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Generic Name: Ibuprofen Brand Name: Advil, Ibutab, Midol Classification: Analgesics

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Generic Name: Ibuprofen Brand Name: Advil, Ibutab, Midol Classification: Analgesics

Therapeutic Use Anti-inflammatory, analgesic and antipyretic activities largely related to inhibition of prostaglandin synthesis; exact mechanisms of action are not known. Inhibits both cyclooxygenase (COX) 1 and 2. Ibuprofen is slightly more selective for COX-1.

Indication Relief of signs and symptoms of rheumatoid arthritis and osteoarthritis Relief of mild to moderate pain Prevention and treatment of migraine headache Treatment of primary dysmenorrheal Fever reduction

Contraindication Contrainidicated with allergy to ibuprofen, NSAID, salicylates (common in patiets with asthma, rhinitis, chronic urticaria, and nasal polyps) To be used cautiously with hypertension, GI bleeding, peptic ulcer, impaired renal or hepatic function, pregnancy, or lactation.

Side Effects Nausea GI upset Dyspepsia Diarrhea or constipation Drowsiness Dizziness Vertigo Insomnia

Nursing Responsibilities Administer drug with food or meals if GI upset occurs. Arrange for periodic Ophthalmologic examination for long-term drug use. Discontinue drug if eye changes, symptoms of liver dysfunction or renal Impairment occurs. Instruct patient to use the drug as suggested and to avoid over-the counter medications (many OTC drugs contain similar components which may lead to overdose). Instruct patient to report mouth sores, fever, chills, weight gain, changes in vision, swelling in ankles or fingers, and black, tarry stools. Instruct patient to limit activities to those that do not require

Generic Name: Acetaminophen Brand Name: Aceta, Anacin, Cetafen Classification: Analgesic Therapeutic Use Antipyretic: Reduces fever by acting directly on the hypothalamic heat-regulating center to cause vasodilation and sweating, which helps dissipate heat. Analgesic: Site and mechanism of action unclear Indication Temporary reduction of fever, temporary relief of minor aches and pains caused by common cold and influenza, headache, sore throat, toothache (patients ages 2 yr and older), backache, menstrual cramps, minor arthritis pain, and muscle aches (patients older than 12 yr) Unlabeled use: Prophylactic use in children and patient at risk Contraindication Contraindicated with allergy to acetaminophen. Use cautiously with impaired hepatic function, chronic alcoholism, and pregnancy, lactation Side Effects GI upset Headache Nursing Responsibilities Do not exceed the recommended dosage. Consult physician if needed for children <3 yr; if needed for longer than 10 days; if continued fever, severe or recurrent pain occurs (possible serious illness). Avoid using multiple preparations containing acetaminophen. Carefully check all OTC products. Give drug with

for seizures who are receiving DPT vaccination to reduce incidence of fever and pain.

food if GI upset occurs. Discontinue drug if hypersensitivit y reactions occur. Treatment of overdose: Monitor serum levels regularly, Nacetylcysteine should be available as a specific antidote; basic life support measures may be necessary

Generic Name: Brand Name: Classification: Narcotics

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