Word Project
Word Project
Word Project
SUBMITTED TO
THE TAMILNADU DR. M.G.R. MEDICAL UNIVERSITY,
CHENNAI,
AS PARTIAL FULFILLMENT OF THE
BACHELOR OF PHYSIOTHERAPY DEGREE.
NOVEMBER 2023
CERTIFICATE
Date:
A PROJECT WORK ON
Guide: ……………………………………
PROFESSOR DR. A. AYYAPPAN MPT.,
Principal,
Excel College of Physiotherapy,
Komarapalayam, Namakkal –637303.
SUBMITTED TO
THE TAMILNADU DR. M.G.R. MEDICAL UNIVERSITY,
CHENNAI,
AS PARTIAL FULFILLMENT OF THE
BACHELOR OF PHYSIOTHERAPY DEGREE.
NOVEMBER 2023
A PROJECT WORK ON
NOVEMBER 2023
Last not the least, THANK YOU everyone who is part of this
academic journey of my life.
CONTENTS
S. NO TITLE PAGE NO
ABSTRACT
INTRODUCTION
1.1 BACKGROUND
1.2 CLASSIFICATION
1 1.3 EPIDEMIOLOGY
1.4 VIRTUAL REALITY
1.5 OPERATIONAL DEFINITION
2 REVIEW OF LITRATURE
AIMS AND OBJECTIVES
3.1 AIMS
3 3.2 OBJECTIVES
3.3 STATEMENT OF THE PROBLEM
MATERIALS AND METHODOLOGY
4.1 MATERIALS
4.2 METHODOLOGY
4.3 SAMPLING TECHNIQUE
4.4 SAMPLING SIZE
4.5 STUDY SETTING
4.6 STUDY DURATION
4.7 STUDY CRITERIA
4 4.8 HYPOTHESIS
4.9 OUTCOME MEASURES
4.10 VARIABLES
DEPENDENT
INDEPENDENT
4.11 TREATMENT TECHNIQUE
4.11.1 VIRTUAL REALITY
411.2 CONVENTIONAL TRAINING
5 STATASTICAL TOOLS
6 DATA PRESENTATION
7 DATA ANALYSIS AND GRAPHICAL
PRESENTATIONS
8 RESULTS AND DISSCUSSIONS
9 SUMMARY AND CONCLUSION
10 LIMITATION AND RECOMMENDATION
11 BIBLIOGRAPHY
12 REFERENCE
13 APPENDIX
PARAMETER
14 14.1 FUNCTIONAL INDEPENDENCE MEASURE
14.2 MODIFIED BARTHEL INDEX
CASE STUDY 1
15 CASE STUDY 2
CASE STUDY 3
ABSTRACT
Background: In recent years, efforts have been made to implement virtual reality
(VR) to support the delivery of poststroke upper extremity motor rehabilitation
exercises. Therefore, it is important to review and analyze the existing research
evidence of its effectiveness.
Results: A total of 50 trials were analyzed. Compared with the control groups that
used either conventional therapy or no therapy, the intervention groups that used VR
to support exercise therapy showed significant improvements in upper extremity
motor function.
1.1 BACKGROUND
DISABILITY
It is defined as the “Functional loss due to permanent physical impairment
resulting from congenital condition, disease or trauma”. It excluded illness/injury of
recent origin (morbidity) resulting into temporary loss of ability to see, hear, speak or
move
Disability results from the interaction between individuals with a health condition,
such as cerebral palsy, Down syndrome and depression, with personal and
environmental factors including negative attitudes, inaccessible transportation and
public buildings, and limited social support.
A person’s environment has a huge effect on the experience and extent of disability.
Inaccessible environments create barriers that often hinder the full and effective
participation of persons with disabilities in society on an equal basis with others.
Progress on improving social participation can be made by addressing these barriers
and facilitating persons with disabilities in their day to day lives.
1
TYPES OF DISABILITIES :
PRIMARY DISABILITIES :
SECONDARY DISABILITIES:
Secondary disabilities are disabilities that the individual is not born with. These
disabilities and behaviours develop over time because of a poor fit between the person
and the environment.secondary disability means a disability that is, or results from,
the aggravation, acceleration, exacerbation, deterioration or recurrence of a prior
disability
Disabilities that did not exist at the onset of primary disability but develop
subsequently are called secondary disability. E.g. Joint contractures in poliomyelitis.
Disability has been described as significantly restricted ability, relative to an
individual or group norm and this term is often used to refer to individual functioning
including physical or sensory impairment, cognitive impairment or mental disorder
3
STROKE:
The 24-hour limit divides stroke from transient ischemic attack, which is a
related syndrome of stroke symptoms that resolve completely within 24 hours With
the availability of treatments that can reduce stroke severity when given early, many
now prefer alternative terminology, such as "brain attack" and "acute ischemic
cerebrovascular syndrome" (modelled after heart attack and acute coronary syndrome,
respectively), to reflect the urgency of stroke symptoms and the need to act swiftly.
A stroke is a medical condition in which poor blood flow to the brain causes
cell death. There are two main types of stroke
Signs and symptoms of a stroke may include an inability to move or feel on one
side of the body, problems with understanding or speaking, dizziness, or loss of vision
to one side .Signs and symptoms often appear soon after the stroke has occurred.
