Question bank solution based on MCQs 2021-22

(Subject Code: BP 301 T)

Class: S Y B Pharmacy SEM III
Name of Subject: Pharmaceutical Organic chemistry II

& Paper Code: BP 301 T

1) ____________is the number which expresses in milligrams the amount of A
potassium hydroxide necessary to neutralise the free acids present in 1 g of the
substance.
A. Acid value B. Rancidification value
C. Diazotization D. Saponification value
2) Predict the name of the product when benzene reacts with (HNO3/H2SO4 C
A. Nitro benzoic acid B. 3-nitrobenzoic acid
C. Nitrobenzene D. Ortho Para dinitrobenzene
3) Complete hydrolysis of triglycerides yield_______ molecule(s) of glycerol and C
_________ molecule(s) of fatty acids.
A. three and one B. one and two
C. one and three D. three and two
4) Which one of the following is an unsaturated fatty acid? B
A. Lauric acid B. Linoleic acid
C. Palmitic acid D. Stearic acid
5) The amount of free fatty acids present in an oil or fat is indicated by its- D
A. saponification value B. iodine value
C. RM value D. acid value
6) Which one of the following constant is mainly used for the analysis of butter? C
A. Acid value B. saponification value
C. RM value D. iodine value
7) Which of the following esters produces butyric acid and phenol on hydrolysis? C
A. Butyl benzonate B. Phenyl propionate
C. Phenyl butyrate D. Benzyl propionate
8) The liberation of CO2 in form of bubbles on treatment with NaHCO3 indicates B
presence of _________ functional group in given compound
A. amines B. carboxylic acids C. aldehyde D. esters

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9) Which of the following is of special value in testing the (adulteration or) purity D
of butter and desi-ghee?
A. Acid number B. Iodine number
C. Saponification number D. Richert-Meissel number
10) The number of OH groups in fats can be expressed as ___________ D
A. Reichert-Meissil number B. Iodine number
C. Polenske number D. Acetyl number
11) Saponification is hydrolysis ____________ C
A. In digestive tracts of human beings B. By acids
C. By alkalis D. By salts
12) Rancidity of lipids or fat rich food is due to A
A. oxidation of fatty acids B. hydrogenation of unsaturated fatty acids
C. reduction of fatty acids D. dehydrogenation of saturated fatty acids
13) Partial Hydrogenation of vegetable oils in presence of Ni catalyst at 200'C gives A
A. Vanaspati ghee B. Margarine C. both a and b D. None of these
14) Sodium benzoate on heating with soda lime (CaO/NaOH) results in formation of C
A. sodium phenoxide B. benzaldehyde C. benzene D. benzophenone
15) lipid oils can be converted to solid fats by____________ B
A. hydrolysis B. hydrogenation
C. oxidation of double bonds D. decarboxylation

16) Which of the statements is not true about acid value C

A. used to measure the degree of hydrolytic rancidity
B. gives indication about edibility of the lipid
C. acid value of edible oil should be <1%
D. pharmaceutical oil must not have acidity

17) Which of the molecular formula given below corresponds to that of an C

unsaturated fatty acid?
A. C16H33COOH B. C19H39COOH C. C18H35COOH D.
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 Question bank solution based on MCQs 2021-22
(Subject Code: BP 301 T)
C17H35COOH
18) Fats in presence of moisture, warm temperature or bacterias are converted into B
glycerols and fatty acids, this is called _______
A. oxidative rancidity B. hydrolytic rancidity
C. catalytic rancidity D. None of the above
19) Which of the following is TRUE about saponification number? A
A. The shorter the chain length of fatty acids; the higher is the saponification
number
B. The shorter the chain length of fatty acids; the lower will be the saponification
number
C. The higher the chain saturation of fatty acids; the lower will be the
saponification number
The lower the chain saturation of fatty acids; the higher will be the saponification
number
20) Richert-Meissel number is defined as the volume of 0.1M KOH solution B
required for the neutralisation of _______ gram/grams of fat or oil.
A. 1 B. 5 C. 100 D. 1000
21) The process of hydrogenation of tryglycerides of unsaturated fatty acids into C
saturated glycerides is called
A. drying B. rancidification C. hardening D. saponification
22) With respect to the electrophilic aromatic substitution of benzene which of the B
following is not true?
A. A non-aromatic intermediate is formed
B. Benzene acts as an electrophile
C. A proton is lost in the final step
D. Resonance forms are important
23) Which of the following statements is incorrect about aromatic compounds? B
A. Are planar B. Have 4n π-electrons
C. Are cyclic D. Are generally less reactive than similarly substituted
alkenes
24) When considering electrophilic aromatic substitution reactions electron D
withdrawing substituents (e.g. nitro) are described as-

