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BP 801t Biostatistics and Research Methodology Jun 2020

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Total No. of Questions : 8] [1] [Total No. of Printed Pages : 3

Roll No ..................................

BP-801T/PY-801-CBGS
B.Pharmacy VIII Semester (PCI Scheme)/
(Non-PCI Scheme)
Examination, June 2020
Choice Based Grading System (CBGS)
Biostatistics and Research Methodology
Time : Three Hours
Maximum Marks : 75
Note: i) Attempt any five questions out of Eight questions.
ii) All questions carry equal marks.

1. a) Find the Mean, Median and Mode of the following data:


2, 4, 7, 1, 6, 9, 5, 4, 4, 3, 4
b) Define Range and Standard deviation. Find the Standard
Deviation of the data:
1.24, 5.19, 1.62, 9.54, 2.63, 4.25, 5.34

2. a) The monthly rate for a certain disease is 7 in 1000. What


is the probability for just 2 deaths on account of this
disease in a group of 400? Given that e–2.8 = 0.06.
b) The Height of 10 males of a given locality are found to be
70, 67, 62, 68, 61, 68, 70, 69, 64, 66 inches. Is it
reasonable to believe that the average height is 64 inches?
Test at 5% significance level for 9 degree of freedom.
(Given t0.05 = 1.83 for 9 d.f.)

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[2]

3. a) What do you meant by Research? Explain experimental


design techniques.
b) Discuss various phases in designing clinical trial with
examples.

4. a) What is meant by regression modelling? Explain hypothesis


testing in simple and multiple regression models.
b) Explain Blocking and Confounding the 2k factorial design
in two blocks.

5. a) What do you meant by factorial design? Write some


advantages of factorial design.
b) Write short note on central composite design.

6. a) Find the Karl Pearson’s coefficient of correlation from


the following data:
x 2 4 4 7 5
y 8 8 5 6 2
b) Define the following:
i) Null hypothesis and Alternative hypothesis
ii) Error I-Type and Error-II type
iii) Sampling and Essence of sampling

7. a) For the given data


x y
Arithmetic Mean 36 85
Standard Deviation 11 8
Correlation coefficient between x and y is 0.66. Find two
regression lines of-
i) y on x
ii) x on y

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b) Explain the following


i) Cohorts studies
ii) Report writing and presentation of data

8. a) The table below shows the hours of relief provided by


two analgesic drugs in 12 patients suffering from arthritis.
Is there any evidence that one drug provides longer relief
than the other. Use Wilcoxon Rank Sum test to solve
Drug A 2.0 3.6 2.6 2.6 7.3 3.4 14.9 6.6 2.3 2.0 6.8 8.5
Drug B 3.5 5.7 2.9 2.4 9.9 3.3 16.7 6.0 3.8 4.0 9.1 20.9
Given that P-Value, P = 0.012
b) Write short note on ANOVA (Analysis of Variance).

******

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