If symptoms last less than one or two hours, the stroke is a transient ischemic
attack (TIA), also called a mini-stroke. A hemorrhagic stroke may also be associated
with a severe headache . The symptoms of a stroke can be permanent.Long-term
complications may include pneumonia and loss of bladder control
The United States has an estimated 3 million stroke survivors today, which is
double the number of survivors 25 years ago. The economic impact of stroke in 2007
was estimated at $62.7 billion, markedly increased from the estimate in 2001 of $30
billion, of which $17 billion were direct medical costs and $13 billion were indirect
costs from lost productivity. Fortunately, modern medical interventions (mostly risk
factor modifications) have decreased stroke mortality rates by approximately 7% per
year in industrialised nations since 1970. The advances continue but with increased
cost of care for more advanced treatments.
4
The biggest risk for stroke is high blood pressure. Other risk factors include high
blood cholesterol , tobacco, smoking , obesity, diabetes mellitus, a previous TIA, end
stage kidney disease and atrial fibrillation . An ischemic stroke is typically caused by
blockage of a blood vessel, though there are also less common causes. A hemorrhagic
stroke is caused by either bleeding directly into the brain or into the space between
the brains membranes Bleeding may occur due to a ruptured brain aneurysm
Diagnosis is typically based on a physical team and supported by medical imaging
such as a CT scan or MRI scan.
A CT scan can rule out bleeding, but may not necessarily rule out ischemia,
which early on typically does not show up on a CT scan.Other tests such as an
electrocardiogram (ECG) and blood tests are done to determine risk factors and rule
out other possible causes. Low blood sugar may cause similar symptoms.
Prevention includes decreasing risk factors, surgery to open up the arteries to the
brain in those with problematic carotid narrowing , and warfarin in people with atrial
fibrillation . Aspirin or stains may be recommended by physicians for prevention.
5
1.2CLASSIFICATION :
1. Ischemic
2. Hemorrhagic
Ischemic strokes are caused by interruption of blood supply to the brain, while
hemorrhagic strokes result from the rupture of a blood vessel or an abnormal vascular
structure. About 87% of strokes are ischemic, the rest being hemorrhagic. Bleeding
can develop inside areas of ischemia, a condition known as “hemorrhagic
transformation" It is unknown how many hemorrhagic strokes actually start as
ischemic strokes.
Ischemic:
In an ischemic stroke, blood supply to part of the brain is decreased, leading to
dysfunction of the brain tissue in that area. There are four reasons why this might
happen:
6
A stroke without an obvious explanation is termed a cryptogenic stroke
(idiopathic) ; this constitutes 30–40% of all ischemic strokes.
There are various classification systems for acute ischemic stroke. The Oxford
Community Stroke Project classification (OCSP, also known as the Bamford or
Oxford classification) relies primarily on the initial symptoms; based on the extent of
the symptoms, the stroke episode is classified as total anterior circulation infarct
(TACI), partial anterior circulation infarct (PACI), lacunar infarct (LACI) or
posterior circulation infarct (POCI). These four entities predict the extent of the stroke,
the area of the brain that is affected, the underlying cause, and the prognosis.The
TOAST (Trial of org 10172 in Acute Stroke Treatment) classification is based on
clinical symptoms as well as results of further investigations; on this basis, a stroke is
classified as being due to : thrombosis or embolism due to atherosclerosis of a large
artery, an embolism originating in the heart, complete blockage of a small blood
vessel, other determined cause, undetermined cause
7
HEMORRHAGIC:
The above two main types of hemorrhagic stroke are also two different forms of
intracranial haemorrhage , which is the accumulation of blood anywhere within the
cranial vault but the other forms of intracranial haemorrhage, such as epidural
hematoma (bleeding between the skull and the dura mater, which is the thick
outermost layer of the meninges that surround the brain) and subdural hematoma
(bleeding in the subdural space), are not considered "hemorrhagic
strokes".Hemorrhagic strokes may occur on the background of alterations to the blood
vessels in the brain, such as cerebral amyloid angiopathy , cerebral arteriovenous
malformation and an intracranial aneurysm, which can cause intraparenchymal or
subarachnoid haemorrhage.
8
1.3EPIDEMIOLOGY:
The epidemiology of “all strokes'' lumped together is one matter, whereas the
epidemiology of the various stroke types and subtypes may be quite another. Ideally,
all require study. But, until the quiet recent past, most epidemiological studies and
clinical trials were based mainly on all strokes, sometimes with separate analysis of
the rather distinct clinical syndrome of spontaneous subarachnoid haemorrhage.
Stroke is a major global public health problem . According to the global burden
of diseases (GBD) study in 1990, stroke was the second leading cause of death
worldwide . subsequent efforts to update the GBD study reported nearly 5.87 million
stroke deaths globally in 2010, as compared to 4.66 million in 1990.
This indicated a 26 percent increase in global stroke deaths during the past two
decades . With the rising proportion of mortality, stroke still remains the second
leading cause of death worldwide .
According to the estimates from the GBD study in 2001, over 85% of the global
burden of stroke was borne by low-and middle-income countries. Given the lack of
reliable reporting mechanisms and disease or death registration system in LMICs , the
epidemiological findings from the GBD study for most of the LMICs, are likely to be
underestimated .
9
A global systematic review of population-based stroke studies has documented
that the incidence rate of stroke in LMICs has increased from
56/100,000 person-years during 1970-1979 to 117/100,000 person-years during
the period 2000-2008. This study has also reported a decrease in the stroke incidence
from 163 per 100,000 person-years in 1970-1979 to 94 per 100,000 person-years
during 2000-2008 in high-income countries (HICs) indicating approximately 42 per
cent decrease in stroke incidence in HICs and more than double increase in stroke
incidence in LMICs, during the past four decades.
