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ADDICTION DRUG USE HALLUCINOGENS

What to Know About Magic Mushroom Use
By Elizabeth Hartney, BSc, MSc, MA, PhD
Updated on July 20, 2022
Medically reviewed by Steven Gans, MD
Print
Side effects of magic mushrooms
Verywell / Alison Czinkota
Table of Contents
What Do Shrooms Do?
Potential Benefits
Common Side Effects
Signs of Use
Addiction & Withdrawal
How to Get Help
Frequently Asked Questions
Magic mushrooms are wild or cultivated mushrooms that contain psilocybin, a
naturally occurring psychoactive and hallucinogenic compound. Psilocybin is
considered one of the most well-known psychedelics according to the Substance Abuse
and Mental Health Services Administrations (SAMHSA).1
Psilocybin is classified as a Schedule I drug, meaning that it has a high potential

for misuse and has no currently accepted medical use in treatment in the United
States.
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Verywell Mind Podcast, featuring psychologist Brian Pilecki, shares the types of
conditions psychedelics might treat, and the best resources to learn more
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Although certain cultures have been known to use the hallucinogenic properties of
some mushrooms for centuries, psilocybin was first isolated in 1958 by Dr. Albert
Hofmann, who also discovered lysergic acid diethylamide (LSD).
Magic mushrooms are often prepared by drying and are eaten by being mixed into food
or drinks. Although, some people eat freshly picked psilocybe mushrooms.
Also Known As: Magic mushrooms are also known as shrooms, mushies, blue meanies,
golden tops, liberty caps, philosopher's stones, liberties, amani, and agaric.
Drug Class: Psilocybin is classified as a hallucinogen.
Common Side Effects: Magic mushrooms are known to cause nausea, yawning, feeling
relaxed or drowsy, introspective experience, nervousness, paranoia, panic,
hallucinations, and psychosis.
How to Recognize Shrooms

Psilocybe mushrooms look like dried ordinary mushrooms with long, slender stems
that are whitish-gray and dark brown caps that are light brown or white in the
center. Dried mushrooms are a rusty brown color with isolated areas of off-white.
Magic mushrooms can be eaten, mixed with food, or brewed like tea for drinking.
They can also be mixed with cannabis or tobacco and smoked. Liquid psilocybin is
also available, which is the naturally occurring psychedelic drug found in liberty
caps. The liquid is clear brown and comes in a small vial.
What Do Magic Mushrooms Do?

Magic mushrooms are hallucinogenic drugs, meaning they can cause you to see, hear,
and feel sensations that seem real but are not. The effects of magic mushrooms,
however, are highly variable and believed to be influenced by environmental
factors.2
Click Play to Learn More About Shrooms

This video has been medically reviewed by John C. Umhau, MD, MPH, CPE.
A number of factors influence the effects of magic mushrooms, including dosage,

age, weight, personality, emotional state, environment, and history of mental
illness.
While psilocybe mushrooms are often sought out for a peaceful high, shrooms have
been reported to induce anxiety, frightening hallucinations, paranoia, and
confusion in some.3 Hospital admissions related to the use of magic mushrooms are
often connected to what is known colloquially as a "bad trip."
What the Experts Say

Magic mushrooms have been used for thousands of years for both spiritual and
medicinal uses among indigenous people of America and Europe.
Shrooms have a long history of being associated with spiritual experiences and
self-discovery. Many believe that naturally occurring drugs like magic mushrooms,
marijuana, and mescaline are sacred herbs that enable people to attain superior
spiritual states. Others take magic mushrooms to experience a sense of euphoria,
connection, and a distorted sense of time.
The psilocybin found in shrooms is converted to psilocin in the body and is

believed to influence serotonin levels in the brain, leading to altered and unusual
perceptions. The effects take 20 to 40 minutes to begin and can last up to 6 hours—
the same amount of time it takes for psilocin to be metabolized and excreted.4
Potential Benefits of Magic Mushrooms
While some people take magic mushrooms solely for their peaceful high, they may
also provide a few benefits that are more medicinal in nature.
Medical Use
Can magic mushrooms help with medical conditions? Some say yes. In 2018,
researchers from Johns Hopkins University recommended reclassification of
psilocybin from Schedule I to Schedule IV in order to allow for medical use.
As a Schedule 1 drug, psilocybin cannot be prescribed for medicinal use. If its

classification is changed, psilocybin mushrooms could then potentially be available
by prescription.
Researchers at Johns Hopkins found that psilocybin was an effective treatment for
depression and nicotine and alcohol addictions, as well as other substance use
disorders.5 Studies have also shown that magic mushrooms were effective for
relieving the emotional distress of people with life-threatening cancer diagnoses.6
The Center for Psychedelic and Consciousness Research at Johns Hopkins is also
researching how psychedelics affect a variety of conditions such as:
Alzheimer's disease
Anorexia nervosa
Opioid addiction
Post-traumatic stress disorder (PTSD)
Post-treatment Lyme disease syndrome
Microdosing
One study found that people who self-medicated with small dosages of psilocybin
were able to relieve cluster headaches while avoiding any psychoactive effects of
the drug.7 This type of practice is often referred to as microdosing, or taking
very small amounts of a drug to test its benefits while minimizing unwanted side
effects.
It should be noted that researchers tend to advise against self-medicating with