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 A. Ortho/Para directing and activating
B. Ortho/Para directing and deactivating
C. Meta directing and activating
D. Meta directing and deactivating
25) Distilling phenol over zinc dust results in the formation of? A
A. Benzene B. bromophenol C. nitrophenol D. bromobenzene
26) When considering electrophilic aromatic substitution reactions the halides are B
described as-
A. Ortho/Para directing and activating
B. Ortho/Para directing and deactivating
C. Meta directing and activating
D. Meta directing and deactivating

27) Which of the following is an example of fats? B

A. Glyceryl trioleate B. Vegetable ghee C. Coconut oil D. Groundnut oil

28) C-C bonds formed in benzene by: C

A. Sp-S overlapping B. Sp2-Sp overlapping
C. Sp2-Sp2 overlapping D. S-Sp2 overlapping
29) For reactions of ethyl benzene; ethyl group is considered as: B
A. Ortho director B. Ortho Para director
C. Ortho meta director D. meta director
30) Catalyst used in nitration reaction of benzene is? D
A. Catalyst AlCl3 B. Catalyst FeCl3 C. UV Light D. Conc. H2SO4
31) Benzene reacts with acetyl chloride in presence of AlCl3 to give C
A. Chlorobenzene B. Toluene C. Acetophenone D. Acetanilide
32) In chlorination of benzene; AlCl3 is used to generate; B
A. Cl (-) B. Cl (+) C. Cl2 D. HCl
33) Which of the following is used as Sweetener? C

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 Question bank solution based on MCQs 2021-22
(Subject Code: BP 301 T)
A. DDT B. BHC C. Saccharin D. Chloramine
34) The melting points of even-numbered-carbon fatty acids __________ with chain D
length and ___________ according to unsaturation.
A. decrease; decrease B. decrease; increase
C. increase; increase D. increase; decrease
35) The esterification of a Carboxylic acid (fatty acids) by heating it with an alcohol B
in the presence of a strong acid as the catalyst and the reaction type is
A. Electrophilic Aromatic Substitution B. Nucleophilic Acyl Substiution
C. radical substitution D. Electrophilic Aliphatic Substitution
36) which of the following can not be used as antioxidant to preserve fats and oils D
A. butylated hydroxyanisole B. propyl gallate
C. butylated hydroxytoluene D. sodium amalgum
37) Oils with an iodine number ____________ are considered non-drying. C
A. equal to its molecular weight B. 115 to 130
C. less than 115 D. more than 130

38) An increase in Iodine Value indicates high susceptibility of lipid to oxidative C

rancidity due to
A. stability B. reactivity
C. high degree of unsaturation D. formation of stereoisomers
39) The high acidic strength of para nitro benzoic acid is due to; D
A. - I (inductive effect) B. + I (inductive effect)
C. -R (resonance effect) D. - I (inductive effect) and -R (resonance effect)
40) Attachment of -Cl (chloro) group at para position in benzoic acid will; A
A. increase acidity B. decrease acidity
C. not effect on acidity D. can't say
41) Benzoic acid on reaction with thionyl chloride will form? B
A. Benzyl chloride B. Benzoyl chloride
C. Benzylic chloride D. Benzene chloride
42) N-Methylbenzamide can be synthesized from benzoic acid and? B

5 P.T.O.
 A. Ammonia B. Methyl amine
C. Dimethyl amine D. Ethyl amine
43) Predict the name of the product when benzoic acid reacts with (HNO3/H2SO4)? C
A. nitro benzoic acid B. 1,2- dinitrobenzoic acid
C. 3-nitrobenzoic acid D. 1,4- dinitrobenzoic acid
44) For the synthesis of naphthalene which two reagents are required? D
A. toluene and succinic acid B. toluene and succinic anhydride
C. Benzene and succinic acid D. Benzene and succinic anhydride
45) How many resonance structures are there for Phenanthrene? B
A. 6 B. 5 C. 4 D. 3
46) Naphthalene undergoes oxidation with Na2Cr2O7/H2SO4 to form B
A. Benzoic acid B. Phthalic Acid
C. Tetralin D. Phenylacetic acid
47) Which of the following is NOT the use of triphenyl methane C
A. used in synthesis of dyes
B. inhibits 3-methylcholanthrene induced neoplastic transformation of loti cells
C. used as industrial strength adhesive
D. its red color trityl anion is used as indicator
48) In naphthalene, bond length between C1 and C2 (1.36A) has _________ C
whereas; bond length between C2 and C3 (1.42A) has___________
A. more 𝞂 character; more 𝝅 character
B. less 𝝅 character; less 𝞂 character
C. more 𝝅 character; more 𝞂 character
D. less 𝞂 character; less 𝝅 character
49) Aspirin is produced by heating salicylic acid with _______ A
A. Acetic anhydride in presence of phosphoric acid
B. benzoic anhydride in presence of phosphoric acid
C. methyl alcohol in presence of sulphuric acid
D. phenol in presence of sulphuric acid

