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    Ramiso 1

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    trialnumber0

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    © All Rights Reserved
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    Ramiso 1

    Uploaded by

    trialnumber0
    11 views2 pages

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    ramiso1

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    11 views2 pages

    Ramiso 1

    Uploaded by

    trialnumber0

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    of 2

    RAMISO, ADRIAN MARCO L.

    T 3:00PM-11:00PM
    BSN 2D FAMED September 12, 2023

    Cilostazol

    MEDICATION MODE OF INDICATION CONTRAINDICATION ADVERSE/SIDE NURSING


    ACTION EFFECTS INTERVENTIONS/C
    ONSIDERATIONS

    Generic Thought to To reduce •Contraindicated in CNS: dizziness, • Beneficial effects


    Name: inhibit the symptoms of patients hypersensitive headache, vertigo. may not be seen for
    Pletal enzyme intermittent to drug or its up to 12 weeks after
    phosphodie claudication. components. CV: palpitations, therapy starts.
    sterase III, peripheral edema,
    Brand Name: thus Adults: 100 Boxed Warning: tachycardia. • Monitor patients for
    Pletal® inhibiting mg PO b.i.d. Contraindicated in development of a
    platelet patients with HF of any EENT: pharyngitis, new systolic murmur
    aggregation Adjust-a- severity. rhinitis. or cardiac signs or
    and dose: symptoms after drug
    DOSAGE: causing Decrease • Contraindicated in Gl: abnormal stools, initiation.
    50mg, 100mg vasodilation dose to 50 patients with hemostatic diarrhea, abdominal
    . mg PO b.i.d. disorders or active pain, dyspepsia, Boxed Warning:
    when giving bleeding, such as flatulence, nausea. Cilostazol and similar
    Route: with drugs bleeding peptic ulcer drugs that inhibit the
    PO that may and intracranial Hematologic: bleeding. enzyme
    interact to bleeding. Musculoskeletal: back phosphodiesterase
    Onset: cause an pain, myalgia. decrease the
    Unknown increase in • Use cautiously in likelihood of survival
    (Indications cilostazol patients with severe Respiratory: increased in patients with class
    may have a level (such as underlying heart cough. III and IV HF.
    rapid onset fluconazole, disease; also use
    or a omeprazole, cautiously with other Other: infection. Alert: CV risk is
    delayed ticlopidine, drugs having antiplatelet unknown in patients
    onset) diltiazem, activity. who use drug on
    erythromycin, long-term basis and
    Peak: itraconazole, • Use cautiously in in those with severe
    Unknown ketoconazol). patients with severe underlying heart
    renal impairment (CrCl disease.
    Duration: less than 25 mL/minute)
    Unknown and in those with • Dosage can be
    moderate to severe reduced or stopped
    Half Life: hepatic impairment. without such rebound
    11-13 effects as platelet
    hours • Left ventricular outflow hyperaggregation.
    tract obstruction has
    been reported in • If aspirin is added
    patients with sigmoid- to drug therapy,
    shaped interventricular monitor patient for
    septum. aspirin-related
    adverse reactions.
    Dialyzable drug: No.

    Overdose S&S: Severe


    headache, diarrhea,
    hypotension,
    tachycardia, cardiac
    arrhythmias.
    ADMINISTRATION: Interactions:
    PO Drug-drug. Anticoagulants, antiplatelet agents: May
    increase bleeding risk. Use together cautiously.
    • Give drug at least 30 minutes before or 2 hours after
    breakfast and dinner. Fluconazole, omeprazole, ticlopidine: May increase
    cilostazol level. Reduce cilostazol dosage to 50 mg b.i.d.
    • Don’t give with grapefruit juice.
    Erythromycin, mifepristone, other macrolides, strong or
    moderate CYP3A4 inhibitors (diltiazem, itraconazole,
    ketoconezole): May increase level of cilostazol and its
    metabolites. Reduce cilostazol dosage to 50 mg b.i.d.

    Drug-herb. Herbs with anticoagulant properties (alfalfa,


    anise, bilberry): May prolong bleeding time. Discourage
    use together. Drug-lifestyle. Smoking: May decrease drug
    exposure. Discourage smoking.

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