BE Module-1
BE Module-1
BE Module-1
INTRODUCTION TO
BIOLOGY:
Syllabus
INTRODUCTION TO BIOLOGY:
The cell: the basic unit of life, Structure and functions of a
cell. The Plant Cell and animal cell, Prokaryotic and
Eukaryotic cell, Stem cells and their application.
Biomolecules: Properties and functions of Carbohydrates,
Nucleic acids, proteins, lipids. Importance of special
biomolecules; Enzymes (Classification (with one example
each), Properties and functions), vitamins and hormones.
The Cell: the basic unit of life
A cell is the smallest unit of life and the basic building block of
all living things.
Cells are responsible for all life's processes, including providing
structure, taking in nutrients, and converting nutrients into
energy.
The human body is made up of trillions of cells.
Cells are typically too small to see without a microscope.
They are made up of the same major classes of organic
molecules, including: Nucleic acids, Proteins, Carbohydrates,
and Lipids.
The Cell
The Cell
Cells are the structural, functional, and biological units of all
living beings. A cell can replicate itself independently. Hence,
they are known as the building blocks of life.
Each cell contains a fluid called the cytoplasm, which is enclosed
by a membrane. Also present in the cytoplasm are several
biomolecules like proteins, nucleic acids and lipids.
Moreover, cellular structures called cell organelles are suspended
in the cytoplasm.
The study of cells from its basic structure to the functions of
every cell organelle is called Cell Biology. Robert Hooke was the
first Biologist who discovered cells.
The Cell
All organisms are made up of cells. They may be made up of a
single cell (unicellular), or many cells (multicellular).
Cells provide structure to the body and convert the nutrients taken
from the food into energy.
From organism to organism, the count of cells may vary. Humans
have more number of cells compared to that of bacteria.
Cells comprise several cell organelles that perform specialised
functions to carry out life processes.
Every organelle has a specific structure. The hereditary material of
the organisms is also present in the cells.
Characteristics of Cells
Following are the various essential characteristics of cells:
Cells provide structure and support to the body of an organism.
The cell interior is organised into different individual organelles
surrounded by a separate membrane.
The nucleus (major organelle) holds genetic information
necessary for reproduction and cell growth.
Every cell has one nucleus and membrane-bound organelles in
the cytoplasm.
Mitochondria, a double membrane-bound organelle is mainly
responsible for the energy transactions vital for the survival of
the cell.
Characteristics of Cells
Lysosomes digest unwanted materials in the cell.
Endoplasmic reticulum plays a significant role in the internal
organisation of the cell by synthesising selective molecules and
processing, directing and sorting them to their appropriate
locations.
Structure of Cell
The cell structure comprises individual components with specific
functions essential to carry out life’s processes.
These components include- cell wall, cell membrane, cytoplasm,
nucleus, and cell organelles.
Cell Membrane
The cell membrane supports and protects the cell. It controls the
movement of substances in and out of the cells.
It separates the cell from the external environment. The cell
membrane is present in all the cells.
Structure of Cell
Cell Membrane
The cell membrane is the outer covering of a cell within which
all other organelles, such as the cytoplasm and nucleus, are
enclosed.
It is also referred to as the plasma membrane.
By structure, it is a porous membrane (with pores) which permits
the movement of selective substances in and out of the cell.
Besides this, the cell membrane also protects the cellular
component from damage and leakage.
Structure of Cell
Cell Wall
The cell wall is the most prominent part of the plant’s cell
structure.
It is made up of cellulose, hemicellulose and pectin.
The cell wall is present exclusively in plant cells. It protects the
plasma membrane and other cellular components.
The cell wall is also the outermost layer of plant cells.
It is a rigid and stiff structure surrounding the cell membrane.
It provides shape and support to the cells and protects them from
mechanical shocks and injuries.
Structure of Cell
Cytoplasm
Nucleolus
The nucleolus is the site of ribosome synthesis. Also, it is involved in controlling cellular activities and cellular reproduction.
Nuclear membrane
The nuclear membrane protects the nucleus by forming a boundary between the nucleus and other cell organelles.
Chromosomes
Chromosomes play a crucial role in determining the sex of an individual. Each human cells contain 23 pairs of chromosomes.
Endoplasmic reticulum
The endoplasmic reticulum is involved in the transportation of substances throughout the cell. It plays a primary role in the metabolism of carbohydrates,
synthesis of lipids, steroids and proteins.