Most of these studies are cross-sectional, and the primary objectives of these
studies are also diverse. Given the paucity of data and lack of reliable reporting
mechanisms, understanding the epidemiology of stroke in India is challenging.
Hence, we conducted a systematic review of epidemiological studies of stroke in
India with an objective to investigate the incidence and prevalence of stroke in India
and understand the true magnitude of the problem.
The United States has an estimated 3 million stroke survivors today, which is
double the number of survivors 25 years ago. The economic impact of stroke in 2007
was estimated at $62.7 billion, markedly increased from the estimate in 2001 of $30
billion, of which $17 billion were direct medical costs and $13 billion were indirect
costs from lost productivity. Fortunately, modern medical interventions (mostly risk
factor modifications) have decreased stroke mortality rates by approximately 7% per
year in industrialised nations since 1970. The advances continue but with increased
cost of care for more advanced treatments.
The syndromes that lead to stroke comprise two broad categories: ischemic and
hemorrhagic stroke. Ischemic strokes account for approximately 80% of strokes, and
hemorrhagic strokes account for the remaining 20%.
11
MORTALITY BY AGE AND SEX:
In a study conducted by khaw , the study illustrated a table showing the mortality
rates for stroke by age and sex in the United kingdom. Rates rise sharply with
increasing age. In marked contrast with coronary heart disease , in which there is a 5:1
male: female ratio at younger ages , there is a consistent sex differential in stroke
mortality rates
Age-specific stroke: The incidence of stroke increases with age, doubling after
the age of 55 years. However, in an alarming trend, strokes in people aged 20–
12
54 years increased from 12.9% to 18.6% of all cases globally between 1990
and 2016. Nevertheless, age-standardised attributable death rates decreased by
36.2% over the same period
PATHOPHYSIOLOGY :
Ischemic stroke: Ischemic stroke is caused by deficient blood and oxygen supply
to the brain; hemorrhagic stroke is caused by bleeding or leaky blood
vessels.Ischemic occlusions contribute to around 85% of casualties in stroke patients,
with the remainder due to intracerebral bleeding. Ischemic occlusion generates
thrombotic and embolic conditions in the brain. In thrombosis, the blood flow is
affected by narrowing of vessels due to atherosclerosis. The build-up of plaque will
eventually constrict the vascular chamber and form clots, causing thrombotic stroke.
In an embolic stroke, decreased blood flow to the brain region causes an embolism;
the blood flow to the brain reduces, causing severe stress and untimely cell death
(necrosis). Necrosis is followed by disruption of the plasma membrane, organelle
swelling and leaking of cellular contents into extracellular space , and loss of neuronal
function. Other key events contributing to stroke pathology are inflammation, energy
failure, loss of homeostasis, acidosis, increased intracellular calcium levels,
excitotoxicity, free radical-mediated toxicity, cytokine-mediated cytotoxicity,
complement activation, impairment of the blood–brain barrier, activation of glial cells,
oxidative stress and infiltration of leukocytes
➢ Communication deficits
➢ Decreased sensory awareness
➢ Perceptual deficits
➢ Tonal alteration
➢ Muscle weakness
➢ Abnormal synergies
➢ Tightness
➢ Imbalance
➢ Incoordination
15
EARLY WARNING SIGNS OF STROKE INCLUDE :
Face drooping
Arm weakness & Temporary loss of basic muscle movement
Speech difficulty & dysarthria
Head ache & Dizziness
Sudden confusion
Aphasia
16
MANAGEMENT :
Physiotherapy management
The past decade has seen an exponential growth in the number of randomised
control trials (RCT) in relation to physiotherapy interventions utilised in Stroke.
Veerbeek et al (2014) highlight that the number of RCTs on "Stroke Interventions"
has almost quadrupled in the past 10 years, with strong evidence seen in 30 out of 53
interventions for beneficial effects on one or more outcomes. The main changes lie in
the increased number of interventions to which ‘strong evidence’ could be assigned
and an increase in the number of outcomes for which the findings are statistically
significant.
18
Splinting
STROKE
"Rapidly developed clinical signs of focal or global disturbance of cerebral
function, lasting more than 24 hours or leading to death with no apparent cause other
than of vascular origin". 1970-WHO
20
HEMIPLEGIA
"a paralysis of one side of the body is the classic sign of neuro vascular disease
of the brain It is one of the manifestation of neuromuscular disease and it occurs with
stroke involving cerebral hemisphere or brain or brainstem".
VIRTUAL REALITY
computer-based technology that allows users to interact with a multisensory
simulated environment and receive ‘real-time’ feedback on performance”. The
interactive games are designed to provide the patient with real-life scenarios and
activities relevant to daily living.
CONVENTIONAL TRAINING
Conventional physiotherapy is defined as the treatment of movement disorders caused
by impairments of joints and the muscles that move the joints. It is a health care
profession concerned with human function and movement and maximizing physical
potential. The three main components of conventional physiotherapy are mobilization,
strengthening, and stretching. Depending on the supposed origin of the disorder, the
physiotherapist will opt for the corresponding treatment approach
FUNCTIONAL ACTIVITIES
Activities of daily living (ADLs or ADL) is a term used in healthcare to refer to
people's daily self-care activities
21
with other disabling conditions. It measures what patients do in practice. Assessment
is made by anyone who knows the patient well.
22
CHAPTER 2
REVIEW OF LITERATURE
The other outcomes tested were not statistically significant based on the results of this
review. As this topic remains relatively novel in the realm of stroke rehabilitation,
current research concludes that future investigations will be required to provide
higher-quality evidence to identify the effects of VR interventions on various
components of stroke rehabilitation.