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 Question bank solution based on MCQs 2021-22
(Subject Code: BP 301 T)
50) Anthracene undergoes sulfonation with concentrated sulfuric acid to yield a D
mixture of 1- and 2- anthracene sulfuric acid. In this reaction formation of major
product is ______
A. independent of external factors
B. kinetically controlled
C. controlled by catalyst
D. thermodynamically controlled
51) Friedel crafts condensation between 1 mol benzyl chloride and 1 mol benzene B
gives
A. naphthalene
B. diphenyl methane
C. triphenyl methane
D. benzophenone
52) Methyl benzoate on hydrolysis will form ________________ B
A. acetic acid B. benzoic acid C. picric acid D, phenylacetic acid
53) Phenanthrene can be prepared from D
A. Coal tar
B. Haworth Method
C. Posher Synthesis
D. all of the above
54) Addition reaction in phenanthrene preferentially takes place at_____________ A
A. 9,10 position B. 3,4 position C. 7,8 position D. 1,2 position
55) What is the product when anthracene is treated with sodium dichromate and B
sulfuric acid?
A. 9-Nitroanthracene B. 9,10-Anthraquinone
C. 9,10-dihydroanthracene D. 2-anthraquinone sulfonic acid

56) The carboxylic group of benzoic acid is C

A. electron withdrawing and ortho para directing
B. electron releasing and meta directing

7 P.T.O.
 C. electron withdrawing and meta directing.
D. electron releasing and ring deactivating

57) Sodium phenoxide reacts with CO2 at 120-140°C under 5 bar pressure, reaction D
is called:
A. Perkin reaction B. Wurtz reaction
C. Riemer Tiemann reaction D. Kolbe reaction
58) Number of milligrams of KOH required to neutralize fatty acid present in 1 gm B
of fat is called-
A. Potassium number B. Acid value
C. saponification value D. Iodine value
59) Use of phenol is in- C
A. alcoholic beverages B. an anaesthetic
C. antiseptic D. insect repellent
60) Electrophilic substitution on naphthalene occurs preferentially at? B
A. 2 carbon B. 1 carbon
C. 9 carbon D. 10 carbon

61) Treatment of phenol with chloroform in aqueous sodium hydroxide D

solution followed by acid hydrolysis to form salicyladehyde is known as-
[A]Kolbe Reaction [B]Gatterman Reaction
[C]Fries rearrangement [D]Reimer-Tiemann Reaction
62) Almost all the chemical reactions of phenanthrene occur across- B
[A] 3,4- bond [B] 9,10-bond [C] 5,6-bond [D] 7,8-bond
63) Which of the following substituent is meta director? B
[A]NH2 [B]NO2 [C]OH [D] Cl
64) The angle strain is maximum in case of- D
[A]Cycloheptane [B]Cyclopentane [C]Cyclohexane [D]Cyclopropane
65) The phenomenon in which two or more structures can be written for a B
substance which involve identical position of atom is called as-
[A]Isomerism [B]Resonance [C]Epimerization [D]Tautomerism

