The interaction of nutrients, environment, and genome determines the general physiological functi... more The interaction of nutrients, environment, and genome determines the general physiological functioning and health of an organism. The branch of science which aims to understand these interactions is known as “Nutrigenomics.” Aquaculture and fisheries are the fast-growing food production systems and have an important role to play in achieving food and nutritional security. However, like other food production sectors, it also faces numerous challenges. Understanding the nutritional requirements and need-based dietary manipulation are perhaps the most effective and sustainable way of dealing with these challenges. In this review, we discuss the concept of nutrigenomics as a subset of multi-omics technology and highlight some studies encompassing nutrigenomics studies, with a specific focus on its application in fish nutrition. How these emerging techniques are applied in understanding various aspects of fish physiology as influenced by nutrition including nutritional supplements and va...
Mankind has lived with peptic ulcers since ancient times. Peptic ulcers arise due to an imbalance... more Mankind has lived with peptic ulcers since ancient times. Peptic ulcers arise due to an imbalance of acid secretory mechanisms and mucosal protective factors, and their rational treatment is aimed at restoring that balance. For a long time stress and life style were considered the main cause of hyper acid secretion and the resultant inflammation of the stomach (gastritis) as well as ulceration of the stomach or duodenum (peptic ulcer disease). Barry J Marshall and J Robin Warren made the remarkable discovery that gastritis as well as peptic ulcer disease is the result of an infection of the stomach caused by the bacterium Helicobacter pylori, By using technologies generally available and not highly sophisticated, they made an irrefutable case that the H. pylori is responsible for the disease. They devised the culture media for the bacterium so that they were available for scientific studies. The Nobel Prize in Physiology or Medicine for 2005 was awarded jointly to these two Australi...
Abstract A 90 days trial was carried out to investigate the impact of stocking density on growth ... more Abstract A 90 days trial was carried out to investigate the impact of stocking density on growth performances and the health status of Puntius sarana in inland open water cages (Salia Dam of Odisha, India). The fishes of mean body weight 32.04 ± 1.25 g were stocked @ three stocking densities (SD) i.e., 10 m−3 (SD10), 20 m−3 (SD20), and 30 m−3 (SD30) and fed with commercial feed of 28% protein and 4% fat. The growth, in terms of weight gain, specific growth rate, absolute growth rate, percentage survival, protein efficiency ratio, and feed conversion efficiency was significantly decreased (P
The catch pattern of P. indicus in coastal lagoons is influenced by seasonal changes in physicoch... more The catch pattern of P. indicus in coastal lagoons is influenced by seasonal changes in physicochemical parameters of the lagoon ecosystem. In this study the effects of seasonality, salinity and water emperature of lagoon on P. indicus catch were analysed using Structural Time Series Model (STSM) and ARIMAX (Auto Regressive Integrated Moving Average with explanatory variables) modeling approach using monthly time series catch, salinity and water temperature data of the Chilika Lagoon (a Ramsar site) in India for the period from 2001 to 2015. Results showed a significant (p<0.05) increasing stochastic upward trend and two seasonal cycles for P. indicus catch in the lagoon. Salinity was found to have significant positive influence (p<0.05) and temperature to have insignificant positive influence on P. indicus catch in the lagoon.
The present study was undertaken to investigate the alterations in gene expression patterns and f... more The present study was undertaken to investigate the alterations in gene expression patterns and for mutation analysis of p53 in the riverine catfish Rita rita collected from polluted riverine habitat. The partial p53 gene sequence of Rita rita generated showed a high degree of similarities with the DNA binding domains of fishes, mice and human. Transcriptomic analysis, carried out by quantitative real-time Polymerase Chain Reaction (RT-qPCR), showed significant down-regulation of p53 in fishes collected from most of the polluted stretches. Similar trend in protein abundance was observed by western blot analysis. Down-regulation of p53 was more pronounced in gill than liver. Expression patterns of p53 suggest that exposure to a multitude of contaminants in the natural riverine ecosystem could suppress the expression of p53. Genomic DNA showed a low stained smear pattern upon electrophoresis, with no evidence of DNA fragmentation. For mutation analysis PCR-SSCP followed by sequence an...
