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The Endocrine System
Endocrine System
- is made up of glands that produce and secretehormones,
chemicalsubstances produced in the body that regulatethe
activityof cells or organs. These hormones regulatethe body's
growth, metabolism (the physical and chemicalprocesses of
the body), and sexual developmentand function.
-the glands are capable ofsynthesizing and releasing special
chemicalmessengers - hormones
Hormones
chemical messengers created by the body. They transfer
information from one set of cells to another to coordinate the
functions of different parts of the body.
Functions of the Hypothalamus
The hypothalamus controls the autonomic
nervous system.
The hypothalamus contains the thirst center,
the hunger center and the body's thermostat.
The hypothalamus controls
thehypophysis (pituitary gland).
The hypothalamus is the site of emotions
and the effect emotions can have on the body.
Pituitary Gland
- also known as the “The Master Gland.”
- is a small pea-sized lump of tissue connected to
the inferior portion of the hypothalamus of the
brain.
-is located at the base of the brain beneath the
hypothalamus and is no larger than a pea. It is
often considered the most important part of the
endocrine system because it produces hormones
that control many functions of other endocrine
glands.
Posterior
Lobe
Antidiuretic hormone (ADH)
Oxytocin
Stimulates the kidneys
to conserve water
Females: causes
contraction of the
uterus and ejection of
breast milk
Males: stimulates
contraction of the
prostate and vas
deferens during
sexual arousal
Pituitary Gland
Pituitary Gland
Anterior Pituitary:
The anterior pituitary gland is the true
glandular part of the pituitary gland. The
function of the anterior pituitary gland is
controlled by the releasing and inhibiting
hormones of the hypothalamus. The anterior
pituitary produces 5 important hormones:
Pituitary Gland ****
Anterior
Lobe
Growth hormone
Prolactin
Adrenocorticotropic
Thyroid-stimulating
Follicle-stimulating
Luteinizing
Stimulates milk
production
Stimulates the adrenal cortex
to release its hormones
Stimulates the thyroid
gland to release its
hormones
Females: stimulates estrogen
production and maturation of
the ova
Males: stimulates sperm
production
Females: stimulates ovulation
and estrogen production
Males: stimulates testosterone
production
Stimulates increase in size
of muscles and bones
FUNCTION OF THE THYROID GLAND
The primary function of your thyroid gland is to secrete
thyroid hormones, which are responsible for controlling your
body’s metabolism. The 2 main thyroid hormones are T3
(triiodothyronine) and T4 (thyroxine). The amount of thyroid
hormones secreted is controlled by another hormone, called
thyroid stimulating hormone (TSH), which is released from
the pituitary gland in your head.
The thyroid hormones are involved in regulating many of
your bodily functions, such as your heart rate, how quickly
you burn calories, and digestion. Babies and children need
adequate amounts of thyroid hormones for brain
development and growth.
I. ADRENAL CORTEX
 the outer portion of the adrenal glands, produces several
hormones that affect blood pressure and blood sugar levels,
growth, as well as some sexual characteristics.
 Death would result if the adrenal cortex were to stop
functioning as it controls metabolic processes that are essential
to life.
Main hormones secreted by the adrenal cortex:
 Aldosterone
 Stimulates body to retain sodium and water
 Important in maintaining Blood Pressure
 Cortisone
 Released when stressed
 Decreases protein synthesis, resulting in slowed tissue repair
 Decreases inflammation
 II. MEDULLA
 inner part of the adrenal glands, produces hormones which
regulate the "fight or flight" response in the body, the body's
reaction to stressful events.
 hormones produced by the medulla:
 EPINEPHRINE – raises blood sugar level, causes nervousness
and perspiration during acute emergencies.
 It also increases muscular power and resistance to fatigue.
 NOREPINEPHRINE - prepares an individual in dealing with
stress and emergencies
 it is also referred to as a stress hormone
 There are no significant effects if this portion of the suprarenal
gland is not working properly.
 EXOCRINE GLAND
The exocrine gland secretes digestive enzymes.
These enzymes are secreted into a network of ducts
that join the main pancreatic duct, which runs the
length of the pancreas.
 ENDOCRINE GLAND
The endocrine gland, which consists of the Islets
of Langerhans, secretes hormones into the
bloodstream.
 Endocrine/Hormonal Function:
 Two of the main pancreatic hormones that are
created and released directly into the
bloodstream are insulin, which acts to lower
blood sugar, and glucagon, which acts to raise
blood sugar.
