Manual MacroPATH

MILESTONE
H E L P I N G
P A T I E N T S
MacroPATH e MacroPATH Basic

QX Series
Digital Imaging System for the grossing room
Operator Manual - MM161-001

MacroPATH and MacroPATH Basic QX Series MM161-001 – Operator Manual
Thank you for choosing one of our systems and welcome to the ever more crowded club of Milestone
laboratory instrumentation users.
We feel confident that you will be fully satisfied adding this new device to your laboratory.
We recommend to ready carefully this operator manual and to always keep it within reach for convenient and
quick referencing.
For any clarification or request for assistance, please contact our representative in your country:
Or contact
Milestone s.r.l.
Via Fatebenefratelli, 1/5
24010 Sorisole (BG) Italy
Tel. +39.035.412 8264
Fax +39.035.575498
web site www.milestonemed.com
e-mail marketing@milestonemedsrl.com
Read carefully this manual before using the instrument.
MM161-001- MacroPATH and MacroPATH Basic QX Series - Operator Manual

2018-11
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INDEX
INDEX ................................................................................................................................................................ 4
1. INTRODUCTION ........................................................................................................................................ 6
1.1. Symbols used .................................................................................................................................... 6
1.2. Introduction to MacroPATH and MacroPATH Basic .......................................................................... 6
1.3. Technical Specifications .................................................................................................................... 7
1.4. Transport and storage conditions ...................................................................................................... 8
1.5. Warning information ........................................................................................................................... 9
1.6. Antivirus ............................................................................................................................................. 9
1.7. MacroPATH data backup (PICTURES OF FILES) .......................................................................... 10
1.8. Milestone remote connection ........................................................................................................... 10
1.9. MacroPATH and MacroPATH Basic labels ..................................................................................... 10
2. INSTALLATION ........................................................................................................................................ 11
2.1. Unpacking and checking MacroPATH and MacroPATH Basic components .................................. 11
2.2. Overview of PC Monitor (only for MacroPATH) ............................................................................... 13
2.3. Camera Overview ............................................................................................................................ 14
2.4. Table stand installation for MacroPATH PC Monitor ....................................................................... 15
2.4.1. PC Monitor connections ........................................................................................................... 16
2.5. Camera Lens Installation ................................................................................................................. 17
2.5.1. Camera Orientation ................................................................................................................. 18
2.5.2. Camera connections ................................................................................................................ 19
2.6. How to change the language of the Operating System and Keypad .............................................. 20
2.7. Software installation (only for MacroPATH BASIC) ......................................................................... 22
2.7.1 License activation ........................................................................................................................ 26
2.8. Foot pedal control configuration (only for MacroPATH Basic) ........................................................ 27
3. WORKING WITH MacroPATH ................................................................................................................. 28
3.1. Start MacroPATH ............................................................................................................................. 28
3.2. Log in and Log out ........................................................................................................................... 28
3.3. Overview of the functions ................................................................................................................ 29
3.3.1. Shortcut Keys........................................................................................................................... 30
3.3.2. Multifunctional buttons ............................................................................................................. 31
3.3.3. Foot pedal control .................................................................................................................... 32
3.4. How to operate ................................................................................................................................ 33
3.4.1. Create a file.............................................................................................................................. 33
3.4.2. Edit a file .................................................................................................................................. 33
3.4.3. Files area Functions ................................................................................................................ 34
3.4.4. LIVE area Function .................................................................................................................. 37
3.4.5. Create/retrieve a case ............................................................................................................. 38
3.4.6. Save Image/Video/Audio ......................................................................................................... 38
3.4.7. Thumbnails .............................................................................................................................. 39
3.4.8. Basic camera settings .............................................................................................................. 40
3.4.8.1 Advanced Camera Setting ....................................................................................................... 40
3.4.8.2 Optical Zoom Settings ............................................................................................................. 42
3.5. EDIT Functions ................................................................................................................................ 43
3.5.1. Tools ........................................................................................................................................ 44
3.5.2. Display utilities ......................................................................................................................... 48
3.5.3. Utility functions ......................................................................................................................... 49
3.6. SETTINGS ....................................................................................................................................... 50
3.6.1. General Settings ...................................................................................................................... 50
3.6.2. User Settings ........................................................................................................................... 51
3.6.3. Licensing settings .................................................................................................................... 52
3.6.4. Data storage settings ............................................................................................................... 53
3.6.5. Camera Settings ...................................................................................................................... 54
3.6.6. Calibration ................................................................................................................................ 55
3.6.7. Third-party settings .................................................................................................................. 56
3.6.8. Language, date and units of measure settings ........................................................................ 59
3.6.9. Appearance Settings ............................................................................................................... 60
3.6.10. Edit tools settings ..................................................................................................................... 62
3.6.11. Preferences settings ................................................................................................................ 64
4. MacroPATH as MULTISTATION VIEWER .............................................................................................. 65
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4.1. How to install MacroPATH as viewer .............................................................................................. 65

4.2. PC settings for MacroPATH Viewer ................................................................................................ 66
4.3. Integrating MacroPATH with LIS systems ....................................................................................... 67
5. MAINTENANCE ....................................................................................................................................... 71
5.1. MacroPATH cleaning up .................................................................................................................. 71
5.2. Safety precautions ........................................................................................................................... 71
5.2.1. PC Screen and Camera ........................................................................................................... 71
5.2.2. Keyboard and mouse ............................................................................................................... 72
5.2.3. Foot pedal control .................................................................................................................... 72
5.2.4. Touch-Pen ............................................................................................................................... 72
6. OPTIONAL PARTS .................................................................................................................................. 73
6.1. Table top camera holder .................................................................................................................. 73
6.2. Camera holder for hood type Grossing Station ............................................................................... 75
6.3. “C” bracket for MacroPATH camera ................................................................................................ 77
6.4. Floor Type Terminal Holder on wheels ............................................................................................ 78
6.5. Camera wall mount bracket ............................................................................................................. 79
6.6. Tube clamp camera mount .............................................................................................................. 81
6.7. Camera centring plate ..................................................................................................................... 83
6.8. Unit consisting of 3-jointed arm with VESA plate 75x75mm and 100x100mm ............................... 84
6.9. 3-jointed arm with wall-mounting ..................................................................................................... 85
6.10. Adapter Plate VESA 75/100mm ...................................................................................................... 85
6.11. Reinforcement plate for VESA arm ................................................................................................. 86
6.12. USB bar code readers ..................................................................................................................... 88
6.13. USB Waterproof (sealed) keyboard ................................................................................................. 89
6.14. Keyboard support with VESA connection ........................................................................................ 90
6.15. Macrostand ...................................................................................................................................... 91
6.16. Macro Stand Dry Area 230V and Macro Stand Dry Area 115V .................................................. 93
6.17. Foot Pedal Control ........................................................................................................................... 94
6.18. Sizing Ruler...................................................................................................................................... 94
6.19. Wire microphone .............................................................................................................................. 94
6.20. Licenses ........................................................................................................................................... 95
6.21. Mouse wireless laser in silicone ...................................................................................................... 96
6.22. POINT-OF-CARE CONTROL TERMINAL 19” ................................................................................ 97
6.23. Kit Camera MacroPATH .................................................................................................................. 98
6.24. Polarised lens for Camera ............................................................................................................... 99
7. TROUBLESHOOTING for MacroPATH ................................................................................................. 100
7.1. Milestone Remote connection ....................................................................................................... 100
7.1.1. How to install the Milestone Remote Connection software (for MacroPATH Basic) ............. 101
7.1.2. How to start the remote connection. ...................................................................................... 103
7.2. The camera is not working............................................................................................................. 103
7.3. The Live function is not working .................................................................................................... 104
7.4. The foot pedal control is not working ............................................................................................. 105
7.5. The Touch Pen is not working ....................................................................................................... 106
7.6. Touch-Pen and Touch Screen calibration ..................................................................................... 106
7.7. Return for repair to Manufacturer .................................................................................................. 113
7.8. PC Recovery Software .................................................................................................................. 113
8. DISPOSAL OF THE MacroPATH UNIT ................................................................................................. 122
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1. INTRODUCTION
1.1. Symbols used
The instructions marked with this symbol are important and must be read carefully.
An instruction accompanied by this WARNING symbol means you need to proceed

with caution. Failure to follow the instruction may endanger the user or cause damage
to the instrument.
Biohazard.
CE logo: this instrument complies with European Community directives.
IVD medical device according to directive 98/79/EC.
Symbol of the European WEEE directive (2002/96/EC):

electric/electronic material, do not dispose of in the environment.
Manufacturer.
Fragile
1.2. Introduction to MacroPATH and MacroPATH Basic
MacroPATH and MacroPATH Basic were designed to obtain images of histological samples and to ensure
their complete, safe and reliable handling.
MacroPATH and MacroPATH Basic differ by the fact that MacroPATH Basic does not include the PC Monitor
(see chapter 2.1).
The system has been designed for use in a laboratory and can therefore withstand the harshest laboratory
conditions (indoor use only).
MacroPATH's measurement function is strictly linked to the calibration performed by the

operator and is not controlled by the unit's software. That is why the measurements of
the sample obtained with MacroPATH CANNOT be taken into account for diagnostic
purposes. These values are purely indicative.
Indeed, a ruler must be placed near the sample (see image below) or a gauge must be used to obtain
a diagnostic value for the growth of the tumour, the extent of the lesion, etc.
The system must be calibrated in order to perform measurements with MacroPATH (refer to chapter 3.6.6
for the calibration procedure).
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1.3. Technical Specifications
Hardware (PC) (only for MacroPATH):