23
3. More recently, A Case Series by Irene Cortés-Pérez et al (2020) "Immersive
Virtual Reality in Stroke Patients as a New Approach for Reducing Postural
Disabilities and Falls Risk", in this study, Three chronic ischemic stroke patients were
selected. One patient who received 25 sessions of immersive VR intervention for two
months was compared with another patient who received equivalent CT and a third
patient with no intervention. Balance, gait, risk of falling, and vestibular and visual
implications in the equilibrium were assessed. After the interventions, the two patients
receiving any of the treatments showed an improvement in balance compared to the
untreated patient. In comparison to CT, our results suggest a higher effect of
immersive VR in the improvement of balance and a reduction of falls risk due to the
active upright work during the VR intervention.The research shows positive outcomes
in improving upper limb function with the use of standard physiotherapy and Virtual
Games (VR) as compared to receiving only standard physiotherapy among stroke
survivors.
4. S. Viñas-Diz a, M. Sobrido-Prieto et al ., 2016
Strong scientific evidence supports the beneficial effects of VR on upper limb motor
recovery in stroke patients. Further studies are needed to fully determine which
changes are generated in cortical reorganisation, what type of VR system is the most
appropriate, whether benefits are maintained in the long term, and which frequencies
and intensities of treatment are the most suitable.
5. Owen O’Neil MRes, BSc a, Manuel Murie Fernandez MD, PhD b, Jürgen
Herzog MD c, Marta Beorchia MSc d, Valerio Gower MSc e, Furio Gramatica
MSc f, Klaus Starrost MSc g, Lorenz Kiwull MD 2018
This narrative article offers insights to clinicians with an interest in how VR can be
used for motor rehabilitation in a clinical context. The settings described include 3
different service delivery models for methods of integrating VR for motor impairment
in neurologic rehabilitation.
These settings included an inpatient application for Parkinson disease, a Kiosk model
for pediatrics, and a telerehabilitation approach for home rehabilitation. Overall, the
clinics found good responses from
24
6. Erika Pedreira da Fonseca PT, MSc * †, Nildo Manoel Ribeiro da Silva PT,
PhD ‡, Elen Beatriz Pinto PT, PhD 2017
The results of this study showed that after a stroke, patients undergoing treatment that
included virtual reality and patients receiving conventional therapy showed an
improvement in balance during gait and a reduction in the occurrence of falls. The
differences in gait balance after intervention in the control group and the reduction in
the occurrence of falls in the treatment group were significant. However, the
intergroup analysis showed no difference between the two outcomes.
7. Jiayin Chen ; Calvin Kalun ; Tianrong Chen 2022
Our findings contribute further evidence to the literature, showing that VR-supported
exercise therapy is effective in improving motor function, especially gross motor
function. One possible explanation for our findings is that VR promotes motor
learning. First, VR can promote access to therapeutic exercises; it can be used to
simulate real-life environments, which allows for real-time interactions and provides a
means for individuals to practice therapeutic tasks that may not be feasible to perform
in the real world because of resource limitations or safety concerns Second, virtual
environments can provide visual, auditory, or haptic feedback that can facilitate motor
skill learning.
8. Steven Truijen et al. Neurol Sci. 2022
In the last decade, there is a growing interest in the use of virtual reality for
rehabilitation in clinical and home settings. The aim of this systematic review is to do
a summary of the current evidence on the effect of home-based virtual reality training
and telerehabilitation on postural balance in individuals with central neurological
disorders.
9. Christine Glenny & Paul Stolee
The purpose of this review was to accumulate and synthesize past research focusing
on the reliability and validity of the FIM and the MDS for use with older adults. To
our knowledge, there have been no publications to date that have systematically
reviewed and compared evidence of the psychometric properties of both tools. It is
important for functional status outcome measures to be validated for use with older
adults because this group of individuals represents a substantial proportion of the
25
population being assessed with these instruments. Also, it is unlikely that the
measurement properties of assessment tools will be consistent between the older and
younger populations
26
12. Yuto Kameyama et al. J Stroke Cerebrovasc Dis. 2022
There is no unified view of the relationship between sarcopenia and the activities of
daily living (ADL) in stroke patients. This study aimed to determine whether
sarcopenia affects the ADL in elderly patients with stroke.
27
28
CHAPTER 3
AIMS AND OBJECTIVES
29
CHAPTER 4
4.1 MATERIALS
Couch
Xbox
Display screen
Jockey
Pillows
Mirror box
Stool
Weighing machine
Inch tape.
Chair
Table
blanket
Plastic cups - 2
Peg board
Books
Sponge balls
Towel
Drawer
200g jar of coffee
push-button telephone
pencil
2.3L plastic pitcher with lid
250 ml plastic cup
wash cloth
wash basin (24.5 cm. in diameter, height 8 cm.)
30
Pull-on vest with 5 buttons
bath towel (65cm X 100cm)
75ml toothpaste with screw lid, >50% full
Toothbrush
dinner plate (Melamine or heavy plastic, 25 cm. in diameter)
medium resistance putty
knife and fork & Handkerchief
built up handles the length of the utensil handle
Metal zipper in polar fleece poncho
Container (50 x 37 × 27em)
A plastic grocery bag holding 2kg weight
Reflex hammer & Swiss ball
6 Months
31
4.7. TREATMENT DURATION
45 minutes per session, 2 session per day, 6 days per week, total duration of
treatment about 24 weeks.
