Isoxsuprine Hydrochloride
Isoxsuprine Hydrochloride
Isoxsuprine Hydrochloride
Dosage Action
Frequency &
Route
Adjunctive Sympathomimetic - Central Nervous - It should not be Assessment & Drug
Generic Name: therapy in with beta- System: given Effects
Pharmacologica
treatment of l Class: adrenergic Dizziness, immediately
Isoxsuprine cerebral vascular stimulant activity trembling, after childbirth - Monitor for therapeutic
hydrochloride insufficiency, Peripheral and with slight nervousness and and labor. effectiveness: Response
premature labor Vasodilator effect on alpha weakness - Contraindicated to treatment of
Brand Name and peripheral receptors. - Heart: Low to patients peripheral vascular
vascular disease, Vasodilating blood pressure, allergic to this disorders may take
Duvadilan such as action on arteries palpitations, fast medicine. several weeks. Evaluate
Vasodilan arteriosclerosis within skeletal heart rate, - Contraindicated clinical manifestations
Tidilan obliterans, muscles is greater increase fetal to patients with of arterial insufficiency.
thromboangitis than on cutaneous heart rate if used presence of - Monitor BP and pulse
obliterans vessels. Also as IV infusion in arterial of the mother and fetal
(Buerger's causes cardiac premature labor, bleeding; heart rate of the baby
disease), and stimulation and lung swelling and parenteral use during infusion; may
Raynaud's disease. may produce flushing. in presence of cause hypotension and
bronchodilation, - Gastrointestinal hypotension, tachycardia. Supervise
Cerebral Vascular mild inhibition of : Nausea, tachycardia. ambulation.
Insufficiency, GI motility, and vomiting and - Safe use in - Observe both mother
Peripheral uterine relaxation. abdominal pregnancy and baby for
Vascular Disease distress. (category C) or hypotension and
Adult: PO 10–20 - Miscellaneous: lactation is not irregular and rapid
mg t.i.d. or q.i.d. Rash and allergic established. heartbeat if isoxsuprine
reactions such as is used to delay
IV/IM- To arrest hives, difficulty premature labor.
premature labour- breathing, Hypocalcemia,
The recommended tightness in the hypoglycemia, and ileus
dose is 200-500 chest. have been observed in
mcg/min via IV babies born of mothers
infusion until taking isoxsuprine.
control is
achieved, then 10 Patient & Family
mg 3-8 hourly via Education
IM injection for
several days. Notify physician of
adverse reactions
(skin rash,
palpitation,
flushing) promptly;
symptoms are
usually effectively
controlled by
dosage reduction or
discontinuation of
drug.
Prevent orthostatic
hypotension by
making position
changes slowly and
in stages,
particularly from
lying down to
sitting upright and
avoid standing still.
Note: For treatment
of menstrual
cramps, isoxsuprine
is usually started 1–
3 d before onset of
menstruation and
continued until pain
is relieved or
menstrual flow
stops.
Do not breast feed
while taking this
drug without
consulting
physician.