- CPU: Intel® Core™ i7 Processor 2.6 GHz
- RAM: 8GB DDR-4
- Hard disk: 500GB (SSD)
- Touch-pen: USB cable, tip of 1.5 mm diameter.
- Screen: 19" TFT LCD 1280X1024 16.7M Colour
IP 65 front panel
- Fanless
- Wi-Fi 802.11 A/B/G with Bluetooth v4.1 (*)
(*) subject to restrictions of use according to local radio frequency regulations to be checked before enabling
this function.
- available I/O (refer to chapter 2.2)
• 2x RS-232/422/485 Serial ports
• 2x Gigabit Ethernet LAN ports (RJ-45)
• 6x USB 2.0 ports
• 2x USB 3.0 ports
• 1x HDMI (max resolution 4096x2304@24Hz)
• 1x DP Display port (max resolution 4096x2304@60Hz)
• 2 X built-in 2W speakers
• Audio Mic-in 3.5mm jack input
• Line OUT 3.5mm jack
- Dimensions: LxHxD 470.5 x 415.2 x 75.6mm (18.52” x 16.34” x 2.97”)
- Weight: 7.4Kg (16.3lb)
- PC power supply: Input: 100-240V 47-63Hz 1.2-0.5A
Output: 18V DC 5.55A MAX
Software
- Operating System: Windows 10 Enterprise 64 bit
- MacroPATH SW: MacroPATH 5 including Milestone license
- image capture in JPEG format
- video capture in AVI format
- voice recording in MP3 format
- Microsoft Windows 10 and Microsoft Word are registered Microsoft Corporation Brands
- MacroPATH 5 software: Installed (with license) Possibility of managing up to five cameras (of the same
kind).
Minimum Hardware (PC) specifications (only for MacroPATH basic – PC Monitor not included):
- System: - Windows 7® Pro 32/64bit service pack1 or
- Windows 7® Ultimate 32/64bit service pack1 or
-recommended: Windows 10 Enterprise 64bit or Window 10 PRO 32/64bit
- CPU: Dual core processor 2.0 GHz
- RAM: 4 GB
- Hard disk: 250 GB
- USB: 4x2.0 ports
- LAN: 1 Gigabit LAN to connect the PC to the network
- Audio output (if requested)
- The USB ports are disabled when the PC is switched off.
- The hardware needs to be able to support the following software and drivers without any limitations to their
installation (the packages are supplied by Milestone)
- Additional libraries: - Microsoft .NET framework 4.0
- SQL Server Compact Edition 3.5
- Microsoft Visual C++ 2010 x86 Redistributable
- Windows Media Player 11 or 12
- Additional drivers: - Foot pedal driver
- Camera driver
- The software without libraries and/or drivers is not installed correctly and is to be considered incomplete.
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Camera:
- Camera resolution: max 20.1 Megapixel
- Video resolution: 1024 x 768 (HD) – 15-16 FPS, audio 352Kbps, 22kHz
- Audio rec.: 128 kbps
- Focus: Automatic
- White balance: Automatic
- Zoom: Optical 30x
- Fitted with a set of 3 lenses with different close up levels: +1 - +1.3 - +1.5
- Weight: 2.8Kg (6.1lb) (+250g camera power supply)
- Camera power supply:Input: 100-240V 50/60Hz 0.6A
Output: 24V DC 1.04A 25W MAX
- Included: Camera Support for photographic stand
- Built-in LED lighting
- Dimensions: 137 x 162 x 211mm (5.39” x 6.37” x 8.30”)
- USB data cable length: 4.5m (4.92yd)
Foot pedal control

- USB foot pedal control with 5 buttons
- IP X5
The manufacturer reserves the right to change and/or improve specifications without
notice and without incurring any obligation.
Environmental Conditions:
Operating temperature: 15°C – 30°C (59°F – 86°F)

Relative humidity: 10% - 80% non-condensing
1.4. Transport and storage conditions

Temperature: -20°C up to +60°C (-4°F +140°F)
Humidity: up to 80% (up to 50% at 40°C) non-condensing
Before turning MacroPATH on (when coming from a storage room), the unit must be
allowed to reach the environmental conditions (at least half an hour).
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1.5. Warning information
Use of the equipment in manners other than specified may void the warranty provided by the manufacturer.
PERSONAL DATA SAFETY

The Device described herein is not intended for managing personal data of natural persons. Personal data of
natural persons shall not be inserted into the Device during the use of the Device. The organization that uses
the Device shall implement appropriate measures to ensure that no personal data of natural persons are
inserted into the Device. All the data referred to a person and inserted into the device shall use, at least, the
“pseudonymization”, in such a manner that the personal data can no longer be attributed to a specific data
subject without the use of additional information, provided that such additional information is kept separately
and is subject to technical and organizational measures to ensure that the personal data are not attributed to
an identified or identifiable natural person.
DO NOT open the camera box. Opening it shall void the warranty.
The PC must only be connected to a 3-pole socket (it must have ground connection protections). This note
does not apply to the camera’s power supply.
Connect the system after installation and disconnect the system before cleaning up.
The equipment must be connected to sockets that are clearly visible to the operator.
The unit is not provided with spare fuses. If the system is not working properly, please contact your local
representative or the manufacturer (always provide the serial number of the unit, see label on the back of the
PC unit for MacroPATH whereas for MacroPATH Basic the label is on the back of the camera).
All of the system’s components must be supplied solely by the manufacturer.
In the event of malfunction, please shut down the PC and the camera’s power supply, then switch them on
again. If the system is still not working properly, please contact your local representative or the manufacturer.
In the event of a malfunction:

1) Switch off the PC. Unplug the PC from the main socket.
2) Turn the camera off. Unplug the power supply cable from the main socket.
3) Disconnect all optional parts (foot pedal control, keypad, bar code reader, camera, camera power
supply).
4) Clean and disinfect all parts of the unit as described in chapter 5.1
5) Place all parts of the equipment into the package supplied by the manufacturer (original package).
6) Send the unit to the manufacturer for repair.
It is very important to switch the MacroPATH camera and PC off before disconnecting the
camera’s USB connection, to avoid damaging the camera’s interface card.
1.6. Antivirus
Milestone recommends installing antivirus software. As Milestone does not install antivirus software, the user
can choose the preferred version according to their needs.
Pay attention when setting up the Antivirus so that the data flow on the USB/LAN protocols and accesses to
the Hard Disk are not restricted.
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1.7. MacroPATH data backup (PICTURES OF FILES)
Milestone strongly recommends storing all files and their pictures on a server with an
automated backup procedure.
Contact your local network/IT manager.
The image size with the suggested settings is 1.5MB/image (see chapter 3.4.8).
1.8. Milestone remote connection
MacroPATH comes with software to set up the connection to the Milestone customer support service when
technical support is required. To access it, refer to chapter 7.1.
1.9. MacroPATH and MacroPATH Basic labels
For the explanations of the symbols, refer to chapter 1.1.
Refer to the label attached to the device for device identification.
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2. INSTALLATION
2.1. Unpacking and checking MacroPATH and MacroPATH Basic components
This section illustrates the installation procedures and preliminary operations. Please read the following
chapters carefully before operating MacroPATH.
When unpacking check that all the parts are there.
MacroPATH (REF 370600) and MacroPATH Basic (REF 370605/SK) include the following parts (as
already specified, MacroPATH Basic does not include the “All in one PC”):
DESCRIPTION Q.ty IMAGE

POINT-OF-CARE CONTROL TERMINAL (“All 1+1
in one PC”) + Touch-Pen (there are two small
black keys on the touch-pen for the enter
command and right click of the mouse)
(not included with MacroPATH Basic)
Table stand for “All in one PC” 1

“All in one PC” power supply with Schuko cable 1

included
“All in one PC” power supply cable 1

115V~ (NEMA 5-15 C13)
Camera + Set of 3 lenses (lens +1,5 already 1

installed)
Camera power supply with cable included 1
11
115V~ Camera power supply cable NEMA 1-15 1

C8
Foot pedal control 1
Wire microphone 1
Sizing Ruler 1
Set of Allen screws 1
Included with both MacroPATH and 1

MacroPATH Basic:
Bootable 8GB USB key containing:
- Operator manual in electronic format
- Recovery software (see chapter 7.8)
Only included with MacroPATH: 1
32Gb USB key containing:
- MacroPATH pro-x 5 FULL software
- Operating system image software
Only included with MacroPATH Basic: 1
8GB USB key containing:
- MacroPATH pro-x 5 FULL software
In addition to the MacroPATH software in digital format, Milestone provides two USB keys
for every unit, containing the operating system and the relevant drivers. We strongly
recommend storing the USB keys in a safe place, as Milestone is not in a position to
supply other USB keys or copies thereof.
The pictures are only an example.
For the optional parts, see Chapter 6.
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2.2. Overview of PC Monitor (only for MacroPATH)
Description:
A) 2x RS-232/422/485 Serial ports
B) 2x Gigabit Ethernet LAN ports (RJ-45)
C) 6x USB 2.0 ports
D) 2x USB 3.0 ports
E) 1x HDMI (max resolution 4096x2304@24Hz)
F) 1x DP Display port (max resolution 4096x2304@60Hz)
G) 2 X built-in 2W speakers
H) Audio Mic-in 3.5mm jack input
I) Audio 3.5mm jack output
J) Power supply inlet
K) Reading lights
L) Equipotential terminal
Description:
1) On/Off
2) Enable/disable touch-screen
3) Volume
4) Brightness
5) Reading lights on/off
13
For PC installation, carefully remove the film from the touch-screen to prevent damaging it.
Before turning MacroPATH on (when coming from a storage room), the unit must be
allowed to reach the environmental conditions (at least half an hour).
It is advisable to turn the PC off completely at least once a week.
2.3. Camera Overview
A) Lens
B) LED light
C) Green power supply LED
A-B-C-D) Adjustments
E) Photographic fitting
F) LED lighting on/off
G) Power supply inlet
H) USB data cable
For the camera installation/clamping supports, refer to chapter 6.
14
2.4. Table stand installation for MacroPATH PC Monitor
Installing MacroPATH is easy and only takes a few minutes. Make sure that the power supply is not
connected during installation.
Table support installation as follows:
- Use the 4 screws provided to clamp the base to the column:
- Insert the PC Monitor into the column and secure it with the supplied screw:
15
The stand is already adjusted for the weight of the PC Monitor. If necessary, it is possible to adjust the
up/down (figure 1) and right/left (figure 2) force of the contrast springs.
Figure 1 Figure 2
2.4.1. PC Monitor connections
The power supply line needs a ground connection (Class I device)

Power supply line protection: 10A - C curve residual current circuit breaker, residual current: 30mA.
Connect the power supply cable to the PC Monitor panel and then to the power socket.
MICROPHONE POWER SUPPLY
FOOT PEDAL
TOUCH PEN CAMERA
Connect the USB foot pedal control to the USB port marked in brown.
Connect the microphone to the MIC-IN connector (pink 3.5mm jack)
Connect the other USB applications to the vacant ports (e.g. bar code, keypads, etc.)
Make sure that the audio microphone switch is ON before use.
Now that all of the connections are set up, install the cable cover panel (when the PC Monitor is installed on
the table support, it is not possible to insert the central screw).
Upon completing installation, MacroPATH can be turned on with the appropriate button.
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2.5. Camera Lens Installation
The camera kit comes with three different 82mm lenses +1 - +1.3 - +1.5 (close ups).
With these lenses it is possible to change the focusing distances.

To install a lens, simply screw it onto the threaded end of the camera shroud.
Lens +1.5 is mounted on the camera by default; upon installation it is possible to change it
if required, according to the information in the table below.
If the polarised lens is also provided as optional part (refer to chapter 6.24) first install the
polarised lens then also screw in the appropriate lens, ensuring it is the outermost one
GUIDE FOR ESTABLISHING THE DISTANCE OF THE CAMERA FROM THE SPECIMEN AND
WHAT TYPE OF LENS TO USE FOR OPTIMAL FOCUSING
Lens Allowed Distances Recommended

distance
Minimum Maximum
None 188cm (74”) infinite 200cm (78”)
+1 66cm (25”) 102 cm (40”) 95cm (37”)
+1.3 56cm (22”) 79cm (31”) 75cm (29”)
+1.5 50cm (19”) 69cm (27”) 65cm (25”)
The autofocus ability of the camera depends on environmental conditions. The values above are
experimental results obtained from Milestone tests captured at 100% of zoom level.
The supplied lenses (+1, +1.3, +1.5) cannot be combined using more than one at a time.
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2.5.1. Camera Orientation
On the back of the camera there are 2 levers to adjust the up/down tilt of the camera (see figure).
Loosen the levers until you find the best position and then tighten them up again.
On the back of the camera there are 2 knobs to adjust the right/left tilt of the camera (see figure).
Loosen the knobs until you find the right position and then tighten them up again.
To secure the camera you can use at least one pair of anchoring points (see figure).
The support can be rotated by 180° (take the knobs out, turn the support and put the knobs back in).
Alternatively, you can use the photographic fitting.
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2.5.2. Camera connections
Connect the power supply as pictured:
Connect the USB data cable to the relevant PC USB port.

