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ÖZET Oral kanserler KBB hekiminin sık karşılaştığı kanserlerdendir. Morbidite ve mortalite açısından önemli bir hastalık grubudur. Bu kanserlerin dünyada yapılan çalışmalarda, cinsiyet, yaş ve lokalizasyon dağılımı açısından farklılıklar... more
ÖZET Oral kanserler KBB hekiminin sık karşılaştığı kanserlerdendir. Morbidite ve mortalite açısından önemli bir hastalık grubudur. Bu kanserlerin dünyada yapılan çalışmalarda, cinsiyet, yaş ve lokalizasyon dağılımı açısından farklılıklar gösterdiği izlenmiştir. Bu çalışmada 231 olgu retrospektif ...
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Background The clinical definition of allergic rhinitis (AR) is difficult to use in epidemiological settings of large populations where it is impossible to obtain the laboratory evidence of each immune response. However, the... more
Background The clinical definition of allergic rhinitis (AR) is difficult to use in epidemiological settings of large populations where it is impossible to obtain the laboratory evidence of each immune response. However, the standardization of the definition of AR in epidemiological studies is of crucial importance. This study was designed to estimate the prevalence of AR in an adult general population with respect to seven distinct geographical regions in Turkey. Methods Individuals were evaluated with the Score for Allergic Rhinitis (SFAR) questionnaire for a national cross-sectional study. The Turkish version of the SFAR questionnaire was tested for clarity and sensitivity in a small sample of the general population. Results Among the 3967 interviewed subjects, the overall prevalence of AR was 29.6%, with regional variations (from 21.0% in the southeastern Anatolia region to 36.1% in the Marmara region). The prevalence was higher in women and in urban area of residence. Conclusio...
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The aim of this study was to investigate the neurovascular structures of the cavernous sinus with the endonasal endoscopic transpterygoid approach on fresh human cadavers. Additionally, the course of internal carotid artery (ICA) and... more
The aim of this study was to investigate the neurovascular structures of the cavernous sinus with the endonasal endoscopic transpterygoid approach on fresh human cadavers. Additionally, the course of internal carotid artery (ICA) and relevant anatomy was thoroughly investigated to refine the anatomical landmarks, exposure difficulties, potential complications, and limitations using the endonasal endoscopic technique. This study was carried out at an otolaryngology department of a tertiary medical center between June 2014 and June 2015. The surgical dissection was performed on 10 fresh human cadaver specimens using paranasal sinus and skull base endoscopic instruments. Cavernous sinuses and parasellar area were explored via an endoscopic endonasal transpterygoid approach. Dehiscence was present in 5 (25%) cavernous ICAs. Projection of the cavernous ICA on the whole lateral sphenoid wall was prominent in 6 (%30) sphenoid sinuses. Anterior curve was prominent in 12 (60%) cavernous ICAs...
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The aim of this study was to investigate the neurovascular structures and their relevant anatomy with the endonasal endoscopic transpterygoid approach on fresh human cadavers. In addition, the relationship between the vidian nerve, ICA... more
The aim of this study was to investigate the neurovascular structures and their relevant anatomy with the endonasal endoscopic transpterygoid approach on fresh human cadavers. In addition, the relationship between the vidian nerve, ICA and surrounding structures were investigated METHODS: This study was carried out at an otolaryngology department of a tertiary medical center between June 2014 and June 2015. Ten fresh human cadavers were included in this study. Pterygopalatine fossa was explored via an endoscopic endonasal transpterygoid approach. Same surgical dissection procedures were performed on all cadavers: maxillary antrostomy, anterior and posterior ethmoidectomy, sphenoidotomy, transpterygoid pterygopalatine fossa and vidian canal dissection. Mean distance between the anterior nasal spine and ethmoidal crest was 60.35 ± 1.31 mm (range 59-64 mm). Mean distance between the sphenopalatine foramen and superior border of choana was 18.30 ± 1.38 mm (range 17-22 mm). Mean distance...
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To elucidate the variations of the lateral pharyngeal wall anatomy on physical examination and to assess the clinical importance of the examination of the lateral pharyngeal wall on the presence and severity of obstructive sleep apnoea... more
To elucidate the variations of the lateral pharyngeal wall anatomy on physical examination and to assess the clinical importance of the examination of the lateral pharyngeal wall on the presence and severity of obstructive sleep apnoea syndrome. The cross-sectional study was conducted at Ege University Medical School, Izmir, Turkey, between May 2010 and April 2011. The patients were divided into four equal groups: Group 1--snoring without apnoea (age 20-40); Group 2--snoring without apnoea (age 40-60); Group 3--apnoea-hypopnoea index < 5/hr; Group 4: apnoea-hypopnoea index > 30/hr. Calibrated oropharynx pictures were taken. Distance between palatoglossal and palatopharyngeal arches, height of palatoglossal and palatopharyngeal arches, uvula width, uvula length and distance between tonsils were measured. SPSS 17 was used for statistical analysis. Of the 80 patients in the study, 44 (55%) were men. Mean distance between palatopharyngeal and palatoglossal arches were 1.55 ± 0.34 ...
