Human TLR8 is activated upon recognition of Borrelia burgdorferi RNA in the phagosome of human monocytes (Q37309932)

19 August 2017

Human TLR8 is activated upon recognition of Borrelia burgdorferi RNA in the phagosome of human monocytes (English)

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19 August 2017

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Jorge L Cervantes

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19 August 2017

Carson J La Vake

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19 August 2017

Bennett Weinerman

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19 August 2017

Stephanie Luu

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19 August 2017

Caitlin O'Connell

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19 August 2017

Paulo H Verardi

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19 August 2017

Juan C Salazar

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19 August 2017

1 August 2013

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Journal of Leukocyte Biology

19 August 2017

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19 August 2017

94

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19 August 2017

1231-1241

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describes a project that uses

19 August 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3828603/fullTextXML

inferred from PubMed Central ID database lookup

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Activation of human monocytes by live Borrelia burgdorferi generates TLR2-dependent and -independent responses which include induction of IFN-beta

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Genetic association and expression studies indicate a role of toll-like receptor 8 in pulmonary tuberculosis

6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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Phagocytosis of Borrelia burgdorferi, the Lyme disease spirochete, potentiates innate immune activation and induces apoptosis in human monocytes

6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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HIV Gag protein conjugated to a Toll-like receptor 7/8 agonist improves the magnitude and quality of Th1 and CD8+ T cell responses in nonhuman primates

6 September 2017

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6 September 2017

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6 September 2017

TLR signaling pathways

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Hyporesponsiveness to vaccination with Borrelia burgdorferi OspA in humans and in TLR1- and TLR2-deficient mice

6 September 2017

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Human TLR7 or TLR8 independently confer responsiveness to the antiviral compound R-848

6 September 2017

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Quantitative expression of toll-like receptor 1-10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotides

6 September 2017

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The cutaneous response in humans to Treponema pallidum lipoprotein analogues involves cellular elements of both innate and adaptive immunity

6 September 2017

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Cell activation and apoptosis by bacterial lipoproteins through toll-like receptor-2

6 September 2017

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Host defense mechanisms triggered by microbial lipoproteins through toll-like receptors

6 September 2017

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Induction of pro- and anti-inflammatory cytokines by Borrelia burgdorferi lipoproteins in monocytes is mediated by CD14.

6 September 2017

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Genomic sequence of a Lyme disease spirochaete, Borrelia burgdorferi

6 September 2017

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Activation of human monocytic cells by Treponema pallidum and Borrelia burgdorferi lipoproteins and synthetic lipopeptides proceeds via a pathway distinct from that of lipopolysaccharide but involves the transcriptional activator NF-kappa B.

6 September 2017

1 reference

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Dermal inflammation elicited by synthetic analogs of Treponema pallidum and Borrelia burgdorferi lipoproteins.

6 September 2017

1 reference

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Characterization of outer membranes isolated from Borrelia burgdorferi, the Lyme disease spirochete

6 September 2017

1 reference

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Genetic modulation of TLR8 response following bacterial phagocytosis.

6 September 2017

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Bacterial RNA is recognized by different sets of immunoreceptors

14 September 2017

1 reference

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Small interfering RNAs induce macrophage migration inhibitory factor production and proliferation in breast cancer cells via a double-stranded RNA-dependent protein kinase-dependent mechanism.

14 September 2017

1 reference

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Cytokine induction by pyrogens: comparison of whole blood, mononuclear cells, and TLR-transfectants

14 September 2017

1 reference

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Identification of RNA sequence motifs stimulating sequence-specific TLR8-dependent immune responses

14 September 2017

1 reference

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TLR7 is involved in sequence-specific sensing of single-stranded RNAs in human macrophages

14 September 2017

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Oligodeoxynucleotides differentially modulate activation of TLR7 and TLR8 by imidazoquinolines

14 September 2017

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Cutting edge: activation of murine TLR8 by a combination of imidazoquinoline immune response modifiers and polyT oligodeoxynucleotides

14 September 2017

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A distal regulatory region is required for constitutive and IFN-beta-induced expression of murine TLR9 gene.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3828603

Cutting edge: inflammatory signaling by Borrelia burgdorferi lipoproteins is mediated by toll-like receptor 2.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3828603

RIG-I detects infection with live Listeria by sensing secreted bacterial nucleic acids

28 September 2017

1 reference

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VTX-2337 is a novel TLR8 agonist that activates NK cells and augments ADCC.

28 September 2017

1 reference

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Human Lyme arthritis and the immunoglobulin G antibody response to the 37-kilodalton arthritis-related protein of Borrelia burgdorferi

26 June 2018

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Toll-like receptor 2 plays a pivotal role in host defense and inflammatory response to Borrelia burgdorferi

26 June 2018

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Click-mediated labeling of bacterial membranes through metabolic modification of the lipopolysaccharide inner core.

26 June 2018

1 reference

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Expression of Toll-like receptors 7, 8, and 9 in primary Sjögren's syndrome.

2 September 2018

1 reference

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Toll-like receptor responses in IRAK-4-deficient neutrophils

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3828603

Bacterial recognition by TLR7 in the lysosomes of conventional dendritic cells

2 September 2018

1 reference

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Multiple signaling pathways contribute to synergistic TLR ligand-dependent cytokine gene expression in human monocyte-derived macrophages and dendritic cells.

2 September 2018

1 reference

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Differential involvement of BB loops of toll-IL-1 resistance (TIR) domain-containing adapter proteins in TLR4- versus TLR2-mediated signal transduction.

2 September 2018

1 reference

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Toll-like receptor 2 functions as a pattern recognition receptor for diverse bacterial products.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3828603

The role of CD14 in signaling mediated by outer membrane lipoproteins of Borrelia burgdorferi.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3828603

Activation of human monocytic cells by Borrelia burgdorferi and Treponema pallidum is facilitated by CD14 and correlates with surface exposure of spirochetal lipoproteins

2 September 2018

1 reference

12 December 2020

Toll-like receptor 2 is required for innate, but not acquired, host defense to Borrelia burgdorferi

1 reference

12 December 2020

Intracellular route and transcriptional competence of polyethylenimine-DNA complexes

1 reference

12 December 2020

Signaling through CD14 attenuates the inflammatory response to Borrelia burgdorferi, the agent of Lyme disease

1 reference

12 December 2020

TLR-TLR cross talk in human PBMC resulting in synergistic and antagonistic regulation of type-1 and 2 interferons, IL-12 and TNF-alpha

1 reference

12 December 2020

Preparation of cell cultures and vaccinia virus stocks

1 reference

12 December 2020

IRAK4 in TLR/IL-1R signaling: possible clinical applications

1 reference

12 December 2020

Characterization of cationic liposome-mediated gene transfer in vivo by intravenous administration

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12 December 2020

Identifiers

DOI

10.1189/JLB.0413206

1 reference

19 August 2017

1 reference

19 August 2017

PubMed publication ID

23906644

1 reference