Donatien KONE

Costus spectabilis is a rhizomatous geophyte used by traditional medicine to treat internal and external wounds, coughs, inflammation, arthritis, rheumatism, fever, maternal and neonatal infections. It is also recommended for its laxative, purgative, diuretic and ichthyotoxic properties. A phytochemical study of the leaves of Costus spectabilis, revealed the presence of flavonoids, alkaloids, sterols and triterpenes, coumarins, reducing compounds, oses and holosides. The combination of chromatographic (CC and TLC), 1D NMR spectral (1H, 13C), 2D (COZY and HMQC) and spectrometric (ESI-MS positive mode) techniques allowed the isolation and identification of kaempferol 3- O- (6- O- (α-L-rhamnosyl) β-D-glucoside or nicotiflorin of the methanol extract of the leaves of Costus spectabilis.

Une etude phytochimique realisee sur les alcaloides des feuilles de Vepris heterophylla a fourni deux composes qui sont: 4,6,7-trimethoxyfuro[2,3-b]quinoleine (kokusaginine) et 1-(4,7-dimethoxyfuro[2,3-b]quinolein-6-yloxy)-3-methylbutan-2,3-diol (montrifoline) deux alcaloides furoquinoleiques caracteristiques des Rutaceae dont les structures ont ete elucidees par les techniques spectrales de RMN et SM. A notre connaissance, c'est la premiere fois que la presence de la montrifoline soit signalee dans Vepris heterophylla.

This study evaluates the levels of total polyphenolic compounds in three Malian medicinal plants and determines their antioxidant potential. Quantitative and qualitative analysis of polyphenolics contained in plants extracts were carried out by RP-C18 RP–HPLC using UV detector. The antioxidant activity was determined by three tests. They are phosphomolybdenum, DPPH (2,2-diphenyl-1 picrylhydrazyl) and ABTS [2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic)] tests. The total phenolic and the total flavonoid contents varied from 200 to 7600 mg 100 g−1dry weight (dw), expressed as gallic acid equivalents and from 680 to 12 300 mg 100 g−1dw expressed as catechin equivalents, respectively. The total anthocyanin concentrations expressed as cyanin-3-glycoside equivalent varied from 1670 to 28 388 mg 100 g−1dw. The antioxidant capacity was measured by determining concentration of a polyphenolic (in mg ml−1) required to quench the free radicals by 50% (IC50) and expressed as vitamin C equival...