- Applied Mathematics, Modeling and Simulation, Mathematical Modelling, Statistics, Remote Sensing, Unmanned Aerial Vehicle (UAV), and 9 morePhotogrammetry, Forest Ecology, Forest Ecology And Management, Forestry, Ecology, Ecotoxicology, Metal ecotoxicology, Environmental modeling, and Environmental Modeling & Simulationedit
Although it is widely recognized that climate change will require a major spatial reorganization of forests, our ability to predict exactly how and where forest characteristics and distributions will change has been rather limited.... more
Although it is widely recognized that climate change will require a major spatial reorganization of forests, our ability to predict exactly how and where forest characteristics and distributions will change has been rather limited. Current efforts to predict future distribution of forested ecosystems as a function of climate include species distribution models (for fine scale predictions) and potential vegetation climate envelope models (for coarse-grained, large scale predictions). Here we develop and apply an intermediate approach wherein we use stand-level tolerances of environmental stressors to understand forest distributions and vulnerabilities to anticipated climate change. In contrast to other existing models, this approach can be applied at a continental scale while maintaining a direct link to ecologically relevant, climate-related stressors. We first demonstrate that shade, drought, and waterlogging tolerances of forest stands are strongly correlated with climate and edaphic conditions in the conterminous US. This discovery allows the development of a Tolerance Distribution Model (TDM), a novel quantitative tool to assess landscape level impacts of climate change. We then focus on evaluating the implications of the drought TDM. Using an ensemble of 17 climate change models to drive this TDM, we estimate that 18% of US ecosystems are vulnerable to drought-related stress over the coming century. Vulnerable areas include mostly the Midwest US and Northeast US, as well as high elevation areas of the Rocky Mountains. We also infer stress incurred by shifting climate should create an opening for the establishment of forest types not currently seen in the conterminous US.
Research Interests:
• We investigate the consequences of global warming scenarios in Quebec forests using an inhomo-geneous Markov chain model. This allows us to unify predictions from climate change models and mechanistic models of forest disturbance and... more
• We investigate the consequences of global warming scenarios in Quebec forests using an inhomo-geneous Markov chain model. This allows us to unify predictions from climate change models and mechanistic models of forest disturbance and growth and allows predicting the potential impacts of climate change on Quebec forests. The model predicts changes in fire rate in Quebec hardwood forests as well as possible growth enhancements due to increasing CO 2 and temperature. • Our original method consists of three steps. (1) We estimate biomass transition matrices from forest inventories using the Bayesian method. (2) We incorporate dynamic disturbance and forest growth scenarios, and (3) we simulate transient dynamics and stationary states. This modelling approach allows for sensitivity analysis and quantitative assessment effects of variability of climate change scenarios. • We have considered published climate change scenarios for Quebec and conducted simulations for the most extreme predictions (the smallest and largest predicted changes). None of the considered scenarios is able to counterbalance the currently observed trend of increasing biomass in the next 40 years. By the beginning of 2090, the extreme scenarios diverge within about 5% mean biomass. • Synthesis. In this work, we have developed an original modelling approach incorporating time-inhomogeneous effects within the Markov chain framework. We applied this approach to examine effects of climate change in Quebec's forests. The results demonstrate that the current trend of increase in forest biomass is robust with respect to a broad range of climate change scenarios. This study was not possible with previously employed homogeneous Markov chain models. The model can also be extended to include different harvesting methods and land-use practices, enabling better long-term management of Quebec's forest.
Research Interests:
Unmanned Aerial Vehicles (UAVs) are already broadly employed for 3D modeling of large objects such as trees and monuments via photogrammetry. The usual workflow includes two distinct steps: image acquisition with UAV and computationally... more
Unmanned Aerial Vehicles (UAVs) are already broadly employed for 3D modeling of large objects such as trees and monuments via photogrammetry. The usual workflow includes two distinct steps: image acquisition with UAV and computationally demanding post-flight image processing. Insufficient feature overlaps across images is a common shortcoming in post-flight image processing resulting in the failure of 3D reconstruction. Here we propose a real-time control system that overcomes this limitation by targeting specific spatial locations for image acquisition thereby providing sufficient feature overlap. We initially benchmark several implementations of the Scale-Invariant Feature Transform (SIFT) feature identification algorithm to determine whether they allow real-time execution on the low-cost processing hardware embedded on the UAV. We then experimentally test our UAV platform in virtual and real-life environments. The presented architecture consistently decreases failures and improves the overall quality of 3D reconstructions.
