Quiz Lipids and Lipoproteins

In diagnostic significance of cholesterol, there is a direct relationship between
elevated serum cholesterol and myocardial infarction. *

True
False
When triglycerides (TAGs) are metabolized , their fatty acids are released to the cells
and converted into energy – provide excellent insulation. *
True
False
Since only 3–5% of the fatty acids in serum are unesterified, this procedure to
determine the esterified fatty acids is often satisfactory as measure of the total fatty
acids of serum. *
True
False
Stool with normal and 1+ amounts of fatty acids may show as many as 100 tiny
globules per HPO with diameters between 1–4 micra. If the amount is 5+ there is
clinical steatorrhea. *
True
False
The polyunsaturated and cis-monosaturated fatty acids are associated with elevated
serum LDL cholesterol. *
True
False
Large amount of fatty acids is present in plasma (free unsterified form), less is bound
to albumin. *
True
False
Apo AI in combination with Apo AII and Apo CI is responsible for the removal of free
cholesterol from extrahepatic tissues. *
True
False
Phospholipid is the most abundant lipid derived from phosphatidic acid. *

True
False
Lipogenesis provide the substance for conversion to glucose. *
True
False
Excess cholesterol is re-esterified by the microsomal enzyme acyl : cholesterol acyl

transferase (ACAT) and is stored until it is needed. *
True
False
Chromatographic methods utilizes either Gel Chromatography of Affinity

Chromatography. *
True
False
TAG and cholesterol are the most important lipids in the management of coronary
artery disease (CHD). *
True
False
LDL-Z is currently considered the most important value in assessing cardiac risk and
directing therapy. *
True
False
In fatty acids, the classification As to Chain is a saturated (without double bonds) fatty
acids or unsaturated (with double bonds) fatty acids. *
True
False
Intermediate Density Lipoprotein (IDL) is a product of VLDL catabolism – “VLDL

remnant”. *
True
False
The four major lipoproteins classes can be identified based on Particle size, Chemical
composition, Flotation characteristics, physicochemical properties and
Electrophoretic mobility. *
True
False
Familial Lipoprotein Lipase Deficiency is also known as Familial Chylomicronemia. *
True
False
Phospholipids are linear chains of carbon-hydrogen bonds that terminate with a

carboxyl group. *
True
False
Esterified fatty acids –5%; Free fatty acids –95% *

True
False
One of the functions of lipids is to participate in cellular metabolism and blood

coagulation. *
True
False
When apoproteins complexed into lipoprotein particles, they are referred to as

apolipoproteins. *
True
False
The uptake into tissue cells and subsequent oxidation into acetyl Co–A which can be
further, oxidized to carbon dioxide and water via the Kreb’s or monocarboxylic acid
cycle take place. *
True
False
The most hydrophobic lipids, such as fatty acids and phospholipids, are located in the
core of the lipoprotein particle. *
True
False
Free Fatty Acids are determined by titrating with alkali after direct extraction with a
non–polar solvent. *
True
False
CETP connects the forward and reverse triglyceride transport pathways. *

True
False
It is the breakdown or hydrolysis of the substance such as triglycerides into fatty acids
and glycerol occurs through the action of the lipase. *
It is present when elevated plasma lipoproteins have been clinically important in the
genesis of atherosclerosis and pancreatitis *
Reference value for fatty acids. *
These are protein units found in lipoproteins but not yet incorporated into their
respective lipoprotein particles. *
Very high triglyceride has a reference value of __. *
It is referred to as diseases associated with abnormal lipid concentrations. *
In the principle of total fatty acids, it is extracted by refluxing with alcohol–ether and
the extract is saponified with KOH. The fatty acids are precipitated, separated and
titrated with standard KOH. *
Cholesterol and triglycerides travel in plasma not as free-floating molecules, but as

part of water-soluble complexes called __. *
It is a rare autosomal recessive disorder characterized by complete absence of HDL

due to a mutation in the ABCA1 gene on chromosome 9. *
It is a form of phospholipid attached to a choline particle. *
It is a major lipoprotein and the largest and least dense of the lipoprotein particles. *
This disorder is inherited as an autosomal dominant trait. The defect appears to be an

inability to synthesize ApoB–100 and ApoB–48. *
It is a polar nonesterified alcohol. *
It can be used during the extraction step to remove interfering substances. *
It is found on the surface of lipid layers and synthesized in the liver. *
Abetalipoproteinemia is also known as __. *
It is one of the complications in arteriosclerosis wherein if a bulge in the wall of an

artery bursts, it can cause a slow leak or life-threatening internal bleeding. *
It is a type of apoprotein that functions in the activation of lipoprotein lipase (LPL),

leading to the breakdown of triglycerides at the cellular level, with subsequent release
of fatty acids to the cells for metabolism and storage. *
In this pathway, the production of TAG from FA by the liver take place, with synthesis
of VLDL particles containing apo B100 and apo E. *
These are linear chains of carbon-hydrogen bonds that terminate with a carboxyl
group. *
It is also known as density gradient and is the reference method for quantitation of
lipoproteins (LPPs). *
They released TAG to adipose tissue as they circulate. *
What do you call the process for conversion of a substance to glucose? *
It contains 3 molecules of fatty acid and one molecule of glycerol by ester bonds. *
It is an abnormal lipoprotein found in obstructive jaundice & LCAT deficiency. *
A form of phospholipid that has an abundant sphingolipid in cellular membranes: its

