Histopathology P1 & P3
Histopathology P1 & P3
Histopathology P1 & P3
SESSION 1
7. It is characterized by the formation of a gelatinous (gel-like) substance in dead tissues in which the
architecture of the tissue is maintained, and can be observed by light microscopy.
A. Fat necrosis B. Coagulative C. Gangrenous D. Fibrinoid
8. What is the term used to define diseases as well as deaths attributed to the Physician?
A. Nutritional Derangements B.Psychogenic Diseases C.Iatrogenic Causes D.Idiopathic Diseases
10. These are terms that used to define cases wherein there is lack of supply of blood or of oxygen in the
Body.
A. Hypoxia B. Ischemia C. Both D. Neither
SESSION 2
1. The term used for the heat felt at the area of inflammation
A. Tumor B. Calor C. Dolor D. Rubor
3. Watery fluid seen in the cavity using a microscope is characteristic of what type of Exudate?
A. Fibrinous B. Catarrhal C. Suppurative D. Serous
4. What type of Inflammation is usually seen in Pleural, pericardial and Peritoneal surfaces?
A. Catarrhal B. Purulent C. Hemorrhagic D. Fibrinous
5. Type of inflammation wherein large amounts of pus is produced.
A. Suppurative B. Phlegmonous C. Hemorrhagic D. Catarrhal
10. Vesicles, Pox, burns of second degree are under what type of Exudate?
A. Fibrinous B. Catarrhal C.Serous D. Purulent
11. Incomplete/defective development of a tissue/organ most commonly seen in one paired structure.
A. Aplasia B. Hypoplasia C. Agenesia D. Atresia
13. Reversible change involving transformation in one type of adult cell to another
A.Anaplasia B. Dysplasia C. Metaplasia D. Neoplasia
14.Continuous abnormal proliferation of cells without control (usually with no purpose or function)
A.Anaplasia B. Dysplasia C. Metaplasia D. Neoplasia
15. This generally consists of an expansion of immature cells, with a corresponding decrease in the
number and location of mature cells.
A.Anaplasia B. Dysplasia C. Metaplasia D. Neoplasia
19. It is an encapsulated tumor with tissue or organ components resembling normal derivatives of all
three germ layers.
A. Meratoma B. Teratoma C. Carcinoma D. Pangtoma
1. Normally found from puberty, after childbirth, with abortion and menopause
A. parabasal cell
B. Navicular cell
C. Intermediate cell
D. Pregnancy cells
3. Found 1-10 days after menstruation and are shed in response to ovarian hormones
A. Endometrial
B. mature superficial
C. Intermediate cell
D. Pregnancy cells
9. Honeycomb appearance:
A. Koilocytes
B. Basal cells
C. Intermediate cells
D. Endocervical glandular
10. You can visualize a group of parabasal cells in these situations except for:
A. 2 weeks of age to puberty
B. After menopause
C. After child birth
D. Before menopause
SESSION 4
4. Which of the following is the preferred equipment for tending to a person who is not breathing?
A. Defibrillator
B. Resuscitation bag and mask
C. Mouth to mouth resuscitation
D. Vicks VapoRub
5. All of the following are toxic materials capable of causing death in small doses, except:
A. Methanol B. Chromic acid C. Osmium tetroxide D. Dihydrogen monoxide
6. Which of the following is a required basic information that should be seen on the labels of chemicals?
A. Hazard warnings
B. Nutritional value
C. sp orbital of the chemicals
D. boiling point
7. Resting the wrist or forearm against the sharp edge and corner is an example of what ergonomic risk
factor?
A. Awkward postures
B. Duration
C. Repetition
D. Contact stress
10. They cause allergic reactions in some exposed workers, not just in hypersensitive individuals.
A. Corrosives
B. irritants
C. Sensitizers
D. Carcinogens
SESSION 5
It is done by placing a drop of secretion or sediment upon one slide and facing it to another clean slide.
A. Touch prep
B. Pull-apart
C. Smear
D. Squash
E. Teasing prep
2. Cryostat is a cold chamber used for Frozen sections and is usually kept at what temperature?
A.-5-25 degrees C
B. -0-10 Degrees C
C. 10-30 Degrees C
D. -10-20 Degrees C
4. Vital stains can be used for what fresh tissue examination method?
A. Teasing
B. Spreading
C. pull apart
D. Touch prep
6. This type of smear preparation is especially recommended for smear preparations of fresh sputum
and bronchial aspirates?
A. Spreading
B. Pull-apart
C. Streaking
D. touch prep
7. This type of Smear preparation has an added advantage of examining the cells without destroying
their intercellular relationship.