Research Interests: Remote Sensing, Photogrammetry, Embedded Systems, 3D Reconstruction, 3D visualisation, and 9 moreReal Time Embedded Systems, 3d Modeling, UAV systems, Unmanned Aerial Vehicle (UAV), Drones, Design and Implementation of the Closed Loop Control of a Quad Rotor UAV for Stability, UAV for Photogrammetry, Remote Sensing and GIS applications in Forestry, and Environmental Robotics
Detailed, precise, three-dimensional (3D) representations of individual trees are a prerequisite for an accurate assessment of tree competition, growth, and morphological plasticity. Until recently, our ability to measure the... more
Detailed, precise, three-dimensional (3D) representations of individual trees are a prerequisite for an accurate assessment of tree competition, growth, and morphological plasticity. Until recently, our ability to measure the dimensionality, spatial arrangement, shape of trees, and shape of tree components with precision has been constrained by technological and logistical limitations and cost. Traditional methods of forest biometrics provide only partial measurements and are labor intensive. Active remote technologies such as LiDAR operated from airborne platforms provide only partial crown reconstructions. The use of terrestrial LiDAR is laborious, has portability limitations and high cost. In this work we capitalized on recent improvements in the capabilities and availability of small unmanned aerial vehicles (UAVs), light and inexpensive cameras, and developed an affordable method for obtaining precise and comprehensive 3D models of trees and small groups of trees. The method employs slow-moving UAVs that acquire images along predefined trajectories near and around targeted trees, and computer vision-based approaches that process the images to obtain detailed tree reconstructions. After we confirmed the potential of the methodology via simulation we evaluated several UAV platforms, strategies for image acquisition, and image processing algorithms. We present an original, step-by-step workflow which utilizes open source programs and original software. We anticipate that future development and applications of our method will improve our understanding of forest self-organization emerging from the competition among trees, and will lead to a refined generation of individual-tree-based forest models.
Research Interests: Forestry, Remote Sensing, Photogrammetry, Plant Ecology, Ecology, and 13 more3D Reconstruction, 3D visualisation, Forest Ecology, 3d Modeling, UAV systems, Trees, Unmanned Aerial Vehicle (UAV), Drones, UAV for Remote Sensing, UAV for Photogrammetry, UAV MODELLING AND SIMULATION, Drones and Robots, and Remote Sensing and GIS applications in Forestry
In this paper we revisit the classic theory of forest succession that relates shade tolerance and species replacement and assess its validity to understand patch-mosaic patterns of forested ecosystems of the USA. We introduce a... more
In this paper we revisit the classic theory of forest succession that relates shade tolerance and species replacement and assess its validity to understand patch-mosaic patterns of forested ecosystems of the USA. We introduce a macroscopic parameter called the “shade tolerance index” and compare it to the classic continuum index in southern Wisconsin forests. We exemplify shade tolerance driven succession in White Pine-Eastern Hemlock forests using computer simulations and analyzing approximated chronosequence data from the USDA FIA forest inventory. We describe this parameter across the last 50 years in the ecoregions of mainland USA, and demonstrate that it does not correlate with the usual macroscopic characteristics of stand age, biomass, basal area, and biodiversity measures. We characterize the dynamics of shade tolerance index using transition matrices and delimit geographical areas based on the relevance of shade tolerance to explain forest succession. We conclude that shade tolerance driven succession is linked to climatic variables and can be considered as a primary driving factor of forest dynamics mostly in central-north and northeastern areas in the USA. Overall, the shade tolerance index constitutes a new quantitative approach that can be used to understand and predict succession of forested ecosystems and biogeographic patterns.
