Abdullatif M Amneenah

Background: Neonatal hyperbilirubinemia (NH) is among the common neonatal morbidities. Phototherapy is its most used therapeutic intervention. Different delivering systems and types are currently available. Aim of Study: The aim of the study was to evaluate the electrolyte changes in neonates receiving phototherapy with find out the high risk neonates for electrolyte changes and to compare the effect on electrolytes in preterm and term neonates receiving phototherapy. Subjects and Methods: This was a clinical trial, the study was conducted in special care baby unit at Al-Wahda Teaching Hospital, Derna, Libya over a period of six months from August 1 st 2021 to February 2022. Sixty newborns 34 Male, 26 Female were enrolled in the study. Results: There was a significant decrease in total bilirubin, sodium, calcium, and magnesium levels after phototherapy. However, there is a slight change in potassium, chloride, phosphorous, and ALP but without statistically significant difference. Conclusion: Serum electrolytes significantly decreased during phototherapy. This study shows that neonates exposed to phototherapy are at a risk of developing electrolyte imbalances and consequently their complications. Hence, close monitoring of such babies are needed to prevent imbalances and their untoward consequences.

Background: The febrile seizure is the commonest form of seizure in children. Several hypotheses propose that neurotransmitters and trace elements have a role in the beginning of a febrile seizure. Inhibitory pathways in the central nervous system (CNS) can be affected by zinc, an essential component of many enzymes. Aim and objectives: This study aimed to determine the relation between serum zinc level and febrile seizures. Subjects and methods: This prospective case control study was carried in Al-Wahda hospital-pediatrics department in Derna city in the northeastern part of Libya in the period between March 2019 to March 2020. This study comprised 120 children aged between 2 months and 6 years. They were divided to 3 groups: 40 children with febrile seizures, 40 children with fever and no seizures, and 40 healthy children. Results: Zinc levels varied significantly amongst the three groups investigated. The differences between the groups with and without febrile seizures, as well as between febrile seizure groups and the controls, are also notable. The seizure-free group and the controls, on the other hand, showed no considerable differences. Conclusion: According to the current findings, serum levels of zinc were lower in children with febrile seizures. Seizures in febrile children may be facilitated by zinc deficiency.

Background: Neonatal jaundice is a very common condition. Serious unconjugated hyperbilirubinemia may result in neurological dysfunction as catastrophic as kernicterus. Phototherapy is the method of choice in treatment of hyperbilirubinemia. Aim and objectives: the aim of the study was to assess the accuracy of transcutaneous bilirubin measurement during phototherapy by using skin patch and comparing this with skin and serum bilirubin measurement at the same time. Subjects and methods: This was an observational prospective study was conducted in special care baby unit at Al-wahda teaching hospital-Derna-Libya over a period of nine months (June 1 st 2021 to March 2022).Eighty (80) newborn (41 Male, 39 Female) were enrolled in the study .Transcutaneous bilirubin measurement from skin over sternum, skin under patch at Rt. Side of chest, simultaneously serum bilirubin sample were collected. Results: during phototherapy; the mean± SD TSB (14.94 ± 4.57 μmol/L) and mean± SD TCBC (13.52 ± 4.84) and at skin level was 9.45 ± 3.62. Bland-Altman plot showed significant agreement between TcB from patched site and TSB Conclusion: TCB measurements correlate strongly with TSB levels during and after PT. However, as a result of the wide and clinically relevant disagreement between TCB and TSB measurements during the PT phase, a TCB device cannot be recommended for monitoring bilirubin level during PT in our opinion. However, based on our results, we would advocate the use of TCB for TSB 'rebound' measurements at 12 hours after PT to avoid unnecessary serum sampling.

measurement is an acceptable method for identification of hyperbilirubinemia requiring treatment in preterm newborns. We recommend abdominal region as a reliable site in infants of gestational age ≤34 wk for measuring transcutaneous bilirubin.