hydrolysis releases ceramide and phosphocholine and several stimuli are known to
activate sphingomyelin hydrolysis. *
It is a test for lipid that used to detect derangement of lipid metabolism and for
assessing susceptibility to atherosclerosis and coronary heart disease. *
It aids in the solubilization of the lipids and also in their transfer from the
gastrointestinal tract to the liver, which contains specific receptors for
apolipoproteins. *
Apolipoprotein contains a structural motif called __. *
The presence of this and hydroxyl group in the sterol’s structure makes it possible for
cholesterol to carry out a colorimetric assay. *
It is a recessive disorder wherein plant sterols are absorbed and accumulate in
plasma and peripheral tissues. *
Fatty acids are mostly found as constituents of phospholipids and _. *
The Saponification + Extracton + Colorimetry + Precipitation is under on what step

method? *
Also known as free fatty acids. *
In fatty acids, the __ and cis-monosaturated fatty acids are not associated with
elevated serum LDL cholesterol. *
Cholesterol increases with age, with women having lower values than men before the
age of what? *
It is an amphipathic lipd, which means it contains polar hydrophilic (water-loving) head

groups and non-polar (water-fearing) fatty acid chains - the saturated fatty acid
content of plasma phospholipids is is reported to be an independent risk factor for
atherosclerosis. *
It is a lypolytic enzyme that hydrolyzes TAG and phospholipids from HDL; hydrolyzes
lipids on VLDL and IDL. *
An enzymatic method in triglyceride that involves hydrolysis of triglycerides to free

fatty acids and glycerol, followed by the phosphorylation of glycerol to
glycerophosphate. *
It is the end product of Salkowski Reaction in the chemical methods of cholesterol. *
Each mole of phosphorus contributes about __ to the total Phospholipid mass; thus,
phospholipid mass can be determined by multiplying the phospholipid phosphorus
concentration expressed in mg/dL) by 25. *
It is estimated from the evaluation of pulmonary surfactant in amniotic fluid - the

lecithin/spingomyelin ratio (L/S) and phosphatidyl glycerol (PG) by chromatography or
the microviscosity by fluorescence polarization are used. *
It is the smallest lipoproteins but the most dense. *
It uses antibodies specific to epitopes on the apolipoproteins. *
These are large macromolecular complexes of lipids with specialized proteins known
as apolipoproteins. *
These are commonly referred to as fats, composed mostly of carbon-hydrogen

bonds. *
Lipolytic mobilization is promoted by Growth hormone, Glucagon,

Adrenocorticosteroid and ___. *
It is a lypolytic enzyme wherein it catalyzes the esterification of cholesterol from HDL;

enables HDL to accumulate cholesterol as cholesterol ester. *
An average person ingests, absorbs, resynthesizes, and transports about 60g-__ of fat
daily in the body, mostly in the form of triglycerides. *
Where does Cholesterol ester transfer protein produced? *
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In diagnostic significance of cholesterol, there is a direct relationship between

elevated serum cholesterol and myocardial infarction. *

Phospholipid is the most abundant lipid derived from phosphatidic acid. *

Excess cholesterol is re-esterified by the microsomal enzyme acyl : cholesterol acyl

Chromatographic methods utilizes either Gel Chromatography of Affinity

Intermediate Density Lipoprotein (IDL) is a product of VLDL catabolism – “VLDL

Phospholipids are linear chains of carbon-hydrogen bonds that terminate with a

Esterified fatty acids –5%; Free fatty acids –95% *

One of the functions of lipids is to participate in cellular metabolism and blood

When apoproteins complexed into lipoprotein particles, they are referred to as

CETP connects the forward and reverse triglyceride transport pathways. *

Reference value for fatty acids. *

Very high triglyceride has a reference value of __. *

It is referred to as diseases associated with abnormal lipid concentrations. *

Cholesterol and triglycerides travel in plasma not as free-floating molecules, but as

It is a rare autosomal recessive disorder characterized by complete absence of HDL

This disorder is inherited as an autosomal dominant trait. The defect appears to be an

It is a polar nonesterified alcohol. *

It can be used during the extraction step to remove interfering substances. *

It is found on the surface of lipid layers and synthesized in the liver. *

Abetalipoproteinemia is also known as __. *

It is one of the complications in arteriosclerosis wherein if a bulge in the wall of an

It is a type of apoprotein that functions in the activation of lipoprotein lipase (LPL),

They released TAG to adipose tissue as they circulate. *

What do you call the process for conversion of a substance to glucose? *

It is an abnormal lipoprotein found in obstructive jaundice & LCAT deficiency. *

A form of phospholipid that has an abundant sphingolipid in cellular membranes: its

Apolipoprotein contains a structural motif called __. *

Fatty acids are mostly found as constituents of phospholipids and _. *

The Saponification + Extracton + Colorimetry + Precipitation is under on what step

Also known as free fatty acids. *

It is an amphipathic lipd, which means it contains polar hydrophilic (water-loving) head

An enzymatic method in triglyceride that involves hydrolysis of triglycerides to free

It is estimated from the evaluation of pulmonary surfactant in amniotic fluid - the

It is the smallest lipoproteins but the most dense. *

It uses antibodies specific to epitopes on the apolipoproteins. *

These are commonly referred to as fats, composed mostly of carbon-hydrogen

Lipolytic mobilization is promoted by Growth hormone, Glucagon,

It is a lypolytic enzyme wherein it catalyzes the esterification of cholesterol from HDL;

Where does Cholesterol ester transfer protein produced? *

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