 Maintaining proper blood sugar levels is crucial to
the functioning of key organs including the brain,
liver, and kidneys.
Insulin is released by
the beta cells which
stimulate the glucose
to be sent to the
body’s cells and
convert unused
glucose to glycogen
Low
Blood sugar
Glucagon is released by
the alpha cells which
stimulate stored
glycogen to be
transformed into
glucose again.
Blood sugar
Elevated
Insulin decreasesblood glucoseconcentrationand
increasesprotein synthesis.
Glucagondoes justthe opposite. Itincreasesblood***
glucoseand decreasesprotein synthesis.
Blood glucose
concentrations
Protein synthesis
Blood glucose
concentrations
Protein synthesis
INSULIN GLUCAGON
 TESTES
 Male sex hormones, as a group, are called
androgens.The principal androgen is
testosterone, which is secreted by the testes.
A small amount is also produced by the
adrenal cortex.
 Production of testosterone begins during
fetal development, continues for a short time
after birth, nearly ceases during childhood,
and then resumes at puberty.
 This steroid hormone is responsible for:
 The growth and development of the male reproductive
structures
 Increased skeletal and muscular growth
 Enlargement of the larynx accompanied by voice changes
 Growth and distribution of body hair
 Increased male sexual drive
 Testosterone secretion is regulated by a negative
feedback system that involves releasing hormones
from the hypothalamus and gonadotropins from
the anterior pituitary.
TESTES
OVARIES
 Two groups of female sex hormones are
produced in the ovaries, the estrogens and
progesterone.These steroid hormones
contribute to the development and function of
the female reproductive organs and sex
characteristics
Gigantism
Gigantism is a rare condition that
causes abnormal growth in
children. It occurs when a child’s
body produces too much growth
hormone. Early diagnosis is
important. Prompt treatment can
stop or slow the changes that may
cause a child to grow larger than
normal. However, the condition
can be hard for parents to detect,
since symptoms of gigantism
might first be seen as normal
childhood growth spurts.
Dwarfism
Is a short stature that results
from a genetic or medical
condition. Dwarfism is
generally defined as an adult
height of 4 feet 10 inches or
less (147 centimeters).The
average adult height among
people with dwarfism is 4
feet (122 cm).
Endocrine system

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Endocrine system

  • 2. Endocrine System - is made up of glands that produce and secretehormones, chemicalsubstances produced in the body that regulatethe activityof cells or organs. These hormones regulatethe body's growth, metabolism (the physical and chemicalprocesses of the body), and sexual developmentand function. -the glands are capable ofsynthesizing and releasing special chemicalmessengers - hormones Hormones chemical messengers created by the body. They transfer information from one set of cells to another to coordinate the functions of different parts of the body.
  • 3. Functions of the Hypothalamus The hypothalamus controls the autonomic nervous system. The hypothalamus contains the thirst center, the hunger center and the body's thermostat. The hypothalamus controls thehypophysis (pituitary gland). The hypothalamus is the site of emotions and the effect emotions can have on the body.
  • 4. Pituitary Gland - also known as the “The Master Gland.” - is a small pea-sized lump of tissue connected to the inferior portion of the hypothalamus of the brain. -is located at the base of the brain beneath the hypothalamus and is no larger than a pea. It is often considered the most important part of the endocrine system because it produces hormones that control many functions of other endocrine glands.
  • 5. Posterior Lobe Antidiuretic hormone (ADH) Oxytocin Stimulates the kidneys to conserve water Females: causes contraction of the uterus and ejection of breast milk Males: stimulates contraction of the prostate and vas deferens during sexual arousal Pituitary Gland
  • 6. Pituitary Gland Anterior Pituitary: The anterior pituitary gland is the true glandular part of the pituitary gland. The function of the anterior pituitary gland is controlled by the releasing and inhibiting hormones of the hypothalamus. The anterior pituitary produces 5 important hormones:
  • 7. Pituitary Gland **** Anterior Lobe Growth hormone Prolactin Adrenocorticotropic Thyroid-stimulating Follicle-stimulating Luteinizing Stimulates milk production Stimulates the adrenal cortex to release its hormones Stimulates the thyroid gland to release its hormones Females: stimulates estrogen production and maturation of the ova Males: stimulates sperm production Females: stimulates ovulation and estrogen production Males: stimulates testosterone production Stimulates increase in size of muscles and bones
  • 8. FUNCTION OF THE THYROID GLAND The primary function of your thyroid gland is to secrete thyroid hormones, which are responsible for controlling your body’s metabolism. The 2 main thyroid hormones are T3 (triiodothyronine) and T4 (thyroxine). The amount of thyroid hormones secreted is controlled by another hormone, called thyroid stimulating hormone (TSH), which is released from the pituitary gland in your head. The thyroid hormones are involved in regulating many of your bodily functions, such as your heart rate, how quickly you burn calories, and digestion. Babies and children need adequate amounts of thyroid hormones for brain development and growth.