INCLUSION
EXCLUSION
32
4.9. HYPOTHESIS
FIM scale
Modified barthel index scale
4.11. VARIABLES
Virtual reality
Conventional training
33
4.12 TREATMENT TECHNIQUES
PROCEDURE
The selected patients received clear explanation about the treatment procedure
prior to the study.
The written informed consent form was received before the intervention begun.
The participants received interventions with a target of 6 training sessions per
week for 6 months of up to 45 minutes duration and 2 sessions per day .
The pre and post test values were taken by using Functional independence
measure and Modified Barthel index
Designated research therapists provided both the VR training and the CT as an
addition to standard rehabilitation. The amount of physical therapy provided was
registered for each patient.
Informing the patients :
Before the first session, the patients were sufficiently instructed about the
background and aims of Virtual reality and about conventional training respectively,
as well as the respective side effects of the treatment and they were made aware of the
importance of continuous, frequent training and self management.
GROUP A:
Patients from group A (experimental group) received VR training with the
YouGrabber system. It consists of sensors attached to the ceiling, an infrared camera,
and software in combination with a television developed for rehabilitation purposes. It
comprises several games that the therapist can adapt to the patient's actual motor
abilities. The different therapy modes include reaching and grasping exercises,
selective finger movements, supination/pronation, whole-arm movements, unimanual
or bimanual training, and virtually enhanced movements, i.e., movements that can be
visually increased on the screen. Game parameters that could be adjusted were
prioritized among others, speed of objects, intervals between objects, and dispersion
to the left and right of object positions.
34
GAMES ADMINISTERED :
Rowing game
Fruit crush
Wall painting
Fruit ninja
35
GROUP B:
Patients randomized to the control group participated in CT under supervision of a
therapist to match the therapy time provided in the experimental group. Conventional
arm training was based on a set of standardized exercises along with mirror box
therapy, task oriented approach and motor relearning program with an emphasis on
task-related practice. It included exercises for different gross movements and
dexterity using a variety of grips and selective finger movements.
Exercises such as :
36
37
CHAPTER 5
STATISTICAL TOOLS
∑ 2 −(̅)2
S=
−1
∑
̅=
̅
t=
S= standard deviation
38
CHAPTER 6
DATA PRESENTATION
FUNCTIONAL INDEPENDENCE MEASURE :MAX SCORE-126
(GROUP A : EXPERIMENTAL GROUP)
MEAN
PRE-TEST POST-TEST MEAN
Sr. No DIFFERENCE
VALUE VALUE DIFFRENCE
SQUARE
1 56 63 7 49
2 28 34 6 36
3 29 34 5 25
4 33 39 6 36
5 36 42 6 36
6 79 86 7 49
7 53 58 5 25
8 34 39 5 25
9 43 49 6 36
10 30 36 6 36
11 73 78 5 25
12 62 68 6 36
13 78 85 7 49
14 27 33 6 36
15 32 38 6 36
16 67 76 9 81
17 57 65 8 64
18 51 57 6 36
19 47 56 9 81
20 45 52 7 49
21 40 45 5 25
22 72 78 6 36
39
23 35 42 7 49
24 47 53 6 36
25 62 67 5 25
TOTAL VALUE 157 1017
GROUP B (CONTROL GROUP)
S.NO PRE-TEST POST-TEST MEAN MEAN
VALUES VALUES DIFFRENCE DIFFERENCE
SQUARE
1 73 75 2 4
2 62 65 3 9
3 78 81 3 9
4 27 30 3 9
5 32 35 3 9
6 67 71 4 16
7 57 60 3 9
8 51 54 3 9
9 47 49 2 4
10 45 50 5 25
11 56 60 4 16
12 28 32 4 16
13 29 31 2 4
14 33 36 3 9
15 36 39 3 9
16 79 81 2 4
17 53 57 4 16
18 34 37 3 9
19 43 48 5 25
20 27 30 3 9
21 32 35 3 9
22 67 71 4 16
23 57 60 3 9
24 51 54 3 9
40
25 30 34 4 16
TOTAL 81 279
MEAN
V Sr. POST-TEST MEAN
PRE-TEST VALUE DIFFERENCE
No VALUE DIFFRENCE
SQUARE
1 82 90 8 64
2 54 61 7 49
3 28 33 5 25
4 24 32 8 64
5 54 60 6 36
6 24 29 5 25
7 28 35 7 49
8 31 39 8 64
9 75 82 7 49
10 31 39 8 64
11 67 74 7 49
12 27 34 7 49
13 53 58 5 25
14 82 88 6 36
15 74 79 5 25
16 65 71 6 36
17 53 58 5 25
18 27 33 6 36
19 68 73 5 25
20 67 75 8 64
41
21 54 61 7 49
22 32 39 7 49
23 33 41 8 64
24 42 49 7 49
25 23 28 5 25
TOTAL VALUE 163 1095
42
21 56 60 4 16
22 36 38 2 4
23 41 45 4 16
24 63 65 2 4
25 32 35 3 9
TOTAL VALUE 82 310
CHAPTER 7
DATA ANALYSIS & INTERPRETETION
7.1 GROUP A (EXPERIMENTAL GROUP)
43
7.2 GROUP B (CONTROL GROUP)
44
45
CHAPTER 8
RESULTS AND DISSCUSSION
8.1 : Functional Independence Measure Scale
The calculated 't value for the experimental group is 27.86 whereas for the
control group the calculated ‘t value is 19.51 . Since the calculated value between
both the groups exhibits a clear difference that is the control group has less value
than the experimental group Hence, Null hypothesis is rejected and alternate
hypothesis accepted.