Structure of Cell
Golgi Bodies
Golgi bodies are called the cell’s post office as it is involved in the transportation of materials
within the cell.
Ribosome
Mitochondria
The mitochondrion is called “the powerhouse of the cell.” It is called so because it produces
ATP – the cell’s energy currency.
Structure of Cell
Lysosomes
Lysosomes protect the cell by engulfing the foreign bodies entering the cell and help in cell
renewal. Therefore, they are known as the cell’s suicide bags.
Chloroplast
Chloroplasts are the primary organelles for photosynthesis. It contains the pigment called
chlorophyll.
Vacuoles
Vacuoles store food, water, and other waste materials in the cell.
Functions of Cell
A cell performs major functions essential for the growth and
development of an organism. Important functions of cell are as
follows:
Provides Support and Structure
All the organisms are made up of cells. They form the
structural basis of all the organisms.
The cell wall and the cell membrane are the main components
that function to provide support and structure to the organism.
For eg., the skin is made up of a large number of cells.
Xylem present in the vascular plants is made of cells that
provide structural support to the plants.
Functions of Cell
Facilitate Growth Mitosis
In the process of mitosis, the parent cell divides into the
daughter cells.
Thus, the cells multiply and facilitate the growth in an
organism.
Allows Transport of Substances
Various nutrients are imported by the cells to carry out various
chemical processes going on inside the cells.
The waste produced by the chemical processes is eliminated
from the cells by active and passive transport.
Functions of Cell
Small molecules such as oxygen, carbon dioxide, and ethanol
diffuse across the cell membrane along the concentration
gradient. This is known as passive transport.
The larger molecules diffuse across the cell membrane through
active transport where the cells require a lot of energy to
transport the substances.
Functions of Cell
Energy Production
Cells require energy to carry out various chemical processes. This
energy is produced by the cells through a process called
photosynthesis in plants and respiration in animals.
Aids in Reproduction
A cell aids in reproduction through the processes called mitosis
and meiosis.
Mitosis is termed as the asexual reproduction where the parent
cell divides to form daughter cells.
Functions of Cell
Aids in Reproduction
Thus, we can understand why cells are known as the structural
and functional unit of life.
This is because they are responsible for providing structure to
the organisms and perform several functions necessary for
carrying out life’s processes.
Plant Cell
“Plant cells are eukaryotic cells with a true nucleus along with
specialized structures called organelles that carry out certain
specific functions.”
Cell Wall
It is a rigid layer which is composed of polysaccharides cellulose,
pectin and hemicellulose. It is located outside the cell membrane.
It also comprises glycoproteins and polymers such as lignin,
cutin, or suberin.
The primary function of the cell wall is to protect and provide
structural support to the cell.
Plant Cell Structure
The plant cell wall is also involved in protecting the cell
against mechanical stress and providing form and structure to
the cell.
It also filters the molecules passing in and out of it.
Cell membrane
It is the semi-permeable membrane that is present within the
cell wall. It is composed of a thin layer of protein and fat.
The cell membrane plays an important role in regulating the
entry and exit of specific substances within the cell.
Plant Cell Structure
For instance, cell membrane keeps toxins from entering inside,
while nutrients and essential minerals are transported across.
Nucleus
The nucleus is a membrane-bound structure that is present only in
eukaryotic cells. The vital function of a nucleus is to store DNA or
hereditary information required for cell division, metabolism and
growth.
1. Nucleolus: It manufactures cells’ protein-producing structures
and ribosomes.
2. Nucleopore: Nuclear membrane is perforated with holes called
nucleopore that allow proteins and nucleic acids to pass through.
Plant Cell Structure
Plastids
They are membrane-bound organelles that have their own
DNA. They are necessary to store starch and to carry out the
process of photosynthesis.
It is also used in the synthesis of many molecules, which form
the building blocks of the cell.
Some of the vital types of plastids and their functions are stated
below:
Leucoplasts
They are found in the non-photosynthetic tissue of plants. They
are used for the storage of protein, lipid and starch.
Plant Cell Structure
Chloroplasts
It is an elongated organelle enclosed by phospholipid
membrane.
The chloroplast is shaped like a disc and the stroma is the fluid
within the chloroplast that comprises a circular DNA.
Each chloroplast contains a green colored pigment called
chlorophyll required for the process of photosynthesis.
The chlorophyll absorbs light energy from the sun and uses it
to transform carbon dioxide and water into glucose.
Plant Cell Structure
Chromoplasts
They are heterogeneous, coloured plastid which is responsible for
pigment synthesis and for storage in photosynthetic eukaryotic
organisms.
