analysis of Experiments – Wiley Students Edition,
    Douglas and C. Montgomery

    157

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