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Research Interests: Surgery, Treatment Outcome, Adolescent, Medicine, Humans, and 14 moreCartilage, Female, Male, Fascia, Clinical Sciences, Middle Aged, Adult, Retrospective Studies, Otolaryngology - Head and Neck Surgery, Audiometry, Tympanic Membrane Perforation, Otolaryngology Head and Neck Surgery, Recovery of Function, and Tympanoplasty
The effect of Sjögren syndrome (SS) on perceptual ratings of the laryngeal findings using the Reflux Finding Score (RFS) and the Reflux Symptom Index (RSI) and the objective voice quality using Jitter (JITT), Pitch Period Perturbation... more
The effect of Sjögren syndrome (SS) on perceptual ratings of the laryngeal findings using the Reflux Finding Score (RFS) and the Reflux Symptom Index (RSI) and the objective voice quality using Jitter (JITT), Pitch Period Perturbation Quotient (PPQ), Shimmer (Shim), Amplitude Perturbation Quotient (APQ) and Noise-to-Harmonic Ratio (NHR) was examined. Seventy-seven patients with SS and seventy-seven healthy individuals for the control group were studied. The Reflux Symptom Index (RSI); nine-item outcomes instrument for assessment of symptoms in patients and the Reflux Finding Score (RFS), eight-item laryngoscopic-based scale for evaluation of laryngeal findings in patients were realised. The Multi Dimensional Voice Program (MDVP) was used for capturing and analysis of the voice samples. For comparison of all parameters of patients and control group subjects, the independent sample t-test was used. The difference of RSI and RFS between patients with SS and control subjects was statistically significant. The difference of voice quality parameters between patients with SS and control subjects expect NHR were statistically significant. There is a significant association between SS and a variety of laryngeal pathologies. The SS patients with reflux symptoms and voice problems must be examined by an ENT specialist and local laryngeal manifestations of SS can be treated symptomatically.
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Background Sphenopalatine artery (SPA) ligation or cauterization stands to be one of the most common management options of refractory epistaxis. Ramification pattern of SPA as it passes through sphenopalatine foramen (SPF) has not been... more
Background Sphenopalatine artery (SPA) ligation or cauterization stands to be one of the most common management options of refractory epistaxis. Ramification pattern of SPA as it passes through sphenopalatine foramen (SPF) has not been clearly established. The aim of this study is to investigate situations in which middle meatal approach may fail due to anatomic variations of SPA and to define a minimally invasive surgical cauterization procedure. Anatomic variations of SPA were determined by microdissection of 20 adult sagittally cross-sectioned head specimens. Methods Branching characteristics of SPA and its anatomic relations were evaluated and anatomic variations were noted. Results SPA was generally (80%) forming branches within SPF before entering into the nasal cavity. In 20% of the specimens, SPF was located superior to the horizontal lamella of the middle turbinate, and accessory foramen was present in 10%. In 10% of the cases, the posterior lateral nasal branch was situate...
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Aberrant course of the internal carotid artery within the middle ear is a rare condition. Surgical interventions following clinical or radiological misinterpretations may lead to fatal complications. A 23-year-old female patient presented... more
Aberrant course of the internal carotid artery within the middle ear is a rare condition. Surgical interventions following clinical or radiological misinterpretations may lead to fatal complications. A 23-year-old female patient presented with a hearing impairment of 10-month duration. On otoscopic examination, the left tympanic membrane was intact, but there was a pulsatile lesion in the tympanic cavity, synchronous with the heartbeats. Pure-tone audiometric examination of the left ear showed a unilateral mixed hearing loss, especially in low frequencies. Computed tomography showed protrusion of the internal carotid artery into the middle ear from the lateral and superior aspects of the cochlea. Magnetic resonance imaging and MR-angiography showed a left-sided deviation of the left internal carotid artery near the cochlea, associated with a filling defect. The caliber of the left internal carotid artery was narrower than the right one in the middle ear, and its proximal part was th...