  • 9. I. ADRENAL CORTEX  the outer portion of the adrenal glands, produces several hormones that affect blood pressure and blood sugar levels, growth, as well as some sexual characteristics.  Death would result if the adrenal cortex were to stop functioning as it controls metabolic processes that are essential to life. Main hormones secreted by the adrenal cortex:  Aldosterone  Stimulates body to retain sodium and water  Important in maintaining Blood Pressure  Cortisone  Released when stressed  Decreases protein synthesis, resulting in slowed tissue repair  Decreases inflammation
  • 10.  II. MEDULLA  inner part of the adrenal glands, produces hormones which regulate the "fight or flight" response in the body, the body's reaction to stressful events.  hormones produced by the medulla:  EPINEPHRINE – raises blood sugar level, causes nervousness and perspiration during acute emergencies.  It also increases muscular power and resistance to fatigue.  NOREPINEPHRINE - prepares an individual in dealing with stress and emergencies  it is also referred to as a stress hormone  There are no significant effects if this portion of the suprarenal gland is not working properly.
  • 11.  EXOCRINE GLAND The exocrine gland secretes digestive enzymes. These enzymes are secreted into a network of ducts that join the main pancreatic duct, which runs the length of the pancreas.  ENDOCRINE GLAND The endocrine gland, which consists of the Islets of Langerhans, secretes hormones into the bloodstream.
  • 12.  Endocrine/Hormonal Function:  Two of the main pancreatic hormones that are created and released directly into the bloodstream are insulin, which acts to lower blood sugar, and glucagon, which acts to raise blood sugar.  Maintaining proper blood sugar levels is crucial to the functioning of key organs including the brain, liver, and kidneys.
  • 13. Insulin is released by the beta cells which stimulate the glucose to be sent to the body’s cells and convert unused glucose to glycogen Low Blood sugar Glucagon is released by the alpha cells which stimulate stored glycogen to be transformed into glucose again. Blood sugar Elevated
  • 14. Insulin decreasesblood glucoseconcentrationand increasesprotein synthesis. Glucagondoes justthe opposite. Itincreasesblood*** glucoseand decreasesprotein synthesis. Blood glucose concentrations Protein synthesis Blood glucose concentrations Protein synthesis INSULIN GLUCAGON
  • 15.  TESTES  Male sex hormones, as a group, are called androgens.The principal androgen is testosterone, which is secreted by the testes. A small amount is also produced by the adrenal cortex.  Production of testosterone begins during fetal development, continues for a short time after birth, nearly ceases during childhood, and then resumes at puberty.
  • 16.  This steroid hormone is responsible for:  The growth and development of the male reproductive structures  Increased skeletal and muscular growth  Enlargement of the larynx accompanied by voice changes  Growth and distribution of body hair  Increased male sexual drive  Testosterone secretion is regulated by a negative feedback system that involves releasing hormones from the hypothalamus and gonadotropins from the anterior pituitary. TESTES
  • 17. OVARIES  Two groups of female sex hormones are produced in the ovaries, the estrogens and progesterone.These steroid hormones contribute to the development and function of the female reproductive organs and sex characteristics
  • 18. Gigantism Gigantism is a rare condition that causes abnormal growth in children. It occurs when a child’s body produces too much growth hormone. Early diagnosis is important. Prompt treatment can stop or slow the changes that may cause a child to grow larger than normal. However, the condition can be hard for parents to detect, since symptoms of gigantism might first be seen as normal childhood growth spurts.
  • 19. Dwarfism Is a short stature that results from a genetic or medical condition. Dwarfism is generally defined as an adult height of 4 feet 10 inches or less (147 centimeters).The average adult height among people with dwarfism is 4 feet (122 cm).