Background: Neonatal jaundice is a very common condition. Serious unconjugated hyperbilirubinemia may result in neurological dysfunction as catastrophic as kernicterus. Phototherapy is the method of choice in treatment of hyperbilirubinemia. Aim and objectives:  the aim of the study was to assess the accuracy of transcutaneous bilirubin measurement during phototherapy by using skin patch and comparing this with skin and serum bilirubin measurement at the same time.   Subjects and methods: This was an observational prospective study was conducted in special care baby unit at Al-wahda teaching hospital –Derna-Libya over a period of nine months (June 1st 2021 to March 2022).Eighty (80) newborn (41 Male, 39 Female) were enrolled in the study .Transcutaneous bilirubin measurement from skin over sternum, skin under patch at Rt. Side of chest, simultaneously serum bilirubin sample were collected.  Results: during phototherapy; the mean± SD TSB (14.94 ± 4.57 μmol/L) and mean± SD TCBC (13.52...

Background: Neonatal jaundice is a very common condition. Serious unconjugated hyperbilirubinemia may result in neurological dysfunction as catastrophic as kernicterus. Phototherapy is the method of choice in treatment of hyperbilirubinemia. Aim and objectives: the aim of the study was to assess the accuracy of transcutaneous bilirubin measurement during phototherapy by using skin patch and comparing this with skin and serum bilirubin measurement at the same time. Subjects and methods: This was an observational prospective study was conducted in special care baby unit at Al-wahda teaching hospital-Derna-Libya over a period of nine months (June 1 st 2021 to March 2022).Eighty (80) newborn (41 Male, 39 Female) were enrolled in the study .Transcutaneous bilirubin measurement from skin over sternum, skin under patch at Rt. Side of chest, simultaneously serum bilirubin sample were collected. Results: during phototherapy; the mean± SD TSB (14.94 ± 4.57 μmol/L) and mean± SD TCBC (13.52 ± 4.84) and at skin level was 9.45 ± 3.62. Bland-Altman plot showed significant agreement between TcB from patched site and TSB Conclusion: TCB measurements correlate strongly with TSB levels during and after PT. However, as a result of the wide and clinically relevant disagreement between TCB and TSB measurements during the PT phase, a TCB device cannot be recommended for monitoring bilirubin level during PT in our opinion. However, based on our results, we would advocate the use of TCB for TSB 'rebound' measurements at 12 hours after PT to avoid unnecessary serum sampling.

Background: Neonatal jaundice is a very common condition. Serious unconjugated hyperbilirubinemia may result in neurological dysfunction as catastrophic as kernicterus. Phototherapy is the method of choice in treatment of hyperbilirubinemia. Aim and objectives: the aim of the study was to assess the accuracy of transcutaneous bilirubin measurement during phototherapy by using skin patch and comparing this with skin and serum bilirubin measurement at the same time. Subjects and methods: This was an observational prospective study was conducted in special care baby unit at Al-wahda teaching hospital-Derna-Libya over a period of nine months (June 1 st 2021 to March 2022).Eighty (80) newborn (41 Male, 39 Female) were enrolled in the study .Transcutaneous bilirubin measurement from skin over sternum, skin under patch at Rt. Side of chest, simultaneously serum bilirubin sample were collected. Results: during phototherapy; the mean± SD TSB (14.94 ± 4.57 μmol/L) and mean± SD TCBC (13.52 ± 4.84) and at skin level was 9.45 ± 3.62. Bland-Altman plot showed significant agreement between TcB from patched site and TSB Conclusion: TCB measurements correlate strongly with TSB levels during and after PT. However, as a result of the wide and clinically relevant disagreement between TCB and TSB measurements during the PT phase, a TCB device cannot be recommended for monitoring bilirubin level during PT in our opinion. However, based on our results, we would advocate the use of TCB for TSB 'rebound' measurements at 12 hours after PT to avoid unnecessary serum sampling.