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 Question bank solution based on MCQs 2021-22
(Subject Code: BP 301 T)
66) Electron releasing alkyl substituent that is para or meta to the carboxyl B
group increases the acidity of benzoic acid.
[A] TRUE [B] FALSE
67) Which of the following statement is false? C
[A] Oils and fats are colorless, odorless & tasteless
[B] Oils and fats have lower specific gravity than water
[C] Oils and fats are soluble in water and insoluble in organic solvents
[D] Alkaline hydrolysis of fats and oils is known as saponification
68) Oxidation of naphthalene in presence of KMnO4 gives- A
[A]Pthalic acid [B]Naphthaquinone [C]Phthalaldehyde [D]Phthalic
anhydride
69) Anomalous behavior is the property of – D
[A]Actinides [B]Lanthanides [C]Nobel gases [D]Halogens
70) The bond angle between carbon atom in cyclohexane is- C
[A]60o [B]90o [C]109o28' [D] 120o
71) Which of the following is simplest polynuclear hydrocarbon? D
[A]Benzene [B]Anthracene [C]Azulene [D] Napthalene
72) Which of the following is used as a food preservative? A
[A]Sodium Benzoate [B]Benzyl alcohol [C]Ethyl benzoate
[D]Benzotrichloride
73) Hoffman –martius Rearrangement is given by- C
[A]Aromatic acids [B]Benzene [C]Aromatic amines [D]Phenols
74) Synthesis of cycloalkanes from ester of dicarboxylic acids is also known B
as-
[A]Friedal Craft Method [B]Dieckmann method
[B]Simmons- Smith method [D]Hoffman-martius method
75) Benzene reacts with alkyl halides in presence of aluminium chloride to D
form alkylbenzenes is known as-
[A] Ozonolysis [B] Friedel-crafts Acylation
[C] Halogenation [D] Friedel-crafts Alkylation

9 P.T.O.
76) Which of the following is used as a fragrance in perfumes, soaps and C
shampoos?
[A]Naphthalene [B]Anthracene [C]Diphenylmethane
[D]Triphenylmethane
77) Benzoic acid reacts with alcohols in the presence of concentrated sulfuric D
acid to form-
[A]Amide [B]Acid [C]Ether [D]Ester
78) Acylation of aromatic amines with acid halides or anhydrides results in B
the formation of-
[A]Imines [B]n-arylamides [C]Primary amines [D]Diazonium salts
79) Hardening of oils refers to- A
[A]Hydrogenation [B]Hydrolysis [C]Hydrogenolysis
[D]Rancidification
80) Cyclobutane can be reperesented by- A
[A] Square [B]Triangle [C]Hexagon [D]Pentagon
81) Which of the following is angular polynuclear hydrocarbon? C
[A]Anthracene [B]Naphthalene [C]Phenanthrene
[D]Diphenylmethane
82) Acid hydrolysis of phenyl cyanide gives- A
[A]Benzoic acid [B]Benzoyl chloride [C]Ethylbenzene [D]Ethyl
benzoate
83) Compound containing –OH group attached directly to an aromatic ring B
are known as-
[A]Alcohols [B]Phenols [C]Aromatic Alcohols [D]Carboxylic acids
84) Which of the following is not one of the methods of preparationof D
aromatic amines?
[A]Reduction of azo compounds [B]Amonolysis of aryl chlorides
[C]Reduction of nitro compounds [D]Oxidation of alkylbenzene
85) Cycloalkanes are also called as- C
[A]Alicyclic compounds [B]Acyclic compunds
[C]Cycloparaffins [D]Aromatic alkanes