A. Spreading
B. Pull-apart
C. Streaking
D. touch prep
9. It is the simplest, least invasive surgical procedure for procuring the needed sample for fresh tissue
examination.
A. Core needle
B. Trephination
C.. Fine needle
D. Curetting
10. The technique involves the use of a circular blade that is rotated down through the epidermis and
dermis, and into the subcutaneous fat, yielding a 3-4 mm cylindrical core of the tissue sample.
A. Shave
B. Punch
C. Fine needle
SESSION 6
4. All of the following are suitable factors that may speed up the process of tissue processing, Except:
A. Increased agitation
B. Increased temperature
C. Thinner tissue sections
D. Reduced pressure
5. What is the usual buffer used for maintaining the optimum pH of Formaldehyde solutions?
A. Magnesium
B. Calcium oxalate
C. Picric acid
D. Phosphate
6. Dehydration of the tissues with ethanol is done in _____________ to facilitate proper water removal.
A. Decreasing concentration
B. Increasing concentration
C. Same concentrations
D. Any concentration
8. The temperature of the warm bath should be kept at __________ the melting point of the wax.
A. 5-10Oc
B. 10-15oC
C. 20oC
D. 3oC
9. They are the most commonly employed embedding media for semi-thin and ultrathin section.
A. Prosthetics
B. Acrylics
C. Epoxy
D. Celloidin
10. What is the most common clearing agent used in the histopath laboratory?
A. Acetone
B. Xylene
C. Benzene
D. Porthuene
SESSION 7
1. Using the Rapid Microwave processing removes what step in tissue processing?
A. Clearing B. Dehydration C.Fixation D. Infiltration
2. Microwave processing can be ________ faster than conventional processing time with an hourly
throughput of up to 120 specimens.
A. 50% B. 70% C. 100% D. 250%
3. The optimum temperature for staining methods using metallic compounds in RTP is ________.
A. 75-95 C B. 80-105 C C. 65-75 C D. 55-60 C
4. One of the main advantages of using automated microwave processing compared to the conventional
kitchen type microwaves is:
A. Less toxic wastes
B. Less consumption of electricity
C. More precise maintenance of temperature
D. Uneven distribution of heat in the tissue
6. This type of smear preparation is especially recommended for smear preparations of fresh sputum
and bronchial aspirates?
A. Spreading
B. Pull-apart
C. Streaking
D. touch prep
7. This type of Smear preparation has an added advantage of examining the cells without destroying
their intercellular relationship.
A. Spreading
B. Pull-apart
C. Streaking
D. touch prep
9. It is the simplest, least invasive surgical procedure for procuring the needed sample for fresh tissue
examination.
A. Core needle
B. B. Trephination
C. Fine needle
D. Curetting
10. The technique involves the use of a circular blade that is rotated down through the epidermis and
dermis, and into the subcutaneous fat, yielding a 3-4 mm cylindrical core of the tissue sample.
A. Shave
B. Punch
C. Fine needle
D. curetting
SESSION 8
1. This Method of fixation is primarily used to accelerate other forms of fixation as well as the next steps
in processing.
A. Freezing B. Heat C. Vapor fixation D. Secondary Fixation
8. What is the preferred thickness of a tissue section to be examined using electron microscope?
A. 1-2 mm2 B. 5 cm2 C. 1 cm 2 D. 0.9 cm2
SESSION 9
1. Polymerized form of formaldehyde, usually obtained as a fine white powder, which depolymerizes
when heated
A. Paraformaldehyde B. Metaformaldehyde C. Glutaraldehyde D. Karnovsky’s solution
2. Recommended for preservation of CNS tissues and general post-mortem tissues for histochemical
examination
A. 10% NB Formalin B. 10% Formol saline C. Gendre’s D. Formal-sublimate
5. Which of the following is a Nuclear and a Histochemical fixative at the same time?
A. Newcomer’s B. Flemming’s C. Acetone D. Regaud’s
10. Which of the following is included in the formula for 10% Neutral buffered formalin?
A. Sodium Dihydrogen Phosphate B. Disodium Hydrogen Phosphate C. Distilled water D. all of the
choices
SESSION 18
1. A related procedure to Staining that makes use of Heavy metal salts which precipitates on certain
cellular and tissue Components.
A. Infiltration B. Staining C. Blueing D. NOTA
2. This serves as a link or bridge between tissue and the dye to make staining reaction possible.
A. Accentuator B. Mordant C. Stain D. Counterstain
3. A reagent not essential to the chemical union of the tissue and dye. It does not participate in the
staining reaction.
A. Accentuator B. Mordant C. Stain D. Counterstain
4. The process whereby tissue elements are stained in a definite sequence and the staining solution is
applied for specific periods of time.
