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We sought to evaluate if patients with proximal critical circumflex (CX) lesions did better with single SV-CABG on the best obtuse marginal (OM), or with sequential SV-CABG on two OM branches. Ninety patients were prospectively randomised... more
We sought to evaluate if patients with proximal critical circumflex (CX) lesions did better with single SV-CABG on the best obtuse marginal (OM), or with sequential SV-CABG on two OM branches. Ninety patients were prospectively randomised to single SV-CABG on the best OM (sSV-CABG-45 patients; Group A) or to sequential SV-CABG on 2 OM (seqSV-CABG 45 patients; Group B). Transit-time flowmetry (TTF), and graft flow reserve were evaluated. Recurrent angina, acute myocardial infarction, readmission for coronary reintervention were defined "treatment failure" during follow-up. SeqSV-CABG showed better intraoperative maximum (119.1+/-57.5 ml/min vs. sSV-CABG 62.4+/-29.6; p=0.001), mean (56.3+/-31.5 ml/min vs. 30.8+/-12.8; p=0.0001), minimum flow (22.8+/-9.2 ml/min vs. 11.8+/-8.9; p=0.001) and P.I. (0.71+/-0.4 vs.1.46+/-0.9; p=0.006). Graft flow reserve also proved to be higher (95.4+/-29.7 ml/min mean flow vs. sSV-CABG 42.3+/-15.2 ml/min mean flow; p=0.0001; flow reserve 1.72+/-0.99 vs 1.32+/-1.09; p=0.001) as well as freedom from treatment failure (97.5+/-0.5% vs 88.7+/-0.4%; p=0.05). SeqSV-CABG showed higher TTF flows, with no incremental risk for perioperative morbidity. Higher flows and graft flow reserve may allow lower treatment failure at mid-term follow-up.
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Preoperative intra-aortic balloon pumping (IABP) improves the results of complex coronary surgery. However, its insertion may be harmful or contraindicated in cases of severe and diffuse atherosclerosis of the descending aorta and... more
Preoperative intra-aortic balloon pumping (IABP) improves the results of complex coronary surgery. However, its insertion may be harmful or contraindicated in cases of severe and diffuse atherosclerosis of the descending aorta and peripheral arteries. We sought to evaluate the efficacy and safety of transbrachial insertion of the new 7.5-Fr IABP to support a severely ill patient with eggshell distal aorta and femoro-iliac arteries undergoing coronary artery bypass grafting (CABG). Case report. An 18-bed adult cardiac surgery unit at a university hospital. A 68-yr-old man with ongoing unstable angina, left main disease, and eggshell calcification in the abdominal aorta and iliaco-femoral arteries, needing IABP for CABG. Percutaneous sheathless right transbrachial insertion of 7.5-Fr IABP, followed by CABG. Fluoroscopy and chest radiograph were used to confirm the exact position of the IABP, in the preoperative and postoperative time, respectively. A digital pulse oximeter was applied to monitor distal perfusion. Anticoagulation consisted of nadroparin 4000 IU daily until the second postoperative day, followed by 150 mg of aspirin daily thereafter. Transbrachial IABP support allowed uneventful CABG and postoperative course, without IABP-related complications. Pulse oximetry demonstrated constant good values, the radial artery pulse was always present, and the hand appeared constantly warm. IABP was withdrawn 20 hrs following surgery, and the patient was discharged home on the ninth postoperative day. The miniaturization of IABP, with the recent introduction of a 7.5-Fr balloon catheter, opens the door for the safe, effective transbrachial method of insertion in patients with severe peripheral atherosclerosis.
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Research Interests: Ecology, Conservation planning, Biodiversity Conservation, Spatial autocorrelation, Habitat Heterogeneity, and 13 moreGeneralised Linear Mixed Model, Species Diversity, Species Richness, Multiple Linear Regression, Prediction Model, Spatial Pattern, Geographic Information, Model Based Approach, Ecological Applications, Landscape Heterogeneity, Conservation strategies, ENVIRONMENTAL SCIENCE AND MANAGEMENT, and Generic model
Research Interests: Treatment Outcome, Lung Function, Prospective studies, Humans, Female, and 17 moreMale, RSC, Lung, Map, Clinical Sciences, Aged, Middle Aged, Myocardial Infarction, Oxygen, Vital Capacity, SCR, Chronic obstructive pulmonary disease, Hospital Mortality, Coronary artery bypass surgery, Pulsatile Flow, Pulmonary circulation, and Cardiopulmonary bypass
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Research Interests: Electrocardiography, Multivariate Analysis, Prospective studies, Humans, Female, and 13 moreMale, Clinical Sciences, Aged, Myocardial Infarction, Time Factors, Prognosis, Hospital Mortality, Coronary artery bypass surgery, Myocardial Protection, Troponin I, Unstable Angina, Heart Diseases, and Cardiopulmonary bypass
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We investigated wolf Canis lupus Linnaeus, 1758 food habits in central Italy by examining stomach and/or intestine contents of 59 individuals. Road accident and illegal kills were main causes of the wolves' death. Ungulates... more
We investigated wolf Canis lupus Linnaeus, 1758 food habits in central Italy by examining stomach and/or intestine contents of 59 individuals. Road accident and illegal kills were main causes of the wolves' death. Ungulates represented the bulk of the diet (55% in frequency), and ...