 Permanent - The indefinite deferral would no longer apply if

- Ex. With HIV. prospective donor states that regulatory requirements changed and the donor
he/she has hepatitis B. qualified for re-entry based on results of improved
- Prospective donor is deferred from donation with no testing methods or a change in the impact of the
possibility for reentry. Some permanent deferrals may relevant transfusion transmitted infection, also referred
result from the testing performed on a previous to as RTTI.
donation - Indefinitely deferred donors may be eligible to donate
- Permanently deferred donors may be autologous blood.
eligible to donate autologous blood.
 Temporary Common question
- Ex. With fever. Donor has received a blood 1. General Health
transfusion; defer for 12 months from date Cold/flu symptoms,
of transfusion. headache, nauseous 2-3 weeks deferral
- Prospective donor is deferred from donation for a 2. Heart and lung disease
specified period of time. 3. Bleeding problems
- Temporarily deferred donors may be eligible to 4. Cancer – permanent deferral.
donate autologous blood. Leukemia and lymphoma = permanent deferral; First
 Indefinite basal/squamous cell carcinoma,
- Donor cannot donate, FDA don’t know when the Carcinoma in situ of the cervix,
donor is allowed to donate. surgically removed capillary
- Prospective donor is unable to donate blood for thyroid carcinoma = no deferral.
someone else for an unspecified period of time due to 5. Pregnancy – international = 3
current regulatory requirements that may change in the months after delivery deferral; Philippines = 9 months
future. after delivery deferral

Malaria (Plasmodium spp) -History of malaria: 3 years after treatment.

Endemic countries: -Lived in endemic country (5 consecutive years): 3 years
Philippines (Palawan, Cagayan, Negros, from departure
Occidental/Oriental) -Travel to endemic area: 1 year from departure.
 Africa -Malaria (without the specifics): 3 years after treatment.
Babesiosis (Babesia microti) -History of Babesiosis: indefinite
Endemic:
 North-Eastern United States Agent: Deer ticks (Ixodes scapularis)
Chaga’s disease (Tripanosoma cruzi -History of Chaga’s: indefinite
vector: kissing bug, etc.)
- America’s Tripanosomiasis Key indicator: Latin-American Immigrants.
Endemic:
 South and Central America
 Mexico
Lesihmaniasis -Travel to Iraq: 1 year after departure
Endemic
 Middle cost Causative agent: Sandfly (Phlebotomus species)
 Asia Key: 1990-1993 “operation desert storm” – war
 Mediterranean
 Africa
 South and Central America
MAMA ko nasa SC
Variant Creutzfeldt-Jakob disease Indefinite by geographic regions:
(vCJD) Risk: - Lived ≥ 3 months in UK from 1980-1996
1. Transplantation of human dura matter grafts -Lived ≥ 5 years in Europe (1980-present)
2. Corneal transplantation -Received blood transfusion in UK or France (1980-
3. Infection of human-derived growth hormone present)
4. Hereditary
Note:
-This is cumulative
-They may donate “source plasma”
Creutzfeldt-Jakob disease Indefinite
Endemic: - Blood relative of someone diagnosed with CJD or
 UK vCJD.
 France - Received bovine insulin since 1980
 Europe Permanent deferral is indicated for:
- Diagnosed with CJD or vCJD
- Donor received a dura mater transplant or pituitary
growth hormone from a human cadaver
- Risk: injection of human-derived growth hormone

Hepatitis Permanent:
- Positive test for hepatitis B surface antigen
Temporary:
-Diagnosed with viral hepatitis before age 11
Indefinite:
- Donor reacted positively for anti-HBc on more
than one occasion,
-Positive HBV NAT
12-month deferral:
- Sexual contact or living with a person (close contact)
 who has acute or chronic hepatitis B (test positive
for HBsAg or HBV)
-Who has symptomatic hepatitis C or other hepatitis
virus.