Research Interests:
Forest dynamics are highly dimensional phenomena that are not fully understood theoretically. Forest inventory datasets offer unprecedented opportunities to model these dynamics, but they are analytically challenging due to high... more
Forest dynamics are highly dimensional phenomena that are not fully understood theoretically. Forest inventory datasets offer unprecedented opportunities to model these dynamics, but they are analytically challenging due to high dimensionality and sampling irregularities across years. We develop a data-intensive methodology for predicting forest stand dynamics using such datasets. Our methodology involves the following steps: 1) computing stand level characteristics from individual tree measurements, 2) reducing the characteristic dimensionality through analyses of their correlations, 3) parameterizing transition matrices for each uncorrelated dimension using Gibbs sampling, and 4) deriving predictions of forest developments at different timescales. Applying our methodology to a forest inventory database from Quebec, Canada, we discovered that four uncorrelated dimensions were required to describe the stand structure: the biomass, biodiversity, shade tolerance index and stand age. We were able to successfully estimate transition matrices for each of these dimensions. The model predicted substantial short-term increases in biomass and longer-term increases in the average age of trees, biodiversity, and shade intolerant species. Using highly dimensional and irregularly sampled forest inventory data, our original data-intensive methodology provides both descriptions of the short-term dynamics as well as predictions of forest development on a longer timescale. This method can be applied in other contexts such as conservation and silviculture, and can be delivered as an efficient tool for sustainable forest management.
Research Interests:
Research Interests:
Aim Current interest in forecasting changes to species ranges has resulted in a multitude of approaches to species distribution models (SDMs). However, most approaches include only a small subset of the available information, and many... more
Aim
Current interest in forecasting changes to species ranges has resulted in a multitude of approaches to species distribution models (SDMs). However, most approaches include only a small subset of the available information, and many ignore smaller-scale processes such as growth, fecundity and dispersal. Furthermore, different approaches often produce divergent predictions with no simple method to reconcile them. Here, we present a flexible framework for integrating models at multiple scales using hierarchical Bayesian methods.
Location
Eastern North America (as an example).
Methods
Our framework builds a metamodel that is constrained by the results of multiple sub-models and provides probabilistic estimates of species presence. We applied our approach to a simulated dataset to demonstrate the integration of a correlative SDM with a theoretical model. In a second example, we built an integrated model combining the results of a physiological model with presence–absence data for sugar maple (Acer saccharum), an abundant tree native to eastern North America.
Results
For both examples, the integrated models successfully included information from all data sources and substantially improved the characterization of uncertainty. For the second example, the integrated model outperformed the source models with respect to uncertainty when modelling the present range of the species. When projecting into the future, the model provided a consensus view of two models that differed substantially in their predictions. Uncertainty was reduced where the models agreed and was greater where they diverged, providing a more realistic view of the state of knowledge than either source model.
Main conclusions
We conclude by discussing the potential applications of our method and its accessibility to applied ecologists. In ideal cases, our framework can be easily implemented using off-the-shelf software. The framework has wide potential for use in species distribution modelling and can drive better integration of multi-source and multi-scale data into ecological decision-making.
Current interest in forecasting changes to species ranges has resulted in a multitude of approaches to species distribution models (SDMs). However, most approaches include only a small subset of the available information, and many ignore smaller-scale processes such as growth, fecundity and dispersal. Furthermore, different approaches often produce divergent predictions with no simple method to reconcile them. Here, we present a flexible framework for integrating models at multiple scales using hierarchical Bayesian methods.
Location
Eastern North America (as an example).
Methods
Our framework builds a metamodel that is constrained by the results of multiple sub-models and provides probabilistic estimates of species presence. We applied our approach to a simulated dataset to demonstrate the integration of a correlative SDM with a theoretical model. In a second example, we built an integrated model combining the results of a physiological model with presence–absence data for sugar maple (Acer saccharum), an abundant tree native to eastern North America.
Results
For both examples, the integrated models successfully included information from all data sources and substantially improved the characterization of uncertainty. For the second example, the integrated model outperformed the source models with respect to uncertainty when modelling the present range of the species. When projecting into the future, the model provided a consensus view of two models that differed substantially in their predictions. Uncertainty was reduced where the models agreed and was greater where they diverged, providing a more realistic view of the state of knowledge than either source model.
Main conclusions
We conclude by discussing the potential applications of our method and its accessibility to applied ecologists. In ideal cases, our framework can be easily implemented using off-the-shelf software. The framework has wide potential for use in species distribution modelling and can drive better integration of multi-source and multi-scale data into ecological decision-making.