8.2 : Modified Barthel Index scale
The calculated 't value for the experimental group is 66 whereas for the control
group the calculated ‘t value is 12.59. Since the calculated value between both the
groups exhibits a clear difference that is the control group has less value than the
experimental group Hence, Null hypothesis is rejected and alternate hypothesis
accepted.
DISCUSSION
The aim of the study was to find the effectiveness of Virtual reality versus
conventional training among post stroke patients on improving upper limb functional
activities has been proved. Patient showed changes in their upper limb functions
considerably during the study period.
In this study, functional independence of the patient was measured by functional
independence measure and modified barthel index scale. This study showed that
"There was statistical significant difference in the post test mean and the pre test
mean."
The gamification of VR rehabilitation interventions is believed to motivate
patients to actively participate with pleasure thus increasing the tasks performed and
augmenting their recovery. When participants are more interested, they are more
concentrated and more persistent in completing their tasks. Certain benefits in
psychological outcomes should always be acknowledged as a positive component,
especially in neurological patients who often are faced with a long recovery
(Qian..et.al..2020). Our results are in agreement with those of previous systematic
reviews or narrative ones that have examined semi-immersive VR interventions (Yates
et al., 2016; Porras et al., 2018; Rutkowski et al., 2020) and with a scoping review that
assessed the application of HMD in adult physical rehabilitation (Saldana et al., 2020). The
authors did state that the use of HMD as a low-cost, portable tool seems to have additional
46
benefits, but the generalization of the findings is yet to be discussed due to the relatively low
level of evidence and the small number of participants (Saldana et al., 2020). Another key
aspect noted also by Porras et al. (2018) is the additional benefits of incorporating VR in
conventional rehabilitation, such as motivation and engagement.
47
CHAPTER 9
48
CHAPTER 10
10.1. LIMITATIONS:
As only small sample size is included in this study, the result
cannot be generalised
Patients with age 25-50 years were only taken for the study.
10.2. RECOMMENDATION
Other conditions such as cerebral palsy with lack of upperlimb
motor control also be treated by using virtual reality and
conventional training
The Study was carried out for a short duration, long term study is
recommended for further exploration.
49
50
CHAPTER 11
BIBLIOGRAPHY
51
CHAPTER 12
REFERENCE
1. Adams, R. J., Lichter, M. D., Ellington, A., White, M., Armstead, K., Patrie, J. T.,
et al. (2018). Virtual Activities of Daily Living for Recovery of Upper Extremity
Motor Function. IEEE Trans. Neural Syst. Rehabil. Eng. 26 (1), 252–260.
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59
CHAPTER 13
APPENDICES
The Researcher has briefed me in detail about the treatment approach as well as
explained the risks of participation and has answered the questions related to the
research to my satisfaction.
SIGNATURE OF PARTICIPANT:
SIGNATURE OF RESEARCHER:
SIGNATURE OF WITNESS:
60
APPENDIX - 2
ASSESSMENT CHART
Name:
Age/Sex :
RegNo:
D.O.Adm :
D.O.Ass:
Pathology :Isch/hem
Affected Side: R/L
Outcome Measures:
Group:
Duration of Treatment:
Intervention:
Date:
61
CHAPTER 14
PARAMETERS
MODIFIED BARTHEL INDEX
INDEX ITEM SCORE DESCRIPTION
0 Unable to participate in a transfer. Two attendants are required to transfer
the
patient with or without a mechanical device.
8 The transfer requires the assistance of one other person. Assistance may be
CHAIR/BED required in any aspect of the transfer.
TRANSFERS
12 The presence of another person is required either as a confidence measure, or
to
provide supervision for safety.
0 Dependent in ambulation.
1 Patient can propel self short distances on flat surface, but assistance is
required for
AMBULATION all other steps of wheelchair management.
/WHEELCHAI
R
62
3 Presence of one person is necessary and constant assistance is required to
manipulate chair to table, bed, etc.
* (If unable to
walk)
4 The patient can propel self for a reasonable duration over regularly
encountered
Only use this terrain. Minimal assistance may still be required in “tight corners” or to
item if the negotiate
patient is a kerb 100mm high.
rated “0” for
Ambulation,
and then
only if the 5 To propel wheelchair independently, the patient must be able to go around
patient has corners,
been trained turn around, manoeuvre the chair to a table, bed, toilet, etc. The patient must
in be
wheelchair able to push a chair at least 50 metres and negotiate a kerb.
management.
5 The patient is able to ascend/descend but is unable to carry walking aids and
needs
supervision and assistance.
STAIR
CLIMBING
8 Generally no assistance is required. At times supervision is required for
safety due
to morning stiffness, shortness of breath, etc.
10 The patient is able to go up and down a flight of stairs safely without help or
supervision. The patient is able to use hand rails, cane or crutches when
needed
and is able to carry these devices as he/she ascends or descends.
TOILET 8 Supervision may be required for safety with normal toilet. A commode may
TRANSFERS be
used at night but assistance is required for emptying and cleaning.
10 The patient is able to get on/off the toilet, fasten clothing and use toilet paper
without help. If necessary, the patient may use a bed pan or commode or
urinal at
night, but must be able to empty it and clean it.
63
2 The patient needs help to assume appropriate position, and with bowel
movement
facilitatory techniques.
5 The patient can assume appropriate position, but cannot use facilitatory
techniques
or clean self without assistance and has frequent accidents. Assistance is
required
BOWEL with incontinence aids such as pad, etc.