The camera is one of the PC’s “USB devices”. Therefore, if you have a USB device (such
as a USB key) connected to the PC, and you wish to disconnect it, be careful not to
disconnect the camera from the PC. If it happens, follow the procedure described in
chapter 7.2.
Power supply line protection: 10A - C curve circuit breaker
Connect the cable to the power supply and to the mains.
When all of the connections are set up, the green LED turns on.
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2.6. How to change the language of the Operating System and Keypad
Not applicable for MacroPATH Basic.

The Operating System and keypad of the PC Monitor supplied by Milestone are in English. Follow the
instructions in this chapter ONLY IF you wish to change the language.
Follow these instructions to change the language of the Operating System:
- enter Windows Settings and click “Time & Language”.
- on the left-hand menu click “Region & Language”.
- click “Add a language”, choose the desired language from the displayed menu and click “Next” and “Install”
in the message after that. Spanish is chosen in the example below.
- when installation is complete, the chosen language will show under “Preferred languages”.
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- reboot the PC and the newly chosen language will be set in the operating system.
Follow these instructions to change the language on the Keypad. Spanish is chosen in this example.
- The status bar on the bottom left shows the default keypad language (ENG - English), click to enter these
settings.
- The following panel is displayed, choose the language for the keypad. Spanish is chosen for the keypad in
the example below.
21
2.7. Software installation (only for MacroPATH BASIC)
Installing the software without libraries and/or drivers DOES NOT result in appropriate
installation and is considered incomplete.
For correct MacroPATH operation, the user must have full access in read/write/edit mode for the following
folders:
To see the path C:\ProgramData\Milestone srl\MacroPath5\APPDATA you need to enable hidden folders
The software is provided in electronic format. Select the MacroPATH 5 PRO folder.
As administrator, run the internal file Setup.bat (right click and select Run as administrator).
Click Install when the window shown here on the right

opens up.
The camera drivers will be installed.
The installation request message might show several
times, always confirm it.
Click Accept when the window shown here on the

right opens up.
Microsoft .NET Framework 4 will be installed (if not

installed already).
22
Click Next when the window shown here on the right

opens up.
Select the installation folder and click Next.
Click Next when the window shown here on the right

opens up.
The software is now installed, click Close.
Foot pedal driver installation will start, click Next.
23
The drivers are installed, click Finish.
During the installation procedure, if the SQL Server Compact Edition 3.5 library was not already installed on
the PC, the following message could appear:
In this case it is required to proceed with the installation manually as follows:
Select “Packages” and “SQL Server Compact Edition”

and run the file.
When installation is completed, an icon appears on the desktop.
Right-click on MacroPATH 5 PRO icon and select “Properties”:
24
Select “Compatibility” and “Run this program as an administrator”.

Finally click “Apply” and OK.
It is now possible to launch the MacroPATH PRO software with a free 90-day license.
Follow the instructions provided in chapter 2.7.1 to get an unlimited license.
The first time the program is launched, the message shown below might be displayed:
Click OK to go ahead with camera driver installation.
25
2.7.1 License activation
Launch the MacroPATH software following the instructions provided in chapter 3.1. Then click
“Settings – Licensing” and enter the data required to activate the license, as explained below.
• Enter the Product key printed on the key containing the MacroPATH software (in the space marked by the
arrow in the figure above).
• Then click “Regenerate” (circled in the figure above).
• Click “Copy to Clipboard” to copy the machine’s ID (circled in the figure above).
• Paste into a text file or directly in the body of an e-mail.
• Describe the reason why a new license is required.
• Send an e-mail to customer support customersupport@milestonemedsrl.com also providing the serial
number of the camera and the software version.
• When you get the reply, save the file you receive from customer support.
• Click “Import file” (circled in the figure below) and select the saved “license.req5” file.
• Click “Save” at the bottom right of the Settings page (marked by the arrow in the figure below).
• Restart the MacroPATH software (it is not necessary to completely reboot the PC) and check that the
license status on the Settings page is “Unlimited” as shown below.
26
2.8. Foot pedal control configuration (only for MacroPATH Basic)
After connecting the foot pedal control to a USB port on the PC, follow these instructions:
go to “Settings” by clicking the appropriate icon, then select “Camera” (refer to chapter 3.6.5). Select the
serial number under “Foot pedal” - each foot pedal control has its own serial number:
The serial number of the foot pedal control starts with the letters ST and is printed on a
little sticker on the pedal.
DO NOT enter any serial number on the Keypad. Click “Clear” if this field is not empty.
If two or more serial numbers are displayed, check whether any external instrument is connected to the PC
using the same drivers. However, the serial number is found on the foot pedal control. Select the appropriate
serial number, save and restart the software. If the foot pedal control is still not working, follow the
instructions in chapter 7.4.
27
3. WORKING WITH MacroPATH

It is very easy to work with MacroPATH. All functions are described in the following chapters.
3.1. Start MacroPATH
Do not disconnect the camera if the PC is on
Let Windows start up and double click on the MacroPATH Pro icon on the desktop.
You can use your fingers or the provided touch pen for greater screen selection precision.
Milestone does not guarantee operation with any touch-pen other than the one provided
with the unit.
3.2. Log in and Log out
As a default setting, when the MacroPATH software is

launched, the user is logged in as Administrator.
To disable this function, the “auto log-in” field must be
unchecked (see chapter 3.6.2).
You need to be logged in as Administrator to use the main
functions. “Service” log-in is available for authorised personnel
only.
28
3.3. Overview of the functions
MacroPATH functions are grouped in 4 areas: FILES, LIVE, EDIT and SETTINGS.
AREA FUNCTION
FILES To browse, delete, add notes and present the existing files
LIVE To capture images, videos and audio files
EDIT To edit the captured images
SETTINGS To modify settings of the FILES, LIVE and EDIT areas
The following screen is available only for complete MacroPATH software (but not for the Viewer user).
E C
A B
D
G
F
L M
A STATUS ICON This displays the software status

B LOG IN This displays the current user and allows the user to log out by clicking it.
C EXIT To exit the MacroPATH application and go back to the PC operating system.
D FILE NAME Shows the name of the current file.
E LIVE To go back to the live display of the sample of the camera disabled by
default, value set at 0 seconds).
F IMAGE, VIDEO, To filter the thumbnails.
AUDIO FILTERS
G CAMERA BUTTON To turn the camera on/off and open the camera settings window (by holding
the icon down).
H MAIN SCREEN Sample observation area.
I ZOOM and Click on the button or directly on the touch-screen, to zoom in/out as required
STATUS BAR (from 0% to
100% in 7 steps). This function is also possible with the foot pedal control.
L FILE # File name/number entry area, as needed: either with the bar code or keypad.
M ENTER Required if the file number is entered manually.
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3.3.1. Shortcut Keys
Some functions can also be performed using certain buttons on the keypad (see table below):
Shortcut
Availability Hold down Function
Key
1: Files
2: Live
3: Edit
Always available
4: Settings
5: Exit
6: Logout
Q: Show file
W: Reset search
CTRL left +
FILES E: Print file
ALT left +
R: Present file
T: Add notes
A: Capture
S: Record Video
D: Record Audio
LIVE
F: Autofocus
G: Zoom +
H: Zoom –
Q: Select
W: Line size
E: Area size
R: Free sizing
T: Line
Y: Circle
U: Square
I: Arrow
O: Compass
P: Freehand
A: Text
S: Section (1)
Ctrl Left + Alt Left + Shift D: Section (A)
EDIT
Left + F: Section (A-1)
G: Section (1-A)
H: Quadrant
J: Multisection
K: Zoom region
L: Zoom IN
Z: Zoom OUT
X: Zoom FIT
C: Undo
V: Redo
B: Print
N: Record Audio
M: Save
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3.3.2. Multifunctional buttons
There are multifunctional buttons marked with a red triangle on the bottom-right corner of the icon.
To choose the main function, just press the icon.

To view multiple functions, press and hold for at least 3 seconds. A secondary menu will appear, then select
the various options.
Multifunctional buttons:
Camera management
Measuring tool
Line tool
Text tool
Section tool
Quadrant
Import cassette
Zoom tool (crop area and create a new image)
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3.3.3. Foot pedal control
Foot pedal controls:
5
4
2
1 3
1 Zoom in control
2 Zoom out control
3 Save: to capture images and save the edited images
4 Change work area: to switch between work areas (Start, Live, Edit)
5 Audio rec: to record an audio file in Live or Edit mode
32
3.4. How to operate

3.4.1. Create a file
Enter the file name/number in the “Case #” field, using the keyboard or bar code reader. Up to 40 characters
can be entered. Special characters such as “-” or “_” can be used as separators.
Go to LIVE by selecting the Live icon on the top right of the screen.
Acquire images, videos and audios using the icons on the left side or using the foot pedal control. (See
chapter 3.4.6)
3.4.2. Edit a file
Double click a thumbnail or select the EDIT icon on the top right of the screen to enter the EDIT
mode.
Edit the images using the tools in this area (see chapter 3.5).
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3.4.3. Files area Functions
In the FILES area it is possible to:
1. Browse/search or hide existing files with the relevant icon

2. Find files using the search function
3. Delete
4. Present
5. Printing
6. Add notes to the files.
A file can be retrieved by entering the name, date of creation/last change, the creator or author of the last
change or note, then click “Search”.
Reset search: press this icon to delete all previous changes and see the full list of files
34
Print case: press this icon for a complete or partial printout of the case. Select the template and
then the pictures to print.
Present case: press this icon to see the entire case (images, audio and video).
Add tag: press this icon to add a note to the case.
35
It is also possible to tag a case from LIVE. When a case is open and you are on the live screen, you can add
a tag to the case by pressing the “Add tag” icon as shown in the picture below.
Delete case: press this icon to delete a case. Double confirmation is requested to prevent errors.
Yes Yes
36
3.4.4. LIVE area Function
In LIVE it is possible to create/retrieve a case, acquire images, take a video or audio and edit supplementary
camera settings.
When the camera has been on for a long time, the buffer might automatically reset, during this procedure the
camera switches off and back on automatically as explained below.
Currently, the “camera wake up” procedure is: the live screen is stopped and the following message is
displayed. The maximum time is 90 seconds, during this period do not press any button, just wait.
This procedure may happen during the live stage or during editing.
Wait for the end of buffering, after which time you can use the camera again.
To extend the life of the camera, it goes into standby by default after one hour (see “Settings” menu, chapter
3.6.11). When MacroPATH remains idle for 1 hour, the camera therefore switches off and the live screen
turns black. If you want to switch on the camera, press its icon, as shown below.
When the camera is on “Buffering” may appear for a few seconds.
If you want to disable the camera standby, please contact our service department at
customersupport@milestonemedsrl.com.
37
3.4.5. Create/retrieve a case

