Limas Kupcinskas
Lithuanian University of Health Sciences, Gastroenterology, Faculty Member
Discussions concerning the increased incidence of gastro-oesophageal reflux disease (GORD) after Helicobacter pylori eradication continue. In this study we aimed to evaluate the presence of co-existing GORD in (1) duodenal ulcer patients... more
Discussions concerning the increased incidence of gastro-oesophageal reflux disease (GORD) after Helicobacter pylori eradication continue. In this study we aimed to evaluate the presence of co-existing GORD in (1) duodenal ulcer patients after successful H. pylori eradication, (2) patients with persistent H. pylori infection after attempts at eradication, and (3) controls in whom H. pylori eradication had not been attempted. A prospective study of 255 patients with duodenal ulcer who were assigned to H. pylori eradication or to control treatment (omeprazole for 4 weeks) and followed up for 1 year or until peptic ulcer relapse. GORD was determined in the patients who had reflux oesophagitis on endoscopy at the beginning of the study and/or in patients without reflux oesophagitis if they experienced heartburn and/or regurgitation at least twice a week associated with impairment of daily activities. The study revealed a significant decrease (from 44.6% to 21.7%; P < 0.001) of patien...
Research Interests:
Research Interests:
The prevalence of Helicobacter pylori is high in Eastern Europe. The purpose of this study was to estimate the prevalence of H. pylori in symptomatic Lithuanian children and to identify the infection by clinicopathological and serological... more
The prevalence of Helicobacter pylori is high in Eastern Europe. The purpose of this study was to estimate the prevalence of H. pylori in symptomatic Lithuanian children and to identify the infection by clinicopathological and serological analyses.One hundred sixteen symptomatic children (age 8–16) with gastritis and duodenal ulcer were included. Biopsies were histologically assessed according to the Sydney-System. Serum IgG
Research Interests: Western Europe, Eastern Europe, Immunology, Medical Microbiology, Helicobacter pylori, and 16 moreAdolescent, Humans, Child, Female, Male, Lithuania, Epidemiology of Helicobacter pylori infection, Prevalence, Gold Standard, Western blot, Gastritis, Enzyme Linked Immunosorbent Assay, Low molecular weight, H Pylori, immunoglobulin G, and Duodenal Ulcer
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Research Interests:
Research Interests: Immunology, Research Design, Psychometrics, Clinical Trial, Diabetes, and 59 moreQuality of life, Treatment Outcome, Adolescent, Spain, Heart Failure, Social behavior, Factor analysis, Prospective studies, Allergy, Humans, Child, Developing Country, Liver Cirrhosis, Diabetes mellitus, World, Health related Quality of Life, Effect size, Physical Health, Female, Male, Young Adult, Conceptual Model, Laryngopharyngeal reflux, Patient Satisfaction, Data Collection, STEM (short form), Immunoglobulin E, Left Ventricular Dysfunction, Lithuania, Psychometric Properties, Meta Analysis, Systematic review, Health Status, Clinical Sciences, Aged, Middle Aged, Questionnaires, Social Functioning, Adult, Esophagus, Public health systems and services research, Chronic Heart Failure, Sex Factors, Delivery System, Age Factors, Social Behavior, Quality Life, Case Control Study, Chest Pain, Laparoscopy, Neurosciences, Chronic Liver Disease, Confidence Interval, Metabolic control, Control Group, Case Control Studies, Esophagoscopy, Dilatation, and Severity of Illness Index
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Research Interests:
Research Interests:
We performed a genome-wide association analysis of 1,897,764 SNPs in 1,043 German ulcerative colitis (UC) cases and 1,703 controls. We discovered new associations at chromosome 7q22 (rs7809799) and at chromosome 22q13 in IL17REL... more
We performed a genome-wide association analysis of 1,897,764 SNPs in 1,043 German ulcerative colitis (UC) cases and 1,703 controls. We discovered new associations at chromosome 7q22 (rs7809799) and at chromosome 22q13 in IL17REL (rs5771069) and confirmed these associations in six replication panels (2,539 UC cases and 5,428 controls) from different regions of Europe (overall study sample P(rs7809799) = 8.81 x 10(-11) and P(rs5771069) = 4.21 x 10(-8), respectively).
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Research Interests:
Research Interests:
Research Interests:
Research Interests: Polymorphism, Treatment Outcome, Helicobacter pylori, Biological Sciences, Humans, and 20 moreChild, Developing Country, Animals, Dyspepsia, Cost effectiveness, Risk factors, Prevalence, Middle Aged, Gene Polymorphism, Anti-Bacterial Agents, Combination drug therapy, Risk Factors, Peptic Ulcer, Peptic Ulcer Disease, Gastroesophageal Reflux, Gastroesophageal Reflux Disease, H Pylori, Duodenal Ulcer, Gastrointestinal Diseases, and Clinical Trials as Topic
Research Interests: Psychotherapy, Evidence Based Medicine, Quality of life, Biopsy, Inflammatory Bowel Disease, and 28 morePregnancy, Humans, Europe, Consensus, Ulcerative colitis, Organizations, Complementary Therapies, Female, Drug Resistance, Monoclonal Antibodies, Arthritis, Risk factors, Randomised Controlled Trial, Skin Diseases, Recurrence, Clinical Sciences, Anti-Bacterial Agents, Gastrointestinal Endoscopy, Methotrexate, Physical examination, Gut, Risk Factors, SECONDARY PREVENTION, Crohn Disease, Pregnancy Outcome, Mesalamine Uk, Mesalamine, and Clinical Trials as Topic
No abstract is available. To read the body of this article, please view the PDF online. ... © 2010 AGA. Published by Elsevier Inc. All rights reserved. ... Visit SciVerse ScienceDirect to see if you have access via your institution. ...... more
No abstract is available. To read the body of this article, please view the PDF online. ... © 2010 AGA. Published by Elsevier Inc. All rights reserved. ... Visit SciVerse ScienceDirect to see if you have access via your institution. ... Advertisements on this site do not constitute a ...