MEDICATION DEFERRALS
Medication Primary Use Deferral Comments
Finasteride (Proscar) Treat benign 1 month They are teratogenic – destroy
prostatic embryo that covers the fetus
hyperplasia
Finasteride (Propecia) Treatment of 1 month
male baldness or
alopecia
Isotretinoin (Accutane, Treat severe 1 month
Amnesteem, Claravis, acne
Sotret)
Dutasteride (Avodart, Treat benign 6 months
Jalyn) prostatic
hyperplasia
Acitretin (soriatane) Treat severe 3 years
psoriasis
Etretinate (Tegison) Treat severe Indefinite to
psoriasis permanent
Warfarin (Coumadin) Prevent blood 1 week Anticoagulants or “blood thinners” (usually to
clots prevent blood clots in the legs and lungs and to
prevent strokes)
Affect the blood’s ability to clot,which might
cause excessive bruising or bleeding when you
donate.
You may still be able to donate whole blood or
red blood cells by apheresis
Bovine insulin Treats diabetes indefinite Can cause madcow disease

Aspirin and piroxicam Aspirin: Anti International Anti-platelet agents (usually taken to prevent
(Feldene) pyretic : stroke or heart attack)
Piroxicam: Treat 36-48 hours Not be a suitable donor for platelet apheresis as
mild arthritis Philippines: these medications inhibit platelet function.
72
hours No restriction for whole blood donation

Clopidogrel (Plavix) Prevent blood clot 2 weeks

Ticlopidine (Ticlid)
Hepatitis B immune Exposure to 1 year If recombinant heap B immune globulin – no
globulin hepatitis (esp. deferral
hepatitis B)
Experimental meds or 1 year
unlicensed
(experimental) vaccines

Medication deferrals due to the nature of the disease Medications commonly accepted for blood donation
process for which these medicines are being 1. Hypnotics used at bedtime
used: 2. Blood pressure medications (if patient is free of side
1. Antibiotics effects and cardiovascular symptoms)
2. Anticonvulsants 3. Over the counter bronchodilators – most over the
3. Anticoagulants counter are not deferred
4. Insulin 4. Decongestants
5. Anti-arrythmic drugs 5. Oral contraceptives
6. Replacement hormones
7. Weight-reduction drugs
8. Mild analgesics
9. Vitamins – Vitamin C for immunity
10.Tetracyclines and other antibiotics taken for acne

VACCINATION/IMMUNIZATION DEFERRALS
NO DEFERRAL 2 WEEKS DEFERRAL 4 WEEKS DEFERRAL 12 MONTHS DEFERRAL
Killed vaccine MOMO SAY 2 weeks
1. Anthrax 1. Measles (rubeola) 1. German rubella
2. Cholera 2. Mumps measles / 2. Chicken pox
3. Diphtheria 3. Oral polio (sabin) rubella 1. Rabies post
4. Hepatitis B 4. Oral typhoid 2. Chicken pox exposure
vaccine 5. Smallpox (14-21 2. Hepatitis
Heptavax days after scab falls B
28 days if not off) immunoglobulin
recombinant - Close contact are 3. Rh
5. Hepatitis A also deferred immunoglobulin
6. Influenza (exposed to the 4. Gamma globulin
7. Lyme disease vaccination site/
8. Parathyphoid bandages/
9. Pertussis clothing/ towels/
10.Plague bedding)
11.Pneumococcal - Russia, CDC
polysaccharide atlanta
12.Polio (injection) - 6. Yellow fever
salk 7. Animal serum
13.Rabies (for products
prophylactic MMR: 8 weeks after
reasons) vaccination (DOH)
14.RMSF
15.Tetanus
16.Typhoid
17.Typhus

TEMPORARY DEFERRAL

- International Standard (after delivery)

6 weeks - Local Standard (9 mos)
-Conclusion of pregnancy

-Mucus membrane or skin penetration (exposure to blood)

