Research Interests:
This paper reports on the chemical compounds in arabica coffee beans with a high Specialty Coffee Association (SCA) cupping score, especially those in specialty coffee beans. We investigated the relationship between the chemical compounds... more
This paper reports on the chemical compounds in arabica coffee beans with a high Specialty Coffee Association (SCA) cupping score, especially those in specialty coffee beans. We investigated the relationship between the chemical compounds and cupping scores by considering 16 types of Coffea arabica (arabica coffee) beans from Guatemala (SCA cupping score of 76.5–89.0 points). Non-targeted gas chromatography-mass spectrometry-based chemometric profiling indicated that specialty beans with a high cupping score contained considerable amounts of methyl-esterified compounds (MECs), including 3-methylbutanoic acid methyl ester (3-MBM), and other fatty acid methyl esters. The effect of MECs on flavor quality was verified by spiking the coffee brew with 3-MBM, which was the top-ranked component, as obtained through a regression model associated with cupping scores. Notably, 3-MBM was responsible for the fresh-fruity aroma and cleanness of the coffee brew. Although cleanness is a significant...
Telah dilakukan isolasi Actinomycetes laut yang mampu menghasilkan senyawa aktif citropeptin yang memiliki efek toksik terhadap sel kanker paru-paru A549. Isolasi dilakukan dengan menggunakan medium agar starch caseinyang ditambah dengan... more
Telah dilakukan isolasi Actinomycetes laut yang mampu menghasilkan senyawa aktif citropeptin yang memiliki efek toksik terhadap sel kanker paru-paru A549. Isolasi dilakukan dengan menggunakan medium agar starch caseinyang ditambah dengan cycloheximidedan nistatin sebagai antifungi serta rifampisin dan nalidixic acids ebagai antibakteri. Sampel sedimen laut diperoleh dari pelabuhan Kamaishi-shi Iwate, Jepang pada kedalaman 5 meter. Dari 71 isolat yang diperoleh, hanya 9 isolat menunjukkan aktivitas terhadap sel kanker A549 pada konsentrasi 1 µg/200 µL. Hasil studi lebih lanjut menunjukkan bahwa isolat RS02-85 yang merupakan isolat terpilih adalah Streptomyces tsukubaensis dengan tingkat kemiripan 98%. Dari hasil identifikasi senyawa aktif, diduga senyawa tersebut adalah citropeptin dengan m/z (M+H)+ 1035,4 g/mol dan rumus molekul C50H82N8O15
Research Interests:
Research Interests:
Research Interests:
ABSTRACT ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select... more
ABSTRACT ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Research Interests:
Research Interests:
Research Interests:
Research Interests:
Research Interests:
Research Interests:
(-)-Thallusin, isolated from a marine bacterium, is the only known natural product to act as an algal morphogenesis inducer. Because (-)-thallusin can only be obtained in exceedingly limited amounts from microbial cultivation, a synthetic... more
(-)-Thallusin, isolated from a marine bacterium, is the only known natural product to act as an algal morphogenesis inducer. Because (-)-thallusin can only be obtained in exceedingly limited amounts from microbial cultivation, a synthetic supply of this compound is highly desirable. Here, we describe a novel synthetic pathway to (±)-thallusin and the first asymmetric synthesis of (-)-thallusin utilizing the enzymatic hydrolysis resolution with the combination of lipase PS-30 and lipase M Amamo-10.
Research Interests:
A new C15 nonterpenoid acetylenic compound, named neoisoprelaurefucin, has been isolated from Laurencia nipponica and its structure deduced from spectroscopic data. Neoisoprelaurefucin is a stereoisomer of (3Z)-isoprelaurefucin, which has... more
A new C15 nonterpenoid acetylenic compound, named neoisoprelaurefucin, has been isolated from Laurencia nipponica and its structure deduced from spectroscopic data. Neoisoprelaurefucin is a stereoisomer of (3Z)-isoprelaurefucin, which has previously been isolated from this species.
Research Interests:
Pergamon 00319422(95)007261 Phytochemistry, Vol. 41, No. 4, pp. 11011103, 1996 Copyright 1996 Elsevier Science Ltd Printed in Great Britain. All rights reserved 00319422 96 15.00 + 0.00 PANNOSALLENE, A BROMINATED C15 NONTERPENOID FROM... more
Pergamon 00319422(95)007261 Phytochemistry, Vol. 41, No. 4, pp. 11011103, 1996 Copyright 1996 Elsevier Science Ltd Printed in Great Britain. All rights reserved 00319422 96 15.00 + 0.00 PANNOSALLENE, A BROMINATED C15 NONTERPENOID FROM LAURENCIA ...
