248 Result(s)
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Article
Sirtuin 3-activated superoxide dismutase 2 mediates fluoride-induced osteoblastic differentiation in vitro and in vivo by down-regulating reactive oxygen species
Skeletal fluorosis is a chronic metabolic bone disease caused by long-term excessive fluoride intake. Abnormal differentiation of osteoblasts plays an important role in disease progression. Research on the mec...
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SOX9 Promotes Collagen VI Secretion by Upregulating PCOLCE in Neurofibroma
Neurofibromatosis type 1 (NF1) is caused by NF1 gene mutations. Patients with NF1 often have complications with tumors, such as neurofibroma. In order to investigate the pathogenesis of human neurofibroma, a syst...
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Open AccessPolystyrene nanoplastic exposure actives ferroptosis by oxidative stress-induced lipid peroxidation in porcine oocytes during maturation
Polystyrene nanoplastics (PS-NPs) are becoming increasingly prevalent in the environment with great advancements in plastic products, and their potential health hazard to animals has received much attention. S...
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Inflight Performance and Calibrations of the Lyman-Alpha Solar Telescope on Board the Advanced Space-Based Solar Observatory
The Ly α \(\alpha \) Solar Telescope (LST) is the first instrument to achieve ...
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Article
Hydrodynamic performance of an integrated motor pump-jet thruster with gap flow effects
Gap flow has been shown to be the primary aspect of an integrated motor pump-jet (IMP) thruster that cannot be disregarded. In this study, the gap flow was divided into three areas: the rim’s front and rear en...
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Microplastics in soil: a review on research status, sources, methods, and remediation strategies
Microplastics (MPs) are persistent pollutant distributes in sea, soil, and atmosphere widely. Nowadays, there has been an increasing awareness of negative impact of MPs on the environment, especially focusing ...
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Article
Asymmetric Hard X-ray Radiation of Two Ribbons in a Thermal-Dominated C-Class Flare
The asymmetry in hard X-ray (HXR) emission at the footpoints (FPs) of flare loops is a ubiquitous feature closely associated with nonthermal electron transport. In this study, we analyze the asymmetric HXR rad...
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Open AccessNeoadjuvant inetetamab and pertuzumab with taxanes and carboplatin (TCbIP) In locally advanced HER2-positive breast cancer: a prospective cohort study with propensity-matched analysis
Inetetamab is the first domestically developed innovative anti-HER2 monoclonal antibody in China, proven effective and safe in HER2-positive advanced breast cancer. However, its efficacy and safety in neoadjuv...
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Article
Correction to: Association Between a Failed Prominence Eruption and the Drainage of Mass from Another Prominence
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Article
Selective and quasi-continuous switching of ferroelectric Chern insulator devices for neuromorphic computing
Quantum materials exhibit dissipationless topological edge state transport with quantized Hall conductance, offering notable potential for fault-tolerant computing technologies. However, the development of top...
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Open AccessA morphological traits dataset of Heteroptera sampled in biodiversity priority areas of Southwest China
Functional traits reveal the adaptive strategies of species to their environment, and are relevant to the formation of communities, the function of ecosystems, and the mechanisms underlying biodiversity. Howev...
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Article
Waste Control by Waste: Co-Treatment of Municipal Solid Waste Incineration Fly Ash and High Arsenic-Containing Wastewater
In this study, we report the co-treatment of municipal solid waste incineration fly ash and high arsenic-containing wastewater. The appropriate liquid-solid ratio for co-treatment and the feasibility of co-tre...
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Article
Association Between a Failed Prominence Eruption and the Drainage of Mass from Another Prominence
Sympathetic eruptions of solar prominences have been studied for decades, however, it is usually difficult to identify their causal links. Here, we present two failed prominence eruptions on 26 October 2022 an...
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Open AccessHER2-targeting antibody drug conjugate FS-1502 in HER2-expressing metastatic breast cancer: a phase 1a/1b trial
Currently approved HER2-targeting antibody-drug conjugates (ADCs) for HER2-positive breast cancer (BC) are associated with safety concerns. In this multicenter, single-arm, dose-escalation (phase 1a) and dose-...
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Article
Can Industrial Structure Upgrading Restrain Industrial Land Expansion? Evidence from China
China has made great achievements in industrial development and is transforming into a powerful manufacturing country. Meanwhile, the industrial land scale is also expanding. However, whether industrial struct...
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Flaveria bidentis invasion modifies soil physicochemical properties and increases microorganism community diversity
The invasive plant Flaveria bidentis (L.) Kuntze, known as the "ecological killer", poses a significant threat to the ecosystem stability due to its strong phenotypic plasticity and high fertility. Previous studi...
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Article
Open AccessAutomatic Solar Flare Detection Using the Solar Disk Imager Onboard the ASO-S Mission
We present an automated solar flare detection software tool to automatically process solar observed images, detect and track solar flares, and finally compile an event catalog. It can identify and track flares...
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Open AccessSpectral and Imaging Observations of a C2.3 White-Light Flare from the Advanced Space-Based Solar Observatory (ASO-S) and the Chinese H \(\alpha \) Solar Explorer (CHASE)
Solar white-light flares are characterized by an enhancement in the optical continuum, which are usually large flares (X- and M-class flares). Here, we report a small C2.3 white-light flare (SOL2022-12-20T04:1...
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Article
Microstructure Characteristics and Mechanical Properties of γ-TiAl/Steel Joints with Different Laser Pulse Currents
Dissimilar welding of γ-TiAl alloy and steel is applied by laser with different laser pulse current (80A, 85A and 90A). The dissimilar laser weldability of γ-TiAl alloy and steel is investigated on laser welding ...
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Open AccessAuthor Correction: A pipeline contributes to efficient identification of salivary proteins in short-headed planthopper, Epeurysa nawaii