Enter the case’s identifier by barcode reader or manually from the keypad to create or retrieve a patient
case.
With manual entry, press .
The picture can be taken with different zooms, in 7 pre-set steps. According to the Standard Zoom or
Extended Zoom setting it is possible to have two different zoom levels (hence two different frames of the
photographed areas).
To set Standard Zoom or Extended Zoom refer to chapter 3.6.5.
3.4.6. Save Image/Video/Audio
To save the image of the sample, use the zoom with the pedal control to view the desired area,
then press the capture icon or the Save button on the foot pedal control.
If the image is not captured (“Image not taken”) by pressing “Save”, please try again.
To import an image from a TWAIN peripheral (for example a microscope): press the “TWAIN”
icon and select the desired TWAIN source.
Use the TWAIN peripheral to capture the image (the software used is linked with the peripheral).
38
To enable TWAIN function, refer to chapter 3.6.7.
Make sure that the microphone switch is ON before using it. See the image below.
The microphone image provided is only an example.
Record a video by pressing the Rec Video icon. Press again to stop recording.
Before taking a video for the first time, you are asked to choose the most adequate compression.
Milestone suggests to use “Microsoft video 1” compression.
Go to SETTINGS to change compression (see chapter 3.6.11)
Press the Rec Audio button to make a recording. Press again to stop recording.
3.4.7. Thumbnails
Saved images, videos and audios appear on the right of the screen (thumbnails).
39
3.4.8. Basic camera settings

Press and hold the camera icon for at least 3 seconds to open the camera settings window. In this window it
is possible to set:
3.4.8.1 Advanced Camera Setting
• SNAPSHOT QUALITY: to change the snapshot quality.

• OPERATING MODE: shooting method setting
✓ Automatic Shooting Mode: the camera chooses the basic settings automatically
✓ Semi-Automatic Shooting Mode: semi-manual entry of camera parameters
F Number: focal ratio setting, we recommend setting an average value to achieve an optimal
light/field depth ratio (F 6.3 is recommended).
ISO: image grain setting, we recommend setting a low value to achieve greater image detail
(ISO80).
Exposure Compensation: manually changing the brightness of the image, set at a value
other than 0 if you want a darker or lighter image (0 is recommended).
White balance: white balance setting (light source selection)
During installation it is NOT necessary to perform white balance setting for the camera. The
digital camera will auto-balance the white according to the light conditions where the
MacroPATH is positioned.
The user may select “AUTO” where the camera automatically adjusts the white balance or it
is possible to select the type of laboratory light source from the options in the list shown
below, so as to obtain the most realistic colour.
40
“Auto” is selected by default and it is indicated when you are not certain of the type of light
source of the cutting station.
These changes are applied after pressing “Save and Close” and it is not necessary to reboot
the software.
If there are additional cameras, modify the settings for each cam separately.
The changes are saved in the configuration in use (see chapter 3.6.1).
• HDR Shooting Mode: if necessary, the camera takes various shots and overlaps them
• Firmware Version: this is the camera’s Firmware version
This chapter explains how to set the capture quality (5-10-20 Mpx) but the image size also depends on the
compression quality (to set the compression quality see chapter 3.6.4).
Milestone suggests setting a snapshot quality of “10Mpx” and “Standard” compression.
This is a good compromise between file size (disk space) and image quality.
For images used for publications (articles, documents, etc.) Milestone suggests setting a capture quality of
“20Mpx” and “Full” compression.
The table below indicates the image file size in the various configurations:
Compression quality
Standard Full Low
(medium) (high) (low)
Snapshot quality
20 Mpx 2.3MB 12.7MB 1.8MB
10 Mpx 1.5MB 7.4MB 970kB
5 Mpx 750kB 4MB 520kB
Note that the space required for saving each image is twice that shown in the table above. In fact, the
system automatically saves each image in both JPEG and m5p formats.
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3.4.8.2 Optical Zoom Settings
This screen shows the zoom levels for Standard or Extended setting.
To set Standard or Extended Zoom refer to chapter 3.6.5.
The figure below shows the default settings.
If there is the Table top camera holder (CODE 370455) with MACROSTAND WA cutting board (REF
370285) we recommend using the default settings with standard zoom as in the figure above.
With Table top camera holder (CODE 370455) with MACROSTAND XL cutting board (REF 370606) we
recommend using the values shown in the table below with standard zoom:
It is nevertheless possible to change the single zoom steps manually by clicking on the individual boxes and
entering the required value.
It is only possible to enter whole numbers.
42
3.5. EDIT Functions
Click once on the image or click on the Edit button to enable annotation mode.
In annotation mode it is possible to add text, measurements, graphic elements and sections to the image,
examine the sample, record audio or print out directly.
Select: click the Select button to use the mouse like a pointer, or to select each element for
editing. Once it is selected it is possible to move the element and edit: line, colour, background
colour, text colour and text size with the multifunction keypad.
Section Name
Section Number
Line colour and text

Background colour
Line thickness
Text size
Note rotation
Enable/Disable labels
43
3.5.1. Tools
Sizing
Click and hold down the Sizing icon with the mouse or touch pen.
The tool bar circled in red will appear.
Click the “Measure length” icon to draw lines; the system calculates the length of the line.
Click the “Sizing - Area” icon to draw an area on the sample; the system calculates the drawn area.
Click the “Sizing - Free” icon to draw freehand lines; the system calculates the length of the line.
The Software needs to be calibrated when the unit is installed and every time the camera height
changes. See chapter 3.6.6 for the calibration procedures. MacroPATH's measurement
function is strictly linked to the calibration performed by the operator and is not controlled
by the unit's software. That is why the measurements of the sample obtained with
MacroPATH CANNOT be taken into account for diagnostic purposes. These values are
purely indicative.
Indeed, a ruler must be placed near the sample (see image below) or a gauge must be used to obtain
a diagnostic value for the growth of the tumour, the extent of the lesion, etc.
If there is no calibration, the <?> symbol appears on the image.
44
Draw Lines
Click on the Line icon with the mouse or with the touch-pen. Point and drag the required line on
the photo. Hold down the button to activate the multiple choice of rectangles, circles, arrows,
compass and freehand line.
Add Text
Text can be added by clicking the Text icon; click and drag on the image area where you wish to
place the text and enter the text from the keypad or bar code reader.
PRE-ENTERED TEXT: (Also see chapter 3.6.8 for the text entry modes)
When the list is customised, click the Text icon and hold it down until the list is displayed: click the text you
wish to enter and then on the area of the image where you wish to position it.
Add Sections
Click on the Sections icon with the mouse or with the touch-pen. Position and drag the required
line on the photo.
Hold down the button, thereby enabling the multiple choice of the various styles (A, 1, A-1 or 1-
A).
Change the sequence of letters and numbers by clicking with the pointer on the section line and then with
the multifunction keypad. Use the controls (see the arrow in the image below) to adjust the sequence of
letters and numbers (see description of multifunction keypad in this chapter).
45
Add Quadrants
Hold down the Quadrants button to view the available tools (4 or 6 quadrants). Choose a point
on the screen to trace the required quadrants on the image.
The quadrant label consists of three letters: the first can be L (Left) or R (Right), the second is the
progressive letter indicating the quadrant and the third can be A (Anterior), M (Median) or P (Posterior).
By clicking on the section line with the Select button (Select, see chapter3.5), it is possible to rotate the
quadrants and change the text and line style.
Add cassette pattern
Click on and hold down the Cassette icon thereby activating the multiple choice of cassette
styles (normal or supermega). Choose a point on the screen and drag the required sections on
the photo.
Rotate the cassettes using the multifunction keypad in the bottom left corner of the work area. See Edit
functions (3.5) “Selection” tool.
46
Zoom region
Click on the ZOOM icon with the mouse or with the touch-pen. Position and drag the required line
on the photo: the software automatically creates a new cropped image.
Hold down the button, thereby enabling the multiple choice (zoom in, zoom out and restore)
Grid
Click on the Grid icon with the mouse or with the touch-pen to add a grid.
In SETTINGS, it is possible to edit the colour, thickness and spacing of lines. The camera
must be calibrated before using the Grid tool. See section 3.6.6.
47
3.5.2. Display utilities
Image, audio and video Library
The user can easily view case assets in the library by using the following controls.
1. Scroll arrows (up/down) at the top and bottom of the library let you move through the case.
2. Images/Audio/Video tabs at the top of the library let you filter individual file types. (Example:
unchecking the Images tab only displays the captured videos and audio files).
Play Video
Select a video thumbnail on the right of the screen and click on it. The video will automatically start once
selected. The Viewer screen appears and the video starts. At the end, the window must be closed to go back
to the main screen.
Play Audio
Click an audio thumbnail in the library: it plays automatically once selected. No windows appear.
48
3.5.3. Utility functions
Undo and Redo

To remove the last change made to the image: press Undo and the last change will
disappear (it deletes from first to last change). Press Redo to restore a removed
change.
Undo/Redo: these functions do not work with saved and retrieved images.
Delete
The Delete function deletes one or more case assets in multiple ways. A deleted image
cannot be restored at a later time.
1. Choose a thumbnail of the image, audio or video from the library and press the
Delete icon.
2. Select and hold down the Delete icon to open the window several files can be
deleted at the same time. A message will ask you to confirm deletion.
Audio Recording
Select the image you wish to add an audio comment to. Press the Rec Audio button to start the
recording, and press it again to stop it. The saved audio icon appears on the right of the screen
under the related image.
Save image
When all of the necessary changes have been made, click or press directly on the Save icon
on the screen to save them. Images can also be saved directly with the foot pedal control by
pressing the Save command.
In any case, when you exit an image without saving the changes, the system asks you if you
wish to save them.
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3.6. SETTINGS
Only authorised users can access and modify settings (see chapter 3.6.2).
Press SAVE and restart to apply the changes.
Click on the Settings button: the MacroPATH Settings screen opens.
3.6.1. General Settings
Click on General and follow the instructions on how to do a backup of application settings, user settings or a
full backup. We recommend exporting the backup file to another PC or a server.
50
3.6.2. User Settings
Click Users to create, modify or eliminate a user and/or change user rights.
Switch enabling on or off (possibility of performing a given action) by checking or unchecking the related
control checkbox.
When all of the settings have been entered, press Save User and Save.
Users’ rights table:
Can create new cases Possibility of creating a new case