12 months 1. Tattoos or permanent makeup (makes applied by a state-regulated facility with
sterile needles and ink that is not used)
o Can be allowed if the tattoo artist is licensed
2. Ear and body piercings
3. Acupuncture
4. Needle stick injuries
-Incarceration in a correctional (juvenile, lockup, prison, mental) institution for >72
hours – because of the practices (ex. Drugs, male-to-male intercourse)
-Completion of therapy for syphilis or gonorrhea (associated with HIV transmission)
-Transfusion of blood, component, human tissue, plasma derived clotting factor
concentrates
-Blood transfusion
1. Organ,tissue, BM transplantation
2. Bone or skin graft
-Human diploid cell-rabies vaccine after animal bite
-Sexual contact with anyone who: Is at high risk with anyone who:
1. A commercial sex worker (anyone who takes money or drugs or other payment
for sex) prostitute
2. Has used a needle to take steroid or any drugs not prescribed by physician
3. A hemophiliac or has taken clotting factor concentrate for a bleeding problem
4. Has HIV/AIDS or has had a positive test for HIV
5. For female donors: Sexual contact with a male who has ever had sexual contact
with another male since 1977 (1980s – HIV discovery)
-Has hepatitis (or lived with a person who has hepatitis) – “Inapparent transmission”
- “Living with” –same dwelling (house, apartment, dormitory) “Inapparent transmission”
- Start the deferral following discontinuation of the “close contact”
-Had sex with anyone who was born or lived in Camerron, Central African Republic,
Chad, Congo,and Nigera
-Donors who have recently undergone surgery where blood components were
transfused during surgery
Permanent Deferral -Viral hepatitis after 11th birthday (HCV, HBV,HDV) – because an individual becomes
sexually knowledgeable
- Positive test for Hepatitis B surface Ag (acute phase)
-Repeat reactive test for anti-HBc on more than 1 occasion
-Clinical or laboratory evidence of HCV,HTLV,or HIV infection by current FDA regulations
- Previous donation associated with Hepatitis, HIV,or HTLV transmission
-Behavioral risk factors for HIV infection according to current FDA guideline
-Xenotransplantation: Donor received cells, tissues, or organs from a nonhuman animal
source. Note: Nonliving biologics or materials from animals such as porcine heart valves
and porcine insulin are acceptable
Indefinite Deferral -History of cancer, leukemia, or lymphoma
o No deferral: Basal or squamous cell cancer, carcinoma in situ of the cervix,
and papillary thyroid carcinoma
- Hemophilia, von Willebrand disease, sickle cell anemia, thalassemia, Kaposi’s
sarcoma, polycythemia, or a history of receiving clotting factor concentrates
-Sex with a person who was born in any of the African countries
NOTE: CHILD DELIVERY
- Autologous collection- No deferral
-Transfusion (allogeneic blood) during pregnancy- within 12 months
o 1st and 2nd trimester abortion or miscarriage - No deferral
-Menstruation
o Hb= ≥13.5 g/dL and 1st time donor- No deferral
o Hb= < 13.5 g/dL- 1 week deferral
-Sexual contact with individual with permanent deferral 12 months
 e.g. Women who have had sexual contact with a man who has had sex with another
man
- Severe acute respiratory syndrome
-Travel to the following places:
o Toronto, Canada
o Hanoi, Vietnam
o Guanghong, China
o Singapore
-Did not contact infection 14 days
-Donor has been infected 1 month/28 days after contact
o West Nile Virus
- Travel or living in North America
- Diagnosed and treated 14 days after recovery
-Diagnosed and treated 28 days after the onset of illness
ADDITIONAL -Vaccination that are prepared from toxoids or killed organisms do not require deferral
INFORMATION if the donor is free of symptoms.
o Febrile episode – 2-3 weeks deferral
-Recombinant vaccines – No deferral
- Skin leasions:
1. Multiple needle marks – DOH: permanent deferral; harmening: indefinite
2. Rash due to poison ivy – none as long as the rash is not found in the target site
of puncture
-Vaccination that are prepared from toxoids or killed organisms do not require deferral
if the donor is free of symptoms. o Febrile episode – 2-3 weeks deferral
-History of cancer, leukemia, or lymphoma – permanent deferral except:
1. Basal or squamous cell carcinoma
2. Carcinoma in situ of the cervix
3. Surgically removed capillary thyroid carcinoma
-Active TB: Harmening: deferred for 2 years; DOH: 6-12 months deferral to two negative
exam results
-Alcohol intoxication – 12 hours after intake deferral deferred because they are
uncooperative
-Nigerian (or had sexual contact with Nigerian – Harmening: Permanent deferral
- Malaria (without the specifics) - 3 years deferral
-Dental surgery (dental extraction/ tooth extraction) – 1 year deferral after procedure
-Child delivery