Chromoplasts have red, orange and yellow coloured pigments
which provide colour to all ripe fruits and flowers.
Central Vacuole
It occupies around 30% of the cell’s volume in a mature plant
cell. Tonoplast is a membrane that surrounds the central vacuole.
The vital function of the central vacuole apart from storage is to
sustain turgor pressure against the cell wall.
Plant Cell Structure
Golgi Apparatus
They are found in all eukaryotic cells, which are involved in
distributing synthesised macromolecules to various parts of the
cell.
Ribosomes
They are the smallest membrane-bound organelles which
comprise RNA and protein.
They are the sites for protein synthesis, hence, also referred to
as the protein factories of the cell.
Plant Cell Structure
Mitochondria
They are the double-membraned organelles found in the cytoplasm
of all eukaryotic cells.
They provide energy by breaking down carbohydrate and sugar
molecules, hence they are also referred to as the “Powerhouse of the
cell.”
Lysosome
Lysosomes are called suicidal bags as they hold digestive enzymes in
an enclosed membrane.
They perform the function of cellular waste disposal by digesting
worn-out organelles, food particles and foreign bodies in the cell.
In plants, the role of lysosomes is undertaken by the vacuoles.
Plant and Animal Cell
Difference Between Plant and Animal Cell
Prokaryotic Cells
“Prokaryotic cells are the cells that do not have a true nucleus and
membrane-bound organelles.”
Lysosomes
They are known as “suicidal bags” because they possess
hydrolytic enzymes to digest protein, lipids, carbohydrates, and
nucleic acids.
Stem Cells
“Stem cells are special human cells that can develop into many
different types of cells, from muscle cells to brain cells.”
Tissue Regeneration
This is the most important application of stem cells. The stem
cells can be used to grow a specific type of tissue or organ.
This can be helpful in kidney and liver transplants.
The doctors have already used the stem cells from beneath the
epidermis to develop skin tissue that can repair severe burns or
other injuries by tissue grafting.
Applications of Stem Cells
Treatment of Cardiovascular Disease
A team of researchers have developed blood vessels in mice using
human stem cells.
Within two weeks of implantation, the blood vessels formed their
network and were as efficient as the natural vessels.
Treatment of Brain Diseases
Stem cells can also treat diseases such as Parkinson’s disease and
Alzheimer’s.
These can help to replenish the damaged brain cells. Researchers
have tried to differentiate embryonic stem cells into these types of
cells and make it possible to treat diseases.
Applications of Stem Cells
Blood Disease Treatment
The adult hematopoietic stem cells are used to treat cancers,
sickle cell anaemia, and other immunodeficiency diseases.
These stem cells can be used to produce
red blood cells and white blood cells in the body.
Biomolecules
Biomolecules are molecules produced by living organisms and
are essential for life processes like reproduction, growth, and
sustenance.
These molecules are produced by living organisms.
They are divided into four main categories:
1.Carbohydrates
2.Lipids
3.Nucleic acids
4.Proteins
Characteristics of Biomolecules
1) Most of them are organic compounds.
2) They have specific shapes and dimensions.
3) Functional group determines their chemical properties.
4) Many of them are asymmetric.
5) Macromolecules are large molecules and are constructed
from small building block molecules.
6) Building block molecules have simple structure.
7) Biomolecules first gorse by chemical evolution.
Carbohydrates:
Carbohydrates are a class of organic compounds that play a
crucial role in biology and are an important source of energy
for living organisms.
When broken down, they become glucose (blood sugar),
which is the main source of energy for the body. Glucose can
be used immediately or stored for later use.
They are composed of carbon (C), hydrogen (H), and oxygen
(O) atoms and are classified based on their molecular
structure and function.
General formula is (CH2O)n. Glucose- C6H12O6
Types of Carbohydrates
1.Monosaccharides
2.Disaccharides
3.Polysaccharides
Monosaccharide
These are the simplest form of carbohydrates and include
glucose and fructose.
They are easily soluble in water and serve as the primary
source of energy for the body
Disaccharides
These are formed by the condensation of two
monosaccharides and include sucrose, lactose, and maltose.
They are commonly found in sugar and are broken down into
monosaccharides during digestion.
Polysaccharides
These are long chains of monosaccharides linked together.
They serve as storage molecules for energy, such as glycogen
in animals and starch in plants, and also provide structure and
support, such as cellulose in plant cell walls.
