Head Trauma: George Ayoub - Med3
Head Trauma: George Ayoub - Med3
Head Trauma: George Ayoub - Med3
• Coup contrecoup (closed head injury) can damage more than the
impact sites on the brain
• Axon bundes may be torn or twisted, blood vessels may rupture and elevated
ICP can distort the walls of the ventricles.
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• Intracranial hemorrhage: there are several types classified by their
location in the brain. Can range from mild to severe and even life
threatening.
• Epidural hematoma: blood clot on top of the dura. They usually happen at
the side of the head due to a skull fracture (baseball to the temple) that shear
the middle meningeal artery. Diagnosis is made with CT (lens-shaped
hematoma).
• Subdural hematoma: blood clot underneath the dura but outside of the
brain. Diagnosis made with CT (crescent shaped hemorrhage). Can be acute
or chronic:
• Acute: in a young person due to a significant amount of force (shaken-baby syndrome).
• Chronic: in elderly demented patients and alcoholics. Brain atrophy has tensed the
bridging veins or cortical veins (brain injury) so that even minor trauma can cause
shearing producing a slowly evolving hematoma.
• Subarachnoid hemorrhage: trauma is most common cause, also rupture of
aneurysm (saccular), trauma, arteriovenous malformation. Worst headache of
my life. Xanthochromic spinal tap.
• blood breakdown vasospasm ischemic hemorrhage: give nemodipine to reduce
vasospasm.
• High risk of developing communicative/obstructive hydrocephalus.
• Anterior communicating artery most commonly ruptured (associated with ADPCKD)
• Intracerebral hematoma (contrusion): bruise to the brain itself causing
bleeding and swelling inside the brain around the area where the brain was
struck. Can be due to fractures or epi/subdural hematoma. When trauma is
not the cause, it is attributed to long standing HTN in elderly and to bleeding
disorders in young patients and adults or to the use of medications that cause
blood thinning.
• Diffuse axonal injury: happens in angular trauma (spinning in the car stuck on
an angle) causing blurring in the grey-white matter seen on MRI. Often sited
as cause of LOC in patients rendered immediately comatose following head
injury in the absence of a space occupying lesion on CT (although it may
present with sub/epidural hematomas).
• Intraparenchymal hemorrhage: in the brain. Causes: systemic HTN, Charcot-
Bouchard aneurysm (Putamen of basal ganglia), amyloid angiopathy (elderly),
vasculitis, neoplasm…
Chronic SDH with
Subdural hematoma midline shift
due to fracture
Epidural hematoma
Intracranial hemorrhage: Pt
on warfarin
Symptoms
• Epidural: (hyperdense if new – hypodense if old)
• Loss of consciousness followed by a lucid interval then leading to coma.
• Herniation syndrome of the uncus: ipsilateral fixed dilated pupil and
contralateral hemiparesis.
• subdural:
• Acute: There is loss of consciousness without lucid interval following MAJOR
trauma. Neural status from initial trauma not from hematoma.
• Chronic: gradually deteriorating mental status appearing as dementia, often
with headache and language difficulty.
• Intracerebral hematoma (contrusion): bleeding that is sometimes
spontaneous.
• Subarachnoid hemorrhage: nuchal rigidity + worst headache of my life.
• Diffuse axonal injury: symptoms depend on the severity.
• If severe, hemorrhagic foci occur in the corpus callosum and dorsolateral rostral
brain stem
• Axonal retraction balls, microglial stars, degeneration of white matter fiber tracts
• Diagnosed clinically when LOC >6hrs in absence of evidence of intracranial mass or
ischemia.
• Intraparenchymal hemorrhage: neurologic deficits, DAI, carotid artery
injury.
Grading of DAI
• Mild:
• Coma >6-24hrs followed by mild to moderate memory impairment, mild to
moderate disabilities
• Moderate:
• Coma>24hrs followed by confusion and long-lasting amnesia. Mild to severe
memory, behavioral and cognitive deficits.
• Severe:
• Coma lasting months with flexor and extensor posturing. Cognitive, memory,
speech, sensorimotor and personality deficits. Dysautonomia may occur.
Treatment
• Basilar skull fracture: management of the fracture isn’t as important as
viewing the cervical spine by CT.
• Acute epidural hematoma: craniotomy and evacuative procedures
(excellent results).
• Acute subdural hematoma: elevation, mannitol and hyperventilation to
decrease ICP. However, if midline shift (>5mm) is present or <5mm with
symptoms of herniation, craniotomy is performed.
• Chronic subdural hematoma: evacuation to relieve symptoms. Seizure
prophylaxis if post-traumatic seizure (levetiracetam)
• DAI: little can be done – monitor ICP until they wake up of coma.
• Subarachnoid hemorrhage: anticonvulsants and observation.
• Nimodipine for delayed cerebral ischemia neuroprotection.
• Levertiacetam
• Triple H therapy: hypertension, induced hyperventilation, hemodilution also used to
prevent and treat vasospasm. It may cause pulmonary edema, MI, hyponatremia,
cerebral hemorrhage and edema.
complications
• Subdural hematoma treatment:
• Seizures (status epilepticus benzodiazepines)
• ICH
• Failure of brain to expand
• Accumulation of fluid
• Tension pneumocephalus
• Subdural empyema
Increased ICP
• Oxygenation and ventilation
• Keep PaO2 > 100 and PaCO2 30-35
• Mannitol reduces cerebral parenchymal cell water but eventually may
enter CSF and increase ICP.
• Give Lasix after mannitol to reduce brain bulk during surgery. The
main mechanism is believed to be due to decreased brain water
content.
• Hypertonic saline is also effective in reducing ICP if there is no
disruption to BBB.
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