Research Interests:
Research Interests:
Research Interests:
Research Interests:
Research Interests:
Research Interests:
ABSTRACT Total synthesis of (±)-thallusin was achieved using Hg(OTf)2·PhNMe2-induced olefin cyclization, and Suzuki coupling with a pyridylboronic acid derivative. Hg(OTf)2 also acted as a catalyst to isomerize the double bond into the... more
ABSTRACT Total synthesis of (±)-thallusin was achieved using Hg(OTf)2·PhNMe2-induced olefin cyclization, and Suzuki coupling with a pyridylboronic acid derivative. Hg(OTf)2 also acted as a catalyst to isomerize the double bond into the more thermodynamically stable isomer when treated in toluene. Synthetic (±)-thallusin as well as an analogue showed morphogenesis-inducing activity.
Research Interests:
Research Interests:
A novel halogenated acetogenin with a ketonic moiety at C-7, named scanlonenyne, has been isolated from the red alga Laurencia obtusa collected in Irish waters. Its structure was determined by spectroscopic data. ... Structure of... more
A novel halogenated acetogenin with a ketonic moiety at C-7, named scanlonenyne, has been isolated from the red alga Laurencia obtusa collected in Irish waters. Its structure was determined by spectroscopic data. ... Structure of scanlonenyne from the red alga Laurencia obtusa ...
Research Interests:
Ulva and Enteromorpha are cosmopolitan and familiar marine algal genera. It is well known that these green macroalgae lose their natural morphology during short-term cultivation under aseptic conditions and during long-term cultivation in... more
Ulva and Enteromorpha are cosmopolitan and familiar marine algal genera. It is well known that these green macroalgae lose their natural morphology during short-term cultivation under aseptic conditions and during long-term cultivation in nutrient-added seawater and adopt an unusual form instead. These phenomena led to the belief that undefined morphogenetic factors that were indispensable to the foliaceous morphology of macroalgae exist throughout the oceans. We characterize a causative factor, named thallusin, isolated from an epiphytic marine bacterium. Thallusin induces normal germination and morphogenesis of green macroalgae.
Research Interests:
Research Interests:
A new catechol-type siderophore, streptobactin (1), was isolated from a culture broth of the marine-derived actinomycete Streptomyces sp. YM5-799. The structure of streptobactin was determined by NMR and MS analyses and ESIMS/MS... more
A new catechol-type siderophore, streptobactin (1), was isolated from a culture broth of the marine-derived actinomycete Streptomyces sp. YM5-799. The structure of streptobactin was determined by NMR and MS analyses and ESIMS/MS experiments to be a cyclic trimer of benarthin. A dibenarthin (2), a tribenarthin (3), and benarthin (4) were also obtained. The production of 1 was regulated by an iron concentration in the culture. The iron-chelating activity of the compounds was evaluated by the chrome azurol sulfonate assay.
Research Interests:
Research Interests: Genetics, Microbiology, Screening, Cell line, Quantum Coherence, and 15 moreHumans, Spectral analysis, Resistance, Antimicrobial activity, Antimicrobial, Antibiotics, High Resolution, Cell Proliferation, Cytotoxic, Antineoplastic Agents, Geologic Sediments, Nuclear Overhauser Effect, Rifamycins, Glycopeptides, and Pharmacology and pharmaceutical sciences
Research Interests: Genetics, Microbiology, Taxonomy, Magnetic Resonance Spectroscopy, Screening, and 15 moreLung Cancer, Cell line, Humans, Solvent Extraction, Resistance, Stereochemistry, Antibiotics, Fermentation, Silica Gel, Cytotoxic Activity, Water Microbiology, Thiazoles, Glycopeptides, Leucine, and Pharmacology and pharmaceutical sciences
Research Interests:
Research Interests:
Research Interests:
Research Interests: Genetics, Microbiology, Physical Chemistry, Taxonomy, Magnetic Resonance Spectroscopy, and 13 moreScreening, X Rays, Humans, Resistance, Stereochemistry, Cyclic peptides, Antibiotics, Molecular Conformation, Thiazoles, Antitumor Activity, Cytotoxic, Glycopeptides, and Pharmacology and pharmaceutical sciences
Research Interests:
Bacterial strains YM16-303T and YM16-304T were isolated from a sample of seashore sand using a medium with an artificial seawater base. Both isolates grew slowly on marine agar, and were found to be Gram-reaction-positive, aerobic,... more
Bacterial strains YM16-303T and YM16-304T were isolated from a sample of seashore sand using a medium with an artificial seawater base. Both isolates grew slowly on marine agar, and were found to be Gram-reaction-positive, aerobic, non-motile and rod-shaped. The cell-wall peptidoglycan contained ll-diaminopimelic acid, glycine, alanine and hydroxyglutamic acid, and the acyl type of the muramic acid was glycolyl. The predominant menaquinone was MK-9(H8). The 16S rRNA gene sequences of strains YM16-303T and YM16-304T were most similar to that of Ilumatobacter fluminis YM22-133T, and phylogenetic analyses also indicated that they belong to the genus Ilumatobacter . Ilumatobacter fluminis YM22-133T and strains YM16-303T and YM16-304T should be classified as distinct species in the genus Ilumatobacter , however, since the 16S rRNA gene sequence similarity between them was low and the major cellular fatty acids and some physiological properties were different. Moreover, average nucleotide...