The present study was undertaken to investigate the proteomic changes in liver of murrel Channa s... more The present study was undertaken to investigate the proteomic changes in liver of murrel Channa striatus exposed to high temperature stress. Fishes were exposed to 36°C for 4 days and liver proteome changes were analyzed using gel- based proteomics i.e. 2D gel electrophoresis, MALDI-TOF/TOF-MS and validation by transcript analysis. The study showed, besides others, increased abundance of two sets of proteins, the antioxidative enzymes SOD, ferritin, CRBP, GST and the chaperones HSP60, PDI; this was validated by transcript analysis. The proteome data are available via ProteomeXchange with identifier PXD002608. Further, gene expression analysis was also carried out in the fishes exposed to thermal stress for longer durations (30 days experimental exposure in laboratory and for 30 days beyond, taking Channa collected from a hot spring runoff at 36-38°C); sod, gst, crbp and hsp60 were found to continue to remain up regulated at 8, 2.5, 2.4 and 2.45 folds, respectively in the hot spring ...
The Indian shad hilsa, Tenualosa ilisha (Hamilton, 1822), is one of the most important tropical f... more The Indian shad hilsa, Tenualosa ilisha (Hamilton, 1822), is one of the most important tropical fishes in the Indo-Pacific region and has occupied a top position among the edible fishes due to its superb taste, mouthwatering flavor and delicate culinary properties. Hilsa is rich in amino acids, minerals and lipids, especially with many essential and poly-unsaturated fatty acids (PUFA). It is found to be beneficial to human health because of very high level of high density lipoprotein and low level of low density lipoprotein in PUFA that reduce the risk of heart disease, diabetes, cancer, obesity, etc. The unique taste of hilsa has been attributed to the presence of many mono and poly unsaturated fatty acids, viz., oleic, lenoleic, lenoleneic, arachidonic, eicosapentaenoeic and docosa-hexaenoeic acids. Hilsa is tastier during pre-spawning than post-spawning or maturing stages. Female hilsa grows faster, attains larger and becomes more tastier than the male of same age group. Riverine...
The interaction of nutrients, environment, and genome determines the general physiological functi... more The interaction of nutrients, environment, and genome determines the general physiological functioning and health of an organism. The branch of science which aims to understand these interactions is known as “Nutrigenomics.” Aquaculture and fisheries are the fast-growing food production systems and have an important role to play in achieving food and nutritional security. However, like other food production sectors, it also faces numerous challenges. Understanding the nutritional requirements and need-based dietary manipulation are perhaps the most effective and sustainable way of dealing with these challenges. In this review, we discuss the concept of nutrigenomics as a subset of multi-omics technology and highlight some studies encompassing nutrigenomics studies, with a specific focus on its application in fish nutrition. How these emerging techniques are applied in understanding various aspects of fish physiology as influenced by nutrition including nutritional supplements and va...
Mankind has lived with peptic ulcers since ancient times. Peptic ulcers arise due to an imbalance... more Mankind has lived with peptic ulcers since ancient times. Peptic ulcers arise due to an imbalance of acid secretory mechanisms and mucosal protective factors, and their rational treatment is aimed at restoring that balance. For a long time stress and life style were considered the main cause of hyper acid secretion and the resultant inflammation of the stomach (gastritis) as well as ulceration of the stomach or duodenum (peptic ulcer disease). Barry J Marshall and J Robin Warren made the remarkable discovery that gastritis as well as peptic ulcer disease is the result of an infection of the stomach caused by the bacterium Helicobacter pylori, By using technologies generally available and not highly sophisticated, they made an irrefutable case that the H. pylori is responsible for the disease. They devised the culture media for the bacterium so that they were available for scientific studies. The Nobel Prize in Physiology or Medicine for 2005 was awarded jointly to these two Australi...