Research Interests:
Increasing occurrence of droughts is a major environmental concern, however its consequences on forested ecosystems are not fully understood at the landscape level. Here we link the forest shade tolerance index to soil moisture in the... more
Increasing occurrence of droughts is a major environmental concern, however its consequences on forested ecosystems are not fully understood at the landscape level. Here we link the forest shade tolerance index to soil moisture in the North America using the U.S. and Quebec forest inventories. We report a significant decrease of shade tolerance index along the hydric–mesic–xeric soil transition in most of the area considered except three subtropical/tropical ecoregions of the Southeastern U.S. We conclude that droughts may alter forest succession, and in particular decrease the role of forest gap dynamics and dominance of the shade-tolerant species in mature forests.
Research Interests:
The Monod model is a classical microbiological model often used in environmental sciences, for example to evaluate biodegradation processes. The model describes microbial growth kinetics in batch culture experiments using three... more
The Monod model is a classical microbiological model often used in environmental sciences, for example to evaluate biodegradation processes. The model describes microbial growth kinetics in batch culture experiments using three parameters: the maximal specific growth rate, the saturation constant and the yield coefficient. However, identification of these parameter values from experimental data is a challenging problem. Recently, it was demonstrated theoretically that the application of optimal design theory in this model is an efficient method for both parameter value identification and economic use of experimental resources [Dette, H., Melas, V.B., Pepelyshev, A., Strigul, N., 2003. Efficient design of experiments in the Monod model. J. R. Stat. Soc. B 65 (Part 3), 725–742]. The purpose of this paper is to provide this method as a computational ''tool'' such that it can be used by practitioners without a strong mathematical and statistical background for the efficient design of experiments in the Monod model. The paper presents careful explanations of the principal theoretical concepts, and a simple algorithm for practical optimal design calculations.
Research Interests:
Understanding forest complexity and self-organization across multiple scales is essential for both ecology and natural resource management. In this paper, we develop a Markov chain approach for the modelling of forest stand dynamics. The... more
Understanding forest complexity and self-organization across multiple scales is essential for both ecology and natural resource management. In this paper, we develop a Markov chain approach for the modelling of forest stand dynamics. The aim of this work is to generalize the recently developed Perfect Plasticity Approximation (PPA) model for scaling of vegetation dynamics from individual level to the landscape level through the ecosystem hierarchical structure. Our basic assumption is that the forested ecosystem and disturbance regimes can be modelled on 3 hierarchical scales (levels): individual trees, forest stand (or patch, defined as a spatial unit about 0.5e1 ha of the same forest at one successional stage.) and landscape (collection of forest patches of different forest/soil types at different successional stages) levels. In our modelling approach the PPA model is an intermediate step for scaling from the individual level to the forest stand level (or patch level). In this paper we develop a Markov chain model for stage-structured dynamics of forest stands (patches). In order to determine the structure of the Markov chain model and estimate parameters, we analyze the patch-mosaic patterns of forest stands of the Lake States (MI, WI, and MN) recorded in the USDA FIA database as well as data for other US states and Canada. The distribution of macroscopic characteristics of a large collection of forest patches is considered as an estimate of the stationary distribution of the underlying Markov chain. The data demonstrates that this distribution is unimodal and skewed to the right. We identify the simplest Markov chain that produces such a distribution and estimate the upper bound of the probability of disaster for this Markov chain.
