Marielle Di Domenico

OBJECTIVES: This study evaluated the effectiveness of hydrogen peroxide (H2O2) as mouthwash and nasal spray on symptom relief in coronavirus disease 2019 (COVID-19) patients.METHODS: Patients positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), who were treated in a hospital or at home, and patients’ family members (not positive for SARS-CoV-2), were randomized into 2 groups: experimental (1% H2O2 for gargling, 0.5% H2O2 for nasal wash), and control. Patients gargled the solution 3 times a day, and applied the nasal spray twice a day, for a 7-day period. Family members received the same treatment as the treated COVID-19 patient. The researchers contacted patients every 2 days over an 8-day period. An average post-treatment interval of 8 days passed before testing family members.RESULTS: The most frequent symptoms on day 0 were cough, loss of taste, and hyposmia; there were no significant differences between groups, independent of the period. The symptom of dysp...

OBJECTIVES: To evaluate the effectiveness of hydrogen peroxide (H2O2) in the form of mouthwash and nasal spray as an auxiliary treatment for coronavirus disease 2019 (COVID-19).METHODS: Forty hospitalized patients who tested positive for severe acute respiratory syndrome coronavirus 2 using a reverse-transcription polymerase chain reaction test were evaluated. They were randomly divided into an experimental group (n= 20; gargling with 1.0% H2O2 and nasal wash with 0.5% H2O2) or a control group (n= 20). The solutions were used for 7 days and the patients were monitored every 2 days, for a total of 8 days. At check-ups, patients were asked about their symptoms and possible adverse effects of the solutions. The presence and severity (mild, moderate, or severe) of symptoms were recorded. Data were compared using the Student test and the Fisher exact test (α= 0.05).RESULTS: There was no significant difference between the 2 groups in the length of hospital stay (p= 0.65). The most frequen...

ObjectiveTo evaluate the bond strength of a polymer‐infiltrated ceramic‐network (PICN) material and to composite repair after different surface treatments.Materials and MethodsEighteen blocks of the PICN material were obtained from CAD/CAM blocks, aged and randomly divided into 2 groups: 5% hydrofluoric acid (HF) or sandblasting with aluminum oxide particles (SAND). For each condition, three treatments were tested: silane (Sil), silane‐containing adhesive (Ad), or silane + silane‐containing adhesive (SilAd). The treated PICN surfaces were restored with composite resin. The microtensile bond strength test was performed in a universal testing machine, and data (MPa) were compared with two‐way Analysis of variance (anova) and Tukey (α = 0.05). Roughness (Ra) and contact angle (CA) were obtained after HF and SAND conditions.ResultsThe greatest bond strength values were obtained for the groups Sil and SilAd, for both HF and SAND pretreatments. The Ra values of SAND were statistically gre...

This study evaluated the effect of clinical and patient-related factors on marginal bone loss. The sample was composed of individuals who were treated at two dental schools in southern Brazil. The variables evaluated were divided into individual (age, sex, diabetes, hypertension and antihypertensive use), and implant levels (arch, position, brand, protection, torque, time). After implant installation and following the second stage, periapical radiographs were obtained to measure the distance between the peri-implant bone crest and implant platform. Measurements were performed using ImageJ software. Data were analyzed using linear and Poisson multilevel regression. Fifty-eight patients with 113 implants were evaluated. The mean marginal bone loss was 0.45 ± 0.48 mm. Considering the linear multivariate model, age, diabetes, torque and time between surgery and reopening were found to be significant (p < 0.05). In the dichotomous model (bone loss <0.2 mm and ≥0.2 mm), only high to...