Receptor slobodnih masnih kiselina 3
| edit |
| Receptor slobodnih masnih kiselina 3 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||||
| Simboli | FFAR3; FFA3R; GPR41 | ||||||||||
| Vanjski ID | OMIM: 603821 MGI: 2685324 HomoloGene: 82482 IUPHAR: FFA3 GeneCards: FFAR3 Gene | ||||||||||
| |||||||||||
| Ortolozi | |||||||||||
| Vrsta | Čovek | Miš | |||||||||
| Entrez | 2865 | 233080 | |||||||||
| Ensembl | ENSG00000185897 | ENSMUSG00000019429 | |||||||||
| UniProt | O14843 | Q3UFD7 | |||||||||
| RefSeq (mRNA) | NM_005304.3 | NM_001033316.2 | |||||||||
| RefSeq (protein) | NP_005295.1 | NP_001028488.1 | |||||||||
| Lokacija (UCSC) | Chr 19: 35.85 - 35.85 Mb | Chr 7: 31.64 - 31.64 Mb | |||||||||
| PubMed pretraga | [1] | [2] | |||||||||
Receptor slobodnih masnih kiselina 3 (FFA3) je G protein spregnuti receptor koji je kod ljudi kodiran FFAR3 genom.[1][2]
- ↑ „Entrez Gene: FFAR3 free fatty acid receptor 3”.
- ↑ Sawzdargo M, George SR, Nguyen T, Xu S, Kolakowski LF, O'Dowd BF (October 1997). „A cluster of four novel human G protein-coupled receptor genes occurring in close proximity to CD22 gene on chromosome 19q13.1”. Biochem. Biophys. Res. Commun. 239 (2): 543–7. DOI:10.1006/bbrc.1997.7513. PMID 9344866.
- Brown AJ, Jupe S, Briscoe CP (2005). „A family of fatty acid binding receptors.”. DNA Cell Biol. 24 (1): 54–61. DOI:10.1089/dna.2005.24.54. PMID 15684720.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). „Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.”. Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. DOI:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Brown AJ, Goldsworthy SM, Barnes AA, et al. (2003). „The Orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids.”. J. Biol. Chem. 278 (13): 11312–9. DOI:10.1074/jbc.M211609200. PMID 12496283.
- Le Poul E, Loison C, Struyf S, et al. (2003). „Functional characterization of human receptors for short chain fatty acids and their role in polymorphonuclear cell activation.”. J. Biol. Chem. 278 (28): 25481–9. DOI:10.1074/jbc.M301403200. PMID 12711604.
- Xiong Y, Miyamoto N, Shibata K, et al. (2004). „Short-chain fatty acids stimulate leptin production in adipocytes through the G protein-coupled receptor GPR41.”. Proc. Natl. Acad. Sci. U.S.A. 101 (4): 1045–50. DOI:10.1073/pnas.2637002100. PMC 327148. PMID 14722361.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). „The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”. Genome Res. 14 (10B): 2121–7. DOI:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Yonezawa T, Kobayashi Y, Obara Y (2007). „Short-chain fatty acids induce acute phosphorylation of the p38 mitogen-activated protein kinase/heat shock protein 27 pathway via GPR43 in the MCF-7 human breast cancer cell line.”. Cell. Signal. 19 (1): 185–93. DOI:10.1016/j.cellsig.2006.06.004. PMID 16887331.