Can delete cases Possibility of deleting the entire case
Can browse cases Possibility of working with the browse cases icon.
Can add elements Possibility of acquiring new images, audio or video
Can edit elements Possibility of working in Edit mode
Can delete elements Possibility to delete images
Autologin Possibility to skip the login screen and access the program directly.
By ticking this option, if another user was set for auto-login, he/she would
be disabled to enable the current user.
Can edit General Possibility to operate in the Settings-General screen; for example, the full
backup function can be used. Refer to chapter 3.6.1.
Can edit Users Possibility of working in the Settings/user screen
Can edit app settings Possibility to modify settings in the blue fields: storage folders, licensing,
camera preferences (calibration) and connections with external programs
(see following chapters).
Can calibrate Possibility to calibrate images
Can edit user settings Possibility to edit settings in the green fields, regarding languages, display
options and general user settings (see following chapters).
It is possible to set default settings available under green tabs, as “Localization”, “Appearance”, “Tool” and
“Preferences”, for all existing users by clicking “Set for all existing users” in the “General” chapter 3.6.1.
51
3.6.3. Licensing settings
Do not perform the procedure without assistance from MILESTONE customer support. DO
NOT MODIFY THE DATA.
Click the Licensing button to manage the licensing file or to check the licensing status.
To obtain a new licence (if required):

• Enter the PRODUCT KEY code printed on the supplied USB key (see the arrow in the previous picture),
• Press “Regenerate” (marked by the circle in the figure above),
• Press the “Copy to Clipboard” button, to copy the Machine ID code (circled in the figure above),
• Paste onto a text file or directly in an email message
• Describe the reason why a new license is required
• Send the information by email to customersupport@milestonemedsrl.com,
• When you receive the reply mail, save the file you received from the Milestone customer support
service,
• Press “Import file” (circled below) and select the saved lic5 file,
• Press “Save” (indicated by the arrow below).
• Restart MacroPATH and make sure that the license level is “Unlimited” or “Editing” according to the
license that you have bought, as shown below:
The MacroPATH unit is provided with a full license file already installed.
52
3.6.4. Data storage settings
Click on the Storage button to either change or add new storage folders (up to 3). The system automatically
saves files in each folder selected.
For appropriate installation, specifically with multiple stations (when several MacroPATH units are installed or
installed in the office PCs with the “Editing” license), it is advisable to have the unit save data on a shared
folder (a server, for example). For correct system configuration, the first path needs to be the shared folder
located on the server. This folder must be set up for full control for each account (read/write/edit) and for
each PC running the MacroPATH software.
Accordingly, the second path should be a local folder (located on the PC’s internal hard disk).
For Windows 7 and Windows 10, a default folder (the user can obviously change it):
C:\Users\Public\Documents\Milestone srl\MacroPath5\IMAGES
As shown in the picture below (which illustrates the example of the first path):
\\SERVER\Pathological Anatomy\Laboratory\MacroPath\IMAGES
The local folder will ONLY store the files created and opened by the MacroPATH you are using. The shared
folder on the server will collect ALL the files created and managed by all the workstations/units.
Milestone strongly recommends storing the files on a server with an automated backup
procedure. Contact your local Network/IT Manager.
Data compression: you can define three different image compression levels: Full Quality, Standard and
Low file size.
See chapter 3.4.8 to select the best degree of compression depending on image quality.
53
High definition this function is not necessary for the camera (it is developed for previous camera models).
Enabled shared folder management

Shared folder management is useful when several MacroPATH stations are working on the same files. In
fact, with this function enabled, when a case is opened by a station and another MacroPATH station tries to
open it, an error message is displayed, informing that the case is already opened by another System and
displaying its IP address and when the case has been opened. An example is shown below.
Before using this function, please contact your Technical Department and
3.6.5. Camera Settings
Click the “Camera” button to enter the camera settings page
Select the required camera (“Cam1” or “Cam2”, “Cam3”, “Cam4” and “Cam5”
depending on how many there are).
Click on Camera short name to edit the camera name.
Select:
• Trust external calibration: MacroPATH to use the calibration factors of previous files and not those
of the software.
• Force calibration: MacroPATH will require calibration to be carried out on every new image (helpful
when changing capture camera height).
• Auto measure: function not available.
• Vertical Flip Image: the image is flipped along the vertical axis.
• Horizontal Flip: the image is flipped along the horizontal axis.
• Priority: If two or more cameras are connected to MacroPATH, you must choose the selection
sequence.
It is essential to set the priority when working with multiple cameras. ‘Live’ shows the
buttons for the various connected cameras, following the set order of priority.
54
• Zoom mode
Select one of the two suggested modes:
- Extended mode: 30x optical zoom default setting
- Standard mode: optical zoom optimised and customised for default use (for optimal and fast
focusing)
Standard Mode is selected by default.
Refer to chapter 3.4.8.2 illustrating the various levels for the two configurations.
When you change zoom mode the system must be re-calibrated following the procedure set out
in the chapter below.
• Foot Pedal Control: enable the foot pedal (if connected) by choosing the serial number from the list.
• Keypad: not enabled.
• Calibration Procedure: by pressing this button it is possible to calibrate the unit, as explained in the
following chapter.
3.6.6. Calibration
Click the “Calibration Procedure” button and position the ruler on the work surface.
We recommend placing the ruler starting from the “0 mm” measurement on the left-hand side; also, the ruler
should be placed HORIZONTALLY at the CENTRE of the live image.
Press Focus at the top right if the image is not focused, then press Go to take the first picture required for
calibration.
Insert the distance (in mm) between the two edges of the image (see picture). Then press NEXT.
Repeat the action 7 times (i.e. for the 7 zoom levels)

At the end press “Save”. The calibration procedure is now complete.
The calibration procedure is required every time the camera position or lens type are
changed.
Every camera has its own calibration; therefore, each camera needs to be calibrated
separately from any other that may be connected.
55
3.6.7. Third-party settings
It is possible to create shortcut buttons to launch external software (up to 3 different external applications,
not included):
Select the “External application” checkbox, as shown below. The image shows launching the “Notepad”
application as an example. To do this, fill the fields under “External application1”:
- “Application”: this is the address, in this case “C:\Windows\System32\notepad.exe”
- “Process”: this is the name of the application, in this case “Notepad”
- “Image”: it is the icon that will be displayed when the application is opened, it is required to select a “png”
image
- Label: in this case “Notepad” (which appears on the icon created).
Shutdown MacroPATH after launch: if selected, when the external application opens, MacroPATH closes.
Disable MacroPATH after launch: if selected, when the external application opens, MacroPATH is
disabled.
When the “Disable MacroPATH after launch” box is selected, a specific program (not
included, to be set by the user) must be installed to let the user go back to MacroPATH.
Otherwise, going back to MacroPATH is not possible and the user will need to restart the
MacroPATH application by means of Windows’ red “CLOSE” cross.
DO NOT select when in doubt
When all the fields described above have been filled in press “Save”. The icon referring to the application is
displayed under “Files”. In the example below, a “Notepad” icon appears.
56
If you press the button, Notepad opens automatically.
It is also possible to customise the “Exit” button in the “Customize exit button for already running processes”
section.
Under “Process” add the name of the program to be highlighted, import the .png image to “Image” that will
replace the button image, Exit and under “Label” enter the desired name for the new button.
When the "Exit" button is pressed, the program will be highlighted (only in cases where it has been
minimised on the status bar).
If the following checkbox is enabled:
when the exit button at the top of the screen is pressed, MacroPATH is minimised but not closed.
However, if the button is held down for at least 3 seconds, MacroPATH is closed.
You can enable this checkbox when MacroPATH is opened directly by its button (not by an external program
or an application) or also when MacroPATH is started from the command line.
However, you cannot enable this checkbox when working as a Twain device. In this case if you wish to
minimise MacroPATH upon exit, you are prompted to select the “Volatile” mode in “Settings→Third party” in
the Twain section.
57
Indeed, you can use the MacroPATH software and the camera as a TWAIN device which can be used by
external software (not included). Press Reinstall virtual driver and select:
Mode Description
The data of the case are not saved, only the images of the open case are
Volatile Shutdown temporarily saved in a "Twain" folder. Furthermore, MacroPATH will be closed
after importing the images.
The data of the case are not saved, only the images of the open case are
Minimize
Volatile temporarily saved in a "Twain" folder. Furthermore, MacroPATH is kept active
to icon
(minimised) after importing images.
The case data will be saved. Furthermore, MacroPATH will be closed after
Permanent Shutdown
importing the images.
Minimize The case data will be saved. Furthermore, MacroPATH is kept active
Permanent (Minimise (minimised) after importing images.
to icon)
In “Volatile” mode the case data are not saved, only the images of the open case are temporarily saved in a
Twain folder created in the same folder where the MacroPATH cases are saved (Settings-Storage). If you
wish to permanently save the images, enable the “Secondary Twain storage” checkbox in Settings –
Storage” and use the “Browse” button to select the path where to save them. The files are not saved at this
address, only the images with the saving date and time will be.
The following are some specifications regarding the TWAIN connection:

1. The MacroView DM TWAIN connection does not support Citrix technology of the desktop display nor
any other virtual machine. It was not developed or tested for these environments.
2. The window of the MacroView DM application always opens maximised. It can be re-sized, but it does
not retain the change between two successive Twain sessions.
3. If the operator closes the MacroView DM window during the Twain session by pressing “X” on the status
bar, the window closes immediately and the open Twain session is no longer managed. All the images
that must be transferred might be lost.
Also, in “Settings - Third party” select Enable Twain acquisition to import images from an external imaging
device (such as a microscope, not included). The device must be Twain to be able to send the images to
MacroPATH.
If enabled, a new “From Twain” button appears on the Live screen.
A MacroPATH case must be open to use the “Acquisition from Twain” button. An image will be imported in
the case. Measurements by using the calibration of the MacroPATH camera will not be possible on this
image.
To activate any setting performed in the "Settings-Third party" page, press Save in the lower right-hand
corner of the Settings page.
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3.6.8. Language, date and units of measure settings
From this screen it is possible to modify language (English is the default language), import new languages,
set system units of measure (millimetres, centimetres and inches), time and date format.
Select the desired Language from the drop-down menu, then press “Set Default” and reboot the system to
enable the modification.
Pre-set custom text lets you enter up to 100 different pre-set texts: press ADD (1 in the image below) and
type the category name (example text 1), then press the second ADD icon (2 in the image below) icon and
type the text (example text: text1)
This newly added text can now be used in EDIT MODE.
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3.6.9. Appearance Settings

Open the appearance screen as shown below.
Select the required theme from the list below.
Tick the Fullscreen checkbox to disable the pre-set list of names and enter the name of your laboratory.
Select the Virtual Keyboard checkbox to enable the keyboard icon. Click the icon to open the virtual
keyboard.
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Tick Easy interface to reduce the number of displayed icons
Easy interface Normal interface
Select Fine Tune Mode to edit icons, characters and sizes.
The Watermark (caption) settings can be edited in this section: select None, Simple or Bordered.
None Simple: only the case name Bordered: full information
With Bordered mode you can enter information into the caption. Unselect unnecessary data.
In Simple mode, a checkbox with the name of the case is placed over the image and
covers it in part, whereas in Bordered mode it is placed below it.
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3.6.10. Edit tools settings
Here you can set the preferred configuration for each tool, such as: type of character, colour etc. and store
them as default values for each new case.
Select this field to change the type of drawing system line (line section size:
recommended for routine operations with the touch screen).
On the Edit screen (see image below) it is possible to change the character type, colour and thickness of the
text and lines, but these changes are only valid for the current case.
Disable a single tool by unchecking the relevant checkbox.
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3.6.11. Preferences settings
A. AutoLive. Select the checkbox to go back to LIVE mode when an image has been acquired and
saved.
B. Auto Edit Mode. When you wish to automatically enter the Edit area after image acquisition.
C. Shutdown camera entering Edit mode. This stops the camera during image editing operations. This
function increases the camera’s lifetime. This is the default setting, please do not change it.
D. Force double entry. By checking this checkbox, every time you create a patient case, you will be
required to enter the case name twice, thereby preventing errors.
IT IS NOT POSSIBLE TO CHANGE THE CASE NUMBER AFTER ITS CREATION.
E. Live at start. Enable this option to go directly to LIVE when launching the software.
F. Audio rec. Maximum audio recording time.
G. Video rec. Maximum video recording time

