paliperidone (Q423292)

Paliperidone (English)

3 October 2016

chemical formula

C₂₃H₂₇FN₄O₃

1 reference

Paliperidone (English)

19 November 2016

canonical SMILES

CC1=C(C(=O)N2CCCC(C2=N1)O)CCN3CCC(CC3)C4=NOC5=C4C=CC(=C5)F

1 reference

Paliperidone (English)

19 November 2016

defined daily dose

6 milligram

https://www.whocc.no/atc_ddd_index/?code=N05AX13

oral administration

1 reference

reference URL

2.5 milligram

parenteral route of administration

1 reference

reference URL

https://www.whocc.no/atc_ddd_index/?code=N05AX13

1 reference

14 February 2018

medical condition treated

psychosis

1 reference

Drug Indications Extracted from FAERS

2 October 2018

schizoaffective disorder

1 reference

Drug Indications Extracted from FAERS

2 October 2018

mental disorder

1 reference

Drug Indications Extracted from FAERS

significant drug interaction

2 October 2018

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

(RS)-methadone

1 reference

A reference set of clinically relevant adverse drug-drug interactions

droperidol

1 reference

A reference set of clinically relevant adverse drug-drug interactions

apomorphine

1 reference

A reference set of clinically relevant adverse drug-drug interactions

pimozide

1 reference

A reference set of clinically relevant adverse drug-drug interactions

zuclopenthixol

1 reference

A reference set of clinically relevant adverse drug-drug interactions

haloperidol

1 reference

A reference set of clinically relevant adverse drug-drug interactions

(RS)-hydroxyzine

1 reference

A reference set of clinically relevant adverse drug-drug interactions

(RS)-sulpiride

1 reference

A reference set of clinically relevant adverse drug-drug interactions

tetrabenazine

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

clonidine

1 reference

A reference set of clinically relevant adverse drug-drug interactions

zuclopenthixol

1 reference

A reference set of clinically relevant adverse drug-drug interactions

(RS)-sulpiride

1 reference

A reference set of clinically relevant adverse drug-drug interactions

trimipramine

1 reference

A reference set of clinically relevant adverse drug-drug interactions

amitriptyline

1 reference

A reference set of clinically relevant adverse drug-drug interactions

droperidol

1 reference

A reference set of clinically relevant adverse drug-drug interactions

pimozide

1 reference

A reference set of clinically relevant adverse drug-drug interactions

aripiprazole

1 reference

A reference set of clinically relevant adverse drug-drug interactions

haloperidol

1 reference

A reference set of clinically relevant adverse drug-drug interactions

quetiapine

1 reference

A reference set of clinically relevant adverse drug-drug interactions

levodopa

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

clozapine

1 reference

A reference set of clinically relevant adverse drug-drug interactions

apomorphine

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

pulseless electrical activity

1 reference

A reference set of clinically relevant adverse drug-drug interactions

cardiotoxicity

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

pulseless electrical activity

1 reference

A reference set of clinically relevant adverse drug-drug interactions

cardiotoxicity

1 reference

A reference set of clinically relevant adverse drug-drug interactions

(±)-promethazine

1 reference

A reference set of clinically relevant adverse drug-drug interactions

trimipramine

1 reference

A reference set of clinically relevant adverse drug-drug interactions

amitriptyline

1 reference

A reference set of clinically relevant adverse drug-drug interactions

quetiapine

1 reference

A reference set of clinically relevant adverse drug-drug interactions

clozapine

1 reference

A reference set of clinically relevant adverse drug-drug interactions

buprenorphine

1 reference

A reference set of clinically relevant adverse drug-drug interactions

aripiprazole

1 reference

A reference set of clinically relevant adverse drug-drug interactions

(RS)-sulpiride

1 reference

A reference set of clinically relevant adverse drug-drug interactions

clonidine

orthostatic intolerance

1 reference

A reference set of clinically relevant adverse drug-drug interactions

tetrabenazine

1 reference

A reference set of clinically relevant adverse drug-drug interactions

legal status (medicine)

boxed warning

1 reference

reference URL

https://nctr-crs.fda.gov/fdalabel/ui/spl-summaries/criteria/343802

Australian pregnancy category B3

FDA-sourced list of all drugs with black box warnings (Use Download Full Results and View Query links. (English)