Research Interests: Statistics, Forestry, Applied Statistics, Biomass, Probabilistic Markov Modeling, and 13 moreEcology, Modeling and Simulation, Forest Ecology, Dynamics and Structure of Forest Ecosystems, Transition, Markov chains, Hidden Markov Models, Succession, Forest succession, Ecological Succession, Early Successional Forest, Forest Disturbances, and Forest Stand Dynamics
The acute toxicity of four different nanosized particulate materials (titanium dioxide, boron nanoparticles, and two types of aluminum nanoparticles (ALEX and L-ALEX)) were evaluated using two tests: the Microtox toxicity test and the... more
The acute toxicity of four different nanosized particulate materials (titanium dioxide, boron nanoparticles, and two types of aluminum nanoparticles (ALEX and L-ALEX)) were evaluated using two tests: the Microtox toxicity test and the acute toxicity test with Daphnia magna. The results were analyzed in order to calculate LD 50 at 24 and 48 h. It was found that titanium dioxide nanoparticles show a low level of toxicity, and LD 50 values cannot be calculated. Conversely, boron nanoparticles with EC 50 ranging from 56 to 66 mg L À1 , depending upon the age of the solution, can be classified as ''harmful'' to aquatic microorganisms (EC 50 in the range 10–100 mg L À1). We have also discussed possible mechanisms of nanoparticle toxicity and potential problems in ecotoxicological testing of nanomaterials. The studied nanomaterials can be ranked in the following order according to their Daphnia acute toxicity: boron nanoparticles>ALEX>L-ALEX> TiO 2 .
Research Interests:
One of the main problems when introducing beneficial microbes to the plant rhizosphere is that the plant growth promoting rhizobacteria (PGPR) do not survive or do not execute their specific function. The goal of our research was to... more
One of the main problems when introducing beneficial microbes to the plant rhizosphere is that the plant growth promoting rhizobacteria (PGPR) do not survive or do not execute their specific function. The goal of our research was to evaluate microbial inoculant survival in rhizospheres, using mathematical modeling and computer-based simulations. We tested several abiotic factors effects on PGPR survival: the availability of soluble organic compounds and molecular oxygen, and the concentration of mineral nitrogen in soil. The principal biotic factors considered were the direct and indirect interactions between PGPR and resident microorganisms, protozoan predation, and bacterial parasitism. A model system of four non-linear ordinary differential equations was developed to simulate the growth of PGPR populations in the rhizosphere. Simulation results indicated that the competition for limiting resources between the introduced population and the resident microorganisms was the most important factor determining PGPR survival. The most effective PGPR inoculation was expected in organic and mineral poor soils or stressed soils, when development of the resident microflora was inhibited. Another important factor for PGPR survival was compatibility between the composition of the host plant root exudates, and ability of the PGPR to utilize those compounds.
Research Interests:
A quantitative model is proposed to describe the population dynamics of associative nitrogen-fixing microorganisms in the plant rhizosphere as dependent on the rate of carbon substrate exudation by plant roots. By changing the values of... more
A quantitative model is proposed to describe the population dynamics of associative nitrogen-fixing
microorganisms in the plant rhizosphere as dependent on the rate of carbon substrate exudation by plant roots.
By changing the values of the basic model parameters, the effect of various factors on the behavior of two competing
populations of rhizosphere microorganisms can be studied.
microorganisms in the plant rhizosphere as dependent on the rate of carbon substrate exudation by plant roots.
By changing the values of the basic model parameters, the effect of various factors on the behavior of two competing
populations of rhizosphere microorganisms can be studied.
Research Interests:
Research Interests:
The perfect-plasticity approximation (PPA) is an analytically tractable model of forest dynamics, defined in terms of parameters for individual trees, including allometry, growth, and mortality. We estimated these parameters for the eight... more
The perfect-plasticity approximation (PPA) is an analytically tractable model of forest dynamics, defined in terms of parameters for individual trees, including allometry, growth, and mortality. We estimated these parameters for the eight most common species on each of four soil types in the US Lake states (Michigan, Wisconsin, and Minnesota) by using short-term (≤15-year) inventory data from individual trees. We implemented 100-year PPA simulations given these parameters and compared these predictions to chronosequences of stand development. Predictions for the timing and magnitude of basal area dynamics and ecological succession on each soil were accurate, and predictions for the diameter distribution of 100-year-old stands were correct in form and slope. For a given species, the PPA provides analytical metrics for early-successional performance (H20, height of a 20-year-old open-grown tree) and late-successional performance (Ẑ*, equilibrium canopy height in monoculture). These metrics predicted which species were early or late successional on each soil type. Decomposing Ẑ* showed that (i) succession is driven both by superior understory performance and superior canopy performance of late-successional species, and (ii) performance differences primarily reflect differences in mortality rather than growth. The predicted late-successional dominants matched chronosequences on xeromesic (Quercus rubra) and mesic (codominance by Acer rubrum and Acer saccharum) soil. On hydromesic and hydric soils, the literature reports that the current dominant species in old stands (Thuja occidentalis) is now failing to regenerate. Consistent with this, the PPA predicted that, on these soils, stands are now succeeding to dominance by other late-successional species (e.g., Fraxinus nigra, A. rubrum).