H. Cam standby after. Set the time (in seconds) after which the camera goes to standby mode. This
function increases the camera’s lifetime. The initial setting is at 1h.
I. Delay for image during Present. Set the delay time between images during a presentation.
J. Max case name length. Please do not change this.
K. Reset recording video options. Press this button to delete the saved video settings. The next time a
video is acquired, the user will be asked to set the quality (see chap. 3.4.6)
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4. MacroPATH as MULTISTATION VIEWER

4.1. How to install MacroPATH as viewer
It is possible to install MacroPATH in all the desired computers without license, using the software provided
in electronic format (for example, the office of every individual pathologist).
In this case MacroPATH will only work as a viewer, simply allowing images to be retrieved, by using either
the barcode or manually entering the case name. The images can only be viewed but not edited.
To carry out any edits on the images (such as adding notes, sections etc.), a MacroPATH software license
must be available. Contact your local dealer.
MacroPATH as viewer is the same software installed on the MacroPATH unit and it does not need a new
license. Therefore, the user is authorised to install MacroPATH software as Viewer on any PC.
For license activation see chapter 3.6.3.
MacroPATH Viewer can be installed on any computer: using the MacroPATH USB key and open the
MacroPATH folder. Click on Set Up installer and follow the instructions set out in chapter 2.7 to proceed with
MacroPATH software installation.
The first time MacroPATH is installed on a PC the FULL feature license is provided for a
trial period of 90 days free of charge. After 90 days, if a license is not activated you will
only have access as MacroPATH Viewer. Refer to chapter 6.20 for further information on
licenses.
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4.2. PC settings for MacroPATH Viewer
Milestone strongly recommends that the following procedures be carried out by your local
Network/IT Manager.
Before proceeding with the following instructions, it is required to connect the PC with the
licensed MacroPATH software installed and the PC with MacroPATH Viewer to the local
network, setting it with appropriate parameters (see chapter 3.6.4)
MacroPATH Viewer can access files acquired by the laboratory-installed MacroPATH only if both have the
same saving folder set in Setting storage, as per these instructions:
1. Launch MacroPATH viewer

2. Click the “Settings” icon on the screen
3. In the Storage window click on the first Browse button as shown:
\\SERVER\Pathological Anatomy\Laboratory\MacroPath\IMAGES
4. Set the same address contained in Setting storage of the laboratory’s MacroPATH.
For correct installation it is essential to enter the server folder shared by the MacroPATHs
in the first address, as shown in the figure
It is now possible to work from two (or more) work stations. When a new case is added from the histological
laboratory, every additional work station is able to view and print the same images.
Milestone strongly recommends storing the files on a server with an automated backup
procedure. Contact your local Network/IT Manager.
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4.3. Integrating MacroPATH with LIS systems
The MacroPATH software offers perfect integration with the LIS systems. Different methods can be used to
perform the integration:
➢ TWAIN protocol
To use the TWAIN protocol, refer to chapter 3.6.7.
➢ Command row
With the simple command string, the LIS system is able to start MacroPATH to support the “workflow”.
The command that LIS can send to MacroPATH consists of two parts: the connection to the MacroPATH
software and the patient identification code (ID).
For example:
from the default installation directory
MacroPATH software can run:
C:\Program Files (x86)\Milestone srl\Macropath5\ Macropath
Patient ID: abc
The full command will be:
With this command the MacroPATH software is launched automatically by immediately opening patient file
“abc”.
The user can directly acquire all necessary files: photos, audio, video, which will be saved in the file storage
folder (in this example “abc”) and kept in the selected saving directory (see “Storage” in the “Setting” menu).
When these operations are completed, the patient data will be available for the LIS system.
Important note for Command Row

To import data into the LIS system there needs to be an additional application to manage
the patient folder based on customer requests.
This function is normally already enabled in the LIS configuration.
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Flow and requirements for integration with command row:
Command row with

patient ID
The folder identified with

patient ID is created in
the saving directory
Data are imported by an

additional application in
the LIS system
Shared folder
For each patient, the software creates a specific folder identified with file name/number containing all of the
images, audio and video created with MacroPATH.
Additionally, the software also creates the XML file of the session in this folder, with a lot of information,
including: Patient ID, file opening and closing time.
How MacroPATH saves the images
For each specific case it is required to enter the file name/number, using the software’s interface, by
manually typing it with the keyboard or using the barcode reader. MacroPATH does not automatically
generate any identification code for the file, so to start the system the user is required to enter the specimen
identifier file name/number.
The MacroPATH system can also receive the file name/number directly from the LIMS system.
Image acquisition
Refer to chapter 3.4.6.
Where and how images are saved:
MacroPATH files are saved (by default) in the path/directory:

C:\Users\Public\Documents\Milestone srl\MacroPath5\IMAGES
By default, this directory is created in the hard-disk C, but the archive can be saved wherever you wish. We
strongly recommend placing the Images folder in a different position on the local network (refer to chapter
3.6.4).
The example provided below shows how 5 images taken from file ABC are saved in the directory
(C:\Users\Public\Documents\Milestone srl\MacroPath5\IMAGES)
All the images are saved in .JPG format. The MacroPATH software automatically saves the images with the
ID name (file name) as shown below:
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ABC_0001.JPG
ABC _0002.JPG
ABC _0003.JPG
ABC _0004.JPG
ABC _0005.JPG
All the images are then available to be recovered and displayed by any other software.
The XML file shown below was created automatically for the ABC file used in this example:
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The generic structure of the file folder is shown below:
Patient ID
Audio
PatientID_001 PatientID_002 PatientID_003
.mp3 .mp3 .mp3
Video
.avi .avi .avi
thumbs
.jpg .jpg .jpg
m5p
.m5p .m5p .m5p
Native image
file
PatientID.wmark
Watermark images
PatientID_001
.jpg
PatientID_002 High resolution file

.jpg images
PatientID_003
.jpg
Session_PatientID
.xml Session log
LIS can therefore import data from the folder through the “shared folder” mode.
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5. MAINTENANCE
5.1. MacroPATH cleaning up

The procedure described in this chapter must be performed on a daily basis.
For reasons of safety, any operation without the required personal protection equipment
is to be avoided.
MacroPATH decontamination is mandatory due to the biohazard, in view of the use of

fresh specimens.
5.2. Safety precautions
The personnel involved in decontamination of MacroPATH and optional parts (if any) must wear personal
protective equipment, specifically:
• HI-RISK type single-use protection gloves (100% latex or equivalent material). Personal protection
system compliant with standard EN 374 and Directive 89/686/EEC.
• Antibacterial mask for surgical/operating theatre use and white coat. Personal protection system
compliant with standard EN 149 Grade FFP3D and Directive 89/686/EEC.
5.2.1. PC Screen and Camera
DISCONNECT THE PLUG FROM THE SOCKET BEFORE STARTING THE CLEANING UP
PROCEDURE
During normal use the PC Panel may get soiled and should, therefore, be cleaned regularly.
Cleaning up agents: soap and detergents.
Cleaning up steps:
1. Prepare agent as per the manufacturer’s instructions or hospital protocol,
2. Wipe the PC Panel with a clean cloth that has been moistened in the cleaning solution,
3. Clean thoroughly with a clean cloth.
Do not soak or rinse the PC, its peripherals or the camera.
Do not use abrasive cloths to clean the camera lenses.
Should you accidentally spill liquid on the device, disconnect the unit from the power
source.
Contact your clinical engineering service in relation to the safety of the unit before
operating it again.
Do not spray cleaning agents on the chassis.
Do not use disinfectants that contain phenol.
Do not autoclave or clean the PC Panel or its peripherals with strong aromatic,
chlorinated, ketone, ether or esther solvents (such as ethyl acetate or methyl palmitate),
sharp tools or abrasives.
Never soak electrical connectors in water or other liquids.
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5.2.2. Keyboard and mouse
To clean the keyboard and mouse while they are connected, lock the keyboard by holding down “Locking
Key” for three seconds.
Clean the surface of the product by brushing it, spraying it or soaking it. Only use cloths, sponges or soft-
bristle brushes.
DO NOT soak the USB connector in liquid.
Clean with a dry cloth or let it air dry.
Release the keyboard by holding down “Locking key” for three seconds.
Recommended disinfectants:
• Chlorine-based (max 10% solution) – Chlorox, Novalsan, etc.
• Phenol-based – Lysol I.C., Beaucoup, Magna Clean, Tek-Trol, etc.
• Alcohol-based – Cavicide, Isopropyl Alcohol, Medicide, etc.
• Oxidant-based – 3% Hydrogen Peroxide solution, Lifegard Series, etc.
• Quaternary ammonium – Roccal-D, Bacto-Sep, Parvosol, etc.
• Water and soap.
DO NOT USE: petroleum-based fluids such as Petrol, Fuel Oil, Acetone, exceeding 10% solution with
bleach, sterilisation temperatures or pressures, polishing or abrasive sponges.
5.2.3. Foot pedal control
The foot pedal buttons can be cleaned with agents and disinfectants commonly used in hospitals.
5.2.4. Touch-Pen
1. Use 99.5% denatured alcohol and alcohol-based decontaminating disinfectants.

2. Clean the Touch-pen with a clean cloth that has been moistened in the cleaning solution,
3. Clean thoroughly with a clean cloth.
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6. OPTIONAL PARTS
We advise against using parts that are not supplied by Milestone.
6.1. Table top camera holder
CODE DESCRIPTION Q.TY IMAGE

370455 Table stand for camera. It 1
also includes the
MACROSTAND WA (REF STAND
370285 – see 6.15).
The table top camera holder
is also compatible with
MACROSTAND XL (REF
370606 – see 6.15) which
must be ordered separately
MACROSTAND
WET AREA
For installation, connect the macrostand base, as shown in the figure below. Use the six screws and the
Allen wrench included.
Then connect the Camera to the table stand.

