Limbic System
Limbic System
Limbic System
History
Paul Broca (1824-1880): 1878: le grand lobe limbique Refers to a ring of gray matter on the medial aspect of the cerebral hemispheres. James Papez (1883-1958): 1930s: defined a limbic system that might underlie the relationship between emotion and memory (Papez circuit).
Components
Amygdaloid body Hippocampus (seahorse) Cingulate gyus Parahippocampal gyrus Hypothalamus Mamillary bodies Anterior nucleus of thalamus
Functions
Emotional brain Emotional and motivational aspects of behavior. Provides emotional component to learning process:
Especially the amygdala.
Amygdala
Large nuclear group in temporal lobe. Afferents:
Amygdala Connections
Cerebral cortex Olfactory system Thalamus Brainstem reticular formation Stria terminalis Hypothalamus
AMYGDALA
Amygdala Inputs
Olfactory System
AMYGDALA
Corticomedial Nuclear Group Basolateral Nuclear Group Central Nucleus
Amygdala Outputs
Stria Terminalis
AMYGDALA
Corticomedial Nuclear Group Basolateral Nuclear Group Central Nucleus
Nuclei of ANS
Ventral Amygdalofugal Fibers
Medial and lateral temporal lobe Hippocampus Amygdala Entorhinal cortex (24)
Neocortex
Parahippocampal Gyrus
Pathologies (lesions)
Voracious appetite Increased (perverse) sexual activity Docility:
Memory loss:
Damage to hippocampus portion:
Cells undergoing calcium-induced changes associated with memory
Kluver-Bucy Syndrome:
Results from bilateral destruction of amygdala. Characteristics:
Increase in sexual activity. Compulsive tendency to place objects in mouth. Decreased emotionality. Changes in eating behavior. Visual agnosia.