CONTROL
8 The patient may require supervision with the use of suppository or enema
and has
occasional accidents.
10 The patient can control bowels and has no accidents, can use suppository, or
take
an enema when necessary.
BLADDER 5 The patient is generally dry by day, but not at night and needs some
CONTROL assistance
with the devices.
8 The patient is generally dry by day and night, but may have an occasional
accident
or need minimal assistance with internal or external devices.
10 The patient is able to control bladder day and night, and/or is independent
with
internal or external devices.
The patient may use a bathtub, a shower, or take a complete sponge bath.
The
5 patient must be able to do all the steps of whichever method is employed
without
another person being present.
The patient can wash his/her hands and face, comb hair, clean teeth and
shave. A
5 male patient may use any kind of razor but must insert the blade, or plug in
the
razor without help, as well as retrieve it from the drawer or cabinet. A
female
patient must apply her own make-up, if used, but need not braid or style her
hair.
The patient can feed self from a tray or table when someone puts the food
within
reach. The patient must put on an assistive device if needed, cut food, and if
10 desired use salt and pepper, spread butter, etc.
SCORE INTERPRETATION
00 - 20 Total Dependence
21 - 60 Severe Dependence
61 - 90 Moderate Dependence
91 - 99 Slight Dependence
- 100 Independence
66
SCORE PREDICTION
Less Than 40 Unlikely to go home
● Dependent in Mobility
● Dependent in Self Care
Each item is scored on a 7 point ordinal scale, ranging from a score of 1 to a score of 7.
The higher the score, the more independent the patient is in performing the task
associated with that item.
FIM levels
No Helper
65
Helper - Modified Dependence
motor subscale (the sum of the individual motor subscale items) will be a value
between 13 and 91.
cognition subscale (the sum of the individual cognition subscale items) will be a
value between 5 and 35.
The total score for the FIM instrument (the sum of the motor and cognition subscale
scores) will be a value between 18 and 126.
66
CHAPTER 15
CASE STUDY 1
SUBJECTIVE:
NAME: Nandhini
AGE : 29
SEX : Female
OCCUPATION: Finance manager
DATE OF ASSESSMENT: 15/05/2023
CLINICAL DIAGNOSIS :Haemarrhagic stroke
HAND DOMINANCE: Right
CHIEF COMPLAINTS: Patient is unable to move her right hand and leg.
Also she felt some abnormality in her face while seeing the mirror.
HISTORY TAKING :
HISTORY OF PRESENT ILLNESS:
The onset of illness occured before a couple of years during her first labour.
On May of 2019 she give birth to baby girl under C section. And after 3 days she got an
episode of seizure at night during her dinner. Then she was taken to a near by hospital and
got some IV. Then they referred her to Senthil Neuro where she diagnosed with stroke as
MRI and CT was taken immediately .Then she underwent craniotomy and remained
unconscious for 10 days after which she prescribed drugs for 6 months then she continued her
treatment along with physiotherapy in Arogya rehabilitation.
DRUG HISTORY: For seizures and Hypertension
SURGICAL HISTORY: C section, uterus cyst removal, craniotomy
FAMILY HISTORY: No any relevant history of previous stroke in family
PAIN HISTORY: Shoulder, Sudden, aching
OBJECTIVE
ON OBSERVATION: Enters into Dept. with her mothers support
BODY BUILT: Monomorphic
FACIAL EXPRESSION :Grimacy
ATTITUDE OF LIMBS: Left upper limb Adducted and patient hold it by using contralateral
upper limb.
POSTURE: Faulty, shoulder drooped
67
ON EXAMINATION
SPECIAL SENSES
Vision- normal
Hearing- normal
Speech- slow and clumsy
PERCEPTION
Apraxia Intact
Figure ground perception Intact
Spatial orientation Intact
Left right discrimination intact
68
ELBOW
MOVEMENT RIGHT LEFT
Flexion
Normal 1+
Extension
WRIST
MOVEMENT RIGHT LEFT
Flexion
Normal 1+
Extension
HIP
MOVEMENT RIGHT LEFT
Flexion
Normal 1+
Extension
KNEE
MOVEMENT RIGHT LEFT
Flexion Normal 1
Extension Normal 1+
69
MUSCLE STRENGTH:
MOVEMENT RIGHT LEFT
Shoulder flexion Normal 4-
Shoulder extension 4-
Shoulder abduction 3+
Shoulder adduction 4-
Elbow flexion 3+
Elbow extension 3+
Supination 3+
Pronation 3+
Wrist flexion 2
Weist extension 2
Finger flexion 1
Finger extension 1
REFLEX INTEGRITY
Superficial: normal
Deep tendon: 4+
SENSORY FUNCTION
Intact (superficial & deep)
FUNCTIONAL MOBILITY
Barhel index:33
Functional independence measure :47
70
CASE STUDY 2
SUBJECTIVE
NAME: Mrs. Saraswathi
AGE: 57
SEX : F
OCCUPATION: House wife
DATE OF ASSESSMENT: 24/03/2023
CLINICAL DIAGNOSIS: Parkinsonism with depression
HAND DOMINANCE: Right
CHIEF COMPLAINTS: patient not able to do anything because of tiredness.
She always feels cold and shivering
FELT NEED :As per the patient she wants her childern to with her and no need to improve
anything.
