Potato (Solanum tuberosum L.) is one of the most important vegetable crops across world and India is second largest producer of this crop across the world. Early blight disease has been the most serious threat to world‟s potato... more
Potato (Solanum tuberosum L.) is one of the most important vegetable crops across world and India is second largest producer of this crop across the world. Early blight disease has been the most serious threat to world‟s potato production, resulting in 80-100 % yield loss. The causal agent of early blight is fungi, Alternaria solani. The present investigation was carried out to evaluate the efficacy of mycogenic silver nanoparticles (AgNPs) and zinc oxide nanoparticles (ZNOPs) as antifungal agents against A. solani. The nanoparticles were synthesized biologically by using Aspergillus flavus biomass and characterization was done by UV-Vis Spectroscopy, Field Emission Scanning Electron Microscopy (FESEM), Energy Dispersive X-Ray (EDX), Dynamic Light Scattering (DLS), Fourier Transform Infra Red (FTIR) and inductively coupled plasma mass spectrometry (ICPMS). The inhibition percentage of A. solani caused by nanoparticle treatments was established in vitro. Field experiment was conducted to compare the efficiency of nanoparticles and chemical fungicide at the parameters of disease severity, tuber number and tuber weight. The data were analyzed by SPSS for descriptive statistics and analysis of variance (ANOVA) including least significance difference (LSD) and results were found to be significant for different parameters at 0.05 significance levels. It may be concluded by the experiment that AgNPs and ZONPs may be proved to be potential fungicides in near future and it is an excellent alternative to chemical fungicides.
Research Interests:
Abstract Business-to-business firms have traditionally encountered disruptions, but the scale of the COVID-19 pandemic was extraordinary as it interrupted global supply chains by causing unprecedented shocks to supply and demand. Firms... more
Abstract Business-to-business firms have traditionally encountered disruptions, but the scale of the COVID-19 pandemic was extraordinary as it interrupted global supply chains by causing unprecedented shocks to supply and demand. Firms experienced extraordinary pressure and struggled to minimize the immediate and long-term impact of supply chains disruptions. Applying chaos theory, this study employs a single-case method to understand the disruptions to the business-to-business oil and gas supply chain. We make three major contributions. First, we examine firm decision-making during significant disruptions. Second, we use chaos theory to better understand the decision-making process. Finally, we develop a framework to explicate the decision-making process and provide guidelines for decision-making during disruptions. Our findings provide theoretical insights and have important implications for practitioners addressing supply chain disruptions during crises.
Research Interests:
Research Interests:
This paper presents a research work focussed on the identification of faults on the distribution feeder supported by Stockwell transform based summing of absolute values and median features using the voltage signals. A fault index is... more
This paper presents a research work focussed on the identification of faults on the distribution feeder supported by Stockwell transform based summing of absolute values and median features using the voltage signals. A fault index is proposed which is obtained by the multiplication of H-index (obtained summation of absolute values S-matrix evaluated by ST supported decomposition of voltage) and VS-index (obtained median of absolute values S-matrix evaluated by ST supported decomposition of voltage). Classification of faults is achieved using decision rules. Investigated faults include phase to ground, fault between two phases, two phases to ground fault and fault involving all three phases and ground. Performance of algorithm is tested on high fault impedance and fault incidence angle. Proposed study is performed using MATLAB software in Simulink environment.
Research Interests:
Research Interests:
Frequency deviation is a one of major technical issue of a interconnected power system. In this paper an optimized Proportional-Integral-Derivative (PID) controller ios proposed for controlling the frequency deviation. To optimize the... more
Frequency deviation is a one of major technical issue of a interconnected power system. In this paper an optimized Proportional-Integral-Derivative (PID) controller ios proposed for controlling the frequency deviation. To optimize the gain values of controller, the Adaptive Particle Swarm Optimization (APSO) algorithm is utilized. Tuning of controllers is done in order to get the gain values or controller parameters such that the desired frequency and power interchange with interconnected systems. Controllers must possess the property of being sensitive against deviations in frequency. Tuning of proposed controller based on APSO algorithm is justified by making a comparison with PSO optimized PID and Conventional Ziegler– Nichols tuned PID controller.
