354 Result(s)
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Article
Synergistic Effect of B and Y Micro-alloying on Oxide-Layer Formation on the Super-austenitic S31254 Stainless Steel
Aiming to address the Mo volatilization problem of super-austenitic stainless steel at high temperature, the S31254 steel containing B and rare earth element Y with high oxidation resistance was designed. It w...
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Decolorization of Molasses Wastewater by Immobilized Dual Thermo-Acidophilic Enzymes Under Extreme Conditions
Colorants in molasses wastewater, such as melanoidins and phenols pigment, are rarely degraded through conventional biological processes. Decolorization is the focus of molasses wastewater treatment. Unfortuna...
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Advancing Pyropia kinositae gametophyte cultivation: a study of environmental, physiological, and biochemical factors
Pyropia kinositae, a cold-water red algal species found in East Asian marine environments, thrives on aquaculture rafts and adapts to continuous submersion. Its robust growth and suitability for offshore and nort...
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Open AccessInfluence of AAV vector tropism on long-term expression and Fc-γ receptor binding of an antibody targeting SARS-CoV-2
Long-acting passive immunization strategies are needed to protect immunosuppressed vulnerable groups from infectious diseases. To further explore this concept for COVID-19, we constructed Adeno-associated vira...
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Open AccessMetabolic reprograming mediated by tumor cell-intrinsic type I IFN signaling is required for CD47-SIRPα blockade efficacy
Type I interferons have been well recognized for their roles in various types of immune cells during tumor immunotherapy. However, their direct effects on tumor cells are less understood. Oxidative phosphoryla...
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Author Correction: Obesity induces PD-1 on macrophages to suppress anti-tumour immunity
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Article
The Protective Mechanism of TFAM on Mitochondrial DNA and its Role in Neurodegenerative Diseases
Mitochondrial transcription factor A (TFAM) is a mitochondrial protein encoded by nuclear genes and transported from the cytoplasm to the mitochondria. TFAM is essential for the maintenance, expression, and de...
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Generation and Characterization of Induced Pluripotent Stem Cells Carrying An ASXL1 Mutation
Additional sex combs-like 1 (ASXL1) is an epigenetic modulator frequently mutated in myeloid malignancies, generally associated with poor prognosis. Current models for ASXL1-mutated diseases are mainly based on t...
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Pronunciation guided copy and correction model for ASR error correction
Error correction has proven to be an effective means for refining mistakes produced by Automatic Speech Recognition (ASR) models, thereby contributing to a notable reduction in the Word Error Rate (WER) at the...
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Article
Obesity induces PD-1 on macrophages to suppress anti-tumour immunity
Obesity is a leading risk factor for progression and metastasis of many cancers1,2, yet can in some cases enhance survival3–5 and responses to immune checkpoint blockade therapies, including anti-PD-1, which targ...
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Fabrication of FeSiBPCNbCu nanocrystalline soft magnetic powders with high saturation magnetization and low core loss
In this work, with the aim of developing nanocrystalline powder cores (NPCs) with high saturation magnetization (Ms) and excellent magnetic performances, the structure, crystallization behavior and soft magnetic ...
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Article
You scratch my back and i scratch yours: evidence from relationship-based bidding in IPO auctions
Using a dataset of institutional bids for IPOs, we study how relationships with lead underwriters impact institutional investors’ bidding strategy in the auctioned IPOs. Our paper finds that strong business ti...
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The impact of declarative and interactive carbon disclosure on firm value: complements or substitutes?
The intrinsic link between carbon disclosure and firm value deserves in-depth study in light of the global proposal for “carbon neutrality” and the concurrent advancement of both declarative and interactive ca...
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Open AccessComparative characteristics of early-onset vs. late-onset advanced colorectal cancer: a nationwide study in China
The incidence of early-onset colorectal cancer (EOCRC, diagnosed in patients under the age of 50 years) has been increasing around the world. Here, we aimed to systematically identify distinctive features of E...
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Decorating highly efficient VN quantum dots onto N-doped hollow carbon nanospheres enables effective inhibition of the shuttle effect and acceleration of LiPSs conversion in lithium–sulfur batteries
Lithium-sulfur battery (LSB) is renowned for its high energy density storage property yet its development has faced significant challenges including the shuttle effect and slow reaction rates. A vanadium nitri...
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Article
Preterm Birth Alters the Regional Development and Structural Covariance of Cerebellum at Term-Equivalent Age
Preterm birth is associated with increased risk for a spectrum of neurodevelopmental disabilities. The cerebellum is implicated in a wide range of cognitive functions extending beyond sensorimotor control and ...
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Open AccessProfiling the role of m6A effectors in the regulation of pluripotent reprogramming
The N6-methyladenosine (m6A) RNA modification plays essential roles in multiple biological processes, including stem cell fate determination. To explore the role of the m6A modification in pluripotent reprogrammi...
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Ultrasound-Assisted Accelerated Penetration Extraction of Polyphenols from Pomegranate Peels: Enhanced Mass Transfer by Calcium Ion Precipitation and Utilization of Fick’s Law
The recovery of polyphenols is an attractive strategy for recycling pomegranate peel (PP) and feeding the demands of polyphenol-based functional food. However, emerging techniques are desired to elevate extrac...
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Open AccessConstruction and validation of a hypoxia-related gene signature to predict the prognosis of breast cancer
Among the most common forms of cancer worldwide, breast cancer posed a serious threat to women. Recent research revealed a lack of oxygen, known as hypoxia, was crucial in forming breast cancer. This research ...
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Open AccessMetabolic remodeling by the PD-L1 inhibitor BMS-202 significantly inhibits cell malignancy in human glioblastoma
Recently, crystallographic studies have demonstrated that BMS-202, a small-molecule compound characterized by a methoxy-1-pyridine chemical structure, exhibits a high affinity to PD-L1 dimerization. However, i...