Loosen the 13 screws of the white panel and insert the cables internally. Place the white panel back on.
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The final configuration is pictured below:
The overall dimensions of the unit are: L 40cm x H 83cm x D 41cm. (15” x 32” x 16”)
The images shown are only an example
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6.2. Camera holder for hood type Grossing Station

370440 Clamp support to mount the 1
camera on a shelf
75
Secure the shelf clamp to the camera by using the front holes with the 2 M6x40 screws (with washers and
nuts) supplied.
Alternatively, rotate the support as shown in the picture using the top holes with the 2 M6X16mm screws
(with washer) provided.
Remove the knobs and turn the support by 180° and secure to the bracket with the 2 M6x16mm screws
provided.
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6.3. “C” bracket for MacroPATH camera

370488V “C” support for ceiling/wall 1
camera mounting
Secure the ceiling bracket to the camera by means of the front holes with the 2 M6x40 screws (with washers
and nuts) supplied.
Alternatively, rotate the support as shown in the picture using the top holes using the 2 M6X16mm screws
(with washer) provided.
No screws are included to secure the entire unit, as this depends on the thickness and type of wall that you
need to attach it to.
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6.4. Floor Type Terminal Holder on wheels

360073 Mobile Screen/PC floor 1
support fitted with 4 caster
wheels.
It includes a keyboard
supporting surface.
Suitable for PC assembly if
there is limited space in the
hood area (with Schuko
socket)
360074 with US Socket
360075 Mobile Screen/PC floor 1

support fitted with 4 caster
wheels.
It includes a keyboard
supporting surface.
Suitable for PC assembly if
there is limited space inside
the hood area.
(without socket)
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6.5. Camera wall mount bracket

370550 Wall-mounting camera arm 1
This optional part is used to attach the camera to a masonry wall.

To secure the camera to the arm, remove the camera support.
No screws are included to secure the entire unit, as this depends on the thickness and type of wall that you
need to attach it to.
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For thin surfaces it is required to use the black plates to fasten the back-structure.
If necessary, use the extra support.
To attach the unit to the desired surface you need to prepare the surface with 6 holes for M8 screws, as in
the example:
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6.6. Tube clamp camera mount

370540 Clamping bracket for fastening 1
the camera on Ø30 to Ø50mm
round section crosspiece.
Secure the clamping bracket to the camera using the bottom holes with the 2 M6x16 screws (with washers)
supplied.
To change the distance between the camera and the surface, adjust the four screws:
Final configuration:
81
82
6.7. Camera centring plate

370552V Camera centring plate 1
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6.8. Unit consisting of 3-jointed arm with VESA plate 75x75mm and 100x100mm

370587 3-jointed arm with VESA 1
75/100 fitting with epoxy-
coated wall mounting
Maximum capacity 7.5 Kg
(screws included) with white
VESA 75/100 adapter plate
installed for camera
connection
Wall mounting
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6.9. 3-jointed arm with wall-mounting

370588 3-jointed arm with VESA 1
75/100 fitting with epoxy-
coated wall mounting
Maximum capacity 7.5 Kg
(screws included)
Wall mounting
6.10. Adapter Plate VESA 75/100mm

370611V White VESA 75/100 adapter 1
plate
To connect the camera on an
arm with VESA fitting
(screws not included)
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6.11. Reinforcement plate for VESA arm

102596V Reinforcement plate for 1
VESA arm (code 370587 and
code 370588).
To be used only if necessary.
86
Assembly order
Wall + + + + Tool with

VESA fitting
(i.e. monitor)
Wall + + + + Camera
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6.12. USB bar code readers

370059 USB Bar code reader 1D 1
(includes holder)
Barcode reader to
automatically enter the
patient/file number, to open a
new file or retrieve an
existing file.
102011 USB Bar code reader 2D 1

(includes holder)
The barcode reader is useful
for automatically entering the
file name/number or
retrieving an existing file.
This model can read the following 1D and 2D

codes:
1D (linear) Bar Codes
UPC/EAN/JAN (A, E, 13, 8); UPC/EAN/JAN (including P2 /P5);
UPC/EAN/JAN (including; ISBN / Bookland & ISSN); UPC/EAN
Coupons; Code 39 (including full ASCII); Code 39 Trioptic;
Code39 CIP (French Pharmaceutical); LOGMARS (Code 39 w/
standard check digit enabled); Danish PPT; Code 32 (Italian
Pharmacode 39); Code 128; Code 128 ISBT; Interleaved 2 of 5
; Standard 2 of 5; Interleaved 2 of 5 CIP (HR); Industrial 2 of 5;
Discrete 2 of 5; Datalogic 2 of 5 (China Post Code/Chinese 2 of
5); IATA 2of5 Air cargo code; Code 11; Codabar; Codabar
(NW7); ABC Cod-abar; EAN 128; Code 93 ; MSI; PZN;Plessey;
Anker Plessey; GS1 DataBar Omnidirectional; GS1 DataBar
Limited; GS1 DataBar Expanded; GS1 DataBar Truncated;
DATABAR Expanded Coupon.
2D Stacked Codes
It is capable of decoding the following symbols using multiple
frames (i.e. Multi-Frame Decoding):
Datamatrix; Inverse Datamatrix; Datamatrix is configurable for
the following parameters:
Normal or Inverted; Square or Rectangular Style; Data length
(1 - 3600 characters); Maxicode; QR Codes (QR, Micro QR
and Multiple QR Codes); Aztec; Postal Codes - (Australian
Post; Japanese Post; KIX Post; Planet Code; Postnet; Royal
Mail Code (RM45CC); Intelligent Mail Barcode (IMB); Sweden
Post; Portugal Post); LaPoste A/R 39; 4-State Canada; PDF-
417; MacroPDF; Micro PDF417; GS1 Composites (1 - 12);
Codablock F; French CIP13a; GS1 DataBar Stacked; GS1
DataBar Stacked Omnidirectional; GS1 DataBar Expanded
Stacked; GSI Databar Composites; Chinese Sensible Code;
Inverted 2D codesb
- a) It is acceptable to handle this with ULE
- b) The SW can apply the Normal/Reverse Decoding Control
to the following symbols: Datamatrix, QR, Micro QR, Aztec and
Chinese Sensible Code.
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6.13. USB Waterproof (sealed) keyboard

372352 Waterproof keyboard with 1
built-in touchpad, IP68
protection against water and
dust.
Available in the following
languages:
code
372352BE Belgian
372352DE German
372352ES Spanish
372352FR French
372352IT Italian
372352RU Russian
372352UK English
Portuguese keyboard
available without touchpad
code 372352PT
372402 IP65 rating Greek keyboard 1

with silicone USB cover,
without touch pad
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6.14. Keyboard support with VESA connection

370017V Keyboard support with VESA 1
connection. Weight 2Kg.
Can be used with any VESA
support (see 6.9)
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6.15. Macrostand
DESCRIPTION Q.TY IMAGE

REF 370285 MACROSTAND WA 1
Cutting surface 395mm x 295mm (15” x

11”) to reduce samples.
This cutting board must only be used
with the table camera support (see 6.1).
including:
CODE 370276
REF 370292KIT/B
CODE High density PE 1

370276 customized board A3
with steel pins and
draining channels.
Dimensions:
295x395mm (11”x15”)
REF CUTTING BOARD A3 B 1

370292KIT/B
Kit of q.ty 10 blue plastic
cutting sheet A3 with
scale (mm)
REF 370606 MACROSTAND XL 1
Cutting surface 525mm x 330mm (20” x

12”) to reduce samples. It can be used
individually or with the table stand (see
6.1) alternatively to the cutting board
included.
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DESCRIPTION Q.TY IMAGE

REF 370290 KIT CUTTING BOARD A3 1
Complete kit which includes:

CODE 370278
REF 370289
CODE A3 high density PE surface 1

370278 with feet and drainage
channels. This cutting board
includes 4 feet that make it
suitable for use on a work
bench (not recommended for
table support)
REF CUTTING BOARD A3 BGW 1

370289 which includes:
REF 370292KIT/B 1
CUTTING BOARD A3 B
10 A3 blue cutting boards
REF 370292KIT/G 1
CUTTING BOARD A3 G
10 A3 green cutting boards

REF 370292KIT/W 1
CUTTING BOARD A3 W
10 A3 white cutting boards
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6.16. Macro Stand Dry Area 230V and Macro Stand Dry Area 115V

280100 Macro Stand Dry Area 230V 1
Photographic stand for
photos in clean area with 2
daylight illuminators
36W, 5400K, 230V, 50Hz.
PXLXH 600X550x1000mm
(23” x 21” x 39”)
290100 Macro Stand Dry Area 115V 1

Photographic stand for
photos in clean area with 2
daylight illuminators
36W, 5400K,115 V,60Hz
PXLXH 600X550x1000mm
(23” x 21” x 39”)
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6.17. Foot Pedal Control

370033 Foot pedal control USB with 1
5 buttons
- IP X5
USB cable length 4.5m (49
yd)
6.18. Sizing Ruler

40219 Sizing Ruler 80 cm 1
6.19. Wire microphone

370039 Wire microphone with 3.5mm 1
1/8” jack fitting
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6.20. Licenses
MacroPATH and MacroPATH BASIC are always supplied with a FULL license valid for a single PC.
If required, extra licenses may be bought for additional PCs that MacroPATH can be installed on (for
example on office PCs), which are not required to access Viewer mode only (refer to chapter 4).
The two available licenses are:
REF 370262F MacroPATH 5 FULL
MacroPATH extra license FULL 5.X on USB key including:

- digital imaging acquisition in jpg format (only with Milestone
camera connected)
- video acquisition in AVI format (only with Milestone camera
connected)
- annotation capabilities (sizing, blocks sampling, free hand drawing
etc)
- possibility of zooming in images already saved for detailed
examination
- case report generation in RFT format suitable for WordPad or
Microsoft Word Office
- capability of importing microscopy images via Twain protocols
(only with Milestone camera connected or using the Interface
Command)
REF 370262E MacroPATH 5 EDIT
MacroPATH extra license EDIT 5.X on USB key including:

- annotation capabilities (sizing, blocks sampling, free hand drawing
etc)
- possibility of zooming in images already saved for detailed
examination
- case report generation in RFT format suitable for WordPad or
Microsoft Word Office
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6.21. Mouse wireless laser in silicone

372363 Silicone USB wireless laser 1
mouse
USB
2 AAA batteries are required (not included): use the screwdriver supplied to unscrew and close up again as
shown below:
For cleaning up and decontamination refer to chapter 5.2.2.
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6.22. POINT-OF-CARE CONTROL TERMINAL 19”

370360 POINT-OF-CARE CONTROL 1
TERMINAL (PC Monitor) with
MacroPATH Software which includes
CODE Table stand for PC 1

370538 Monitor
CODE PC Monitor power

370476 supply
CODE Touch-Pen
370361
CODE Pen support

370362
CODE 230V cable for PC
50036 power supply
CODE 115V cable for PC

50391 power supply
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6.23. Kit Camera MacroPATH

370555 Camera with lens +1,5 mounted 1
which includes:
CODE Set of 3 lenses

370554
CODE Camera Power Supply

370222
CODE Camera power supply

370241 cable 230V~
CODE Camera power supply

370052 cable 115V~
CODE White knob

370515
98
6.24. Polarised lens for Camera

370608 Ø82mm circular polariser filter 1
to reduce reflection
First fit in the polarised lens and then also screw in the lens in use
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7. TROUBLESHOOTING for MacroPATH