Research Interests:
Imitation is one of the central processes underlying learning. Although the mechanisms of imitation at the individual level have received considerable attention, the population effects of imitative behavior have scarcely been... more
Imitation is one of the central processes underlying learning. Although the mechanisms of imitation at the individual level have received considerable attention, the population effects of imitative behavior have scarcely been investigated. In this paper I address the problem of self-organization at the population level emerging from imitative behavior between individuals. The model considered is a modification of that developed by Durrett and Levin [Durrett, R., Levin, S.A., 2005. Can stable social groups be maintained by homophilous imitation alone? J. Econ. Behav. Organ. 57, 267–286] in investigation of the coexistence of social groups. I modified the previous model in order to approach it in describing not only human societies but also animal populations with simpler cultures. In contrast with the other studies, I do not assume any payoffs related to imitation behavior and the existence of social rank. Individuals are assumed to be of equal rank and to accept opinions of others in proportion to their similarity (homophilous imitation). The symmetrical structure of interactions induces random drift and development of stable self-organized social groups in both homogeneous and spatially distributed societies. This type of self-organization may be widely distributed in natural systems, where imitative behavior takes place. In particular, it can be involved in origins of dialects and ring species.
Research Interests:
Research Interests: Environmental Engineering, Chemical Engineering, Pharmacology, Environmental Science, Health Sciences, and 23 morePharmacy, Environmental Law, Environmental Toxicology, Ecotoxicology, Toxicology, Occupational Health & Safety, Aquatic Toxicology, Air pollution, Air Pollution and Health Effects, Tungsten and Its Alloys, Removal Of Heavy Metals In Contaminated Soils, Public Health, Water Pollution, Earth and Environmental Sciences, Hazardous Waste Management, Environmental regulations, Heavy Metal Pollution, former Soviet Union, Tungsten, Tungstate, Sodium Polytungstate, Tungsten Speciation, and Wolfram Toxicity
Individual-based forest simulators, such as TASS and SORTIE, are spatial stochastic processes that predict properties of populations and communities by simulating the fate of every plant throughout its life cycle. Although they are used... more
Individual-based forest simulators, such as TASS and SORTIE, are spatial stochastic processes that predict properties of populations and communities by simulating the fate of every plant throughout its life cycle. Although they are used for forest management and are able to predict dynamics of real forests, they are also analytically intractable, which limits their usefulness to basic scientists. We have developed a new spatial individual-based forest model that includes a perfect plasticity formulation for crown shape. Its structure allows us to derive an accurate approximation for the individual-based model that predicts mean densities and size structures using the same parameter values and functional forms, and also it is analytically tractable. The approximation is represented by a system of von Foerster partial differential equations coupled with an integral equation that we call the perfect plasticity approximation (PPA). We have derived a series of analytical results including equilibrium abundances for trees of different crown shapes, stability conditions, transient behaviors, such as the constant yield law and self-thinning exponents, and two species coexistence conditions.
Research Interests:
In this paper the problem of designing experiments for the Monod model, which is frequently used in microbiology, is studied. The model is defined implicitly by a differential equation and has numerous applications in microbial growth... more
In this paper the problem of designing experiments for the Monod model, which is frequently used in microbiology, is studied. The model is defined implicitly by a differential equation and has numerous applications in microbial growth kinetics, environmental research, pharmacokinetics, and plant physiology. The designs presented so far in the literature are local optimal designs, which depend sensitively on a preliminary guess of the unknown parameters, and are for this reason in many cases not robust with respect to their misspecification. Uniform designs and maximin optimal designs are considered as a strategy to obtain robust and efficient designs for parameter estimation. In particular, standardized maximin D-and E-optimal designs are determined and compared with uniform designs, which are usually applied in these microbiological models. It is demonstrated that maximin optimal designs are substantially more efficient than uniform designs. Parameter variances can be decreased by a factor of two by simply sampling at optimal times during the experiment. Moreover, the maximin optimal designs usually provide the possibility for the experimenter to check the model assumptions, because they have more support points than parameters in the Monod model.
