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    Gene Therapy

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    pintoguerrerojannelleandrea
    Medical science has detected many human diseases related to defective genes that cannot be cured through traditional medicine. Gene therapy is a potential method to treat or cure genetic illnesses by inserting foreign DNA into a patient's tissues. There are two main types of gene therapy: somatic gene therapy affects only targeted cells and is short-lived, while germline gene therapy can pass changes to future generations but is controversial. Stem cell gene therapy uses stem cells that can become any cell type and are manipulated to specialize, promoting tissue repair. Stem cells are derived from either embryonic stem cells found in early embryos or somatic stem cells found in adult tissues.

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    Gene Therapy

    Uploaded by

    pintoguerrerojannelleandrea
    61 views18 pages
    Medical science has detected many human diseases related to defective genes that cannot be cured through traditional medicine. Gene therapy is a potential method to treat or cure genetic illnesses by inserting foreign DNA into a patient's tissues. There are two main types of gene therapy: somatic gene therapy affects only targeted cells and is short-lived, while germline gene therapy can pass changes to future generations but is controversial. Stem cell gene therapy uses stem cells that can become any cell type and are manipulated to specialize, promoting tissue repair. Stem cells are derived from either embryonic stem cells found in early embryos or somatic stem cells found in adult tissues.

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    17. Gene Therapy

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    Medical science has detected many human diseases related to defective genes that cannot be cured through traditional medicine. Gene therapy is a potential method to treat or cure genetic illnesses by inserting foreign DNA into a patient's tissues. There are two main types of gene therapy: somatic gene therapy affects only targeted cells and is short-lived, while germline gene therapy can pass changes to future generations but is controversial. Stem cell gene therapy uses stem cells that can become any cell type and are manipulated to specialize, promoting tissue repair. Stem cells are derived from either embryonic stem cells found in early embryos or somatic stem cells found in adult tissues.

    Copyright:

    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
    Download as pptx, pdf, or txt
    61 views18 pages

    Gene Therapy

    Uploaded by

    pintoguerrerojannelleandrea
    Medical science has detected many human diseases related to defective genes that cannot be cured through traditional medicine. Gene therapy is a potential method to treat or cure genetic illnesses by inserting foreign DNA into a patient's tissues. There are two main types of gene therapy: somatic gene therapy affects only targeted cells and is short-lived, while germline gene therapy can pass changes to future generations but is controversial. Stem cell gene therapy uses stem cells that can become any cell type and are manipulated to specialize, promoting tissue repair. Stem cells are derived from either embryonic stem cells found in early embryos or somatic stem cells found in adult tissues.

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    Download as pptx, pdf, or txt
    of 18

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    Gene Therapy 1
    2/8/20XX
    Medical science has detected many human
    diseases related to defective genes. These
    types of diseases are not curable by
    traditional methods like taking readily
    available medicines. Gene therapy is a
    potential method to either treat or cure
    genetic-related human illness.
    Sample Footer Text 2/8/20XX 2
    Sample Footer Text 2/8/20XX 3
    • Human gene therapy was actually first realize in
    1971 when the first recombinant DNA experiments
    were planned. It can be simply viewed as insertion
    foreign DNA into a patients' tissue that hope to
    successfully eradicate the targeted disease.
    • Without a doubt, gene therapy is the most promising
    yet possibly unfavorable medical field being studied.

    Sample Footer Text 2/8/20XX 4


    Basic Process
    • Replacement of mutated gene that causes disease
    with a healthy copy of the gene.
    • Inactivation of mutated gene that is functioning
    improperly
    • Introducing s new gene into the body to help fight a
    disease
    Sample Footer Text 2/8/20XX 5
    Two types of Gene Therapy
    • The idea of gene therapy is based on correcting
    a disease at its root; fixing the abnormal genes
    that appear to certain diseases.
    • Somatic Gene Therapy
    • Germ-line Gene Therapy

    Sample Footer Text 2/8/20XX 6


    Somatic Gene Therapy
    • Somatic Gene Therapy involves the manipulation of
    genes in cells that will be helpful to the patient but
    not inherited to the next generation
    • Affects only the targeted cells in the patient.
    • Short-lived because the cells of most tissues
    ultimately die and are replaced by new cells.
    Sample Footer Text 2/8/20XX 7
    Germ-line Gene Therapy
    • Germ-line Gene Therapy which involves the
    genetic modification of germ cells or the origin
    cells that will pass the change on the next
    generation.
    • Controversy
    • Some people view this type of therapy as unnatural, and liken it to
    “playing God”

    Sample Footer Text 2/8/20XX 8


    Sample Footer Text 2/8/20XX 9
    Stem Cell Gene Therapy
    • Stem cells are mother cells that have the potential
    to become any type of cell in the body.
    • One of the main characteristics of stem cells is their
    ability to self-renew or multiply maintaining the
    potential to develop into other types of cells.

    Sample Footer Text 2/8/20XX 10


    Stem Cell Gene Therapy
    •Stem cells can become cells of the
    blood, heart, bones, skin, muscles,
    brain, among other types of cell.

    Sample Footer Text 2/8/20XX 11


    Stem Cell Gene Therapy
    • Stem Cells Therapy, also known as regenative
    medicine, promotes the repair response of diseased,
    dysfunctional or injured tissue using stem cells or
    their derivates.
    • The cells are manipulated to specialize into specific
    type of cells such as heart muscle cells or blood
    cells.
    Sample Footer Text 2/8/20XX 12
    •Stem cells are derived from
    different sources. Two of which
    are
    •Embryonic Stem Cells
    •Somatic Stem Cells
    Sample Footer Text 2/8/20XX 13
    Stem cells are derived from different sources. Two of which are;

    • Embryonic Stem Cells – ESC are derived from a four-or five-day-


    old human embryo that is in the blastocyst phase development. The
    embryos are usually extras that have been created in IVF (in vitro
    fertilization) clinics where several eggs are fertilized in a test tube then
    implanted into a woman

    Sample Footer Text 2/8/20XX 14


    • Embryonic stem cells (ESCs) are found in the inner cell mass of
    the human blastocyst, an early stage of the developing embryo
    lasting from the 4th to 7th day after fertilization. In normal
    embryonic development, they disappear after the 7 th day, and
    begin to form the three embryonic tissue layer.

    Sample Footer Text 2/8/20XX 15


    Sample Footer Text 2/8/20XX 16
    • Somatic stem cells – SSC are cells that exist
    throughout the body after embryonic development
    and are found inside of different types of tissue.
    • They are remain in a non-dividing state for years until
    activated by disease or tissue injury.

    Sample Footer Text 2/8/20XX 17


    Sample Footer Text 2/8/20XX 18

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