For correct MacroPATH operation, the user must have full access in read/write/edit mode for the following
folders:
To see the path C:\ProgramData\Milestone srl\MacroPath5\APPDATA you need to enable hidden folders.
7.1. Milestone Remote connection
If you need support for MacroPATH, and customer support requires a remote connection, follow these
instructions.
To activate the “Milestone Remote Connection”:

• the PC needs to be connected to the internet (this needs to be allowed by the Network/IT manager of
the laboratory/ hospital) and
• the Milestone Remote Connection software must be installed on the PC. Alternatively, it is possible to
have TeamViewer installed with license 5.
The Milestone Remote Connection software comes with the unit in electronic format (the
software is already installed on the PC supplied by Milestone)
The license for TeamViewer is not supplied by Milestone.
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7.1.1. How to install the Milestone Remote Connection software (for MacroPATH Basic)
Only follow this procedure if the software is not already on the PC (MacroPATH Basic).
Double click on the setup file.
Click Next when the following message appears.
Click Next when the following message appears.
Enable the checkbox shown in the picture to create a

button on the desktop and click Next.
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Click Install to start installation.
Click Finish and installation is complete.
102
7.1.2. How to start the remote connection.
Double click on the Milestone Remote Connection button on the Desktop to launch
communication. The following panel will appear.
Contact customer support at this e-mail address:customersupport@milestonemedsrl.com and provide the

following data:
• Serial number of the unit

• Version of the remote connection software
• ID
• Password
The connection can only be established if the GREEN icon appears.
The password changes every time the PC is restarted or switched off.
7.2. The camera is not working
If the camera is not working correctly, follow the procedure explained below:
• Exit the software
• Switch off the PC.
• Wait a few seconds and restart the PC.
• Wait at least 30 seconds and then relaunch the software.
If the camera continues not working:

• Exit the software
• Switch off the PC.
• Then disconnect the camera’s power supply, disconnecting the camera’s connector as pictured below.
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• Wait at least 5 seconds and then reconnect the camera connector.

• Wait a few seconds and restart the PC.
• Wait at least 30 seconds and then relaunch the software.
If the problem is not fixed, contact our Technical support department at

7.3. The Live function is not working
When MacroPATH is launched, if Live is not working, act as follows:
• Make sure the license is in Settings – Licensing. If there is none, follow the procedure to create it, as
explained in chapter 3.6.3.
• If there is a license, follow the instructions provided in the previous chapter.
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7.4. The foot pedal control is not working
Go to “Settings” through the specific icon and click on the “camera” button.
Select the serial number (each foot pedal control has its own serial number)
If two or more serial numbers are displayed, check whether any external instrument is connected using the
same drivers. However, the serial number is found on the foot pedal control. Select an appropriate serial
number, save and restart the software. If the foot pedal control is still not working, select another serial
number and repeat the previous operations.
If no serial number is displayed:
1) Install the driver contained in the MacroPATH USB key
2) Connect the foot pedal control to another USB port.
The serial number for the foot pedal control usually starts with the letters ST.
To install the drivers, close the MacroPATH software and enter the Packages folder contained in the USB
key:
Then run the last version of Footers, in this case “Footer-CDM20830”.
After installing the drivers, restart the computer and launch the software, and check whether the foot pedal
control is working.
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7.5. The Touch Pen is not working
If the pointer does not work when you touch the screen, try changing the USB port.
If the problem continues, restart the PC.
If the touch-pen continues not working, you will need to reinstall the relevant drivers contained in the USB
key with MacroPATH Software as per the following instructions:
1) Disconnect the touch-pen from the USB port
2) Open the “Touch Pen Drivers” folder and follow the information provided in the “instructions” file:
- Open folder “eGalaxWorks31xx~4378-01_test1-20180606-Getac-19inch-system” and run file

“eGalaxSensorTester3.exe” to start installation
- Do not touch the screen during installation.
- Connect the Touch-pen to the USB port and start using it
If it still is not working, contact customer support.
7.6. Touch-Pen and Touch Screen calibration
If the pointer does not move correctly when touching the screen or it does not go to the selected point,
recalibrate the touch-screen or the touch-pen as follows:
- Select the “Touchscreen calibration” icon on the desktop
or from the “Start” menu go to “Control Panel”
106
- Select “View by category” and “Hardware and Sound”
107
- In “Table PC Setting” select “Calibrate the screen for pen or touch input”
- The following window will open, click “Calibrate”:
108
- Select PEN INPUT to calibrate the touch-pen and/or TOUCH INPUT to calibrate the screen.
- Select PEN INPUT and follow the instructions that appear on the screen until the end of the procedure
109
- At the end of the procedure this final screen will appear, select YES to save the data
110
- Select TOUCH INPUT and follow the instructions that appear on the screen until the end of the procedure
- At the end of the procedure this final screen will appear, select YES to save the data
111
- If an incorrect calibration was saved, click RESET with the mouse to restore the default calibration
112
7.7. Return for repair to Manufacturer
Read the following notes carefully
This instrument is an in-vitro medical diagnostic device and it is usually installed in a laboratory where
samples and other biological tissues are present. For your safety, it must therefore be cleaned and
disinfected before use, and gloves must be worn when using this instrument.
You must wear gloves when operating the system.
If the unit needs to be returned to Milestone s.r.l. for repairs, the device must be cleaned up and disinfected
(as described in chapter 5) prior to shipment. Any units that have not been disinfected will not be accepted
and you will be contacted with regards to disinfection cost.
In accordance with international health standards, biohazard materials must be shipped in appropriate
packages (risk of fines).
7.8. PC Recovery Software
This procedure deletes all of the data and settings in the PC. The PC will go back to
the factory configuration.
This procedure will reinstall the operating system.
This procedure needs to be carried out by duly trained staff (IT Manager).
This procedure uses Clonezilla Software.
Clonezilla itself is licensed under the GNU General Public License (GPL) Version 2.
Clonezilla comes with absolutely NO Warranty.
For all the other languages, refer to the Clonezilla procedure in English.
Insert the USB key with the “Clonezilla”

software (WHITE USB port) and the key
with the images Installed (BLUE 3.0 USB
port)
Press the PC ‘on’ key

Press “Esc” or “Del” repeatedly at startup
until the blue screen appears.
113
Use the right key to go to Boot.
Set key startup as the first:
1. Boot Option #1 -> Select the USB

key with the Clonezilla Software
Press F4 and confirm
114
Start Clonezilla by pressing Enter on the

keyboard
Select English
Select “Do not change keyboard

mapping”
115
Select start Clonezilla
Select “device-image”
Select “local-dev”
116
Press enter
Press “Ctrl-C”
Select sdb1 or sdd1 (make sure

that it is the name of the key
containing the image to be
restored)
117
Select “Done”
Press Enter on the keyboard
Select beginner mode
118
Select restore disk
Select “PCAdvantech-
Multilanguage……… the image
required based on the machine.
Select the 500GB hard disk
119
Select: Yes, check the image
Select choose
Press Enter on the keyboard
120
Wait for completion
Press: Y and Enter on the

keyboard
Press: Y and Enter on the
keyboard
Press Enter
Select Poweroff and enter
Wait for switch off (7 sec)
Remove the two USB keys
Restart the PC
121
8. DISPOSAL OF THE MacroPATH UNIT

Removal of equipment in use for disposal:
1) Turn the PC off and unplug from the main power supply.
2) Turn the camera off. Unplug the camera power supply from the main socket.
3) Disconnect all optional parts (foot pedal control, keypad, bar code reader, camera, camera power
supply).
4) Clean and disinfect all parts of the equipment according to the manufacturer’s specification.
5) Dispose of all electric and electronic parts of the equipment
In compliance with directive 2012/19/EC of the European Parliament of 4 July 2012 on waste electrical and
electronic equipment (WEEE), the separate collection of the equipment is mandatory.
It is required to return the used equipment to the distributor or to inquire about the presence of a local system
for collection and disposal of electrical and electronic equipment.
Failure to comply with directive 2012/19/EC can have potential effects on the environment and human
health.
This symbol indicates separate collection

for electrical and electronic equipment
122
Milestone Srl
marketing@milestonemedsrl.com
Via Fatebenefratelli, 1/5 - 24010 Sorisole (BG) - Italy www.milestonemed.com
Tel +39 035 4128264 - Fax +39 035 575498

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MILESTONE

MacroPATH e MacroPATH Basic

Operator Manual - MM161-001

Read carefully this manual before using the instrument.

MM161-001- MacroPATH and MacroPATH Basic QX Series - Operator Manual

4.1. How to install MacroPATH as viewer .............................................................................................. 65

An instruction accompanied by this WARNING symbol means you need to proceed

CE logo: this instrument complies with European Community directives.

IVD medical device according to directive 98/79/EC.

Symbol of the European WEEE directive (2002/96/EC):

1.2. Introduction to MacroPATH and MacroPATH Basic

MacroPATH's measurement function is strictly linked to the calibration performed by the

1.3. Technical Specifications

Hardware (PC) (only for MacroPATH):

Foot pedal control

Operating temperature: 15°C – 30°C (59°F – 86°F)

1.4. Transport and storage conditions

1.5. Warning information

PERSONAL DATA SAFETY

In the event of a malfunction:

1.7. MacroPATH data backup (PICTURES OF FILES)

1.8. Milestone remote connection

1.9. MacroPATH and MacroPATH Basic labels

For the explanations of the symbols, refer to chapter 1.1.

Refer to the label attached to the device for device identification.

2.1. Unpacking and checking MacroPATH and MacroPATH Basic components

DESCRIPTION Q.ty IMAGE

Table stand for “All in one PC” 1

“All in one PC” power supply with Schuko cable 1

“All in one PC” power supply cable 1

Camera + Set of 3 lenses (lens +1,5 already 1

Camera power supply with cable included 1

115V~ Camera power supply cable NEMA 1-15 1

Foot pedal control 1

Set of Allen screws 1

Included with both MacroPATH and 1

The pictures are only an example.

For the optional parts, see Chapter 6.

2.2. Overview of PC Monitor (only for MacroPATH)

It is advisable to turn the PC off completely at least once a week.

2.3. Camera Overview

For the camera installation/clamping supports, refer to chapter 6.

2.4. Table stand installation for MacroPATH PC Monitor

Table support installation as follows:

- Use the 4 screws provided to clamp the base to the column:

2.4.1. PC Monitor connections

The power supply line needs a ground connection (Class I device)

MICROPHONE POWER SUPPLY

TOUCH PEN CAMERA

Make sure that the audio microphone switch is ON before use.

2.5. Camera Lens Installation

With these lenses it is possible to change the focusing distances.

Lens Allowed Distances Recommended

2.5.1. Camera Orientation

2.5.2. Camera connections

Connect the power supply as pictured:

Connect the USB data cable to the relevant PC USB port.

Power supply line protection: 10A - C curve circuit breaker

Connect the cable to the power supply and to the mains.

Not applicable for MacroPATH Basic.