Research Interests:
Estimation and experimental design in a non-linear regression model that is used in microbiology are studied. The Monod model is defined implicitly by a differential equation and has numerous applications in microbial growth kinetics,... more
Estimation and experimental design in a non-linear regression model that is used in microbiology are studied. The Monod model is defined implicitly by a differential equation and has numerous applications in microbial growth kinetics, water research, pharmacokinetics and plant physiology. It is proved that least squares estimates are asymptotically unbiased and normally distributed. The asymptotic covariance matrix of the estimator is the basis for the construction of efficient designs of experiments. In particular locally D-, E-and c-optimal designs are determined and their properties are studied theoretically and by simulation. If certain intervals for the non-linear parameters can be specified, locally optimal designs can be constructed which are robust with respect to a misspecification of the initial parameters and which allow efficient parameter estimation. Parameter variances can be decreased by a factor of 2 by simply sampling at optimal times during the experiment.
Research Interests: Microbiology, Design of Experiments, Modeling and Simulation, Microbial biotechnology, Mathematical Modelling, and 12 moreFood Microbiology, Microbial Biotechnology, Biodegradation, Regression, Regression Analysis, Kinetics of Biodegradation/bioremediation, Food and Industrial Microbiology, Nonlinear Least Square Technique, Growth Curve, Optimal Design of Experiments, Monod model, and Microbial Growth
Tungsten is a widely used transition metal for which very limited information on environmental and toxicological effects is available. Of particular interest is the lack of information linking tungsten speciation and environmental... more
Tungsten is a widely used transition metal for which very limited information on environmental and toxicological effects is available. Of particular interest is the lack of information linking tungsten speciation and environmental effects. Tungsten anions may polymerize (depending upon concentration, pH, and aquatic geochemistry) in aquatic and soil systems. However, to this date, of all soluble tungstate species only monotungstates have been scrutinized to a fair extent in toxicological studies. The objective of this work is a comparative assessment of the acute toxicity of monotungstates (sodium tungstate, Na 2 WO 4) and polytungstates (sodium metatungstate, 3Na 2 WO 4 Á 9WO 3) to Poecilia reticulate. The experiments have been performed according to the OEDC protocols 203 and 204. LD50 values for 1– 14 days show that sodium metatungstate is significantly more toxic to fish than sodium tungstate. Based on LD50 (0.86–3.88 g L À 1 or 4.67–21.1 Â10 À 3 mol Na 2 WO 4 L À 1), sodium tungstate may be classified as a chemical of low toxicity to fish. Sodium metatungstate caused similar fish mortality to sodium tungstate when it was introduced in 55–80 times lower concentrations (in terms of mol L À 1) than sodium tungstate. LD50 values for sodium metatungstate range from 0.13 to 0.85 g W L À 1 or 5.69 to 38.71 Â10 À 5 mol 3Na 2 WO 4 Á 9WO 3 L À 1. Based on these values sodium metatungstate can be classified as a moderate toxic agent to fish.
Research Interests:
Tungsten is a widely used transition metal that has not been thoroughly investigated with regards to its ecotoxicological effects. Tungsten anions polymerize in environmental systems as well as under physiological conditions in living... more
Tungsten is a widely used transition metal that has not been thoroughly investigated with regards to its ecotoxicological effects. Tungsten anions polymerize in environmental systems as well as under physiological conditions in living organisms. These polymerization/condensation reactions result in the development of several types of stable polyoxoanions. Certain chemical properties (in particular redox and acidic properties) differentiate these polyanions from monotungstates. However, our current state of knowledge on tungsten toxicology, biological and environmental effects is based entirely on experiments where monotungstates were used and assumed by the authors to be the form of tungsten that was present and that produced the observed effect. Recent discoveries indicate that tungsten speciation may be important to ecotoxicology. New results obtained by different research groups demonstrate that polytungstates develop and persist in environmental systems, and that polyox-otungstates are much more toxic than monotungstates. This paper reviews the available toxicological information from the standpoint of tungsten speciation and identifies knowledge gaps and pertinent future research directions.