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ITD77731 - CPL Diagnostic

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Visit ID : ITD77731 Registration : 05/Apr/2024 07:59PM

UHID/MR NO : ITD.0000076773 Collected : 05/Apr/2024 08:00PM


Patient NAME : Mr.DHANANJAY Received : 05/Apr/2024 08:05PM
Age/Gender : 33 Y 0 M 0 D /M Reported : 06/Apr/2024 04:59PM
Ref Doctor : Dr.ATUL KULSHRESTHA [MS ORTH STATUS : Final Report
Sec.Ref Doctor : SELF CLIENT Detail : COUNTER/0
Barcode NO : 10121648 CLIENT ADD : Agra

DEPARTMENT OF MOLECULAR PATHOLOGY


Test Name Result Unit Bio. Ref. Range Method

HLA B27 REAL TIME PCR


Sample Type : WHOLE BLOOD EDTA
PCR RESULT NOT DETECTED~NOT DETECTED REAL TIME PCR
DETECTED
Interpretation:
• A ‘Detected’ result will show the presence of HLA B27.
• A ‘Not-Detected’ result will show the absence of HLA B27.

Intended Use:
The test is designed for use as an aid in diagnosis of HLA-B27 associated disease in patients.

Description:
This is a qualitative analysis for detection of HLA B 27 DNA in clinical specimen. The detection is based on the principle of DNA
amplification of specific sequences by Real Time PCR.

The human leukocyte antigen (HLA) is well known as genetic factor for disease sensitivities and plays a key role in transplantation,
transfusions and parentage test. The HLA B27 is closely related to Ankylosing spondylitis (AS) which can cause inflammation of
the spondylarthritis and pericoxitis such as inflammatory rheumatic disease.The 90% of Ankylosing spondylitis patients have the
HLA B27 genes and normal person also has that of 5-7%.

The HLA-B27 subtype, whose frequency in the worldwide population is extremely variable; differ from each other by one or a few
amino acids, and they bind overlapping peptide repertoires. Worldwide population-based studies indicate that, among the widely
distributed subtypes, HLA-B27:02, B27:04 and B27:025 are strongly associated with Ankylosing spondylitis.

*** End Of Report ***

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Test Performed at: CLINICAL PATHOLOGY LAB AGRA

CLINICAL PATHOLOGY LAB AGRA

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