Research Interests:
Background: Breastmilk is the natural first food for babies which provides all the energy and nutrients that the infant needs for the first few months of life. More than two thirds of the 2.4 million child deaths occurring each year in... more
Background: Breastmilk is the natural first food for babies which provides all the energy and nutrients that the infant needs for the first few months of life. More than two thirds of the 2.4 million child deaths occurring each year in India are related to inappropriate infant feeding practices. Initiation of breastfeeding within 1 hour of birth in central Indian states is among the lowest. The situation in central Indian states especially Uttar Pradesh is worse than the rest of India which is usually attributed to prevalent socio-economic and cultural factors.Methods: A cross-sectional descriptive study that was conducted among 144 mothers visiting a tertiary care hospital in Lucknow, Uttar Pradesh, India over a period of nine months using a questionnaire-based interview. Results: The study found that majority of subjects has good knowledge about breastfeeding. 92.4% mothers reported knowledge of putting the baby on the breast within an hour of birth. 65% had the correct breastfee...
Research Interests:
Abstract In the recent time, aqueous polymer quenchants are gaining importance in the steel heat treatment processes over conventional quenchants. It has been observed that desirable microstructure and mechanical properties can be... more
Abstract In the recent time, aqueous polymer quenchants are gaining importance in the steel heat treatment processes over conventional quenchants. It has been observed that desirable microstructure and mechanical properties can be achieved by proper adjustment of the quench parameters in the polymeric media. Reduction of distortion and cracking of heat treated steel has also been reported. However, the effect of this comparatively new technique of heat treatment on the tribologicalbehavior of steel has not been reported to a greater extent. In the present experimental study the effect of aqueous PEG-400 (poly ethylene glycol) solution as a quenching medium on medium carbon steel has been studied followed by the study of friction and wear. Multi tribotester ‘TR-25’ (DUCOM) has been utilized for this purpose. This paper also highlights the different applications of the new generation polymer quenchants and various critical quenching system parameters that need to be considered during the design stage of the quenching system for the new generation polymer quenchants. The results have been discussed along with necessary figures
Research Interests:
Research Interests:
Research Interests:
Research Interests:
Four (1, 2, 4 and 6) synthetic quaternary ammonium derivatives of pyranochromenones and (coumarinyloxy)acetamides were synthesized and investigated for their antimicrobial efficacy on MRSA (Methicillin-resistant Staphylococcus aureus),... more
Four (1, 2, 4 and 6) synthetic quaternary ammonium derivatives of pyranochromenones and (coumarinyloxy)acetamides were synthesized and investigated for their antimicrobial efficacy on MRSA (Methicillin-resistant Staphylococcus aureus), and multi-drug resistant Pseudomonas aeruginosa, Salmonella enteritidis and Mycobacterium tuberculosis H37Rv strain. One of the four compounds screened i.e. N,N,N-triethyl-10-((4,8,8-trimethyl-2-oxo-2,6,7,8-tetrahydropyrano[3,2-g]chromen-10-yl)oxy)decan-1-aminium bromide (1), demonstrated significant activity against S. aureus, P. aeruginosa and M. tuberculosis with MIC value of 16, 35, and 15.62 µg/ml respectively. The cytotoxicity evaluation of compound 1 on A549 cell lines showed it to be a safe antimicrobial molecule, TEM study suggested that the compound led to the rupture of the bacterial cell walls.
Research Interests:
Research Interests:
Research Interests:
Research Interests:
This study demonstrates the therapeutic potential of silver nanoparticles (AgNPs), which were biosynthesized using the extracts of Citrus maxima plant. Characterization through UV-Vis spectrophotometry, Dynamic Light Scattering (DLS),... more
This study demonstrates the therapeutic potential of silver nanoparticles (AgNPs), which were biosynthesized using the extracts of Citrus maxima plant. Characterization through UV-Vis spectrophotometry, Dynamic Light Scattering (DLS), Fourier Transform Infrared spectroscopy (FTIR), X-ray Diffraction (XRD) and Transmission Electron Microscopy (TEM) confirmed the formation of AgNps in nano-size range. These nanoparticles exhibited enhanced antioxidative activity and showed commendable antimicrobial activity against wide range of microbes including multi-drug resistant bacteria that were later confirmed by TEM. These particles exhibited minimal toxicity when cytotoxicity study was performed on normal human lung fibroblast cell line as well as human red blood cells. It was quite noteworthy that these particles showed remarkable cytotoxicity on human fibrosarcoma and mouse melanoma cell line (B16-F10). Additionally, the apoptotic topographies of B16-F10 cells treated with AgNps were conf...
