Location via proxy:   [ UP ]  
[Report a bug]   [Manage cookies]                
Prijeđi na sadržaj

Eltoprazin

Izvor: Wikipedija
Eltoprazin
(IUPAC) ime
1-(2,3-dihidro-1,4-benzodioksin-8-il)piperazin
Klinički podaci
Identifikatori
CAS broj 98224-03-4
ATC kod nije dodeljen
PubChem[1][2] 65853
ChemSpider[3] 59265
UNII 510M006KO6 DaY
ChEMBL[4] CHEMBL282614
Hemijski podaci
Formula C12H16N2O2 
Mol. masa 220.121 g/mol
SMILES eMolekuli & PubHem
Farmakoinformacioni podaci
Trudnoća ?
Pravni status

Eltoprazin (DU-28,853) je lek iz fenilpiperazinske klase. On je antiagresivni agens.[5] Eltoprazin deluje kao agonist na 5-HT1A i 5-HT1B receptorima i kao antagonist na 5-HT2C receptor.[6] On je blisko srodan sa fluprazinom i batoprazinom, koji imaju slično dejstvo.

Reference

[uredi | uredi kod]
  1. Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519.  edit
  2. Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1. 
  3. Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846.  edit
  4. Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948594.  edit
  5. Olivier B, Mos J, Rasmussen D. (1990). „Behavioural pharmacology of the serenic, eltoprazine”. Drug Metabol Drug Interact. 8 (1-2): 31–83. DOI:10.1515/DMDI.1990.8.1-2.31. PMID 2091890. 
  6. Schipper J, Tulp MT, Sijbesma H. (1990). „Neurochemical profile of eltoprazine.”. Drug Metabol Drug Interact. 8 (1-2): 85–114. PMID 1982626. 

Povezano

[uredi | uredi kod]

Vanjske veze

[uredi | uredi kod]