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    Questions of Moodle Final 2019

    Uploaded by

    Miki Abera
    The document appears to be a collection of immune-related questions and answers. It includes questions about types of immune responses, immunoglobulins, complement pathways, and immunity to various microbes. The questions cover topics ranging from antibody structure and function to mechanisms of allergy and hypersensitivity.

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    © All Rights Reserved
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    Questions of Moodle Final 2019

    Uploaded by

    Miki Abera
    53 views6 pages
    The document appears to be a collection of immune-related questions and answers. It includes questions about types of immune responses, immunoglobulins, complement pathways, and immunity to various microbes. The questions cover topics ranging from antibody structure and function to mechanisms of allergy and hypersensitivity.

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    © © All Rights Reserved

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    The document appears to be a collection of immune-related questions and answers. It includes questions about types of immune responses, immunoglobulins, complement pathways, and immunity to various microbes. The questions cover topics ranging from antibody structure and function to mechanisms of allergy and hypersensitivity.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    53 views6 pages

    Questions of Moodle Final 2019

    Uploaded by

    Miki Abera
    The document appears to be a collection of immune-related questions and answers. It includes questions about types of immune responses, immunoglobulins, complement pathways, and immunity to various microbes. The questions cover topics ranging from antibody structure and function to mechanisms of allergy and hypersensitivity.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    You are on page 1of 6

    Final - 2019

    Immune questions :
    ( it is all with in the lects , direct question )

    84. ABO incompatablity & good pasture syndrome -> type ll sesnstivity reaction

    85, Membrane attcak-> c5b


    Chemotaxsis -> c5a
    Yaka lawana bu naznam kama bu ☝ 🏻

    86. Which cell participate in la alternative pathway -> Mets cell & basophils

    88. Major surface lg of Immature B cell -> lgD

    89. Agglutination & activation of complex -> lgM

    90. J chain -> lgA

    91. Mast cell & basophils -> igE

    92. Role in type 1 hypersensitive (allergy ) -> LgE

    96. Which one has primary respond for viral infection


    Ans// IG A

    97. Which one is artificial active acquired immunity


    Ans// vaccination

    98. Which one is not a character of immunogen


    Ans// low molecular weight

    99. Dimeric ==> IgA2

    100. Involve in differentation of B- cells ==> IgD


    Questions of Moodle
    Lec 1 \\ Introduction to immunology
    Q1\ Cytokines are high molecular weight soluble glycoproteins that play an important role as
    immune mediators.
    A. True
    B. False

    Q2\ Mononuclear phagocytes in connective tissue known as:


    A. mesangial cells
    B. Histocyte
    C. Monocytes
    D. Kupffer cells

    Lec 2\\ Innate immunity


    Q1\ Lysozyme in tears, nasal secretions, and saliva consider an example on one of the following
    answers:
    A. Chemical factor
    B. Biological factor
    C. Mechanical factor

    Q2\ Toll-like receptor play the main role in specific immunity.


    A. True
    B. False

    Lec 3\ Antigen

    Q1\\ The following related to the characteristic of immunogen except one of them:
    A. Heteropolymers composed of different amino acids or sugar are more immunogenic
    B. Homopolymers are more immunogenic than the heteropolymers molecules.
    C. The most active immunogens tend to have a molecular mass above 100,000 Daltons.
    D. More foreignness substance it is meaning more antigenic.
    Q2\\ Lipids usually are not antigenic but may act as haptens.
    A. True
    B. False
    Lec 4\ Antibody
    Q1\ B-cell antigen receptor complex consist of one of the following answers
    A. (IgM and IgA)
    B. (IgM and IgD)
    C. (IgM and IgE)
    D. (IgM and IgG)
    Q2\ The class switching does not affect the antibody’s specificity for its antigen.
    A. True
    B. False
    (Explanation \ During ab switching, the constant region of the heavy chain is changed, but not
    the variable region)
    Q3\ The most immunoglobulin in body secretion is one of the following:
    A. IgE
    B. IgG
    C. IgM
    D. IgA
    Q4\ IgG has many biological functions EXCEPT one of them:
    A. Minor Immunoglobulin crosses placenta.
    B. Agglutination activity
    C. Coplement fixation
    D. Opsonization
    (Explanation\ Major Immunoglobulin crosses the placenta)

    Lec 5\ Adaptive immunology

    Q1\\ Vaccination is an example on one of the following types of immunity

    A. Artificial passive adaptive immunity B.


    B. Natural active acquired immunity
    C. Natural passive adaptive immunity
    D. Artificial active acquired immunity

    Q2\\ Humoral immunity mediated by cytotoxic cells.

    A. True
    B. False
    Lec 6\ Hypersensitivity
    Q1\\ One of the following immunoglobulin responsible for Allergic reaction
    A. IgG
    B. IgA
    C. IgE
    D. IgM

    Q2\\ late-forming mediators cause symptoms as erythema and indurations.


    A. True
    B. False

    Q3\\ Conditions under which cytolytic reactions take place include all of the following except one
    of them
    A. New antigens as a result of drug-induced changes
    B. Antigenic determinant on host cell that is identical or very similar to self-antigen
    C. Antigen structural component of a cell membrane or an extrinsic antigen that has attached
    to the cell
    D. Antigen-antibody complexes that have formed in circulation and subsequently attached to
    red blood cells

    Q4\\ Serum sickness is a local vasculitis associated with the deposition of immune complexes and
    activation of complement.
    A. True
    B. False

    Q5\\ The delayed type of hypersensitivity transferred by sensitized B cells,


    A. True
    B. False
    Lec 9\\ Immunity to microbes 1
    Q1\\ Macrophage-dependent cellular immunity by binding of antibody coated bacteria to the
    macrophage via surface receptors for the Fab.
    A. True
    B. False

    Q2\\ Mycobacterial cell wall rich in lipid which elicit strong immune response including one of
    the following:
    A. Type II hypersensitivity
    B. Type IV hypersensitivity
    C. Type III hypersensitivity
    D. Type I hypersensitivity

    Q3\\ Intracellular bacterial pathogens reside in phagocytic cells so it shielded from the immune
    response by interference with oxidative killing like Leishmania donovani,
    A. True
    B. False

    Lec 10\\ Immunity to microbes 2


    Q1\\ Viruses with short incubation period as influenza virus, IgM is the predominant Ig.
    A. True
    B. False

    Q2\\ Cells that are supporting viral replication express viral antigen fragments in association with
    MHC class I molecules that lead to lysis of the infected cell by CD4 T cells.
    A. True
    B. False

    Q3\\ One of the following mechanisms that used by virus to escape from immune system is true
    except one of them:
    A. Long incubation period
    B. None or only limited amounts of antigen on the surface of the cells they infect.
    C. Antigenic stabty
    D. Persist
    Q4\\ Some viruses reduce expression of HLA class I on their surface as adenovirus to escape from
    immune system.
    A. True
    B. False
    Lec 11\ Complement system 1
    Q1\\ Amplification phase result is activation one of the following component
    A. C5
    B. C3
    C. C2
    D. C1
    Q2\\ The first component of membrane attack complex is one of the following
    A. C3b
    B. C4b
    C. C5b
    D. C2b

    Q3\\ C5b play important role in adhesion neutrophil to the endothelial cells.
    A. True
    B. False

    Lec 12\ Complement system 2


    Q1\\ Properdin is a protein that stabilizes C3bBb complex leading to less C3b generation.
    A. True
    B. False

    Q2\\ Mannan binding lectin is a protein play important role in Alternative pathway
    A. True
    B. False

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