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 Question bank solution based on MCQs 2021-22
(Subject Code: BP 301 T)
86) The uncharged, lipophilic molecules made up of fused multiple aromatic A
rings containing carbon and hydrogen atoms only are called-
[A]Polynuclear Hydrocarbons [B]Heterocyclic compound
[C]Benzocyclic compounds [D]Mononuclear hydrocarbons
87) Which of the following compound obeys huckel rule? A
[A]Benzene [B]Cycloheptatriene [C]Cyclooctatriene [D]None of
these
88) What is the common name of o-aminobenzoic acid? D
[A]Pthalic acid [B]Toluic acid [C]Salicyclic acid [D]Anthranilic acid
89) Aromatic amines are less basic than aliphatic amines. A
[A]TRUE [B]FALSE
90) Which of the following statement is wrong? B
[A]Aromatic amines are colourless liquids or solids
[B]Aromatic amines have relatively low boiling points
[C]Aromatic amines are sparingly soluble in water
[D]Aromatic amines are highly toxic substances
91) The process of chopping of animal tissue containing fat are chopped off D
and heated dry or with water until fat melts is called as-
[A]Pressing [B]Solvent Extraction [C]Melting [D]Rendering
92) Toluidine is more basic than aniline. A
[A]TRUE [B]FALSE
93) Primary aromatic amines reacts with ethanolic potassium hydroxide and D
chloroform to form-
[A]Imines [B]Salt [C]Nitrosoamine [D]Carbylamines
94) Benzoic acid is colourless solid soluble in hot water. A
[A]TRUE [B] FALSE
95) Which of the following is the effect of electron withdrawing substituent C
on acidity of phenol?
[A]Acid weakening [B]Neutral [C]Acid strengthening [D]Meta
directing
96) All ortho substituents increase acidity of benzoic acid. A
[A]TRUE [B]FALSE
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97) Behaviour of aromatic compounds containing alternate single and double A
bond resembling to benzene is called as-
[A]Aromaticity [B]Resonance [C]Hybridization [D]Isomerism
98) Benzoic acid reacts with phosphorous pentachloride or thionyl chloride C
to form-
[A]Ethyl benzoate [B]Sodium benzoate
[C]Benzoyl chloride [D]Benzyl alcohol
99) Alkaline hydrolysis of fats and oils is also known as- B
[A]Hardening [B]Saponification [C]Rendering [D]Pressing
100) Cyclopropane can be represented simply as- D
[A]Hexagon [B]Square [C]Circle [D]Triangle
101) Melting and boiling points of cycloalkanes shows gradual increase with B
decrease in molecular weight.
[A]TRUE [B] FALSE
102) Which of the following is also known as Dow process? D
[A]Preparation of phenol from Cumene
[B]Preparation of Phenol from Sodium Benzenesulfonate
[C]Preparation of phenol from Benzenediazonium salt
[D]Preparation of phenol from Chlorobenzene
103) Which of the following polynuclear hydrocarbon is non benzenoid? B
[A]Biphenyl [B]Azulene [C]Naphthalene [D]Anthracene
104) The substituent which activates the aromatic ring to further substitution is A
called as-
[A]Ring activator [B]Ring deactivator [C]Ring director [D]Ring
substitutor
105) Which of the following polynuclear hydrocarbon can be used as adhesive D
and sealant?
[A]Naphthalene [B]Anthracene [C]Triphenylmethane
[D]Phenanthrene

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 Question bank solution based on MCQs 2021-22
(Subject Code: BP 301 T)
106) Which of the following statement is wrong about benzene? B
[A]Benzene is colourless liquid.
[B]Benzene is soluble in water
[C]Vapours of benzene are highly toxic
[D]Benzene burns with sooty flame
107) Fats are composed of solid triesters of glycerol, while oils are composed A
of liquid triesters of glycerols at room temperature.
[A]TRUE [B]FALSE
108) The reaction of phenol with benzoyl chloride is known as- B
[A]Dows process [B]Schotten-Baumann reaction
[C]Gatterman Reaction [D] Friedel-crafts Alkylation
109) Which of the following is not a source of fats or oils? D
[A]Cotton seeds [B]Castor beans [C]Coconuts [D]Grains
110) Phenol reacts with bromine water to give precipitate of- A
[A]2,4,6-tribromophenol [B]1,3,5-tribromophenol
[C]bromobenzene [D]2,4-dibromophenol
111) Vapour phase oxidation of benzene in the presence of Vanadium C
pentoxide forms-
[A]Benzene hexacholride [B]Cyclohexane
[C]Maleic anhydride [D] Acetic anhydride
112) Phenols are much more acidic than Carboxylic acids but are less acidic B
than alcohols.
[A]TRUE [B]FALSE
113) Hydrogenation of glyceryl trioleate forms- A
[A]Glyceryl tristearate [B]Glyceryl trilaurate
[C]Glyceryl tripalmitate [D]Glycerol
114) Benzene cannot be prepared from- D
[A]Acetylene [B]Sodium Benzoate [C]Chlorobenzene [D]Sodium
acetate

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115) When phenol is treated with conc. Sulphuric acid at 100 oC _________ is C
the main product.
[A]m-Phenolsulfonic acid [B] o-Phenolsulfonic acid
[C] p-Phenolsulfonic acid [D]None of the above
116) Number of miligrams of KOH required to saponify one gram of fat or oil B
is called as-
[A]Iodine number [B]RM value
[C]Saponification number [D]None of the above
117) Which of the following substituent acts as a ring activator for D
monosubstituted benzene?
[A]-NO2 [B]-COOH [C]-Cl [D]-OH
118) Phenols with addition of few drops of neutral ferric chloride solution give C
which colour?
[A]Brick red [B]Yellow [C]Purple [D]White precipitate
119) Rancidification of fat or oil caused by which of the following reaction? D
[A]Oxidation [B]Reduction [C]Hydrolysis [D]Both A and C
120) Benzene has cyclic, planer and hexagonal structure having all sp2 A
hybridized carbon atoms.
[A]TRUE [B] FALSE

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