Research Interests:
Alzheimer's disease (AD), a neurodegenerative disorder, is a serious medical issue worldwide with drastic social consequences. Inhibition of cholinesterase is one of the rational and effective approaches to retard the symptoms of AD... more
Alzheimer's disease (AD), a neurodegenerative disorder, is a serious medical issue worldwide with drastic social consequences. Inhibition of cholinesterase is one of the rational and effective approaches to retard the symptoms of AD and, hence, consistent efforts are being made to develop efficient anti-cholinesterase agents. In pursuit of this, a series of 19 acetamide derivatives of chromen-2-ones were synthesized and evaluated for their acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibitory potential. All the synthesized compounds exhibited significant anti-AChE and anti-BChE activity, with IC50 values in the range of 0.24-10.19 μM and 0.64-30.08 μM, respectively, using donepezil hydrochloride as the standard. Out of 19 compounds screened, 3 compounds, viz. 22, 40, and 43, caused 50% inhibition of AChE at 0.24, 0.25, and 0.25 μM, respectively. A kinetic study revealed them to be mixed-type inhibitors, binding with both the CAS and PAS sites of AChE. The above...
Research Interests: Chemistry, Medicine, Humans, Blood brain barrier, Animals, and 13 moreAcetylcholinesterase, Cholinesterase inhibitors, Neuroblastoma, Chromones, Erythrocytes, Alzheimer Disease, Minimum inhibitory concentration, Piperidines, Hemolysis, Butyrylcholinesterase, Indans, acetamide, and Pharmacology and pharmaceutical sciences
Research Interests:
Here, we have investigated in vitro antimicrobial efficacy of a quaternized cationic polymer, poly[bis(2-chloroethyl)ether- alt-1,3-bis[3-(dimethylamino)propyl]urea] (polyquaternium-2), against gram-positive as well as gram-negative... more
Here, we have investigated in vitro antimicrobial efficacy of a quaternized cationic polymer, poly[bis(2-chloroethyl)ether- alt-1,3-bis[3-(dimethylamino)propyl]urea] (polyquaternium-2), against gram-positive as well as gram-negative bacteria along with several multi-drug-resistant bacterial strains. The antimicrobial efficacy of this polymer was first tested against some clinical pathogens followed by microorganisms isolated from acne lesions. Interestingly, polyquaternium-2 exhibited significant antimicrobial activity against methicillin-resistant Staphylococcus aureus, for which very limited drugs are available. Most importantly, the polymer displayed low haemolytic activity and non-toxic behaviour against mammalian cells. The results showed the promising potential of the projected polymer to be utilized as an antibacterial agent for various biomedical applications.
Research Interests:
Research Interests:
Research Interests:
Research Interests:
Abstract Purpose To introduce macro-behavioral perspective for understanding pro-sustainability actions from the perspective of various stakeholders. Methodology/approach Recent research on sustainability, behavior change, and... more
Abstract Purpose To introduce macro-behavioral perspective for understanding pro-sustainability actions from the perspective of various stakeholders. Methodology/approach Recent research on sustainability, behavior change, and environmentalism is reviewed to conceptualize a comprehensive macromarketing framework to spawn and diffuse pro-sustainability behaviors. Findings Provides a comprehensive macromarketing framework that not only explains the behavioral factors from firm’s perspective but also explains these factors from the perspective of various stakeholders who are part of the entire value chain. Research limitations/implications The paper adds to the literature on pro-sustainability behaviors by providing a research framework from macro-marketing point of view. Practical implications As practical insight, the paper provides some important guidance in terms of better understanding on firm-specific and individual-specific actions which may help in progressing toward sustainability. Originality/value The paper integrates past observations on behavioral aspect of sustainability and develops an important framework to understand pro-sustainability actions.
Research Interests:
This study explores the expenditure pattern on different commodity groups such as food, fuel and lighting, clothing and other items across Indian households. The study also explores the variables apart from income which affect the... more
This study explores the expenditure pattern on different commodity groups such as food, fuel and lighting, clothing and other items across Indian households. The study also explores the variables apart from income which affect the expenditure on commodity groups across rural and urban population in India. Estimates made for expenditure elasticity taking into account the regional differences in India across rural and urban settings provide some important implications for the marketers on issues like income-based segmentation as well as consumption pattern on commodities. This study also has policy implications with insights on social welfare programs depending upon the nature of expenditure elasticity for a particular commodity group linked with income of the household. The nature and magnitude of the elasticity also provides a policy tool for devising the tax structure based on expenditure towards necessity or luxury goods with respect to the income level of the household.