Research Interests:
A study was carried out to clarify the taxonomy of four Gram-positive, heterotrophic mesophiles isolated from marine lakes in the Republic of Palau. The strains, designated YM3-251T, YM3-653, YM3-671 and YM11-542T, formed aerial and... more
A study was carried out to clarify the taxonomy of four Gram-positive, heterotrophic mesophiles isolated from marine lakes in the Republic of Palau. The strains, designated YM3-251T, YM3-653, YM3-671 and YM11-542T, formed aerial and substrate mycelia. The cell-wall peptidoglycan contained meso-diaminopimelic acid, glutamic acid and alanine. The G+C content of their genomic DNA was approximately 45 mol%. The major fatty acid was iso-C15 : 0 and the major isoprenoid quinone was MK-9. The strains formed a distinct group in the 16S rRNA gene tree and shared a range of phenotypic properties that distinguished them from members of related genera in Thermoactinomycetaceae fam. nov. The name proposed to accommodate the new isolates is Mechercharimyces gen. nov., comprising two species based on genotypic and phenotypic criteria, including comparative gyrB and DNA–DNA relatedness data. The names proposed for these taxa are Mechercharimyces mesophilus sp. nov., the type species, and Mecherchar...
Research Interests:
Three Gram-stain-positive actinobacterial strains, designated YM24-125T, YM05-1041T and YM12-102T, were isolated from marine environments. Phylogenetic analysis based on 16S rRNA gene sequences indicated that they belonged to the suborder... more
Three Gram-stain-positive actinobacterial strains, designated YM24-125T, YM05-1041T and YM12-102T, were isolated from marine environments. Phylogenetic analysis based on 16S rRNA gene sequences indicated that they belonged to the suborder Micrococcineae and were most closely related to members of the genus Demequina with 95.0–98.4 % sequence similarities. Cells of strains YM05-1041T and YM12-102T were rod-shaped, similar to members of the genus Demequina, while cells of strain YM24-125T were cocci to short ovoid rods. All strains grew in the absence of NaCl, but tolerated up to 15 % NaCl. The major menaquinone was demethylmenaquinone DMK-9 (H4) and the major polar lipids were phosphatidylinositol, diphosphatidylglycerol and phosphatidyglycerol. All strains contained straight-chain, iso-branched and anteiso-branched saturated fatty acids. The DNA G+C contents were 65.3–67.3 mol%. The peptidoglycans of strains YM05-1041T and YM12-102T were the A4β type with ornithine while that of str...
Research Interests:
Description of Persicirhabdus sediminis gen. nov., sp. nov., Roseibacillus ishigakijimensis gen. nov., sp. nov., Roseibacillus ponti sp. nov., Roseibacillus persicicus sp. nov., Luteolibacter pohnpeiensis gen. nov., sp. nov. and Luteolibacter algae sp. nov., six marine members of the phylum 'Verr...more
Research Interests:
Two Gram-negative, non-motile, coccoid or rod-shaped, chemoheterotrophic bacteria designated strains YM21-132T and YM27-005T were isolated from marine animals, and were subjected to a polyphasic taxonomic examination. Phylogenetic... more
Two Gram-negative, non-motile, coccoid or rod-shaped, chemoheterotrophic bacteria designated strains YM21-132T and YM27-005T were isolated from marine animals, and were subjected to a polyphasic taxonomic examination. Phylogenetic analyses based on 16S rRNA gene sequences indicated that the two isolates belong to the genus Rubritalea of the phylum ‘Verrucomicrobia’ (subdivision 1). The novel isolates shared approximately 97–98 % sequence similarity with each other and showed 93–97 % similarity with Rubritalea species of the family Verrucomicrobiaceae. The level of DNA–DNA relatedness between strains YM21-132T and YM27-005T was less than 70 %, which is accepted as the phylogenetic definition of a species. Both strains produced reddish carotenoid pigments and squalene. The cell wall peptidoglycan of both strains contained muramic acid and meso-diaminopimelic acid. The G+C contents of the genomic DNA were 48.0 mol% (strain YM21-132T) and 50.3 mol% (strain YM27-005T). The presence of MK...