HISTORY TAKING :
HISTORY OF PRESENT ILLNESS: since 2018, Mrs saraswathi was having tremor on left
side in upper and lower limbs and intolerance to cold. In 2018, they went to PSG Combatore
and consulted Dr.Subramaniyam. There she was diagnosed with Stroke and started
medication. Last year during Covid lock down period they came back to erode and
discontinued the drugs for 3 months as she was unable to go to hospital for follow up. On 215
July 2020 they went to Srinivasa Speciality and she was admitted for 1day. They restarted
and also referred to psychiatrist as she was showing symptoms of depression. Now she is
under medication for both the diagnosis.
PAST HISTORY :Bells palsy after Hysterectomy after 2015.
During 2014-15 had join pain and diagnosed RA.
DRUG HISTORY: syndopaplus 1-1/2-1 & Nurokind 3 Tab 0-0-1
FAMILY HISTORY: No similar history of illness
Patient’s Husband passed away
OBJECTIVE
ON OBSERVATION
BODY BUILT -Ectomorphic
FACIAL EXPRESSION - Mask like face
71
ATTITUDE OF LIMBS - Normal
POSTURE -forward stooped posture
Voluntary movements - slow
ON EXAMINATION
SPECIAL SENSES
Vision - Intact
Speech - Intact, Hypophonia
Hearing - Intact
HIGHER CORTICAL FUNCTION
COGNITION
Attention Good
Concentration Fair
Orientation Fair
Memory Fair
Judgement Fair
Problem solving Poor
Decision making Affected
PERCEPTION
Apraxia Fair
Figure ground perception
Spatial orientation
Right left discrimination
72
Adduction 4 4
ELBOW
MOVEMENT RIGHT LEFT
Flexion 4 4
Extension 4 4
Supination 4 4
Pronation 4 4
WRIST
MOVEMENT RIGHT LEFT
Flexion 4 4
Extension 4 4
HIP
MOVEMENT RIGHT LEFT
Flexion 4 4
Extension 4 4
Internal rotation 4 4
External rotation 4 4
Abduction 4 4
Adduction 4 4
KNEE
MOVEMENT LEFT RIGHT
Flexion 4 4
Extension 4 4
ANKLE
MOVEMENT LEFT RIGHT
Dorsi flexion 4 4
Plantar flexion 4 4
73
PAIN: present on both shoulder and lower back after doing repeated movements
TREMMOR: absent
RIGIDITY: absent
COORDINATION TEST
Grass motor Good
Fine motor Fair
Hand to eye Fair
Bilateral Fair
FUNCTIONAL MOBILITY
Modified barthel score :57
Functional independence measure:
77
74
CASE STUDY 3:
SUBJECTIVE
NAME: Santhosh
AGE: 25
SEX : male
OCCUPATION: student
DATE OF ASSESSMENT: 31.01.2023
CLINICAL DIAGNOSIS: haemorrhagic stroke
HAND DOMINANCE: right
CHIEF COMPLAINTS: patient is unable to attend his college classes , unable to move their
right side arm and leg , unable to move independently
HISTORY TAKING :
HISTORY OF PRESENT ILLNESS: with no earlier symptoms , 2 months ago the patient
was attending his regular in person classes where the patient suddenly fainted , he was
immediately take to a clinic in komarapalayam where they administered him with IV
assuming he fainted because of not having his breakfast . once the patient gained his
consciousness he complained of not being able to move his limbs and also exhibited a slurred
speech, the patient was immediately shifted to Vijaya hitec hospital erode where all the
necessary scans and tests were carried out after which the patient was diagnosed with stroke.
On 2nd of December 2022 the patient underwent a craniotomy after a normal recovery the
patient was then referred to Arogya rehabilitation centre for physiotherapy
PAST HISTORY : nill
DRUG HISTORY:
FAMILY HISTORY:
75
OBJECTIVE
ON OBSERVATION
BODY BUILT – mesomorphic
FACIAL EXPRESSION – slight drooping
ATTITUDE OF LIMBS - Normal
POSTURE -forward stooped posture
Voluntary movements - slow
ON EXAMINATION
SPECIAL SENSES
Vision - Intact
Speech - Intact, Hypophonia
Hearing - Intact
HIGHER CORTICAL FUNCTION
COGNITION
Attention Good
Concentration Fair
Orientation Fair
Memory Fair
Judgement Fair
Problem solving Fair
Decision making Poor
PERCEPTION
Apraxia Fair
Figure ground perception
Spatial orientation
Right left discrimination
76
CRANIAL NERVE ASSESSMENT
all cranial nerves intact
MOTOR ASSESSMENT
MUSCEL POWER
SHOULDER
MOVEMENT RIGHT LEFT
Flexion 4 4
Extension 3+ 3
Abduction 3 3+
Adduction 4 4
ELBOW
MOVEMENT RIGHT LEFT
Flexion 4 4
Extension 2 2
Supination 3 3
Pronation 4 4
WRIST
MOVEMENT RIGHT LEFT
Flexion 2 2
Extension 2 2
HIP
MOVEMENT RIGHT LEFT
Flexion 4 4
Extension 4 4
Internal rotation 4 4
External rotation 4 4
Abduction 4 4
Adduction 4 4
77
KNEE
MOVEMENT LEFT RIGHT
Flexion 4 4
Extension 4 4
ANKLE
MOVEMENT LEFT RIGHT
Dorsi flexion 4 4
Plantar flexion 4 4
PAIN: present on both shoulder and lower back after doing repeated movements
TREMMOR: absent
RIGIDITY: absent
COORDINATION TEST
Grass motor Good
Fine motor Fair
Hand to eye Fair
Bilateral Fair
FUNCTIONAL MOBILITY
Modified barthel score :52
Functional independence measure:
74
78