Industrial Applications of Carbohydrates
Carbohydrates have a wide range of applications in various
industries, including:
Food and Beverage: Carbohydrates are widely used as
sweeteners, thickeners, and stabilizers in food and beverage
products.
They are also used as energy sources in sports drinks.
Pharmaceuticals: Carbohydrates are used as excipients in
pharmaceutical formulations to improve the stability, solubility,
and bioavailability of drugs.
They are also used as a source of energy in medical nutrition
products.
Industrial Applications of Carbohydrates
Cosmetics: Carbohydrates are used in cosmetic products, such as
moisturizers, shampoos, and conditioners, to provide hydration
and improve skin and hair health.
Biotechnology: Carbohydrates are widely used in the production
of biodegradable plastics, biofuels, and other renewable energy
sources.
Research: Carbohydrates are widely used as research tools in the
fields of immunology, virology, and cellular biology.
Nucleic Acids
What are Nucleic Acids?
Nucleic acids are long-chain polymeric molecules, the monomer (the
repeating unit) is known as the nucleotides and hence sometimes
nucleic acids are referred to as polynucleotides.
DNA and RNA are responsible for the inheritance and transmission
of specific characteristics from one generation to the other. There are
prominently two types of nucleic acids known to us.
Earlier, enzymes were assigned names based on the one who discovered
them. With further research, classification became more comprehensive.
The six kinds of enzymes are hydrolases, oxidoreductases, lyases,
transferases, ligases and isomerases.
Properties of enzymes
Examples of Enzymes
Beverages
Alcoholic beverages generated by fermentation vary a lot based on
many factors.
Based on the type of the plant’s product, which is to be used and the
type of enzyme applied, the fermented product varies.
For example, grapes, honey, hops, wheat, cassava roots, and potatoes
depending upon the materials available. Beer, wines and other drinks
are produced from plant fermentation.
Food Products
Bread can be considered as the finest example of fermentation in our
everyday life.
Examples of Enzymes
Fermentation Process
Examples of Enzymes
Then one can observe that the bread gets puffed up as a result of
fermentation of the sugar by the enzyme action in yeast, which leads
to the formation of carbon dioxide gas.
This process gives the texture to the bread, which would be missing
in the absence of the fermentation process.
Drug Action
Enzyme action can be inhibited or promoted by the use of drugs
which tend to work around the active sites of enzymes.
A small proportion of yeast and sugar is mixed with the batter for
making bread.
Structure of Enzymes
1. Primary Structure : Amino acids are joined together in a linear chain
by amide (peptide) bonds to form enzymes.
Polypeptide or protein refers to the amino acid chain that results.
The DNA sequence of the relevant gene specifies the exact order of
amino acids in the protein.
1) Fat-soluble vitamin
Fat-soluble vitamins are stored in the fat cells and as the name
suggests, these vitamins require fat in order to be absorbed.
Vitamin A, D, E and K are fat-soluble vitamins.
Functions of specific vitamins:
Vitamin B12: Helps form red blood cells and maintain the
central and peripheral nervous systems
Vitamin C: Promotes healthy teeth and gums, helps the body
absorb iron, and maintains healthy tissue
Vitamin D: Decreases bone loss and may decrease fracture
rate
Vitamin K: Necessary for blood clotting
Types of Vitamins
2) Water-soluble vitamin
Water-soluble vitamins are not stored in our body as its excess
gets excrete through the urine. Therefore, these vitamins need to
be replenished constantly. Vitamin B and C are water-soluble
vitamins.
Hormones
“Hormones are chemicals synthesized and produced by the
specialized glands to control and regulate the activity of certain
cells and organs. These specialized glands are known as
endocrine glands.”
They help control how cells and organs work, and affect many
processes, including:
Growth and development, Metabolism, Sexual function,
Reproduction, Mood, Blood sugar, Blood pressure, Fertility,
Sex drive, and Sleep.
Types of Hormones
1) Peptide Hormones
2) Steroid Hormones
1) Peptide Hormones
Peptide hormones are composed of amino acids and are soluble
in water.
Peptide hormones are unable to pass through the cell membrane
as it contains a phospholipid bilayer that stops any fat-insoluble
molecules from diffusing into the cell.
Insulin is an important peptide hormone produced by the
pancreas.
Types of Hormones
2) Steroid Hormones
Unlike peptide hormones, steroid hormones are fat-soluble and
are able to pass through a cell membrane.
Sex hormones such as testosterone, estrogen and progesterone
are examples of steroid hormones.