psilocybin because, outside of a clinical setting, it may be harder to manage your
anxiety while under the influence (potentially leading to a bad trip), you may take
too high of a dosage, and it's hard to know the purity of the drug if you're
purchasing it from an unregulated source.8
In addition, people with pre-existing mental health conditions may be more likely
to experience adverse effects from psilocybin.
Comprehensive Study Finds Microdosing Boosts Mental Health
Psychedelic-Assisted Psychotherapy
Some psychedelic agents are currently being investigated for their benefits when
used in combination with psychotherapy. Psilocybin is one that is being considered
as a psychedelic therapeutic for both addiction and anxiety associated with
terminal illness.9
This therapy may work, in part, through its effects on personality. One small-scale
study involving subjects with treatment-resistant depression found that, after
engaging in psilocybin therapy, their neuroticism scores decreased while their
scores in extraversion, openness, and conscientiousness increased.10
Are Psilocybe Mushrooms Legal?

In 2019, Denver became the first city to decriminalize mushrooms. Oakland became
the second city less than a month later. Other U.S. cities have followed suit,
including Santa Cruz in California and Ann Arbor in Michigan.
This does not mean that shrooms are legal, but that the city is not permitted to
"spend resources to impose criminal penalties" on people in possession of the drug.
However, in 2020, Oregon became the first state to legalize psilocybin-assisted
therapy.
What Is Psilocybin Therapy?

Common Side Effects of Psilocybin Mushrooms
All hallucinogens carry the risk of triggering mental and emotional problems and
causing accidents while under the influence. Among adolescents, magic mushrooms are
frequently taken in combination with alcohol and other drugs, increasing the
psychological and physical risks.
The amount of psilocybin and psilocin contained in any given magic mushroom is
unknown, and mushrooms vary greatly in terms of the amount of psychoactive
contents. This means that it is very hard to tell the length, intensity, and type
of "trip" someone will experience.
Consuming shrooms can result in a mild trip, with feelings of relaxation or

drowsiness, to a frightening experience marked by hallucinations, delusions, and
panic. In the worst-case scenario, magic mushrooms have even been known to cause
convulsions.11
Side effects of magic mushrooms can include both physical and mental effects.
Physical effects of psilocybin mushrooms include:
Dilated pupils
Drowsiness
Headaches
Increased heart rate, blood pressure, and temperature
Lack of coordination
Muscle weakness
Nausea
Yawning
Mental effects of shrooms are:
Distorted sense of time, place, and reality

Euphoria
Hallucinations (visual or auditory)
Having introspective (spiritual) experiences
Nervousness
Panic reactions
Paranoia
Psychosis
More research is needed on the long-term, lasting side effects of magic mushrooms.
But it has been reported that people can experience long-term changes in
personality, as well as flashbacks, long after taking mushrooms.
Since magic mushrooms look similar to poisonous mushrooms, poisoning is yet another
potential risk of taking these drugs. Mushroom poisoning can cause severe illness,
organ damage, and even death.
It's also common for magic mushroom products to be contaminated. A study of 886
samples alleged to be psilocybin mushrooms were analyzed by Pharm Chem Street Drug
Laboratory. Only 252 (28%) were actually hallucinogenic, while 275 (31%) were
regular store-bought mushrooms laced with LSD or phencyclidine (PCP) and 328 (37%)
contained no drug at all.12
Help for Mushroom Poisoning

If you suspect that you or someone you care about has consumed a poisonous
mushroom, call poison control right away at 800-222-122. Don’t wait for symptoms to
occur. They are available 24 hours a day, seven days a week, 365 days a year.
Signs of Magic Mushroom Use

If your loved one is using shrooms, they may be nauseous or appear nervous or
paranoid. In the case of drug use, it's always important to pay attention to any
changes in sleep and eating patterns, as well as shifts in mood, personality, and
social activities.
There are rare but potential long-term side effects of hallucinogens, including
disorganized thinking, mood changes, paranoia, and/or visual disturbances.
Hallucinogen persisting perception disorder (HPPD) occurs when a person experiences

hallucinations or visual disturbances long after using a hallucinogenic drug. These
are also known as "flashbacks" and can be mistaken for a brain tumor or a stroke.13
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Verywell Mind

Mental Health A-Z

ADDICTION DRUG USE HALLUCINOGENS

Psilocybin is classified as a Schedule I drug, meaning that it has a high potential

Press Play for Advice on Psychedelic Use

Follow Now: Apple Podcasts / Spotify / Google Podcasts

How to Recognize Shrooms

What Do Magic Mushrooms Do?

Click Play to Learn More About Shrooms

A number of factors influence the effects of magic mushrooms, including dosage,

What the Experts Say

The psilocybin found in shrooms is converted to psilocin in the body and is

As a Schedule 1 drug, psilocybin cannot be prescribed for medicinal use. If its

It should be noted that researchers tend to advise against self-medicating with

Are Psilocybe Mushrooms Legal?

What Is Psilocybin Therapy?

Consuming shrooms can result in a mild trip, with feelings of relaxation or

Physical effects of psilocybin mushrooms include:

Distorted sense of time, place, and reality

Help for Mushroom Poisoning

Signs of Magic Mushroom Use

Hallucinogen persisting perception disorder (HPPD) occurs when a person experiences

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