A. progressive B. regressive C. Degressive D. Decolorization
7.Use of dyes which differentiate substance in a section by staining them with a color that is different
from the stain Itself.
A. Regressive staining B. Progressive C. Orthochromatic D. Metachromatic
8.It is the application of a different color or stain to provide contrast and background.
A. Overstaining B. Counterstaining C.Metastaining D. Decolorization
SESSION 19
1. It is recommended for staining Triglycerides, giving them an Intense red stain.
A. Sudan III B. Sudan IV C. Sudan Black D. Oil Red O
7. Used as a contrast stain for Gram’s Technique, in acid fast and Papanicolau method.
A. Congo Red B. Neutral red C. Victoria blue D. Bismarck brown
13. It is the Staining solution most commonly used for Routine Histologic studies.
A. Orcein B. Eosin C. Hematoxylin D. Wright’s
14. Aside from Eosin Y, which of the following is/are also forms of Eosin?
A. Eosin B B. Eosin S C. Eosin D D. A and B C. B and C
16. What dye is Normally Colorless but when treated with ammonia and exposed to air, produces blue
or violet colors?
A. Hematoxylin B. Cochineal C. Coal Tar D. Orcein
17. What is added to Chromogen to improve the retaining of color?
A. Chromophore B. Decolorizer C. Auxochrome D. Lysochrome
SESSION 20
1. Van Gieson’s Acid fuchsin-Picric acid stain will dye the collagen fibers with what color?
A. Pink B. Deep Red C. Both D. Neither
3.Carmine stain, when combined with Alum chloride, can be used to stain?
A. Proteins B. Histones C. Myelin sheath D. Glycogen
8. This method is selective but not as highly specific for glycogen as the PAS method with or without
diastase.
A. Azure B B. Best Carmine C. Toluidine Blue D. Mucicarmine
9. A good quality Schiff’s reagent should be made from __________rather than Basic fuchsin
A. Rosanilin B. Pararosanilin C. Magenta II D. Azure B
14. Fat: Brilliant red, Nuclei- Blue. What is the stain being referred to?
A. Borohydride-Periodic Schiff B. Nile red sulfate C. oil Red O D. Peracetic Acid-Alcian blue
16. It is the property of tissues to be stained with fat or oil-soluble dyes, regardless of the type used, due
to their essential lipid nature.
A. Lysochromia B. Sudanophilia C. Sudanephilia D. Lysophilia
17. They are esters of fatty acids with alcohols and are usually found in the body as energy stores in
adipose tissue.
A. Simple Lipids B. Derived Lipids C. Compound Lipids D. Complicated Lipids
20. It is not a dye but is an unstable oxide which is reduced to a permanent black substance by
unsaturated fats and fatty acids
A. Sudan IV B. Oil Red O C. Borohydide-PAS D. Osmic acid
SESSION 21
2.It is a mixture of picric acid and Acid fuchsin for the demonstration of Connective tissues.
A. Von kossa’s B. Von ebner’s C. Van gieson’s D. Van Gogh
4. Amyloid- Red on a Clear background, Nuclei- Blue. What is the stain being referred to?
A. Highman’s Congo red B. Verhoeff’s C. Krajian’s D. PTAH mallory’s
5. Nissl subs- Puple dark blue, Neurons pale blue, Cell Nuclei- Purple blue.
A. Weigert-pal B. Cresyl fast violet C. Sevier-Munger technique D. Rapid toluidine blue
6. It is a common laboratory technique used to make many copies of a particular region of DNA.
A. In-situ Hybridization B. PCR C. RT-PCR D. Western Blot
SESSION 22
1. Which of the following is not demonstrated in Proteolytic enzyme method of Antigen retrieval?
A. Light chain Igs B. Heavy Chain Igs C. Complement D. Specific Epitopes
8. All of the following are helpful in the diagnosis of Fibrohistiocytic tumors except?
A. CD68 B. FAM 56 C. CD31 D. Alpha-Antitrypsin E. C and D
SESSION 23
1. Term used for Post mortem lividity and purplish discoloration.
A. Algor mortis B. Livor mortis C. Rigor mortis D. Caynosis
8. Process of taking pieces of tissue from a dead person for the purpose of examination or investigation
A. Forensic sampling B. Autopsy C. Necropsy D. Antemortem examination
9. The cadaver is opened from both shoulder regions down to the xiphoid area, then incised down to the
pubic region.
A. U-Incision B. T-Incision C. Y-Incision D. Straight Cut incision
10. A person died of unknown disease; the physician would like to know the final diagnosis. Who is
authorized to give consent for autopsy?
A. The Deceased himself
B. The attending physician
C. Next of kin or the nearest relative
D. NBI officials must perform the autopsy