pregnancy category

1 reference

imported from Wikimedia project

English Wikipedia

US pregnancy category C

1 reference

imported from Wikimedia project

English Wikipedia

LiverTox likelihood score

LiverTox toxicity likelihood category E

1 reference

8 April 2021

https://www.ncbi.nlm.nih.gov/books/n/livertox/Paliperidone

10 March 2016

0 references

0 references

Paliperidone

0 references

Identifiers

NL CR AUT ID

ph952545

subject named as

paliperidon

0 references

InChI

InChI=1S/C23H27FN4O3/c1-14-17(23(30)28-9-2-3-19(29)22(28)25-14)8-12-27-10-6-15(7-11-27)21-18-5-4-16(24)13-20(18)31-26-21/h4-5,13,15,19,29H,2-3,6-12H2,1H3

1 reference

Paliperidone (English)

19 November 2016

2 references

Paliperidone (English)

19 November 2016

ChEBI release 2020-09-01

CAS Registry Number

144598-75-4

2 references

paliperidone (English)

19 November 2016

https://commonchemistry.cas.org/detail?cas_rn=144598-75-4

8 April 2021

1 reference

Paliperidone (English)

19 November 2016

2 references

Paliperidone (English)

19 November 2016

ChEBI ID

83804

mapping relation type

2 references

PALIPERIDONE (English)

19 November 2016

International Chemical Identifier

InChI

InChI=1S/C23H27FN4O3/c1-14-17(23(30)28-9-2-3-19(29)22(28)25-14)8-12-27-10-6-15(7-11-27)21-18-5-4-16(24)13-20(18)31-26-21/h4-5,13,15,19,29H,2-3,6-12H2,1H3

1 reference

PALIPERIDONE (English)

19 November 2016

2 references

inferred from InChIKey

MSBNK-Athens_Univ-AU156801

1 reference

MassBank accession ID

0 references

MSBNK-Athens_Univ-AU156802

0 references

MSBNK-Athens_Univ-AU156803

0 references

MSBNK-Athens_Univ-AU156804

0 references

MSBNK-Athens_Univ-AU156805

0 references

SPLASH

splash10-004i-0010900000-dfa5205279a00e3db1e5

0 references

splash10-0a4i-0090300000-40916890e9a9a7068fa9

0 references

splash10-0a4i-0090000000-e69a1027f43e06f96a84

0 references

splash10-0a4i-0090000000-5a71379b6aa632f43ea0

0 references

HSDB ID

8148

1 reference

Hazardous Substances Data Bank

28 October 2019

Paliperidone (English)

reason for deprecated rank

10 May 2021

DSSTox substance ID

DTXSID7049059

applies to other chemical entity

1 reference

DSSTOX compound identifier

DTXCID2028985

reason for deprecated rank

applies to other chemical entity

0 references

0 references

0 references

1 reference

ECHA Substance Infocard database

ECHA Substance Infocard ID

100.117.604

27 December 2018

ECHA Substance Infocard ID

3-{2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl}-9-hydroxy-2-methyl-4H,6H,7H,8H,9H-pyrido[1,2-a]pyrimidin-4-one (English)

quotation

CAS no.: 144598-75-4 (English)

100.117.604

1 reference

ECHA Substance Infocard database

ECHA Substance Infocard ID

100.117.604

27 December 2018

3-{2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl}-9-hydroxy-2-methyl-4H,6H,7H,8H,9H-pyrido[1,2-a]pyrimidin-4-one (English)

quotation

CAS no.: 144598-75-4 (English)

1 reference

Guide to Pharmacology Ligand ID

Paliperidone (English)

publication date

17 November 2015

7258

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

7258

paliperidone (English)

19 November 2016

1 reference

paliperidone (English)

19 November 2016

DrugBank ID

DB01267

1 reference

Human Metabolome Database ID

HMDB0015396

2 references

based on heuristic

inferred from InChIKey

2 references

paliperidone (English)

19 November 2016

MedlinePlus drug identifier

a607005

oral administration

0 references

a615032

intramuscular injection

0 references

NDF-RT ID

N0000176080

1 reference

paliperidone (English)

19 November 2016

0 references

1 reference

1 reference

https://docs.openalex.org/download-snapshot/snapshot-data-format

Paliperidone (English)

19 January 2016

1 reference

28 October 2013

Microsoft Academic ID

0 references

1 reference

26 January 2022

UMLS CUI

C0753678

1 reference

paliperidone (English)