Abstract A 90 days trial was carried out to investigate the impact of stocking density on growth ... more Abstract A 90 days trial was carried out to investigate the impact of stocking density on growth performances and the health status of Puntius sarana in inland open water cages (Salia Dam of Odisha, India). The fishes of mean body weight 32.04 ± 1.25 g were stocked @ three stocking densities (SD) i.e., 10 m−3 (SD10), 20 m−3 (SD20), and 30 m−3 (SD30) and fed with commercial feed of 28% protein and 4% fat. The growth, in terms of weight gain, specific growth rate, absolute growth rate, percentage survival, protein efficiency ratio, and feed conversion efficiency was significantly decreased (P
The catch pattern of P. indicus in coastal lagoons is influenced by seasonal changes in physicoch... more The catch pattern of P. indicus in coastal lagoons is influenced by seasonal changes in physicochemical parameters of the lagoon ecosystem. In this study the effects of seasonality, salinity and water emperature of lagoon on P. indicus catch were analysed using Structural Time Series Model (STSM) and ARIMAX (Auto Regressive Integrated Moving Average with explanatory variables) modeling approach using monthly time series catch, salinity and water temperature data of the Chilika Lagoon (a Ramsar site) in India for the period from 2001 to 2015. Results showed a significant (p<0.05) increasing stochastic upward trend and two seasonal cycles for P. indicus catch in the lagoon. Salinity was found to have significant positive influence (p<0.05) and temperature to have insignificant positive influence on P. indicus catch in the lagoon.
The present study was undertaken to investigate the alterations in gene expression patterns and f... more The present study was undertaken to investigate the alterations in gene expression patterns and for mutation analysis of p53 in the riverine catfish Rita rita collected from polluted riverine habitat. The partial p53 gene sequence of Rita rita generated showed a high degree of similarities with the DNA binding domains of fishes, mice and human. Transcriptomic analysis, carried out by quantitative real-time Polymerase Chain Reaction (RT-qPCR), showed significant down-regulation of p53 in fishes collected from most of the polluted stretches. Similar trend in protein abundance was observed by western blot analysis. Down-regulation of p53 was more pronounced in gill than liver. Expression patterns of p53 suggest that exposure to a multitude of contaminants in the natural riverine ecosystem could suppress the expression of p53. Genomic DNA showed a low stained smear pattern upon electrophoresis, with no evidence of DNA fragmentation. For mutation analysis PCR-SSCP followed by sequence an...
The present study was undertaken to investigate the proteomic changes in liver of murrel Channa s... more The present study was undertaken to investigate the proteomic changes in liver of murrel Channa striatus exposed to high temperature stress. Fishes were exposed to 36°C for 4 days and liver proteome changes were analyzed using gel- based proteomics i.e. 2D gel electrophoresis, MALDI-TOF/TOF-MS and validation by transcript analysis. The study showed, besides others, increased abundance of two sets of proteins, the antioxidative enzymes SOD, ferritin, CRBP, GST and the chaperones HSP60, PDI; this was validated by transcript analysis. The proteome data are available via ProteomeXchange with identifier PXD002608. Further, gene expression analysis was also carried out in the fishes exposed to thermal stress for longer durations (30 days experimental exposure in laboratory and for 30 days beyond, taking Channa collected from a hot spring runoff at 36-38°C); sod, gst, crbp and hsp60 were found to continue to remain up regulated at 8, 2.5, 2.4 and 2.45 folds, respectively in the hot spring ...
The Indian shad hilsa, Tenualosa ilisha (Hamilton, 1822), is one of the most important tropical f... more The Indian shad hilsa, Tenualosa ilisha (Hamilton, 1822), is one of the most important tropical fishes in the Indo-Pacific region and has occupied a top position among the edible fishes due to its superb taste, mouthwatering flavor and delicate culinary properties. Hilsa is rich in amino acids, minerals and lipids, especially with many essential and poly-unsaturated fatty acids (PUFA). It is found to be beneficial to human health because of very high level of high density lipoprotein and low level of low density lipoprotein in PUFA that reduce the risk of heart disease, diabetes, cancer, obesity, etc. The unique taste of hilsa has been attributed to the presence of many mono and poly unsaturated fatty acids, viz., oleic, lenoleic, lenoleneic, arachidonic, eicosapentaenoeic and docosa-hexaenoeic acids. Hilsa is tastier during pre-spawning than post-spawning or maturing stages. Female hilsa grows faster, attains larger and becomes more tastier than the male of same age group. Riverine...
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