Research Interests: Magnetic Resonance Imaging, Adolescent, Tinnitus, Case Report, Humans, and 17 moreChild, Female, Male, Young Adult, Differential Diagnosis, Skull Base, Hearing Loss, Clinical Sciences, Aged, Middle Aged, Adult, Temporal Bone, X ray Computed Tomography, Congenital abnormalities, Internal Carotid Artery, Tympanic Membrane, and Magnetic resonance angiography
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Research Interests: Acoustics, Gastroenterology, Speech Acoustics, Treatment Outcome, Risk assessment, and 22 moreProbability, Humans, Female, Male, Statistical Significance, Follow-up studies, Ear Nose and Throat, Esophageal pH monitoring, Voice Quality, Clinical Sciences, Middle Aged, Adult, Risk Assessment, Indexation, Reference Values, Laparoscopy, Gastroesophageal Reflux, Neurosciences, Gastroesophageal Reflux Disease, Case Control Studies, Esophagoscopy, and Postoperative care
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Teratomlar multipl doku yapilari iceren ve kaynaklandigi bolgeden farklilik gosteren gercek neoplazmlar olarak tanimlanabilir. Bas-boyun bolgesi teratomlari nadir gorulur ve bildirilen tum konjenital teratom vakalarinin %2'den azini... more
Teratomlar multipl doku yapilari iceren ve kaynaklandigi bolgeden farklilik gosteren gercek neoplazmlar olarak tanimlanabilir. Bas-boyun bolgesi teratomlari nadir gorulur ve bildirilen tum konjenital teratom vakalarinin %2'den azini olusturur. Konjenital nazofarengeal teratom son derece nadir gorulur ve uygun cerrahi ile prognozu mukemmeldir. Bu olgu sunumunda yarik damagin eslik ettigi konjenital nazofarengeal teratom vakasi sunulmus ve literatur esliginde tartisilmistir.
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Sinonazal bölgenin malign tümörleri, erişkinlerde tüm malign tümörlerin %1’i, baş ve boyun bölgesi malignitelerinin ise %3’ ünü oluşturmaktadır. Bu bölgeye metas taz nadir olmakla birlikte baş ve boyun bölgesine metastaz yapan klavikula... more
Sinonazal bölgenin malign tümörleri, erişkinlerde tüm malign tümörlerin %1’i, baş ve boyun bölgesi malignitelerinin ise %3’ ünü oluşturmaktadır. Bu bölgeye metas taz nadir olmakla birlikte baş ve boyun bölgesine metastaz yapan klavikula altın da yerleşmiş tümörler içerisinde akciğer ve meme malignitelerinden sonra üçün cü sırada renal hücreli karsinom (RHK) gelmektedir. Genelde 40 yaş üstü erkekler de görülen, böbreğin en sık malign tümörü olan RHK; erişkinlerde görülen tüm ma lign tümörlerin %3’ünü oluşturmaktadır ve RHK vakalarının %8’inde hastalık baş boyun bölgesindeki metastaz ile ortaya çıkmaktadır ki bu durum kötü prognostik bir faktördür. Bu makalede RHK nedeniyle 8 yıl önce nefrektomi öyküsü olan, tek rarlayan burun kanaması şikayetiyle başvuran ve nazal kavitede geç dönem RHK metastazı saptanarak cerrahi uygulanan 81 yaşında erkek hasta literatür bilgile ri ile birlikte sunulmuştur.Malign tumors of sinonasal area composes %1 of malignant tumors in adults and %3 of head and...
AN UNUSUAL CAUSE OF NASAL SEPTUM PERFORATION: BACILLARY ANGIOMATOSIS Nazal septum perforasyonlari yasam kalitesini dusuren, bircok hastaliga sekonder olusabilen burun patolojileridir. Basiller anjiyomatozis ise genelllikle immun... more
AN UNUSUAL CAUSE OF NASAL SEPTUM PERFORATION: BACILLARY ANGIOMATOSIS Nazal septum perforasyonlari yasam kalitesini dusuren, bircok hastaliga sekonder olusabilen burun patolojileridir. Basiller anjiyomatozis ise genelllikle immun yetmezligi olan kisilerde gorulen, Bartonellaceae ailesinden bakterilerin neden oldugu, sistemik tutulum yapabilmesine karsin siklikla lokalize mukokutanoz tutulum ile seyreden, tumor benzeri kontrolsuz vaskuler proliferasyona yol acan tedavi edilebilir bir enfeksiyon hastaligidir. Bu yazida, immun yetmezligi olmayan bir hastada nazal kaviteyi tutmus ve nazal septal perforasyona neden olmus bir basiller anjiyomatozis olgusu, literatur bilgileri esliginde sunulmustur. Basiller angiomatozisin izole nazal septal perforasyona neden olmasi literaturde bildirilmis bir durum degildir. Anahtar kelimeler: Basiller anjiyomatozis, nazal septum, perforasyon, bartonellaceae . Abstract Nasal septum perforations are nasal pathologies that decrease the quality of life and ...
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Collision tumors in the paranasal region are extremely rare with limited literature data. To the best of our knowledge, this is the first report of associations of squamous cell carcinoma-esthesioneuroblastoma and... more
Collision tumors in the paranasal region are extremely rare with limited literature data. To the best of our knowledge, this is the first report of associations of squamous cell carcinoma-esthesioneuroblastoma and lymphoma-hemangiopericytoma in the paranasal region. Preoperatively, radiological and clinical findings should be evaluated carefully for the diagnosis and two or more biopsy specimens should be taken from different morphological parts of the lesions. Adjuvant therapy should be planned according to two different histologies and special importance should be given to the tumor which indicates the prognosis of the patient. A multidisciplinary approach is required for the management of synchronous malignancies.