Gregorio Quintero Beuló

To know the surgical-pathologic correlation to assess the state of the edges in wide local excisions of breast cancer in clinical stages. retrospective and descriptive study, conducted in Breast Tumors Unit from Oncology Service of the General Hospital of Mexico, in the period from January 2009 to December 2011, with follow-up in December2012. Were included patients with breast cancer in early clinical stages, subject wide local excisions histopalogic report of a second surgery. From wide local excisions, 119 (28.5%) were due to breast cancer and included. Positive margins after initial surgery were diagnosed in 63 patients (52.9%). The residual tumor found in the second surgery was 39.7%. The variables associated with the presence of positive margins and statistically significant (p≤ 0.05) were: multicentricity, tumor size clinical and pathological, histological subtypes, and tumor grade. The age and clinical stage were not statistically significant. The variables associated with t...

Objetivo: conocer la correlacion quirurgico-patologica que permita evaluar el estado de los bordes en las escisiones locales amplias por cancer mamario en estadios clinicos tempranos. Material y metodo: estudio descriptivo y retrospectivo efectuado en la Unidad de Tumores Mamarios del servicio de Oncologia del Hospital General de Mexico, de enero 2009 a diciembre 2011, con seguimiento hasta diciembre 2012. Se incluyeron pacientes con cancer mamario en etapas clinicas tempranas a quienes se hicieron escisiones locales amplias con reporte histopatologico de bordes positivos y segunda cirugia. Resultados: de 418 escisiones locales amplias, 119 (28.5%) fueron por cancer mamario e incluidas. Los margenes positivos despues de la cirugia inicial se diagnosticaron en 63 pacientes (52.9%). En 39.7% de los casos se encontro un tumor residual en la segunda cirugia. Las variables asociadas con margenes positivos con significacion estadistica (p≤0.05) fueron: multicentricidad, tamano del tumor c...

Neoadjuvant Chemotherapy (NACT) is the standard of care for locally advanced breast tumors and may be administered in some operable tumors, although its use has not been widely adopted in all settings. In Mexico, 52% of breast cancer patients receive NACT [1]. Many factors contribute to less use of NACT when compared to other countries, including the lack of assessment and treatment decision-making by a Multidisciplinary Team (MDT), unavailability of NACT therapeutics, and readiness of a complete histopathological report. The aim of this review is to describe prognostic factors and provide evidence-based recommendations for both the optimal use of NACT and collaborative treatment decision making in our local setting to improve patient outcomes.